Colocalization of gadolinium-diethylene triamine pentaacetic acid with high-molecular-weight molecules after intracerebral convection-enhanced delivery in humans

Neurosurgery

Volumn 69, Issue 3, 2011, Pages 668-676

  Sampson, John H ^a,b   Brady, Martin ^c   Raghavan, Raghu ^c   Mehta, Ankit I ^a   Friedman, Allan H ^a   Reardon, David A ^a,b   Petry, Neil A ^b   Barboriak, Daniel P ^b   Wong, Terence Z ^b   Zalutsky, Michael R ^b   Lally Goss, Denise ^a   Bigner, Darell D ^b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c Therataxis LLC   (United States)

Author keywords

Brain neoplasms; Convection; Drug delivery systems; Gadolinium DTPA; Iodine radioisotopes; Magnetic resonance imaging; Positron emission tomography

Indexed keywords

BEVACIZUMAB; GADOLINIUM PENTETATE; HUMAN SERUM ALBUMIN I 124; IMMUNOTOXIN; IRINOTECAN; RADIOPHARMACEUTICAL AGENT; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BRAIN RADIATION; CASE REPORT; CEREBROSPINAL FLUID; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONVECTION ENHANCED DELIVERY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG SAFETY; FLUID ATTENUATED INVERSION RECOVERY IMAGING; GLIOBLASTOMA; HUMAN; IMAGING SYSTEM; INTRACRANIAL PRESSURE; ISOTOPE LABELING; KARNOFSKY PERFORMANCE STATUS; MALE; MAXIMUM PLASMA CONCENTRATION; MAXIMUM TOLERATED DOSE; METHODOLOGY; MOLECULAR WEIGHT; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT SELECTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SUBARACHNOID SPACE;

ALGORITHMS; ASTROCYTOMA; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; CONTRAST MEDIA; CONVECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; GADOLINIUM DTPA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; SERUM ALBUMIN, RADIO-IODINATED; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 80051796008     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/NEU.0b013e3182181ba8     Document Type: Article

References (32)

1. Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci U S A. 1994;91(6):2076-2080.
2. Grossi PM, Ochiai H, Archer GE, et al. Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer. Clin Cancer Res. 2003;9(15):5514-5520.
3. Heimberger AB, Archer GE, McLendon RE, et al. Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats. Clin Cancer Res. 2000;6(10):4148-4153.
4. Kunwar S, Chang S, Westphal M, et al. Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma. Neuro Oncol. 2010;12(8):871-881.
5. Gill SS, Patel NK, Hotton GR, et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med. 2003;9(5):589-595.
6. Jarboe JS, Johnson KR, Choi Y, Lonser RR, Park JK. Expression of interleukin-13 receptor alpha2 in glioblastoma multiforme: Implications for targeted therapies. Cancer Res. 2007;67(17):7983-7986.
7. Sampson JH, Brady ML, Petry NA, et al. Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: Descriptive effects of target anatomy and catheter positioning. Neurosurgery. Feb 2007;60(2 suppl 1):ONS89-ONS98; discussion ONS98-ONS89.
8. Sampson JH, Archer G, Pedain C, et al. Poor drug distribution as a possible explanation for the results of the PRECISE trial. J Neurosurg. 2009;113(2): 301-309.
9. Sampson JH, Raghavan R, Brady ML, et al. Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions. Neuro Oncol. 2007;9(3):343-353.
10. Lonser RR, Walbridge S, Murray GJ, et al. Convection perfusion of glucocerebrosidase for neuronopathic Gaucher's disease. Ann Neurol. 2005;57(4):542-548.
11. Murad GJ,Walbridge S, Morrison PF, et al. Real-time, image-guided, convectionenhanced delivery of interleukin 13 bound to pseudomonas exotoxin. Clin Cancer Res. 2006;12(10):3145-3151.
12. Lonser RR, Schiffman R, Robison RA, et al. Image-guided, direct convective delivery of glucocerebrosidase for neuronopathic Gaucher disease. Neurology. 2007;68(4):254-261.
13. Song DK, Lonser RR. Convection-enhanced delivery for the treatment of pediatric neurologic disorders. J Child Neurol. 2008;23(10):1231-1237.
14. Saito R, Bringas JR, McKnight TR, et al. Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging. Cancer Res. 2004;64(7):2572-2579.
15. Sampson JH, Raghavan R, Provenzale JM, et al. Induction of hyperintense signal on T2-weighted MR images correlates with infusion distribution from intracerebral convection-enhanced delivery of a tumor-targeted cytotoxin. AJR Am J Roentgenol. 2007;188(3):703-709.
16. Mardor Y, Roth Y, Lidar Z, et al. Monitoring response to convection-enhanced taxol delivery in brain tumor patients using diffusion-weighted magnetic resonance imaging. Cancer Res. 2001;61(13):4971- 4973.
17. Mardor Y, Rahav O, Zauberman Y, et al. Convection-enhanced drug delivery: Increased efficacy and magnetic resonance image monitoring. Cancer Res. 2005;65(15):6858-6863.
18. Sampson JH, Reardon DA, Friedman AH, et al. Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: Case study. Neuro Oncol. 2005;7(1):90-96.
19. Sampson JH, Akabani G, Friedman AH, et al. Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies. Neurosurg Focus. 2006;20(4):E14.
20. Sampson JH, Akabani G, Archer GE, et al. Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors. Neuro Oncol. 2008; 10(3):320-329.
21. Beers R, Chowdhury P, Bigner D, Pastan I. Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display. Clin Cancer Res. 2000;6(7):2835-2843.
22. Deoni SC, Rutt BK, Peters TM. Rapid combined T1 and T2 mapping using gradient recalled acquisition in the steady state. Magn Reson Med. 2003;49(3): 515-526.
23. Pickup S, Wood AK, Kundel HL. Gadodiamide T1 relaxivity in brain tissue in vivo is lower than in saline. Magn Reson Med. 2005;53(1):35-40.
24. Rohrer M, Bauer H, Mintorovitch J, Requardt M, Weinmann HJ. Comparison of magnetic properties of MRI contrast media solutions at different magnetic field strengths. Invest Radiol. 2005;40(11):715-724.
25. Wells WM III, Viola P, Atsumi H, Nakajima S, Kikinis R. Multi-modal volume registration by maximization ofmutual information. Med Image Anal. 1996;1(1):35-51.
26. Morris JM, Miller GM. Increased signal in the subarachnoid space on fluidattenuated inversion recovery imaging associated with the clearance dynamics of gadolinium chelate: A potential diagnostic pitfall. AJNR Am J Neuroradiol. 2007; 28(10):1964-1967.
27. Bozzao A, Floris R, Fasoli F, Fantozzi LM, Colonnese C, Simonetti G. Cerebrospinal fluid changes after intravenous injection of gadolinium chelate: Assessment by FLAIR MR imaging. Eur Radiol. 2003;13(3):592-597.
28. Ding D, Kanaly CW, Bigner DD, et al. Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1. J Neurooncol. 2010; 98(1):1-7.
29. Ding D, Kanaly CW, Cummings TJ, Ii JE, Raghavan R, Sampson JH. Longterm safety of combined intracerebral delivery of free gadolinium and targeted chemotherapeutic agent PRX321[published online ahead of print]. Neurol Res. 2009.
30. Szerlip NJ, Walbridge S, Yang L, et al. Real-time imaging of convectionenhanced delivery of viruses and virus-sized particles. J Neurosurg. 2007;107(3): 560-567.
31. Thorne RG, Nicholson C. In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proc Natl Acad Sci U S A. 2006;103(14):5567-5572.
32. Morrison PF, Laske DW, Bobo H, Oldfield EH, Dedrick RL. High-flow microinfusion: Tissue penetration and pharmacodynamics. Am J Physiol. 1994;266 (1 pt 2):R292-R305.