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Volumn 12, Issue 2, 2012, Pages 133-139

The effect of environmental oxidative stress on airway inflammation

Author keywords

asthma; LPS; oxidative stress; ozone

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CORTICOSTEROID; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; HYALURONIC ACID; REACTIVE OXYGEN METABOLITE; SULFORAPHANE;

EID: 84858157489     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0b013e32835113d6     Document Type: Review
Times cited : (80)

References (86)
  • 4
    • 0028326413 scopus 로고
    • Exacerbations of childhood asthma and ozone pollution in Atlanta
    • DOI 10.1006/enrs.1994.1021
    • White MC, Etzel RA, Wilcox WD, Lloyd C. Exacerbations of childhood asthma and ozone pollution in Atlanta. Environ Res 1994; 65:56-68. (Pubitemid 24123426)
    • (1994) Environmental Research , vol.65 , Issue.1 , pp. 56-68
    • White, M.C.1    Etzel, R.A.2    Wilcox, W.D.3    Lloyd, C.4
  • 5
    • 75849156309 scopus 로고    scopus 로고
    • Age-related association of fine particles and ozone with severe acute asthma in New York City
    • This study demonstrates that ozone and fine particulate matter increase asthma exacerbations in children
    • Silverman RA, Ito K. Age-related association of fine particles and ozone with severe acute asthma in New York City. J Allergy Clin Immunol 2010; 125:367-373; e365. This study demonstrates that ozone and fine particulate matter increase asthma exacerbations in children.
    • (2010) J Allergy Clin Immunol , vol.125
    • Silverman, R.A.1    Ito, K.2
  • 6
    • 84455169594 scopus 로고    scopus 로고
    • Does air pollution increase the effect of aeroallergens on hospitalization for asthma?
    • Cakmak S, Dales RE, Coates F. Does air pollution increase the effect of aeroallergens on hospitalization for asthma? J Allergy Clin Immunol 2012; 129:228-231.
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 228-231
    • Cakmak, S.1    Dales, R.E.2    Coates, F.3
  • 7
    • 0033828309 scopus 로고    scopus 로고
    • Epidemiology of fine particulate air pollution and human health: Biologic mechanisms and who's at risk?
    • Pope CA 3rd. Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who's at risk? Environ Health Perspect 2000; 108 (Suppl 4):713-723.
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 4 , pp. 713-723
    • Pope III, C.A.1
  • 8
    • 84858154528 scopus 로고    scopus 로고
    • High prevalence of childhood asthma in northern Israel is linked to air pollution by particulate matter: Evidence from GIS analysis and bayesian model averaging
    • [Epub ahead of print] This study shows that exposure to particulate matter at a lower concentration than current international air pollution standards is a risk factor for childhood asthma in urban areas
    • Portnov BA, Reiser B, Karkabi K, et al. High prevalence of childhood asthma in northern Israel is linked to air pollution by particulate matter: evidence from GIS analysis and bayesian model averaging. Int J Environ Health Res 2011. [Epub ahead of print] This study shows that exposure to particulate matter at a lower concentration than current international air pollution standards is a risk factor for childhood asthma in urban areas.
    • (2011) Int J Environ Health Res
    • Portnov, B.A.1    Reiser, B.2    Karkabi, K.3
  • 9
    • 13444291580 scopus 로고    scopus 로고
    • Biology of diesel exhaust effects on respiratory function
    • quiz 229
    • Riedl M, Diaz-Sanchez D. Biology of diesel exhaust effects on respiratory function. J Allergy Clin Immunol 2005; 115:221-228; quiz 229.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 221-228
    • Riedl, M.1    Diaz-Sanchez, D.2
  • 10
    • 0036376342 scopus 로고    scopus 로고
    • Endotoxin in the environment: Exposure and effects
    • Rylander R. Endotoxin in the environment: exposure and effects. J Endotoxin Res 2002; 8:241-252.
    • (2002) J Endotoxin Res , vol.8 , pp. 241-252
    • Rylander, R.1
  • 12
    • 72749084374 scopus 로고    scopus 로고
    • Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 years
    • Ryan PH, Bernstein DI, Lockey J, et al. Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 years. Am J Respir Crit Care Med 2009; 180:1068-1075.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 1068-1075
    • Ryan, P.H.1    Bernstein, D.I.2    Lockey, J.3
  • 13
    • 80052019724 scopus 로고    scopus 로고
    • Endotoxin exposure and childhood wheeze and asthma: A meta-analysis of observational studies
    • This meta-analysis concludes that exposure to endotoxin is a risk factor for wheeze in early childhood
    • Mendy A, Gasana J, Vieira ER, et al. Endotoxin exposure and childhood wheeze and asthma: a meta-analysis of observational studies. J Asthma 2011; 48:685-693. This meta-analysis concludes that exposure to endotoxin is a risk factor for wheeze in early childhood.
    • (2011) J Asthma , vol.48 , pp. 685-693
    • Mendy, A.1    Gasana, J.2    Vieira, E.R.3
  • 15
    • 77953547908 scopus 로고    scopus 로고
    • Comparative airway inflammatory response of normal volunteers to ozone and lipopolysaccharide challenge
    • This study demonstrates that ozone and LPS induce neutrophilic inflammation and modify markers of innate immunity
    • Hernandez ML, Harris B, Lay JC, et al. Comparative airway inflammatory response of normal volunteers to ozone and lipopolysaccharide challenge. Inhal Toxicol 2010; 22:648-656. This study demonstrates that ozone and LPS induce neutrophilic inflammation and modify markers of innate immunity.
    • (2010) Inhal Toxicol , vol.22 , pp. 648-656
    • Hernandez, M.L.1    Harris, B.2    Lay, J.C.3
  • 16
    • 77956354815 scopus 로고    scopus 로고
    • Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone
    • This study shows that atopic asthmatic patients have increased airway inflammatory responses in response to ozone
    • Hernandez ML, Lay JC, Harris B, et al. Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone. J Allergy Clin Immunol 2010; 126:537-544; e531. This study shows that atopic asthmatic patients have increased airway inflammatory responses in response to ozone.
    • (2010) J Allergy Clin Immunol , vol.126
    • Hernandez, M.L.1    Lay, J.C.2    Harris, B.3
  • 18
    • 0028201058 scopus 로고
    • Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells
    • Devlin RB, McKinnon KP, Noah T, et al. Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells. Am J Physiol 1994; 266:L612-L619.
    • (1994) Am J Physiol , vol.266
    • Devlin, R.B.1    McKinnon, K.P.2    Noah, T.3
  • 19
    • 15144355007 scopus 로고    scopus 로고
    • Induction of interleukin-8 by ozone is mediated by tyrosine kinase and protein kinase A, but not by protein kinase C
    • DOI 10.1002/(SICI)1097-4652(199811)177:2<313::AID-JCP13>3.0.CO;2-A
    • Jaspers I, Chen LC, Flescher E. Induction of interleukin-8 by ozone is mediated by tyrosine kinase and protein kinase A, but not by protein kinase C. J Cell Physiol 1998; 177:313-323. (Pubitemid 28452832)
    • (1998) Journal of Cellular Physiology , vol.177 , Issue.2 , pp. 313-323
    • Jaspers, I.1    Chen, L.C.2    Flescher, E.3
  • 20
    • 0030898845 scopus 로고    scopus 로고
    • Ozone-induced IL-8 expression and transcription factor binding in respiratory epithelial cells
    • Jaspers I, Flescher E, Chen LC. Ozone-induced IL-8 expression and transcription factor binding in respiratory epithelial cells. Am J Physiol 1997; 272:L504-L511.
    • (1997) Am J Physiol , vol.272
    • Jaspers, I.1    Flescher, E.2    Chen, L.C.3
  • 21
    • 0027225194 scopus 로고
    • In vitro ozone exposure increased release of arachidonic acid products from a human bronchial epithelial cell line
    • DOI 10.1006/taap.1993.1027
    • McKinnon KP, Madden MC, Noah TL, Devlin RB. In vitro ozone exposure increases release of arachidonic acid products from a human bronchial epithelial cell line. Toxicol Appl Pharmacol 1993; 118:215-223. (Pubitemid 23151343)
    • (1993) Toxicology and Applied Pharmacology , vol.118 , Issue.2 , pp. 215-223
    • McKinnon, K.P.1    Madden, M.C.2    Noah, T.L.3    Devlin, R.B.4
  • 22
    • 0035071236 scopus 로고    scopus 로고
    • Effects of ozone exposure on nuclear factor-kappaB activation and tumor necrosis factro-alpha expression in human nasal epithelial cells
    • DOI 10.1093/toxsci/60.2.356
    • Nichols BG, Woods JS, Luchtel DL, et al. Effects of ozone exposure on nuclear factor-kappaB activation and tumor necrosis factor-alpha expression in human nasal epithelial cells. Toxicol Sci 2001; 60:356-362. (Pubitemid 32273325)
    • (2001) Toxicological Sciences , vol.60 , Issue.2 , pp. 356-362
    • Nichols, B.G.1    Woods, J.S.2    Luchtel, D.L.3    Corral, J.4    Koenig, J.Q.5
  • 23
    • 0036847266 scopus 로고    scopus 로고
    • Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles
    • Becker S, Fenton MJ, Soukup JM. Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles. Am J Respir Cell Mol Biol 2002; 27:611-618. (Pubitemid 35307123)
    • (2002) American Journal of Respiratory Cell and Molecular Biology , vol.27 , Issue.5 , pp. 611-618
    • Becker, S.1    Fenton, M.J.2    Soukup, J.M.3
  • 25
    • 2442651697 scopus 로고    scopus 로고
    • Role of hyaluronan and reactive oxygen species in tissue kallikrein-mediated epidermal growth factor receptor activation in human airways
    • DOI 10.1074/jbc.M309950200
    • Casalino-Matsuda SM, Monzon ME, Conner GE, et al. Role of hyaluronan and reactive oxygen species in tissue kallikrein-mediated epidermal growth factor receptor activation in human airways. J Biol Chem 2004; 279:21606-21616. (Pubitemid 38656572)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.20 , pp. 21606-21616
    • Casalino-Matsuda, S.M.1    Monzon, M.E.2    Conner, G.E.3    Salathe, M.4    Forteza, R.M.5
  • 26
    • 77951888462 scopus 로고    scopus 로고
    • TLR4 is necessary for hyaluronanmediated airway hyperresponsiveness after ozone inhalation
    • Garantziotis S, Li Z, Potts EN, et al. TLR4 is necessary for hyaluronanmediated airway hyperresponsiveness after ozone inhalation. Am J Respir Crit Care Med 2010; 181:666-675.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 666-675
    • Garantziotis, S.1    Li, Z.2    Potts, E.N.3
  • 28
    • 33747483267 scopus 로고    scopus 로고
    • The role of Toll-like receptors in non-infectious lung injury
    • DOI 10.1038/sj.cr.7310085, PII 7310085
    • Jiang D, Liang J, Li Y, Noble PW. The role of toll-like receptors in noninfectious lung injury. Cell Res 2006; 16:693-701. (Pubitemid 44258922)
    • (2006) Cell Research , vol.16 , Issue.8 , pp. 693-701
    • Jiang, D.1    Liang, J.2    Li, Y.3    Noble, P.W.4
  • 30
    • 51249093508 scopus 로고    scopus 로고
    • Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells
    • Monzon ME, Manzanares D, Schmid N, et al. Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells. Am J Respir Cell Mol Biol 2008; 39:289-295.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 289-295
    • Monzon, M.E.1    Manzanares, D.2    Schmid, N.3
  • 32
    • 33846516962 scopus 로고    scopus 로고
    • Genetic mechanisms of susceptibility to oxidative lung injury in mice
    • DOI 10.1016/j.freeradbiomed.2006.11.021, PII S0891584906007581
    • Cho HY, Kleeberger SR. Genetic mechanisms of susceptibility to oxidative lung injury in mice. Free Radic Biol Med 2007; 42:433-445. (Pubitemid 46164879)
    • (2007) Free Radical Biology and Medicine , vol.42 , Issue.4 , pp. 433-445
    • Cho, H.-Y.1    Kleeberger, S.R.2
  • 35
    • 77954005130 scopus 로고    scopus 로고
    • Endogenous ligands of TLR2 and TLR4: Agonists or assistants?
    • This review article discusses the role of TLRs in enhancing sensitivity to microbial challenge
    • Erridge C. Endogenous ligands of TLR2 and TLR4: agonists or assistants? J Leukoc Biol 2010; 87:989-999. This review article discusses the role of TLRs in enhancing sensitivity to microbial challenge.
    • (2010) J Leukoc Biol , vol.87 , pp. 989-999
    • Erridge, C.1
  • 36
    • 66449113934 scopus 로고    scopus 로고
    • Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice
    • Garantziotis S, Li Z, Potts EN, et al. Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. J Biol Chem 2009; 284:11309-11317.
    • (2009) J Biol Chem , vol.284 , pp. 11309-11317
    • Garantziotis, S.1    Li, Z.2    Potts, E.N.3
  • 37
    • 0031398530 scopus 로고    scopus 로고
    • Prolonged acute exposure to 0.16 ppm ozone induces eosinophilic airway inflammation in asthmatic subjects with allergies
    • DOI 10.1016/S0091-6749(97)70277-X
    • Peden DB, Boehlecke B, Horstman D, Devlin R. Prolonged acute exposure to 0.16 ppm ozone induces eosinophilic airway inflammation in asthmatic subjects with allergies. J Allergy Clin Immunol 1997; 100:802-808. (Pubitemid 28299000)
    • (1997) Journal of Allergy and Clinical Immunology , vol.100 , Issue.6 I , pp. 802-808
    • Peden, D.B.1    Boehlecke, B.2    Horstman, D.3    Devlin, R.4
  • 39
  • 40
    • 77952497455 scopus 로고    scopus 로고
    • Increase in markers of airway inflammation after ozone exposure can be observed also in stable treated asthmatics with minimal functional response to ozone
    • This study shows that asthmatic patients with a greater functional response to ozone also have greater neutrophil recruitment into airways
    • Vagaggini B, Bartoli ML, Cianchetti S, et al. Increase in markers of airway inflammation after ozone exposure can be observed also in stable treated asthmatics with minimal functional response to ozone. Respir Res 2010; 11:5. This study shows that asthmatic patients with a greater functional response to ozone also have greater neutrophil recruitment into airways.
    • (2010) Respir Res , vol.11 , pp. 5
    • Vagaggini, B.1    Bartoli, M.L.2    Cianchetti, S.3
  • 41
    • 84455206439 scopus 로고    scopus 로고
    • Airway cells from atopic asthmatics exposed to ozone display an enhanced innate immune gene profile
    • Hernandez ML, Alexis BW, Fry NE, et al. Airway cells from atopic asthmatics exposed to ozone display an enhanced innate immune gene profile. J Allergy Clin Immunol 2012; 129:259-261; e2.
    • (2012) J Allergy Clin Immunol , vol.129
    • Hernandez, M.L.1    Alexis, B.W.2    Fry, N.E.3
  • 42
    • 0242552190 scopus 로고    scopus 로고
    • Nicotinamide adenine dinucleotide (phosphate) reduced:quinone oxidoreductase and glutathione S-transferase M1 polymorphisms and childhood asthma
    • David GL, Romieu I, Sienra-Monge JJ, et al. Nicotinamide adenine dinucleotide (phosphate) reduced:quinone oxidoreductase and glutathione S-transferase M1 polymorphisms and childhood asthma. Am J Respir Crit Care Med 2003; 168:1199-1204.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 1199-1204
    • David, G.L.1    Romieu, I.2    Sienra-Monge, J.J.3
  • 44
    • 0037102379 scopus 로고    scopus 로고
    • Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children
    • Gilliland FD, Li YF, Dubeau L, et al. Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med 2002; 166:457-463.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 457-463
    • Gilliland, F.D.1    Li, Y.F.2    Dubeau, L.3
  • 45
    • 79958023999 scopus 로고    scopus 로고
    • The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics
    • Higgins LG, Hayes JD. The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics. Chem Biol Interact 2011; 192:37-45.
    • (2011) Chem Biol Interact , vol.192 , pp. 37-45
    • Higgins, L.G.1    Hayes, J.D.2
  • 46
    • 9744283511 scopus 로고    scopus 로고
    • Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates
    • McWalter GK, Higgins LG, McLellan LI, et al. Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates. J Nutr 2004; 134:3499S-3506S. (Pubitemid 39587596)
    • (2004) Journal of Nutrition , vol.134 , Issue.12 SUPPL.
    • McWalter, G.K.1    Higgins, L.G.2    McLellan, L.I.3    Henderson, C.J.4    Song, L.5    Thornalley, P.J.6    Itoh, K.7    Yamamoto, M.8    Hayes, J.D.9
  • 47
    • 67650729747 scopus 로고    scopus 로고
    • Gene by environment interaction in asthma
    • London SJ, Romieu I. Gene by environment interaction in asthma. Annu Rev Public Health 2009; 30:55-80.
    • (2009) Annu Rev Public Health , vol.30 , pp. 55-80
    • London, S.J.1    Romieu, I.2
  • 48
    • 80052941196 scopus 로고    scopus 로고
    • Enhancement of systemic and sputum granulocyte response to inhaled endotoxin in people with the GSTM1 null genotype
    • This study demonstrates that genotypic differences play a role in response to endotoxin
    • Dillon MA, Harris B, Hernandez ML, et al. Enhancement of systemic and sputum granulocyte response to inhaled endotoxin in people with the GSTM1 null genotype. Occup Environ Med 2011; 68:783-785. This study demonstrates that genotypic differences play a role in response to endotoxin.
    • (2011) Occup Environ Med , vol.68 , pp. 783-785
    • Dillon, M.A.1    Harris, B.2    Hernandez, M.L.3
  • 49
    • 0347948542 scopus 로고    scopus 로고
    • Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: Randomised, placebo-controlled crossover study
    • DOI 10.1016/S0140-6736(03)15262-2
    • Gilliland FD, Li YF, Saxon A, Diaz-Sanchez D. Effect of glutathione-Stransferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study. Lancet 2004; 363:119-125. (Pubitemid 38068328)
    • (2004) Lancet , vol.363 , Issue.9403 , pp. 119-125
    • Gilliland, F.D.1    Li, Y.-F.2    Saxon, A.3    Diaz-Sanchez, D.4
  • 51
    • 71249101959 scopus 로고    scopus 로고
    • The glutathione-S-transferase Mu 1 null genotype modulates ozone-induced airway inflammation in human subjects
    • Alexis NE, Zhou H, Lay JC, et al. The glutathione-S-transferase Mu 1 null genotype modulates ozone-induced airway inflammation in human subjects. J Allergy Clin Immunol 2009; 124:1222-1228; e1225.
    • (2009) J Allergy Clin Immunol , vol.124
    • Alexis, N.E.1    Zhou, H.2    Lay, J.C.3
  • 52
    • 79959343564 scopus 로고    scopus 로고
    • GSTM1 modulation of IL-8 expression in human bronchial epithelial cells exposed to ozone
    • This study shows that GSTM1 deficiency results in increased ozone-induced IL-8 expression, providing in-vitro evidence that this genotypic variation contributes to ozone-induced inflammatory response
    • Wu W, Doreswamy V, Diaz-Sanchez D, et al. GSTM1 modulation of IL-8 expression in human bronchial epithelial cells exposed to ozone. Free Radic Biol Med 2011; 51:522-529. This study shows that GSTM1 deficiency results in increased ozone-induced IL-8 expression, providing in-vitro evidence that this genotypic variation contributes to ozone-induced inflammatory response.
    • (2011) Free Radic Biol Med , vol.51 , pp. 522-529
    • Wu, W.1    Doreswamy, V.2    Diaz-Sanchez, D.3
  • 53
    • 0033651393 scopus 로고    scopus 로고
    • Cyclooxygenase metabolites play a different role in ozone-induced pulmonary function decline in asthmatics compared to normals
    • Alexis N, Urch B, Tarlo S, et al. Cyclooxygenase metabolites play a different role in ozone-induced pulmonary function decline in asthmatics compared to normals. Inhal Toxicol 2000; 12:1205-1224.
    • (2000) Inhal Toxicol , vol.12 , pp. 1205-1224
    • Alexis, N.1    Urch, B.2    Tarlo, S.3
  • 54
    • 0029862866 scopus 로고    scopus 로고
    • Effects of cyclo-oxygenase inhibition on ozone-induced respiratory inflammation and lung function changes
    • Hazucha MJ, Madden M, Pape G, et al. Effects of cyclo-oxygenase inhibition on ozone-induced respiratory inflammation and lung function changes. Eur J Appl Physiol Occup Physiol 1996; 73:17-27.
    • (1996) Eur J Appl Physiol Occup Physiol , vol.73 , pp. 17-27
    • Hazucha, M.J.1    Madden, M.2    Pape, G.3
  • 57
    • 0028808279 scopus 로고
    • Protective effect of sodium cromoglycate on lipopolysaccharide-induced bronchial obstruction in asthmatics
    • Michel O, Ginanni R, Sergysels R. Protective effect of sodium cromoglycate on lipopolysaccharide-induced bronchial obstruction in asthmatics. Int Arch Allergy Immunol 1995; 108:298-302.
    • (1995) Int Arch Allergy Immunol , vol.108 , pp. 298-302
    • Michel, O.1    Ginanni, R.2    Sergysels, R.3
  • 60
    • 79959340752 scopus 로고    scopus 로고
    • SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans
    • This study provides evidence that an antagonist blocking CXCR2 may reduce ozone-induced airway inflammation
    • Lazaar AL, Sweeney LE, MacDonald AJ, et al. SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. Br J Clin Pharmacol 2011; 72:282-293. This study provides evidence that an antagonist blocking CXCR2 may reduce ozone-induced airway inflammation.
    • (2011) Br J Clin Pharmacol , vol.72 , pp. 282-293
    • Lazaar, A.L.1    Sweeney, L.E.2    MacDonald, A.J.3
  • 61
    • 0347319034 scopus 로고    scopus 로고
    • Genetic polymorphism of GSTM1 and antioxidant supplementation influence lung function in relation to ozone exposure in asthmatic children in Mexico City
    • Romieu I, Sienra-Monge JJ, Ramirez-Aguilar M, et al. Genetic polymorphism of GSTM1 and antioxidant supplementation influence lung function in relation to ozone exposure in asthmatic children in Mexico City. Thorax 2004; 59:8-10.
    • (2004) Thorax , vol.59 , pp. 8-10
    • Romieu, I.1    Sienra-Monge, J.J.2    Ramirez-Aguilar, M.3
  • 62
    • 0036724030 scopus 로고    scopus 로고
    • Antioxidant supplementation and lung functions among children with asthma exposed to high levels of air pollutants
    • Romieu I, Sienra-Monge JJ, Ramirez-Aguilar M, et al. Antioxidant supplementation and lung functions among children with asthma exposed to high levels of air pollutants. Am J Respir Crit Care Med 2002; 166:703-709.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 703-709
    • Romieu, I.1    Sienra-Monge, J.J.2    Ramirez-Aguilar, M.3
  • 64
    • 0034741930 scopus 로고    scopus 로고
    • Dietary antioxidants and ozone-induced bronchial hyperresponsiveness in adults with asthma
    • Trenga CA, Koenig JQ, Williams PV. Dietary antioxidants and ozone-induced bronchial hyperresponsiveness in adults with asthma. Arch Environ Health 2001; 56:242-249.
    • (2001) Arch Environ Health , vol.56 , pp. 242-249
    • Trenga, C.A.1    Koenig, J.Q.2    Williams, P.V.3
  • 65
    • 33747771714 scopus 로고    scopus 로고
    • Phase II enzymes induction blocks the enhanced IgE production in B cells by diesel exhaust particles
    • Wan J, Diaz-Sanchez D. Phase II enzymes induction blocks the enhanced IgE production in B cells by diesel exhaust particles. J Immunol 2006; 177:3477-3483. (Pubitemid 44277869)
    • (2006) Journal of Immunology , vol.177 , Issue.5 , pp. 3477-3483
    • Wan, J.1    Diaz-Sanchez, D.2
  • 66
    • 33846300705 scopus 로고    scopus 로고
    • Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract
    • DOI 10.1152/ajplung.00170.2006
    • Ritz SA, Wan J, Diaz-Sanchez D. Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract. Am J Physiol Lung Cell Mol Physiol 2007; 292:L33-L39. (Pubitemid 46110450)
    • (2007) American Journal of Physiology - Lung Cellular and Molecular Physiology , vol.292 , Issue.1
    • Ritz, S.A.1    Wan, J.2    Diaz-Sanchez, D.3
  • 67
    • 59249103720 scopus 로고    scopus 로고
    • Oral sulforaphane increases phase II antioxidant enzymes in the human upper airway
    • Riedl MA, Saxon A, Diaz-Sanchez D. Oral sulforaphane increases phase II antioxidant enzymes in the human upper airway. Clin Immunol 2009; 130:244-251.
    • (2009) Clin Immunol , vol.130 , pp. 244-251
    • Riedl, M.A.1    Saxon, A.2    Diaz-Sanchez, D.3
  • 68
    • 58149181699 scopus 로고    scopus 로고
    • Airway glutathione homeostasis is altered in children with severe asthma: Evidence for oxidant stress
    • Fitzpatrick AM, Teague WG, Holguin F, et al. Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress. J Allergy Clin Immunol 2009; 123:146-152; e148.
    • (2009) J Allergy Clin Immunol , vol.123
    • Fitzpatrick, A.M.1    Teague, W.G.2    Holguin, F.3
  • 69
    • 79957849132 scopus 로고    scopus 로고
    • Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2
    • This study shows that antioxidant defense is impaired in children with severe asthma
    • Fitzpatrick AM, Stephenson ST, Hadley GR, et al. Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2. J Allergy Clin Immunol 2011; 127:1604-1611. This study shows that antioxidant defense is impaired in children with severe asthma.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1604-1611
    • Fitzpatrick, A.M.1    Stephenson, S.T.2    Hadley, G.R.3
  • 70
    • 78649849976 scopus 로고    scopus 로고
    • Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma
    • This study demonstrates a relationship between maternal antioxidant gene polymorphisms and acetaminophen use in late pregnancy and development of asthma in the child
    • Shaheen SO, Newson RB, Ring SM, et al. Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma. J Allergy Clin Immunol 2010; 126:1141-1148; e1147. This study demonstrates a relationship between maternal antioxidant gene polymorphisms and acetaminophen use in late pregnancy and development of asthma in the child.
    • (2010) J Allergy Clin Immunol , vol.126
    • Shaheen, S.O.1    Newson, R.B.2    Ring, S.M.3
  • 71
    • 80052265103 scopus 로고    scopus 로고
    • Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress
    • This study suggests that downregulation of GSTPi after allergen exposure contributes to increased oxidative stress and the asthma phenotype. This may provide a therapeutic target for affected individuals
    • Schroer KT, Gibson AM, Sivaprasad U, et al. Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress. J Allergy Clin Immunol 2011; 128:539-548. This study suggests that downregulation of GSTPi after allergen exposure contributes to increased oxidative stress and the asthma phenotype. This may provide a therapeutic target for affected individuals.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 539-548
    • Schroer, K.T.1    Gibson, A.M.2    Sivaprasad, U.3
  • 72
    • 80051563677 scopus 로고    scopus 로고
    • Update in Environmental and Occupational Medicine 2010
    • Budinger GRS, Mutlu GM. Update in Environmental and Occupational Medicine 2010. Am J Respir Crit Care Med 2011; 183:1614-1619.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1614-1619
    • Budinger, G.R.S.1    Mutlu, G.M.2
  • 73
    • 80052941196 scopus 로고    scopus 로고
    • Enhancement of systemic and sputum granulocyte response to inhaled endotoxin in people with the GSTM1 null genotype
    • 48
    • Dillon MA, Harris B, Hernandez ML, et al. Enhancement of systemic and sputum granulocyte response to inhaled endotoxin in people with the GSTM1 null genotype. Occup Environ Med 2011; 68:783-785. [48]
    • (2011) Occup Environ Med , vol.68 , pp. 783-785
    • Dillon, M.A.1    Harris, B.2    Hernandez, M.L.3
  • 74
    • 77954005130 scopus 로고    scopus 로고
    • Endogenous ligands of TLR2 and TLR4: Agonists or assistants?
    • 35
    • Erridge C. Endogenous ligands of TLR2 and TLR4: agonists or assistants? J Leukoc Biol 2010; 87:989-999. [35]
    • (2010) J Leukoc Biol , vol.87 , pp. 989-999
    • Erridge, C.1
  • 75
    • 79957849132 scopus 로고    scopus 로고
    • Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2
    • 69
    • Fitzpatrick AM, Stephenson ST, Hadley GR, et al. Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2. J Allergy Clin Immunol 2011; 127:1604-1611. [69]
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1604-1611
    • Fitzpatrick, A.M.1    Stephenson, S.T.2    Hadley, G.R.3
  • 76
    • 80052263689 scopus 로고    scopus 로고
    • Proliferation of CD8-Positive T Cells in Blood Vessels of Rat Renal Allografts
    • Grau V, Fuchs-Moll G, Wilker S, Weimer R, et al. Proliferation of CD8-Positive T Cells in Blood Vessels of Rat Renal Allografts. Am J Transplant 2011; 11:1979-1985.
    • (2011) Am J Transplant , vol.11 , pp. 1979-1985
    • Grau, V.1    Fuchs-Moll, G.2    Wilker, S.3    Weimer, R.4
  • 77
    • 77953547908 scopus 로고    scopus 로고
    • Comparative airway inflammatory response of normal volunteers to ozone and lipopolysaccharide challenge
    • 15
    • Hernandez ML, Harris B, Lay JC, et al. Comparative airway inflammatory response of normal volunteers to ozone and lipopolysaccharide challenge. Inhal Toxicol 2010; 22:648-656. [15]
    • (2010) Inhal Toxicol , vol.22 , pp. 648-656
    • Hernandez, M.L.1    Harris, B.2    Lay, J.C.3
  • 78
    • 77956354815 scopus 로고    scopus 로고
    • Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone
    • 16
    • Hernandez ML, Lay JC, Harris B, et al. Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone. J Allergy Clin Immunol 2010; 126:537-544. e531 [16]
    • (2010) J Allergy Clin Immunol , vol.126
    • Hernandez, M.L.1    Lay, J.C.2    Harris, B.3
  • 79
    • 79959340752 scopus 로고    scopus 로고
    • SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans
    • 60
    • Lazaar AL, Sweeney LE, MacDonald AJ, et al. SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. Br J Clin Pharmacol 2011; 72:282-293. [60]
    • (2011) Br J Clin Pharmacol , vol.72 , pp. 282-293
    • Lazaar, A.L.1    Sweeney, L.E.2    MacDonald, A.J.3
  • 80
    • 80052019724 scopus 로고    scopus 로고
    • Endotoxin exposure and childhood wheeze and asthma: A meta-analysis of observational studies
    • 13
    • Mendy A, Gasana J, Vieira ER, et al. Endotoxin exposure and childhood wheeze and asthma: a meta-analysis of observational studies. J Asthma 2011; 48:685-693. [13]
    • (2011) J Asthma , vol.48 , pp. 685-693
    • Mendy, A.1    Gasana, J.2    Vieira, E.R.3
  • 81
    • 84858154528 scopus 로고    scopus 로고
    • High prevalence of childhood asthma in northern Israel is linked to air pollution by particulate matter: Evidence from GIS analysis and bayesian model averaging
    • Epub ahead of print [08]
    • Portnov BA, Reiser B, Karkabi K, et al. High prevalence of childhood asthma in northern Israel is linked to air pollution by particulate matter: evidence from GIS analysis and bayesian model averaging. Int J Environ Health Res 2011. [Epub ahead of print] [08]
    • (2011) Int J Environ Health Res
    • Portnov, B.A.1    Reiser, B.2    Karkabi, K.3
  • 82
    • 80052265103 scopus 로고    scopus 로고
    • Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress
    • 71
    • Schroer KT, Gibson AM, Sivaprasad U, et al. Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress. J Allergy Clin Immunol 2011; 128:539-548. [71]
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 539-548
    • Schroer, K.T.1    Gibson, A.M.2    Sivaprasad, U.3
  • 83
    • 78649849976 scopus 로고    scopus 로고
    • Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma
    • 70
    • Shaheen SO, Newson RB, Ring SM, et al. Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma. J Allergy Clin Immunol 2010; 126:1141-1148. e1147 [70]
    • (2010) J Allergy Clin Immunol , vol.126
    • Shaheen, S.O.1    Newson, R.B.2    Ring, S.M.3
  • 84
    • 75849156309 scopus 로고    scopus 로고
    • Age-related association of fine particles and ozone with severe acute asthma in New York City
    • 05
    • Silverman RA, Ito K. Age-related association of fine particles and ozone with severe acute asthma in New York City. J Allergy Clin Immunol 2010; 125:367-373. e365 [05]
    • (2010) J Allergy Clin Immunol , vol.125
    • Silverman, R.A.1    Ito, K.2
  • 85
    • 77952497455 scopus 로고    scopus 로고
    • Increase in markers of airway inflammation after ozone exposure can be observed also in stable treated asthmatics with minimal functional response to ozone
    • 40
    • Vagaggini B, Bartoli ML, Cianchetti S, et al. Increase in markers of airway inflammation after ozone exposure can be observed also in stable treated asthmatics with minimal functional response to ozone. Respir Res 2010; 11:5. [40]
    • (2010) Respir Res , vol.11 , pp. 5
    • Vagaggini, B.1    Bartoli, M.L.2    Cianchetti, S.3
  • 86
    • 79959343564 scopus 로고    scopus 로고
    • GSTM1 modulation of IL-8 expression in human bronchial epithelial cells exposed to ozone
    • 52
    • Wu W, Doreswamy V, Diaz-Sanchez D, et al. GSTM1 modulation of IL-8 expression in human bronchial epithelial cells exposed to ozone. Free Radic Biol Med 2011; 51:522-529. [52]
    • (2011) Free Radic Biol Med , vol.51 , pp. 522-529
    • Wu, W.1    Doreswamy, V.2    Diaz-Sanchez, D.3


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