Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas

International Journal of Cancer

Volumn 129, Issue 1, 2011, Pages 111-121

  Kuan, Chien Tsun ^a   Wakiya, Kenji ^a,c   Keir, Stephen T ^a   Li, Jianjun ^a   Herndon II, James E ^a   Pastan, Ira ^b   Bigner, Darell D ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAITAMA MEDICAL UNIVERSITY INTERNATIONAL MEDICAL CENTER   (Japan)

Author keywords

GPNMB; phage display; recombinant immunotoxin; single chain Fv; yeast display

Indexed keywords

GLYCOPROTEIN; GLYCOPROTEIN NMB ANTIBODY; GLYCOPROTEIN NMB G49 PSEUDOMONAS EXOTOXIN A; IMMUNOTOXIN; PROTEIN ANTIBODY; PSEUDOMONAS EXOTOXIN A SINGLE CHAIN VARIABLE FRAGMENT ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY ISOLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG EFFICACY; GLIOMA; HUMAN; HUMAN CELL; IC 50; MELANOMA; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TARGETING; RAT; TREATMENT RESPONSE;

ANIMALS; CELL LINE, TUMOR; CHROMATOGRAPHY, AFFINITY; FLOW CYTOMETRY; GLIOMA; HUMANS; IMMUNOTOXINS; MELANOMA; MEMBRANE GLYCOPROTEINS; MICE; MICE, NUDE; RECOMBINANT FUSION PROTEINS; SURFACE PLASMON RESONANCE;

EID: 79955406259     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25645     Document Type: Article

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