메뉴 건너뛰기




Volumn 2012, Issue , 2012, Pages

Toxin-based targeted therapy for malignant brain tumors

Author keywords

[No Author keywords available]

Indexed keywords

CRM 107; CYTOTOXIN; DIPHTHERIA TOXIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 3; GLYCOPROTEIN; GLYCOPROTEIN NONMETASTATIC MELANOMA PROTEIN B; HIGH MOLECULAR WEIGHT MELANOMA ASSOCIATED ANTIGEN; IMMUNOTOXIN; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; MEMBRANE PROTEIN; PSEUDOMONAS EXOTOXIN; PSEUDOMONAS EXOTOXIN A; RICIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; UROKINASE RECEPTOR; HYBRID PROTEIN; TUMOR ANTIGEN;

EID: 84858208091     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/480429     Document Type: Review
Times cited : (29)

References (147)
  • 1
    • 0029094065 scopus 로고
    • A tiger behind many doors: Multiple genetic pathways to malignant glioma
    • Louis D. N., Gusella J. F., A tiger behind many doors: multiple genetic pathways to malignant glioma Trends in Genetics 1995 11 10 412 415
    • (1995) Trends in Genetics , vol.11 , Issue.10 , pp. 412-415
    • Louis, D.N.1    Gusella, J.F.2
  • 2
    • 0032729320 scopus 로고    scopus 로고
    • The effect of extent of resection on time to tumor progression and survival in patients with glioblastoma multiforme of the cerebral hemisphere
    • DOI 10.1016/S0090-3019(99)00103-2, PII S0090301999001032
    • Keles G. E., Anderson B., Berger M. S., The effect of extent of resection on time to tumor progression and survival in patients with glioblastoma multiforme of the cerebral hemisphere Surgical Neurology 1999 52 4 371 379 (Pubitemid 29505267)
    • (1999) Surgical Neurology , vol.52 , Issue.4 , pp. 371-379
    • Keles, G.E.1    Anderson, B.2    Berger, M.S.3
  • 3
    • 0028266108 scopus 로고
    • Contemporary approaches to the treatment of malignant gliomas with radiation therapy
    • Leibel S. A., Scott C. B., Loeffler J. S., Contemporary approaches to the treatment of malignant gliomas with radiation therapy Seminars in Oncology 1994 21 2 198 219 (Pubitemid 24125959)
    • (1994) Seminars in Oncology , vol.21 , Issue.2 , pp. 198-219
    • Leibel, S.A.1    Scott, C.B.2    Loeffler, J.S.3
  • 4
    • 0028353403 scopus 로고
    • The chemotherapy of high-grade astrocytomas
    • Lesser G. J., Grossman S., The chemotherapy of high-grade astrocytomas Seminars in Oncology 1994 21 2 220 235 (Pubitemid 24125960)
    • (1994) Seminars in Oncology , vol.21 , Issue.2 , pp. 220-235
    • Lesser, G.J.1    Grossman, S.2
  • 6
    • 80855145598 scopus 로고    scopus 로고
    • Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy
    • Reardon D. A., Desjardins A., Peters K. B., Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy Cancer 2011 117 23 5351 5358
    • (2011) Cancer , vol.117 , Issue.23 , pp. 5351-5358
    • Reardon, D.A.1    Desjardins, A.2    Peters, K.B.3
  • 8
    • 0025668599 scopus 로고
    • Effects of treatment on long-term survivors with malignant astrocytomas
    • Imperato J. P., Paleologos N. A., Vick N. A., Effects of treatment on long-term survivors with malignant astrocytomas Annals of Neurology 1990 28 6 818 822
    • (1990) Annals of Neurology , vol.28 , Issue.6 , pp. 818-822
    • Imperato, J.P.1    Paleologos, N.A.2    Vick, N.A.3
  • 11
    • 0025688669 scopus 로고
    • Structure, function, and clinical significance of human tumor antigens
    • Herlyn M., Menrad A., Koprowski H., Structure, function, and clinical significance of human tumor antigens Journal of the National Cancer Institute 1990 82 24 1883 1889
    • (1990) Journal of the National Cancer Institute , vol.82 , Issue.24 , pp. 1883-1889
    • Herlyn, M.1    Menrad, A.2    Koprowski, H.3
  • 12
    • 0028048221 scopus 로고
    • Targeted toxins as anticancer agents
    • Siegall C. B., Targeted toxins as anticancer agents Cancer 1994 74 3 1006 1012 (Pubitemid 24231995)
    • (1994) Cancer , vol.74 , Issue.3 , pp. 1006-1012
    • Siegall, C.B.1
  • 13
    • 0014931204 scopus 로고
    • Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells
    • Moolten F. L., Cooperband S. R., Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells Science 1970 169 3940 68 70
    • (1970) Science , vol.169 , Issue.3940 , pp. 68-70
    • Moolten, F.L.1    Cooperband, S.R.2
  • 15
    • 0016358276 scopus 로고
    • Mechanism of action of the toxic lectins abrin and ricin
    • Olsnes S., Refsnes K., Pihl A., Mechanism of action of the toxic lectins abrin and ricin Nature 1974 249 5468 627 631
    • (1974) Nature , vol.249 , Issue.5468 , pp. 627-631
    • Olsnes, S.1    Refsnes, K.2    Pihl, A.3
  • 16
    • 81555214408 scopus 로고    scopus 로고
    • A guide to taming a toxinrecombinant immunotoxins constructed from pseudomonas exotoxin a for the treatment of cancer
    • Weldon J. E., Pastan I., A guide to taming a toxinrecombinant immunotoxins constructed from pseudomonas exotoxin a for the treatment of cancer FEBS Journal 2011 278 23 4683 4700
    • (2011) FEBS Journal , vol.278 , Issue.23 , pp. 4683-4700
    • Weldon, J.E.1    Pastan, I.2
  • 17
    • 0016733731 scopus 로고
    • Effects of ricin on the ribosomal sites involved in the interaction of the elongation factors
    • Carrasco L., Fernandez Puentes C., Vazquez D., Effects of ricin on the ribosomal sites involved in the interaction of the elongation factors European Journal of Biochemistry 1975 54 2 499 503
    • (1975) European Journal of Biochemistry , vol.54 , Issue.2 , pp. 499-503
    • Carrasco, L.1    Fernandez Puentes, C.2    Vazquez, D.3
  • 18
    • 0018167496 scopus 로고
    • One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
    • Yamaizumi M., Mekada E., Uchida T., Okada Y., One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell Cell 1978 15 1 245 250 (Pubitemid 9027527)
    • (1978) Cell , vol.15 , Issue.1 , pp. 245-250
    • Yamaizumi, M.1    Mekada, E.2    Uchida, T.3    Okada, Y.4
  • 19
    • 0019309042 scopus 로고
    • Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
    • DOI 10.1016/0014-4827(80)90270-0
    • Eiklid K., Olsnes S., Pihl A., Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells Experimental Cell Research 1980 126 2 321 326 (Pubitemid 10041165)
    • (1980) Experimental Cell Research , vol.126 , Issue.2 , pp. 321-326
    • Eiklid, K.1    Olsnes, S.2    Pihl, A.3
  • 21
    • 0023657391 scopus 로고
    • Functional domains of pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli
    • Hwang J., Fitzgerald D. J., Adhya S., Pastan I., Functional domains of pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli Cell 1987 48 1 129 136
    • (1987) Cell , vol.48 , Issue.1 , pp. 129-136
    • Hwang, J.1    Fitzgerald, D.J.2    Adhya, S.3    Pastan, I.4
  • 24
  • 27
    • 0026747170 scopus 로고
    • Expression cloning of a Diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
    • Naglich J. G., Metherall J. E., Russell D. W., Eidels L., Expression cloning of a Diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor Cell 1992 69 6 1051 1061
    • (1992) Cell , vol.69 , Issue.6 , pp. 1051-1061
    • Naglich, J.G.1    Metherall, J.E.2    Russell, D.W.3    Eidels, L.4
  • 29
    • 0019271816 scopus 로고
    • Diphtheria toxin entry into cells is facilitated by low pH
    • 3 I, DOI 10.1083/jcb.87.3.828
    • Sandvig K., Olsnes S., Diphtheria toxin entry into cells is facilitated by low pH Journal of Cell Biology 1980 87 3 828 832 (Pubitemid 11161814)
    • (1980) Journal of Cell Biology , vol.87 , pp. 828-832
    • Sandvig, K.1    Olsnes, S.2
  • 30
    • 0000493971 scopus 로고
    • Studies on the mode of action of diphtheria toxin. II. Effect of toxin on amino acid incorporation in cell-free systems
    • Collier R. J., Pappenheimer A. M. Jr., Studies on the mode of action of diphtheria toxin. II. Effect of toxin on amino acid incorporation in cell-free systems Journal of Experimental Medicine 1964 120 1019 1039
    • (1964) Journal of Experimental Medicine , vol.120 , pp. 1019-1039
    • Collier, R.J.1    Pappenheimer, Jr.A.M.2
  • 31
    • 0014429772 scopus 로고
    • Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis
    • Honjo T., Nishizuka Y., Hayaishi O., Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis Journal of Biological Chemistry 1968 243 12 3553 3555
    • (1968) Journal of Biological Chemistry , vol.243 , Issue.12 , pp. 3553-3555
    • Honjo, T.1    Nishizuka, Y.2    Hayaishi, O.3
  • 32
    • 0019333247 scopus 로고
    • ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products
    • Van Ness B. G., Howard J. B., Bodley J. W., ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products Journal of Biological Chemistry 1980 255 22 10717 10720
    • (1980) Journal of Biological Chemistry , vol.255 , Issue.22 , pp. 10717-10720
    • Van Ness, B.G.1    Howard, J.B.2    Bodley, J.W.3
  • 33
  • 34
    • 0015781481 scopus 로고
    • Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
    • Olsnes S., Pihl A., Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis Biochemistry 1973 12 16 3121 3126
    • (1973) Biochemistry , vol.12 , Issue.16 , pp. 3121-3126
    • Olsnes, S.1    Pihl, A.2
  • 36
    • 0015801981 scopus 로고
    • Inhibition by ricin of protein synthesis in vitro: 60 S ribosomal subunit as the target of the toxin
    • Sperti S., Montanaro L., Mattioli A., Stirpe F., Inhibition by ricin of protein synthesis in vitro: 60 S ribosomal subunit as the target of the toxin Biochemical Journal 1973 136 3 813 815
    • (1973) Biochemical Journal , vol.136 , Issue.3 , pp. 813-815
    • Sperti, S.1    Montanaro, L.2    Mattioli, A.3    Stirpe, F.4
  • 37
    • 0023664263 scopus 로고
    • The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins
    • Endo Y., Mitsui K., Motizuki M., Tsurugi K., The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins Journal of Biological Chemistry 1987 262 12 5908 5912
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.12 , pp. 5908-5912
    • Endo, Y.1    Mitsui, K.2    Motizuki, M.3    Tsurugi, K.4
  • 38
    • 0031451777 scopus 로고    scopus 로고
    • Tumor regression with regional distribution of the targeted toxin TF- CRM107 in patients with malignant brain tumors
    • DOI 10.1038/nm1297-1362
    • Laske D. W., Youle R. J., Oldfield E. H., Tumor regression with regional distribution of the targeted toxin TF- CRM107 in patients with malignant brain tumors Nature Medicine 1997 3 12 1362 1368 (Pubitemid 28011036)
    • (1997) Nature Medicine , vol.3 , Issue.12 , pp. 1362-1368
    • Laske, D.W.1    Youle, R.J.2    Oldfield, E.H.3
  • 39
    • 0344876636 scopus 로고    scopus 로고
    • Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) therapy of malignant gliomas
    • DOI 10.1023/A:1026246500788
    • Weaver M., Laske D. W., Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) therapy of malignant gliomas Journal of Neuro-Oncology 2003 65 1 3 13 (Pubitemid 37441310)
    • (2003) Journal of Neuro-Oncology , vol.65 , Issue.1 , pp. 3-13
    • Weaver, M.1    Laske, D.W.2
  • 41
    • 0034047780 scopus 로고    scopus 로고
    • Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma
    • Rand R. W., Kreitman R. J., Patronas N., Varricchio F., Pastan I., Puri R. K., Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma Clinical Cancer Research 2000 6 6 2157 2165 (Pubitemid 30399180)
    • (2000) Clinical Cancer Research , vol.6 , Issue.6 , pp. 2157-2165
    • Rand, R.W.1    Kreitman, R.J.2    Patronas, N.3    Varricchio, F.4    Pastan, I.5    Puri, R.K.6
  • 44
    • 39449114014 scopus 로고    scopus 로고
    • Clinical trials with intracerebral convection-enhanced delivery of targeted toxins in malignant glioma
    • DOI 10.2174/157488708783330521
    • Rainov N. G., Gorbatyuk K., Heidecke V., Clinical trials with intracerebral convection-enhanced delivery of targeted toxins in malignant glioma Reviews on Recent Clinical Trials 2008 3 1 2 9 (Pubitemid 351267022)
    • (2008) Reviews on Recent Clinical Trials , vol.3 , Issue.1 , pp. 2-9
    • Rainov, N.G.1    Gorbatyuk, K.2    Heidecke, V.3
  • 47
    • 11344291098 scopus 로고    scopus 로고
    • Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice
    • Liu T. F., Hall P. D., Cohen K. A., Willingham M. C., Cai J., Thorburn A., Frankel A. E., Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice Clinical Cancer Research 2005 11 1 329 334 (Pubitemid 40075812)
    • (2005) Clinical Cancer Research , vol.11 , Issue.1 , pp. 329-334
    • Liu, T.F.1    Hall, P.D.2    Cohen, K.A.3    Willingham, M.C.4    Cai, J.5    Thorburn, A.6    Frankel, A.E.7
  • 50
    • 0021856307 scopus 로고
    • Applications of monoclonal antibodies in the diagnosis and treatment of primary brain tumors
    • Bullard D. E., Bigner D. D., Applications of monoclonal antibodies in the diagnosis and treatment of primary brain tumors Journal of Neurosurgery 1985 63 1 2 16 (Pubitemid 15067265)
    • (1985) Journal of Neurosurgery , vol.63 , Issue.1 , pp. 2-16
    • Bullard, D.E.1    Bigner, D.D.2
  • 52
    • 0020597630 scopus 로고
    • Transferrin receptors in human tissues: Their distribution and possible clinical relevance
    • Gatter K. C., Brown G., Trowbridge I. S., Woolston R. E., Mason D. Y., Transferrin receptors in human tissues: their distribution and possible clinical relevance Journal of Clinical Pathology 1983 36 5 539 545 (Pubitemid 13089724)
    • (1983) Journal of Clinical Pathology , vol.36 , Issue.5 , pp. 539-545
    • Gatter, K.C.1    Brown, G.2    Strowbridge, I.3
  • 53
    • 0019833023 scopus 로고
    • Anti-transferrin receptor monoclonal antibody and toxin-antibody conjugates affect growth of human tumour cells
    • Trowbridge I. S., Domingo D. L., Anti-transferrin receptor monoclonal antibody and toxin-antibody conjugates affect growth of human tumour cells Nature 1981 294 5837 171 173 (Pubitemid 12217978)
    • (1981) Nature , vol.294 , Issue.5837 , pp. 171-173
    • Trowbridge, I.S.1    Domingo, D.L.2
  • 54
    • 0025165507 scopus 로고
    • Potent cytotoxicity of an antihuman transferrin receptor-ricin A-chain immunotoxin on human glioma cells in vitro
    • Recht L. D., Griffin T. W., Raso V., Salimi A. R., Potent cytotoxicity of an antihuman transferrin receptor-ricin A-chain immunotoxin on human glioma cells in vitro Cancer Research 1990 50 20 6696 6700 (Pubitemid 20348802)
    • (1990) Cancer Research , vol.50 , Issue.20 , pp. 6696-6700
    • Recht, L.D.1    Griffin, T.W.2    Raso, V.3    Salimi, A.R.4
  • 55
    • 0023194662 scopus 로고
    • Potent and specific killing of human malignant brain tumor cells by an anti-transferrin receptor antibody-ricin immunotoxin
    • Zovickian J., Johnson V. G., Youle R. J., Potent and specific killing of human malignant brain tumor cells by an anti-transferrin receptor antibody-ricin immunotoxin Journal of Neurosurgery 1987 66 6 850 861 (Pubitemid 17085706)
    • (1987) Journal of Neurosurgery , vol.66 , Issue.6 , pp. 850-861
    • Zovickian, J.1    Gray Johnson, V.2    Youle, R.J.3
  • 56
    • 0023205060 scopus 로고
    • Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity
    • Greenfield L., Johnson V. G., Youle R. J., Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity Science 1987 238 4826 536 539 (Pubitemid 17147040)
    • (1987) Science , vol.238 , Issue.4826 , pp. 536-539
    • Greenfield, L.1    Johnson, V.G.2    Youle, R.J.3
  • 57
    • 0028273552 scopus 로고
    • Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice
    • Laske D. W., Ilercil O., Akbasak A., Youle R. J., Oldfield E. H., Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice Journal of Neurosurgery 1994 80 3 520 526 (Pubitemid 24073015)
    • (1994) Journal of Neurosurgery , vol.80 , Issue.3 , pp. 520-526
    • Laske, D.W.1    Ilercil, O.2    Akbasak, A.3    Youle, R.J.4    Oldfield, E.H.5
  • 58
    • 0027474795 scopus 로고
    • Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors
    • Martell L. A., Agrawal A., Ross D. A., Muraszko K. M., Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors Cancer Research 1993 53 6 1348 1353 (Pubitemid 23097115)
    • (1993) Cancer Research , vol.53 , Issue.6 , pp. 1348-1353
    • Martell, L.A.1    Agrawal, A.2    Ross, D.A.3    Muraszko, K.M.4
  • 60
    • 0022624548 scopus 로고
    • Combination intraventricular chemotherapy for meningeal neoplasia
    • Giannone L., Greco F. A., Hainsworth J. D., Combination intraventricular chemotherapy for meningeal neoplasia Journal of Clinical Oncology 1986 4 1 68 73 (Pubitemid 16155963)
    • (1986) Journal of Clinical Oncology , vol.4 , Issue.1 , pp. 68-73
    • Giannone, L.1    Greco, F.A.2    Hainsworth, J.D.3
  • 62
    • 0033010373 scopus 로고    scopus 로고
    • The IL-4 receptor: Signaling mechanisms and biologic functions
    • DOI 10.1146/annurev.immunol.17.1.701
    • Nelms K., Keegan A. D., Zamorano J., Ryan J. J., Paul W. E., The IL-4 receptor: signaling mechanisms and biologic functions Annual Review of Immunology 1999 17 701 738 (Pubitemid 29241138)
    • (1999) Annual Review of Immunology , vol.17 , pp. 701-738
    • Nelms, K.1    Keegan, A.D.2    Zamorano, J.3    Ryan, J.J.4    Paul, W.E.5
  • 63
    • 0027731604 scopus 로고
    • Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4
    • Kondo M., Takeshita T., Ishii N., Nakamura M., Watanabe S., Arai K., Sugamura K., Sharing of the interleukin-2 (IL-2) receptor chain between receptors for IL-2 and IL-4 Science 1993 262 5141 1874 1877 (Pubitemid 24041858)
    • (1993) Science , vol.262 , Issue.5141 , pp. 1874-1877
    • Kondo, M.1    Takeshita, T.2    Ishii, N.3    Nakamura, M.4    Watanabe, S.5    Arai, K.-I.6    Sugamura, K.7
  • 65
    • 0028917463 scopus 로고
    • Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common chain shared by receptors for interleukins 2, 4, 7, 9, and 15
    • Obiri N. I., Debinski W., Leonard W. J., Puri R. K., Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common chain shared by receptors for interleukins 2, 4, 7, 9, and 15 Journal of Biological Chemistry 1995 270 15 8797 8804
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.15 , pp. 8797-8804
    • Obiri, N.I.1    Debinski, W.2    Leonard, W.J.3    Puri, R.K.4
  • 66
    • 0031568012 scopus 로고    scopus 로고
    • The IL-13 Receptor Structure Differs on Various Cell Types and May Share More Than One Component with IL-4 Receptor
    • Obiri N. I., Leland P., Murata T., Debinski W., Puri R. K., The IL-13 receptor structure differs on various cell types and may share more than one component with il-4 receptor Journal of Immunology 1997 158 2 756 764 (Pubitemid 127492652)
    • (1997) Journal of Immunology , vol.158 , Issue.2 , pp. 756-764
    • Obiri, N.I.1    Leland, P.2    Murata, T.3    Debinski, W.4    Puri, R.K.5
  • 67
    • 0027469405 scopus 로고
    • Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin- 4
    • Obiri N. I., Hillman G. G., Haas G. P., Sud S., Puri R. K., Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin- 4 Journal of Clinical Investigation 1993 91 1 88 93 (Pubitemid 23037257)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.1 , pp. 88-93
    • Obiri, N.I.1    Hillman, G.G.2    Haas, G.P.3    Sud, S.4    Puri, R.K.5
  • 68
    • 0028321590 scopus 로고
    • Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells
    • Obiri N. I., Siegel J. P., Varricchio F., Puri R. K., Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells Clinical and Experimental Immunology 1994 95 1 148 155 (Pubitemid 24207118)
    • (1994) Clinical and Experimental Immunology , vol.95 , Issue.1 , pp. 148-155
    • Obiri, N.I.1    Siegel, J.P.2    Varricchio, F.3    Puri, R.K.4
  • 69
    • 0027315711 scopus 로고
    • A wide range of human cancers express interleukin 4 (IL4) receptors that can be targeted with chimeric toxin composed of IL4 and Pseudomonas exotoxin
    • Debinski W., Puri R. K., Kreitman R. J., Pastan I., A wide range of human cancers express interleukin 4 (IL4) receptors that can be targeted with chimeric toxin composed of IL4 and Pseudomonas exotoxin Journal of Biological Chemistry 1993 268 19 14065 14070 (Pubitemid 23195524)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.19 , pp. 14065-14070
    • Debinski, W.1    Puri, R.K.2    Kreitman, R.J.3    Pastan, I.4
  • 70
    • 0028353277 scopus 로고
    • Human renal cell carcinoma cells are sensitive to the cytotoxic effect of a chimeric protein composed of human interleukin-4 and Pseudomonas exotoxin
    • DOI 10.1006/cimm.1994.1084
    • Puri R. K., Debinski W., Obiri N., Kreitman R., Pastan I., Human renal cell carcinoma cells are sensitive to the cytotoxic effect of a chimeric protein composed of human interleukin-4 and Pseudomonas exotoxin Cellular Immunology 1994 154 2 369 379 (Pubitemid 24115139)
    • (1994) Cellular Immunology , vol.154 , Issue.2 , pp. 369-379
    • Puri, R.K.1
  • 71
    • 0028067301 scopus 로고
    • Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein
    • Puri R. K., Leland P., Kreitman R. J., Pastan I., Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein International Journal of Cancer 1994 58 4 574 581 (Pubitemid 24268102)
    • (1994) International Journal of Cancer , vol.58 , Issue.4 , pp. 574-581
    • Puri, R.K.1    Leland, P.2    Kreitman, R.J.3    Pastan, I.4
  • 73
    • 0029135360 scopus 로고
    • Increased antitumor activity of a circularly permuted interleukin 4-toxin in mice with interleukin 4 receptor-bearing human carcinoma
    • Kreitman R. J., Puri R. K., Pastan I., Increased antitumor activity of a circularly permuted interleukin 4-toxin in mice with interleukin 4 receptor-bearing human carcinoma Cancer Research 1995 55 15 3357 3363
    • (1995) Cancer Research , vol.55 , Issue.15 , pp. 3357-3363
    • Kreitman, R.J.1    Puri, R.K.2    Pastan, I.3
  • 74
    • 0035890415 scopus 로고    scopus 로고
    • In situ expression of interleukin-4 (IL-4) receptors in human brain tumors and cytotoxicity of a recombinant IL-4 cytotoxin in primary glioblastoma cell cultures
    • Joshi B. H., Leland P., Asher A., Prayson R. A., Varricchio F., Puri R. K., In situ expression of interleukin-4 (IL-4) receptors in human brain tumors and cytotoxicity of a recombinant IL-4 cytotoxin in primary glioblastoma cell cultures Cancer Research 2001 61 22 8058 8061 (Pubitemid 33091589)
    • (2001) Cancer Research , vol.61 , Issue.22 , pp. 8058-8061
    • Joshi, B.H.1    Leland, P.2    Asher, A.3    Prayson, R.A.4    Varricchio, F.5    Puri, R.K.6
  • 75
    • 0029751129 scopus 로고    scopus 로고
    • Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma
    • Puri R. K., Hoon D. S., Leland P., Snoy P., Rand R. W., Pastan I., Kreitman R. J., Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma Cancer Research 1996 56 24 5631 5637 (Pubitemid 26422165)
    • (1996) Cancer Research , vol.56 , Issue.24 , pp. 5631-5637
    • Puri, R.K.1    Hoon, D.S.2    Leland, P.3    Snoy, P.4    Rand, R.W.5    Pastan, I.6    Kreitman, R.J.7
  • 76
    • 0032529436 scopus 로고    scopus 로고
    • Complete regression of established human glioblastoma tumor xenograft by interleukin-4 toxin therapy
    • Husain S. R., Behari N., Kreitman R. J., Pastan I., Puri R. K., Complete regression of established human glioblastoma tumor xenograft by interleukin-4 toxin therapy Cancer Research 1998 58 16 3649 3653 (Pubitemid 28376564)
    • (1998) Cancer Research , vol.58 , Issue.16 , pp. 3649-3653
    • Husain, S.R.1    Behari, N.2    Kreitman, R.J.3    Pastan, I.4    Puri, R.K.5
  • 77
    • 33747204065 scopus 로고    scopus 로고
    • The IL-4 and IL-13 pseudomonas exotoxins: New hope for brain tumor therapy
    • Shimamura T., Husain S. R., Puri R. K., The IL-4 and IL-13 pseudomonas exotoxins: new hope for brain tumor therapy Neurosurgical Focus 2006 20 4 E11
    • (2006) Neurosurgical Focus , vol.20 , Issue.4 , pp. 11
    • Shimamura, T.1    Husain, S.R.2    Puri, R.K.3
  • 79
    • 4143080435 scopus 로고    scopus 로고
    • Analysis of interleukin-13 receptor α2 expression in human pediatric brain tumors
    • DOI 10.1002/cncr.20470
    • Kawakami M., Kawakami K., Takahashi S., Abe M., Puri R. K., Analysis of interleukin-13 receptor 2 expression in human pediatric brain tumors Cancer 2004 101 5 1036 1042 (Pubitemid 39100438)
    • (2004) Cancer , vol.101 , Issue.5 , pp. 1036-1042
    • Kawakami, M.1    Kawakami, K.2    Takahashi, S.3    Abe, M.4    Puri, R.K.5
  • 80
    • 0028859363 scopus 로고
    • Human glioma cells overexpress receptors for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin
    • Debinski W., Obiri N. I., Powers S. K., Pastan I., Puri R. K., Human glioma cells overexpress receptors for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin Clinical Cancer Research 1995 1 11 1253 1258
    • (1995) Clinical Cancer Research , vol.1 , Issue.11 , pp. 1253-1258
    • Debinski, W.1    Obiri, N.I.2    Powers, S.K.3    Pastan, I.4    Puri, R.K.5
  • 81
    • 0031029303 scopus 로고    scopus 로고
    • Receptor for interleukin 13 on AIDS-associated Kaposi's sarcoma cells serves as a new target for a potent Pseudomonas exotoxin-based chimeric toxin protein
    • Husain S. R., Obiri N. I., Gill P., Zheng T., Pastan I., Debinski W., Puri R. K., Receptor for interleukin 13 on AIDS-associated Kaposi's sarcoma cells serves as a new target for a potent Pseudomonas exotoxin-based chimeric toxin protein Clinical Cancer Research 1997 3 2 151 156 (Pubitemid 27107288)
    • (1997) Clinical Cancer Research , vol.3 , Issue.2 , pp. 151-156
    • Husain, S.R.1    Obiri, N.I.2    Gill, P.3    Zheng, T.4    Pastan, I.5    Debinski, W.6    Puri, R.K.7
  • 82
    • 0042338458 scopus 로고    scopus 로고
    • Identification and characterization of interleukin-13 receptor in human medulloblastoma and targeting these receptors with interleukin-13-pseudomonas exotoxin fusion protein
    • Joshi B. H., Leland P., Puri R. K., Identification and characterization of interleukin-13 receptor in human medulloblastoma and targeting these receptors with interleukin-13-pseudomonas exotoxin fusion protein Croatian Medical Journal 2003 44 4 455 462 (Pubitemid 37092805)
    • (2003) Croatian Medical Journal , vol.44 , Issue.4 , pp. 455-462
    • Joshi, B.H.1    Leland, P.2    Puri, R.K.3
  • 83
    • 0035881289 scopus 로고    scopus 로고
    • Interleukin-13 receptor-targeted cancer therapy in an immunodeficient animal model of human head and neck cancer
    • Kawakami K., Kawakami M., Joshi B. H., Puri R. K., Interleukin-13 receptor-targeted cancer therapy in an immunodeficient animal model of human head and neck cancer Cancer Research 2001 61 16 6194 6200 (Pubitemid 32762557)
    • (2001) Cancer Research , vol.61 , Issue.16 , pp. 6194-6200
    • Kawakami, K.1    Kawakami, M.2    Joshi, B.H.3    Puri, R.K.4
  • 84
    • 0032901749 scopus 로고    scopus 로고
    • Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas
    • Debinski W., Gibo D. M., Hulet S. W., Connor J. R., Gillespie G. Y., Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas Clinical Cancer Research 1999 5 5 985 990 (Pubitemid 29233211)
    • (1999) Clinical Cancer Research , vol.5 , Issue.5 , pp. 985-990
    • Debinski, W.1    Gibo, D.M.2    Hulet, S.W.3    Connor, J.R.4    Gillespie, G.Y.5
  • 85
    • 0036268469 scopus 로고    scopus 로고
    • Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice
    • Li C., Hall W. A., Jin N., Todhunter D. A., Panoskaltsis-Mortari A., Vallera D. A., Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice Protein Engineering 2002 15 5 419 427 (Pubitemid 34601734)
    • (2002) Protein Engineering , vol.15 , Issue.5 , pp. 419-427
    • Li, C.1    Hall, W.A.2    Jin, N.3    Todhunter, D.A.4    Panoskaltsis-Mortari, A.5    Vallera, D.A.6
  • 87
    • 49849106612 scopus 로고    scopus 로고
    • Targeting IL-13RA2-positive cancer with a novel recombinant immunotoxin composed of a single-chain antibody and mutated Pseudomonas exotoxin
    • Kioi M., Seetharam S., Puri R. K., Targeting IL-13RA2-positive cancer with a novel recombinant immunotoxin composed of a single-chain antibody and mutated Pseudomonas exotoxin Molecular Cancer Therapeutics 2008 7 6 1579 1587
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.6 , pp. 1579-1587
    • Kioi, M.1    Seetharam, S.2    Puri, R.K.3
  • 88
    • 34548555781 scopus 로고    scopus 로고
    • Expression of interleukin-13 receptor α2 in glioblastoma multiforme: Implications for targeted therapies
    • DOI 10.1158/0008-5472.CAN-07-1493
    • Jarboe J. S., Johnson K. R., Choi Y., Lonser R. R., Park J. K., Expression of interleukin-13 receptor 2 in glioblastoma multiforme: implications for targeted therapies Cancer Research 2007 67 17 7983 7986 (Pubitemid 47395129)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 7983-7986
    • Jarboe, J.S.1    Johnson, K.R.2    Choi, Y.3    Lonser, R.R.4    Park, J.K.5
  • 89
    • 0021013896 scopus 로고
    • Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells
    • Massague J., Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells Journal of Biological Chemistry 1983 258 22 13614 13620 (Pubitemid 14211998)
    • (1983) Journal of Biological Chemistry , vol.258 , Issue.22 , pp. 13614-13620
    • Massague, J.1
  • 90
    • 0020405987 scopus 로고
    • Transforming growth factor and epidermal growth factor stimulate the phosphorylation of a synthetic, tyrosine-containing peptide in a similar manner
    • Pike L. J., Marquardt H., Todaro G. J., Transforming growth factor and epidermal growth factor stimulate the phosphorylation of a synthetic, tyrosine-containing peptide in a similar manner Journal of Biological Chemistry 1982 257 24 14628 14631 (Pubitemid 13159556)
    • (1982) Journal of Biological Chemistry , vol.257 , Issue.24 , pp. 14628-14631
    • Pike, L.J.1    Marquardt, H.2    Todaro, G.J.3
  • 91
    • 0021752924 scopus 로고
    • Human transforming growth factor-α: Precursor structure and expression in E. coli
    • Derynck R., Roberts A. B., Winkler M. E., Chen E. Y., Goeddel D. V., Human transforming growth factor- : precursor structure and expression in E. coli Cell 1984 38 1 287 297 (Pubitemid 15216556)
    • (1984) Cell , vol.38 , Issue.1 , pp. 287-297
    • Derynck, R.1    Roberts, A.B.2    Winkler, M.E.3
  • 93
    • 0019332971 scopus 로고
    • Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes
    • Ushiro H., Cohen S., Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes Journal of Biological Chemistry 1980 255 18 8363 8365
    • (1980) Journal of Biological Chemistry , vol.255 , Issue.18 , pp. 8363-8365
    • Ushiro, H.1    Cohen, S.2
  • 94
    • 0026571910 scopus 로고
    • The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: A review on 5232 patients
    • Klijn J. G. M., Berns P. M. J. J., Schmitz P. I. M., Foekens J. A., The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: a review on 5232 patients Endocrine Reviews 1992 13 1 3 17
    • (1992) Endocrine Reviews , vol.13 , Issue.1 , pp. 3-17
    • Klijn, J.G.M.1    Berns, P.M.J.J.2    Schmitz, P.I.M.3    Foekens, J.A.4
  • 95
    • 0027170357 scopus 로고
    • Evidence for a role of EGF receptor in the progression of human lung carcinoma
    • Pavelic K., Banjac Z., Pavelic J., Spaventi S., Evidence for a role of EGF receptor in the progression of human lung carcinoma Anticancer Research 1993 13 4 1133 1137 (Pubitemid 23247476)
    • (1993) Anticancer Research , vol.13 , Issue.4 , pp. 1133-1137
    • Pavelic, K.1    Banjac, Z.2    Pavelic, J.3    Spaventi, S.4
  • 96
    • 0029831041 scopus 로고    scopus 로고
    • Quantitative immunohistochemical analysis of transforming growth factor- α and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck
    • DOI 10.1002/(SICI)1097-0142(19960915)78:6<1284::AID-CNCR17>3.0. CO;2-X
    • Rubin Grandis J., Melhem M. F., Barnes E. L., Tweardy D. J., Quantitative immunohistochemical analysis of transforming growth factor- and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck Cancer 1996 78 6 1284 1292 (Pubitemid 26303896)
    • (1996) Cancer , vol.78 , Issue.6 , pp. 1284-1292
    • Grandis, J.R.1    Melhem, M.F.2    Barnes, E.L.3    Tweardy, D.J.4
  • 97
    • 0028168271 scopus 로고
    • Prognostic value of c-erbB-2 and epidermal growth factor receptor in stage A1 (T1a) prostatic adenocarcinoma
    • Fox S. B., Persad R. A., Coleman N., Day C. A., Silcocks P. B., Collins C. C., Prognostic value of c-erbB-2 and epidermal growth factor receptor in stage A1 (T1a) prostatic adenocarcinoma The British Journal of Urology 1994 74 2 214 220
    • (1994) The British Journal of Urology , vol.74 , Issue.2 , pp. 214-220
    • Fox, S.B.1    Persad, R.A.2    Coleman, N.3    Day, C.A.4    Silcocks, P.B.5    Collins, C.C.6
  • 98
    • 0034782994 scopus 로고    scopus 로고
    • Expression profiles of ErbB family receptors and prognosis in primary transitional cell carcinoma of the urinary bladder
    • Chow N. H., Chan S. H., Tzai T. S., Ho C. L., Liu H. S., Expression profiles of ErbB family receptors and prognosis in primary transitional cell carcinoma of the urinary bladder Clinical Cancer Research 2001 7 7 1957 1962
    • (2001) Clinical Cancer Research , vol.7 , Issue.7 , pp. 1957-1962
    • Chow, N.H.1    Chan, S.H.2    Tzai, T.S.3    Ho, C.L.4    Liu, H.S.5
  • 99
    • 0023874489 scopus 로고
    • Expression of epidermal growth factor receptor in human gastric and colonic carcinomas
    • Yasui W., Sumiyoshi H., Hata J., Kameda T., Ochiai A., Ito H., Tahara E., Expression of epidermal growth factor receptor in human gastric and colonic carcinomas Cancer Research 1988 48 1 137 141 (Pubitemid 18030342)
    • (1988) Cancer Research , vol.48 , Issue.1 , pp. 137-141
    • Yasui, W.1    Sumiyoshi, H.2    Hata, J.3    Kameda, T.4    Ochiai, A.5    Ito, H.6    Tahara, E.7
  • 102
    • 0021363560 scopus 로고
    • Expression of epidermal growth factor receptors in human brain tumors
    • Libermann T. A., Razon N., Bartal A. D., Expression of epidermal growth factor receptors in human brain tumors Cancer Research 1984 44 2 753 760 (Pubitemid 14184614)
    • (1984) Cancer Research , vol.44 , Issue.2 , pp. 753-760
    • Libermann, T.A.1    Razon, N.2    Bartal, A.D.3
  • 103
    • 0021932240 scopus 로고
    • Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
    • DOI 10.1038/313144a0
    • Libermann T. A., Nusbaum H. R., Razon N., Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin Nature 1985 313 5998 144 147 (Pubitemid 15192341)
    • (1985) Nature , vol.313 , Issue.5998 , pp. 144-147
    • Libermann, T.A.1    Nusbaum, H.R.2    Razon, N.3
  • 104
    • 0342627798 scopus 로고
    • Amplified cellular oncogenes in neoplasms of the human central nervous system
    • Fuller G. N., Bigner S. H., Amplified cellular oncogenes in neoplasms of the human central nervous system Mutation Research 1992 276 3 299 306
    • (1992) Mutation Research , vol.276 , Issue.3 , pp. 299-306
    • Fuller, G.N.1    Bigner, S.H.2
  • 106
    • 0033392005 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
    • DOI 10.1023/A:1006384521198
    • Huang S. M., Harari P. M., Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results Investigational New Drugs 1999 17 3 259 269 (Pubitemid 30037958)
    • (1999) Investigational New Drugs , vol.17 , Issue.3 , pp. 259-269
    • Huang, S.-M.1    Harari, P.M.2
  • 107
    • 0027421951 scopus 로고
    • Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells
    • Kunwar S., Pai L. H., Pastan I., Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells Journal of Neurosurgery 1993 79 4 569 576 (Pubitemid 23289815)
    • (1993) Journal of Neurosurgery , vol.79 , Issue.4 , pp. 569-576
    • Kunwar, S.1    Pai, L.H.2    Pastan, I.3
  • 108
    • 0028179159 scopus 로고
    • Transforming growth factor- -Pseudomonas exotoxin fusion protein (TGF- -PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice
    • Phillips P. C., Levow C., Catterall M., Colvin O. M., Pastan I., Brem H., Transforming growth factor- -Pseudomonas exotoxin fusion protein (TGF- -PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice Cancer Research 1994 54 4 1008 1015
    • (1994) Cancer Research , vol.54 , Issue.4 , pp. 1008-1015
    • Phillips, P.C.1    Levow, C.2    Catterall, M.3    Colvin, O.M.4    Pastan, I.5    Brem, H.6
  • 109
    • 0037138431 scopus 로고    scopus 로고
    • Intratumoral immunotoxin treatment of human malignant brain tumors in immunodeficient animals
    • DOI 10.1002/ijc.10137
    • Engebraaten O., Hjortland G. O., Juell S., Hirschberg H., Fodstad., Intratumoral immunotoxin treatment of human malignant brain tumors in immunodeficient animals International Journal of Cancer 2002 97 6 846 852 (Pubitemid 34106343)
    • (2002) International Journal of Cancer , vol.97 , Issue.6 , pp. 846-852
    • Engebraaten, O.1    Hjortland, G.O.2    Juell, S.3    Hirschberg, H.4    Fodstad, O.5
  • 110
    • 0037447150 scopus 로고    scopus 로고
    • A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells
    • Liu T. F., Cohen K. A., Ramage J. G., Willingham M. C., Thorburn A. M., Frankel A. E., A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells Cancer Research 2003 63 8 1834 1837 (Pubitemid 36460845)
    • (2003) Cancer Research , vol.63 , Issue.8 , pp. 1834-1837
    • Liu, T.F.1    Cohen, K.A.2    Ramage, J.G.3    Willingham, M.C.4    Thorburn, A.M.5    Frankel, A.E.6
  • 111
    • 7144261725 scopus 로고    scopus 로고
    • The class III variant of the epidermal growth factor receptor (EGFRvIII): Characterization and utilization as an immunotherapeutic target
    • Wikstrand C. J., Reist C. J., Archer G. E., Zalutsky M. R., Bigner D. D., The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target Journal of NeuroVirology 1998 4 2 148 158 (Pubitemid 28167490)
    • (1998) Journal of NeuroVirology , vol.4 , Issue.2 , pp. 148-158
    • Wikstrand, G.J.1    Reist, C.J.2    Archer, G.E.3    Zalutsky, M.R.4    Bigner, D.D.5
  • 117
    • 0032510679 scopus 로고    scopus 로고
    • Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases
    • Nagane M., Levitzki A., Gazit A., Cavenee W. K., Huang H. J. S., Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases Proceedings of the National Academy of Sciences of the United States of America 1998 95 10 5724 5729
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.10 , pp. 5724-5729
    • Nagane, M.1    Levitzki, A.2    Gazit, A.3    Cavenee, W.K.4    Huang, H.J.S.5
  • 118
    • 0029057002 scopus 로고
    • Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors
    • Lorimer I. A. J., Wikstrand C. J., Batra S. K., Bigner D. D., Pastan I., Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors Clinical Cancer Research 1995 1 8 859 864
    • (1995) Clinical Cancer Research , vol.1 , Issue.8 , pp. 859-864
    • Lorimer, I.A.J.1    Wikstrand, C.J.2    Batra, S.K.3    Bigner, D.D.4    Pastan, I.5
  • 121
    • 0033927216 scopus 로고    scopus 로고
    • Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display
    • Beers R., Chowdhury P., Bigner D., Pastan I., Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display Clinical Cancer Research 2000 6 7 2835 2843 (Pubitemid 30482125)
    • (2000) Clinical Cancer Research , vol.6 , Issue.7 , pp. 2835-2843
    • Beers, R.1    Chowdhury, P.2    Bigner, D.3    Pastan, I.4
  • 125
    • 79955406259 scopus 로고    scopus 로고
    • Affinity-matured anti-glycoprotein nmb recombinant immunotoxins targeting malignant gliomas and melanomas
    • Kuan C.T., Wakiya K., Keir S.T., Affinity-matured anti-glycoprotein nmb recombinant immunotoxins targeting malignant gliomas and melanomas International Journal of Cancer 2011 129 111 121
    • (2011) International Journal of Cancer , vol.129 , pp. 111-121
    • Kuan, C.T.1    Wakiya, K.2    Keir, S.T.3
  • 127
    • 0026425579 scopus 로고
    • Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells
    • Schrappe M., Klier F. G., Spiro R. C., Waltz T. A., Reisfeld R. A., Gladson C. L., Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells Cancer Research 1991 51 18 4986 4993
    • (1991) Cancer Research , vol.51 , Issue.18 , pp. 4986-4993
    • Schrappe, M.1    Klier, F.G.2    Spiro, R.C.3    Waltz, T.A.4    Reisfeld, R.A.5    Gladson, C.L.6
  • 128
    • 0942287653 scopus 로고    scopus 로고
    • Immunotoxin treatment targeted to the high-molecular-weight melanoma-associated antigen prolonging the survival of immunodeficient rats with invasive intracranial human glioblastoma multiforme
    • Hjortland G. O., Garman-Vik S. S., Juell S., Olsen. E., Hirschberg H., Fodstad., Engebraaten O., Immunotoxin treatment targeted to the high-molecular-weight melanoma-associated antigen prolonging the survival of immunodeficient rats with invasive intracranial human glioblastoma multiforme Journal of Neurosurgery 2004 100 2 320 327 (Pubitemid 38140237)
    • (2004) Journal of Neurosurgery , vol.100 , Issue.2 , pp. 320-327
    • Hjortland, G.O.1    Garman-Vik, S.S.2    Juell, S.3    Olsen, O.E.4    Hirschberg, H.5    Fodstad, O.6    Engebraaten, O.7
  • 129
    • 0018868096 scopus 로고
    • Common human melanoma-associated antigen(s) detected by monoclonal antibodies
    • Carrel S., Accolla R. S., Carmagnola A. L., Mach J. P., Common human melanoma-associated antigen(s) detected by monoclonal antibodies Cancer Research 1980 40 7 2523 2528 (Pubitemid 10082277)
    • (1980) Cancer Research , vol.40 , Issue.7 , pp. 2523-2528
    • Carrel, S.1    Accolla, R.S.2    Carmagnola, A.L.3    Mach, J.P.4
  • 131
    • 0029031343 scopus 로고
    • Phase i studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F(ab')2a preliminary report
    • Bigner D. D., Brown M., Coleman R. E., Friedman A. H., Friedman H. S., McLendon R. E., Bigner S. H., Zhao X. G., Wikstrand C. J., Pegram C. N., Kerby T., Zalutsky M. R., Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F(ab')2a preliminary report Journal of Neuro-Oncology 1995 24 1 109 122
    • (1995) Journal of Neuro-Oncology , vol.24 , Issue.1 , pp. 109-122
    • Bigner, D.D.1    Brown, M.2    Coleman, R.E.3    Friedman, A.H.4    Friedman, H.S.5    McLendon, R.E.6    Bigner, S.H.7    Zhao, X.G.8    Wikstrand, C.J.9    Pegram, C.N.10    Kerby, T.11    Zalutsky, M.R.12
  • 134
    • 0031559401 scopus 로고    scopus 로고
    • Unified nomenclature for eph family receptors and their ligands, the ephrins
    • Eph Nomenclature Committee
    • Eph Nomenclature Committee, Unified nomenclature for eph family receptors and their ligands, the ephrins Cell 1997 90 403 404
    • (1997) Cell , vol.90 , pp. 403-404
  • 135
    • 0036303033 scopus 로고    scopus 로고
    • Mechanisms and functions of Eph and ephrin signalling
    • DOI 10.1038/nrm856
    • Kullander K., Klein R., Mechanisms and functions of Eph and ephrin signalling Nature Reviews Molecular Cell Biology 2002 3 7 475 486 (Pubitemid 34733429)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.7 , pp. 475-486
    • Kullander, K.1    Klein, R.2
  • 136
    • 37549047649 scopus 로고    scopus 로고
    • A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor-expressing tumor cells
    • Wykosky J., Gibo D. M., Debinski W., A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor-expressing tumor cells Molecular Cancer Therapeutics 2007 6 12 3208 3218
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.12 , pp. 3208-3218
    • Wykosky, J.1    Gibo, D.M.2    Debinski, W.3
  • 137
    • 27644466229 scopus 로고    scopus 로고
    • EphA2 as a novel molecular marker and target in glioblastoma multiforme
    • DOI 10.1158/1541-7786.MCR-05-0056
    • Wykosky J., Gibo D. M., Stanton C., Debinski W., EphA2 as a novel molecular marker and target in glioblastoma multiforme Molecular Cancer Research 2005 3 10 541 551 (Pubitemid 41567273)
    • (2005) Molecular Cancer Research , vol.3 , Issue.10 , pp. 541-551
    • Wykosky, J.1    Gibo, D.M.2    Stanton, C.3    Debinski, W.4
  • 139
    • 0037123350 scopus 로고    scopus 로고
    • Targeting Urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT
    • Vallera D. A., Li C., Jin N., Panoskaltsis-Mortari A., Hall W. A., Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT Journal of the National Cancer Institute 2002 94 8 597 606 (Pubitemid 34498647)
    • (2002) Journal of the National Cancer Institute , vol.94 , Issue.8 , pp. 597-606
    • Vallera, D.A.1    Li, C.2    Jin, N.3    Panoskaltsis-Mortari, A.4    Hall, W.A.5
  • 140
    • 38649092392 scopus 로고    scopus 로고
    • Anti-glioblastoma effect of a recombinant bispecific cytotoxin cotargeting human IL-13 and EGF receptors in a mouse xenograft model
    • Stish B. J., Oh S., Vallera D. A., Anti-glioblastoma effect of a recombinant bispecific cytotoxin cotargeting human IL-13 and EGF receptors in a mouse xenograft model Journal of Neuro-Oncology 2008 87 1 51 61
    • (2008) Journal of Neuro-Oncology , vol.87 , Issue.1 , pp. 51-61
    • Stish, B.J.1    Oh, S.2    Vallera, D.A.3
  • 141
    • 79957997583 scopus 로고    scopus 로고
    • Evaluation of a bispecific biological drug designed to simultaneously target glioblastoma and its neovasculature in the brain: Laboratory investigation
    • Oh S., Tsai A. K., Ohlfest J. R., Panoskaltsis-Mortari A., Vallera D. A., Evaluation of a bispecific biological drug designed to simultaneously target glioblastoma and its neovasculature in the brain: laboratory investigation Journal of Neurosurgery 2011 114 6 1662 1671
    • (2011) Journal of Neurosurgery , vol.114 , Issue.6 , pp. 1662-1671
    • Oh, S.1    Tsai, A.K.2    Ohlfest, J.R.3    Panoskaltsis-Mortari, A.4    Vallera, D.A.5
  • 142
    • 1842665126 scopus 로고    scopus 로고
    • A bispecific immunotoxin (DTAT13) targeting human IL-13 receptor (IL-13R) and urokinase-type plasminogen activator receptor (uPAR) in a mouse xenograft model
    • DOI 10.1093/protein/gzh023
    • Todhunter D. A., Hall W. A., Rustamzadeh E., Shu Y., Doumbia S. O., Vallera D. A., A bispecific immunotoxin (DTAT13) targeting human IL-13 receptor (IL-13R) and urokinase-type plasminogen activator receptor (uPAR) in a mouse xenograft model Protein Engineering, Design and Selection 2004 17 2 157 164 (Pubitemid 38477742)
    • (2004) Protein Engineering, Design and Selection , vol.17 , Issue.2 , pp. 157-164
    • Todhunter, D.A.1    Hall, W.A.2    Rustamzadeh, E.3    Shu, Y.4    Doumbia, S.O.5    Vallera, D.A.6
  • 143
    • 33747174300 scopus 로고    scopus 로고
    • Convection-enhanced delivery of immunotoxins and radioisotopes for treatment of malignant gliomas
    • Vandergrift W. A., Patel S. J., Nicholas J. S., Varma A. K., Convection-enhanced delivery of immunotoxins and radioisotopes for treatment of malignant gliomas Neurosurgical Focus 2006 20 4 E13
    • (2006) Neurosurgical Focus , vol.20 , Issue.4 , pp. 13
    • Vandergrift, W.A.1    Patel, S.J.2    Nicholas, J.S.3    Varma, A.K.4
  • 145
    • 14844341937 scopus 로고    scopus 로고
    • Current status of therapy of solid tumors: Brain tumor therapy
    • Zalutsky M. R., Current status of therapy of solid tumors: brain tumor therapy Journal of Nuclear Medicine 2005 46 1 151S 156S (Pubitemid 47619030)
    • (2005) Journal of Nuclear Medicine , vol.46 , Issue.1 SUPPL.
    • Zalutsky, M.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.