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Volumn 6, Issue 7, 2000, Pages 2835-2843

Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOTOXIN;

EID: 0033927216     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (78)

References (28)
  • 1
    • 0029857998 scopus 로고    scopus 로고
    • Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: Targeting with a single chain antibody variable domain isolated by phage display
    • Lorimer, I. A. J., Keppler-Hafkemeyer, A., Beers, R. A., Pegram, C. N., Bigner, D. D., and Pastan, I. Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display. Proc. Natl. Acad. Sci. USA, 93: 14815-14820, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14815-14820
    • Lorimer, I.A.J.1    Keppler-Hafkemeyer, A.2    Beers, R.A.3    Pegram, C.N.4    Bigner, D.D.5    Pastan, I.6
  • 2
    • 0029057002 scopus 로고
    • Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors
    • Lorimer, I. A. J., Wikstrand, C. J., Batra, S. K, Bigner, D. D., and Pastan, I. Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors. Clin. Cancer Res., 1: 859-864, 1995.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 859-864
    • Lorimer, I.A.J.1    Wikstrand, C.J.2    Batra, S.K.3    Bigner, D.D.4    Pastan, I.5
  • 6
    • 0023657391 scopus 로고
    • Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in Escherichia coli
    • Hwang, J., FitzGerald, D. J., Adhya, S., and Pastan, I. Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in Escherichia coli. Cell, 48: 129-136, 1987.
    • (1987) Cell , vol.48 , pp. 129-136
    • Hwang, J.1    FitzGerald, D.J.2    Adhya, S.3    Pastan, I.4
  • 9
    • 0031838498 scopus 로고    scopus 로고
    • Clinical trials with Pseudomonas exotoxin immunotoxins
    • Pai, L. H., and Pastan, I. Clinical trials with Pseudomonas exotoxin immunotoxins. Clin. Appl. Immunotoxins, 234: 83-96, 1998.
    • (1998) Clin. Appl. Immunotoxins , vol.234 , pp. 83-96
    • Pai, L.H.1    Pastan, I.2
  • 11
    • 0030200088 scopus 로고    scopus 로고
    • Selection and evolution of high-affinity human anti-viral antibodies
    • Barbas, C. F., and Burton, D. R. Selection and evolution of high-affinity human anti-viral antibodies. Trends Biotechnol., 14: 230-234, 1996.
    • (1996) Trends Biotechnol. , vol.14 , pp. 230-234
    • Barbas, C.F.1    Burton, D.R.2
  • 12
    • 0029564921 scopus 로고
    • CDR walking mutagenesis for the affinity maturation of a potent human anti-Hiv-1 antibody into the picomolar range
    • Yang, W. P., Green, K., Pinzsweeney, S., Briones, A. T., Burton, D. R., and Barbas, C. F. CDR walking mutagenesis for the affinity maturation of a potent human anti-Hiv-1 antibody into the picomolar range. J. Mol. Biol., 254: 392-403, 1995.
    • (1995) J. Mol. Biol. , vol.254 , pp. 392-403
    • Yang, W.P.1    Green, K.2    Pinzsweeney, S.3    Briones, A.T.4    Burton, D.R.5    Barbas, C.F.6
  • 13
    • 0005229135 scopus 로고    scopus 로고
    • Mimicking somatic hypermutation: Affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain
    • Low, N. M., Holliger, P., and Winter, G. Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain. J. Mol. Biol., 260: 359-368, 1996.
    • (1996) J. Mol. Biol. , vol.260 , pp. 359-368
    • Low, N.M.1    Holliger, P.2    Winter, G.3
  • 14
    • 0028926814 scopus 로고
    • Selection and application of human single-chain Fv antibody fragments from a semisynthetic phage antibody display library with designed CDR3 regions
    • Dekruif, J., Boel, E., and Logtenberg, T. Selection and application of human single-chain Fv antibody fragments from a semisynthetic phage antibody display library with designed CDR3 regions. J. Mol. Biol., 248: 97-105, 1995.
    • (1995) J. Mol. Biol. , vol.248 , pp. 97-105
    • Dekruif, J.1    Boel, E.2    Logtenberg, T.3
  • 15
    • 0032555478 scopus 로고    scopus 로고
    • Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel
    • Pini, A., Viti, F., Santucci, A., Carnemolla, B., Zardi, L., Neri, P., and Neri, D. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J. Biol. Chem., 273: 21769-21776, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21769-21776
    • Pini, A.1    Viti, F.2    Santucci, A.3    Carnemolla, B.4    Zardi, L.5    Neri, P.6    Neri, D.7
  • 17
    • 0033056238 scopus 로고    scopus 로고
    • Improving antibody affinity by mimicking somatic hypermutation in vitro
    • Chowdhury, P. S., and Pastan, I. Improving antibody affinity by mimicking somatic hypermutation in vitro. Nat. Biotechnol., 17: 568-572, 1999.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 568-572
    • Chowdhury, P.S.1    Pastan, I.2
  • 19
    • 0025226085 scopus 로고
    • Phage antibodies-filamentous phage displaying antibody variable domains
    • McCafferty, J., Griffiths, A. D., Winter, G., and Chiswell, D. J. Phage antibodies-filamentous phage displaying antibody variable domains. Nature (Lond.) 348: 552-554, 1990.
    • (1990) Nature (Lond.) , vol.348 , pp. 552-554
    • McCafferty, J.1    Griffiths, A.D.2    Winter, G.3    Chiswell, D.J.4
  • 20
    • 0025838021 scopus 로고
    • Assembly of combinatorial antibody libraries on phage surfaces. the gene-III site
    • Barbas, C. J., Kang, A. S., Lerner, R. A., and Benkovic, S. J. Assembly of combinatorial antibody libraries on phage surfaces. The gene-III site. Proc. Natl. Acad. Sci. USA, 88: 7978-7982, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7978-7982
    • Barbas, C.J.1    Kang, A.S.2    Lerner, R.A.3    Benkovic, S.J.4
  • 21
    • 0030580057 scopus 로고    scopus 로고
    • Antibody-antigen interactions: Contact analysis and binding site topography
    • MacCallum, R. M., Martin, A. C. R., and Thornton, J. M. Antibody-antigen interactions: contact analysis and binding site topography. J. Mol. Biol., 262: 732-745, 1996.
    • (1996) J. Mol. Biol. , vol.262 , pp. 732-745
    • MacCallum, R.M.1    Martin, A.C.R.2    Thornton, J.M.3
  • 23
    • 0029992777 scopus 로고    scopus 로고
    • The targeting of somatic hypermutation
    • Jolly, C. J. The targeting of somatic hypermutation. Semin. Immunol., 8: 159-168, 1996.
    • (1996) Semin. Immunol. , vol.8 , pp. 159-168
    • Jolly, C.J.1
  • 25
    • 0030450401 scopus 로고    scopus 로고
    • Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation
    • Goyenechea, B., and Milstein, C. Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation. Proc. Natl. Acad. Sci. USA, 93: 13979-13984, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13979-13984
    • Goyenechea, B.1    Milstein, C.2
  • 26
    • 0026792807 scopus 로고
    • A method for increasing the yield of properly folded recombinant fusion proteins-single-chain immunotoxins from renaturation of bacterial inclusion bodies
    • Buchner, J., Pastan, I., and Brinkmann, U. A method for increasing the yield of properly folded recombinant fusion proteins-single-chain immunotoxins from renaturation of bacterial inclusion bodies. Anal. Biochem., 205: 263-270, 1992.
    • (1992) Anal. Biochem. , vol.205 , pp. 263-270
    • Buchner, J.1    Pastan, I.2    Brinkmann, U.3
  • 27
    • 0026033387 scopus 로고
    • Barnase toxin: A new chimeric toxin composed of Pseudomonas exotoxin-a and barnase
    • Prior, T. I., FitzGerald, D. J., and Pastan, I. Barnase toxin: a new chimeric toxin composed of Pseudomonas exotoxin-A and barnase. Cell, 64: 1017-1023, 1991.
    • (1991) Cell , vol.64 , pp. 1017-1023
    • Prior, T.I.1    FitzGerald, D.J.2    Pastan, I.3
  • 28
    • 0033593356 scopus 로고    scopus 로고
    • Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire
    • de Wildt, R. M. T., Hoet, R. M. A., van Venrooij, W. J., Tomlinson, I. M., and Winter, G. Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. J. Mol. Biol., 285: 895-901, 1999.
    • (1999) J. Mol. Biol. , vol.285 , pp. 895-901
    • De Wildt, R.M.T.1    Hoet, R.M.A.2    Van Venrooij, W.J.3    Tomlinson, I.M.4    Winter, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.