Local convection enhanced, delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma

Acta Neurochirurgica, Supplementum

Volumn , Issue 88, 2003, Pages 93-103

  Weber, F W ^a   Floeth, F ^a   Asher, A ^b   Bucholz, R ^c   Berger, M ^d   Prados, M ^d   Chang, S ^d   Bruce, J ^e   Hall, W ^f   Rainov, N G ^g   Westphal, M ^h   Warnick, R E ⁱ   Rand, R W ^j   Rommel, F ^k   Pan, H ^k   Hingorani, V N ^k   Puri, R K ^l  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b CAROLINA NEUROSURGERY AND SPINE ASSOCIATES   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f UNIVERSITY OF MINNESOTA   (United States)

^g MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^h UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

ⁱ UNIVERSITY OF CINCINNATI   (United States)

^j JOHN WAYNE CANCER INSTITUTE   (United States)

^k NEUROCRINE BIOSCIENCES INC   (United States)

^l CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

more..

Author keywords

Astrocytoma; Glioblastoma multiforme; Immunotoxin; Intratumoral therapy; Malignant glioma

Indexed keywords

BACTERIAL TOXIN; EXOTOXIN; IMMUNOTOXIN; INTERLEUKIN 4; INTERLEUKIN 4 PSEUDOMONAS EXOTOXIN; INTERLEUKIN-4-PSEUDOMONAS EXOTOXIN;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; ASTROCYTOMA; BRAIN TUMOR; CLINICAL TRIAL; COMPARATIVE STUDY; DOSE RESPONSE; FEMALE; GLIOBLASTOMA; HUMAN; INTRALESIONAL DRUG ADMINISTRATION; MALE; MIDDLE AGED; MULTICENTER STUDY; MULTIMODALITY CANCER THERAPY; NUCLEAR MAGNETIC RESONANCE IMAGING; PROSPECTIVE STUDY; STEREOTAXIC SURGERY; TUMOR RECURRENCE;

ADULT; AGED; ASTROCYTOMA; BACTERIAL TOXINS; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, DRUG; EXOTOXINS; FEMALE; GLIOBLASTOMA; HUMANS; IMMUNOTOXINS; INFUSIONS, INTRALESIONAL; INTERLEUKIN-4; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROSPECTIVE STUDIES; STEREOTAXIC TECHNIQUES; SUPRATENTORIAL NEOPLASMS;

EID: 1542787924     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6090-9_15     Document Type: Article

References (25)

1. Bobo RH, Laske DW, Akbasak A et al (1994) Convection- enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci USA 91: 2076-2080
2. Brem H, Piantadosi S, Burger PC et al(1995) Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group. Lancet 345: 1008-1012
3. DeAngelis LM (2001) Brain tumors. N Engl J Med 344: 114-124
4. Di Massimo AM, Di Loreto M, Pacilli A et al (1997) Im-munoconjugates made of an anti-EGF receptor monoclonal antibody and type 1 ribosome-inactivating proteins from Saponaria ocymoides or Vaccaria pyramidata. Br J Cancer 75:822- 828
5. Frankel AE, Kreitman RJ, Sausville EA (2000) Targeted toxins. Clin Cancer Res 6:326-334
6. Guyotat J, Signoreili F, Frappaz D, et al (2000) Is reoperation for recurrence of glioblastoma justified? Oncol Rep 7(4): 899-904.
7. Husain SR, Behari N, Kreitman RJ et al (1998) Complete regression of established human glioblastoma tumor xenograft by interleukin-4 toxin therapy. Cancer Res 58: 3649-3653
8. Husain SR, Joshi BH, Puri RK (2001) Interleukin-13 receptor as a unique target for anti-glioblastoma therapy. Int J Cancer 92: 168-175
9. Jin W, Bi W, Huang ES et al (1999) Glioblastoma cell-specific expression of fibroblast growth factor receptor-1 beta requires an intronic repressor of RNA splicing. Cancer Res 59: 316-519
10. Joshi BH, Leiand P, Asher A et al (2001) In situ expression of interleukin-4 receptors in human brain tumors and cytotoxicity of a recombinant interleukin-4 (IL-4) cytotoxin in primary glioblastoma cell cultures. Cancer Res 61: 8058-8061
11. Joshi BH, Plautz GE, Puri RK (2001) Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas. Cancer Res 60: 1168-1172
12. Kreitman RJ, Puri RK, Pastan I (1994) A circularly permuted recombinant interleukin 4 toxin with increased activity. Proc Natl Acad Sci USA 91: 6889-6893
13. Kreitman RJ, Puri RK, Pastan I (1995) Increased antitumor activity of a circularly permuted interleukin 4-toxin in mice with interleukin 4 receptor-bearing human carcinoma. Cancer Res 55: 3357-3363
14. Kurpad SN, Zhao XG, Wikstrand CJ et al (1995) Tumor antigens in astrocytic gliomas. Glia 15: 244-256
15. Laske DW, Ilercil O, Akbasak A et al (1994) Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice. J Neurosurg 80: 520-526
16. Laske DW, Youle RJ, Oldfield EH (1997) Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors. Nat Med 3: 1362-1368
17. LeMaistre CF, Meneghetti C, Howes L et al (1994) Targeting the EGF receptor in breast cancer treatment. Breast Cancer Res Treat 32:97-103
18. Lieberman DM, Laske DW, Morrison PF et al (1995) Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion. J Neurosurg 82: 1021-1029
19. Liu H, Prayson RA, Estes ML et al (2000) In vivo expression of the interleukin 4 receptor alpha by astrocytes in epilepsy cerebral cortex. Cytokine 12: 1656-1661
20. Puri RK, Hoon DS, Leiand P et al (1996) Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma. Cancer Res 56: 5631-5637
21. Puri RK, Leiand P, Kreitman RJ et al(1994) Human neurological cancer cells Express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein. Int J Cancer 58: 574-581
22. Puri RK, Leiand P, Obiri NI et al (1996) An improved circularly permuted interleukin 4-toxin is highly cytotoxic to human renal cell carcinoma cells. Introduction of gamma c chain in RCC cells does not improve sensitivity. Cell Immunol 171: 80-86
23. Rahaman SO, Shrama P, Harbor PC et al (2002) Il-13Ralpha2, a decoy receptor for IL-13 acts as an inhibitor of IL-4-dependent signal transudation in glioblastoma cells. Cancer Res 62: 1103-1109
24. Rand RW, Kreitman RJ, Patronas N et al (2000) Intratumoral administration of recombinant circularly permuted interleukin- 4-Pseudomonas exotoxin in patients with high-grade glioma. Clin Cancer Res 6: 2157-2165
25. Surawicz TS et al (1999) Descriptive epidemiology of primary brain and CNS tumors: results from the Central Brain Tumor Registry of the United States, 1990-1994. Neurooncology 1: 14-25