Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma

Cancer Research

Volumn 56, Issue 24, 1996, Pages 5631-5637

  Puri, Raj K ^a   Hoon, Dave S ^b   Leland, Pamela ^a   Snoy, Phil ^a   Rand, Robert W ^b   Pastan, Ira ^c   Kreitman, Robert J ^c  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b JOHN WAYNE CANCER INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; PSEUDOMONAS EXOTOXIN; RECOMBINANT INTERLEUKIN 4; RECOMBINANT TOXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOMA; BINDING AFFINITY; BRAIN NECROSIS; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG CEREBROSPINAL FLUID LEVEL; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACEREBRAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR CELL LINE;

ADP RIBOSE TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; ASTROCYTOMA; BACTERIAL TOXINS; BRAIN NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; EXOTOXINS; FEMALE; HUMANS; IMMUNOTOXINS; INJECTIONS, SPINAL; INTERLEUKIN-4; MACACA FASCICULARIS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; VIRULENCE FACTORS;

EID: 0029751129     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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