-
1
-
-
77955273537
-
-
Lyon, GLOBOCAN, France: International Agency for Research on Cancer. Retrieved March 1, 2011. Available from: URL
-
Ferlay J, Shin H, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 10. Lyon, France: International Agency for Research on Cancer. Retrieved March 1, 2011. Available from: URL: http://globocan.iarc.fr.
-
(2008)
Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 10
-
-
Ferlay, J.1
Shin, H.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon EF, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990; 61: 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.F.1
Vogelstein, B.2
-
3
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
Fearon ER. Molecular genetics of colorectal cancer. Annu Rev Pathol. 2011; 6: 479-507.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
4
-
-
47049116663
-
Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells
-
Oguma K, Oshima H, Aoki M, Uchio R, Naka K, Nakamura S, et al. Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells. EMBO J. 2008; 27: 1671-1681.
-
(2008)
EMBO J
, vol.27
, pp. 1671-1681
-
-
Oguma, K.1
Oshima, H.2
Aoki, M.3
Uchio, R.4
Naka, K.5
Nakamura, S.6
-
5
-
-
73449139396
-
The NF-κB/AKTdependent induction of Wnt signaling in colon cancer cells by macrophages and IL-1β
-
Kaler P, Godasi BN, Augenlicht L, Klampfer L. The NF-κB/AKTdependent induction of Wnt signaling in colon cancer cells by macrophages and IL-1β. Cancer Microenviron. 2009; 2: 69-80.
-
(2009)
Cancer Microenviron
, vol.2
, pp. 69-80
-
-
Kaler, P.1
Godasi, B.N.2
Augenlicht, L.3
Klampfer, L.4
-
6
-
-
28544444039
-
Prostaglandin E2 promotes colon cancer cell growth through a Gsaxin-β-catenin signaling axis
-
Castellone MD, Teramoto H, Williams BO, Druey KM, Gutkind JS. Prostaglandin E2 promotes colon cancer cell growth through a Gsaxin-β-catenin signaling axis. Science. 2005; 310: 1504-1510.
-
(2005)
Science
, vol.310
, pp. 1504-1510
-
-
Castellone, M.D.1
Teramoto, H.2
Williams, B.O.3
Druey, K.M.4
Gutkind, J.S.5
-
7
-
-
77958187285
-
Intestinal stem cells
-
Umar S. Intestinal stem cells. Curr Gastroenterol Rep. 2010; 12: 340-348.
-
(2010)
Curr Gastroenterol Rep
, vol.12
, pp. 340-348
-
-
Umar, S.1
-
8
-
-
77955383804
-
An innately dangerous balancing act: Intestinal homeostasis, inflammation, and colitis-associated cancer
-
Asquith M, Powrie F. An innately dangerous balancing act: Intestinal homeostasis, inflammation, and colitis-associated cancer. J Exp Med. 2010; 207: 1573-1577.
-
(2010)
J Exp Med
, vol.207
, pp. 1573-1577
-
-
Asquith, M.1
Powrie, F.2
-
9
-
-
57549101916
-
Bacterial-mucosal interactions in inflammatory bowel disease: An alliance gone bad
-
Chichlowski M, Hale LP. Bacterial-mucosal interactions in inflammatory bowel disease: an alliance gone bad. Am J Physiol Gastrointest Liver Physiol. 2008; 295: G1139-G1149.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.295
-
-
Chichlowski, M.1
Hale, L.P.2
-
10
-
-
0035865012
-
Cancer risk in patients with inflammatory bowel disease: A population-based study
-
Bernstein CN, Blanchard JF, Kliewer E, Wajda A. Cancer risk in patients with inflammatory bowel disease: a population-based study. Cancer. 2001; 91: 854-862.
-
(2001)
Cancer
, vol.91
, pp. 854-862
-
-
Bernstein, C.N.1
Blanchard, J.F.2
Kliewer, E.3
Wajda, A.4
-
11
-
-
0033980980
-
Colorectal cancer prevention in ulcerative colitis: A case-control study
-
Eaden J, Abrams K, Ekbom A, Jackson E, Mayberry J. Colorectal cancer prevention in ulcerative colitis: a case-control study. Aliment Pharmacol Ther. 2000; 14: 145-153.
-
(2000)
Aliment Pharmacol Ther
, vol.14
, pp. 145-153
-
-
Eaden, J.1
Abrams, K.2
Ekbom, A.3
Jackson, E.4
Mayberry, J.5
-
12
-
-
33646875285
-
Meta-analysis: Colorectal and small bowel cancer risk in patients with Crohn's disease
-
Canavan C, Abrams KR, Mayberry J. Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn's disease. Aliment Pharmacol Ther. 2006; 23: 1097-1104.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 1097-1104
-
-
Canavan, C.1
Abrams, K.R.2
Mayberry, J.3
-
13
-
-
0023856775
-
Colorectal cancer in ulcerative colitis: A cohort study of primary referrals from three centres
-
Gyde SN, Prior P, Allan RN, Stevens A, Jewell DP, Truelove SC, et al. Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres. Gut. 1988; 29: 206-217.
-
(1988)
Gut
, vol.29
, pp. 206-217
-
-
Gyde, S.N.1
Prior, P.2
Allan, R.N.3
Stevens, A.4
Jewell, D.P.5
Truelove, S.C.6
-
14
-
-
34848893583
-
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: A cohort study
-
Gupta RB, Harpaz N, Itzkowitz S, Hossain S, Matula S, Kornbluth A, et al. Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology. 2007; 133: 1099-1105.
-
(2007)
Gastroenterology
, vol.133
, pp. 1099-1105
-
-
Gupta, R.B.1
Harpaz, N.2
Itzkowitz, S.3
Hossain, S.4
Matula, S.5
Kornbluth, A.6
-
15
-
-
46749111024
-
Apc mice: Models, modifiers, and mutants
-
McCart AE, Vickaryous NK, Silver A. Apc mice: Models, modifiers, and mutants. Pathol Res Pract. 2008; 204: 479-490.
-
(2008)
Pathol Res Pract
, vol.204
, pp. 479-490
-
-
McCart, A.E.1
Vickaryous, N.K.2
Silver, A.3
-
16
-
-
27944442806
-
Min/+mice: Inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms
-
Min/+mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms. Int J Cancer. 2006; 118: 25-34.
-
(2006)
Int J Cancer
, vol.118
, pp. 25-34
-
-
Tanaka, T.1
Kohno, H.2
Suzuki, R.3
Hata, K.4
Sugie, S.5
Niho, N.6
-
19
-
-
18744388600
-
Morphology of colorectal lymphoid aggregates in cancer, diverticular and inflammatory bowel diseases
-
Nascimbeni R, Di Fabio F, Di Betta E, Mariani P, Fisogni S, Villanacci V. Morphology of colorectal lymphoid aggregates in cancer, diverticular and inflammatory bowel diseases. Mod Pathol. 2005; 18: 681-685.
-
(2005)
Mod Pathol
, vol.18
, pp. 681-685
-
-
Nascimbeni, R.1
di Fabio, F.2
di Betta, E.3
Mariani, P.4
Fisogni, S.5
Villanacci, V.6
-
21
-
-
77950420796
-
Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis
-
Chae WJ, Gibsona TF, Zelterman D, Hao L, Henegariu O, Bothwella ALM. Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis. Proc Natl Acad Sci USA. 2010; 107: 5540-5544.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5540-5544
-
-
Chae, W.J.1
Gibsona, T.F.2
Zelterman, D.3
Hao, L.4
Henegariu, O.5
Bothwella, A.L.M.6
-
22
-
-
35648946229
-
Chronic inflammation and oxidative stress in human carcinogenesis
-
Federico A, Morgillo F, Tuccillo C, Ciardiello F, Loguercio C. Chronic inflammation and oxidative stress in human carcinogenesis. Int J Cancer. 2007; 121: 2381-2386.
-
(2007)
Int J Cancer
, vol.121
, pp. 2381-2386
-
-
Federico, A.1
Morgillo, F.2
Tuccillo, C.3
Ciardiello, F.4
Loguercio, C.5
-
23
-
-
79952474331
-
Reactive species and DNA damage in chronic inflammation: Reconciling chemical mechanisms and biological fates
-
Lonkar P, Dedon PC. Reactive species and DNA damage in chronic inflammation: Reconciling chemical mechanisms and biological fates. Int J Cancer. 2011; 128: 1999-2009.
-
(2011)
Int J Cancer
, vol.128
, pp. 1999-2009
-
-
Lonkar, P.1
Dedon, P.C.2
-
24
-
-
0031984809
-
Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression
-
Ambs S, Merriam WG, Bennett WP, Felley-Bosco E, Ogunfusika MO, Oser SM, et al. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res. 1998; 58: 334-341.
-
(1998)
Cancer Res
, vol.58
, pp. 334-341
-
-
Ambs, S.1
Merriam, W.G.2
Bennett, W.P.3
Felley-Bosco, E.4
Ogunfusika, M.O.5
Oser, S.M.6
-
25
-
-
0035577764
-
Min/+ mice by inhibiting nitric oxide production
-
Min/+ mice by inhibiting nitric oxide production. Cancer Res. 2001; 61: 8357-8360.
-
(2001)
Cancer Res
, vol.61
, pp. 8357-8360
-
-
Ahn, B.1
Ohshima, H.2
-
27
-
-
0034492927
-
The role of cyclooxygenase 2 in ulcerative colitis-associated neoplasia
-
Agoff SN, Brentnall TA, Crispin DA, Taylor SL, Raaka S, Haggitt RC, et al. The role of cyclooxygenase 2 in ulcerative colitis-associated neoplasia. Am J Pathol. 2000; 157: 737-745.
-
(2000)
Am J Pathol
, vol.157
, pp. 737-745
-
-
Agoff, S.N.1
Brentnall, T.A.2
Crispin, D.A.3
Taylor, S.L.4
Raaka, S.5
Haggitt, R.C.6
-
28
-
-
0032920064
-
Early expression of cyclo-oxygenase-2 during sporadic colorectal carcinogenesis
-
Hao X, Bishop AE, Wallace M, Wang H, Willcocks TC, Maclouf J, et al. Early expression of cyclo-oxygenase-2 during sporadic colorectal carcinogenesis. J Pathol. 1999; 187: 295-301.
-
(1999)
J Pathol
, vol.187
, pp. 295-301
-
-
Hao, X.1
Bishop, A.E.2
Wallace, M.3
Wang, H.4
Willcocks, T.C.5
Maclouf, J.6
-
29
-
-
0029117472
-
Expression of cyclooxygenase-1 and -2 in human colorectal cancer
-
Sano H, Kawahito Y, Wilder RL, Hashiramoto A, Mukai S, Asai K, et al. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res. 1995; 55: 3785-3789.
-
(1995)
Cancer Res
, vol.55
, pp. 3785-3789
-
-
Sano, H.1
Kawahito, Y.2
Wilder, R.L.3
Hashiramoto, A.4
Mukai, S.5
Asai, K.6
-
30
-
-
0034282465
-
Genetic disruption of Ptgs-1, as well as of Ptgs-2, reduces intestinal tumorigenesis in Min Mice
-
Chulada PC, Thompson MB, Mahler JF, Doyle CM, Gaul BW, Lee C, et al. Genetic disruption of Ptgs-1, as well as of Ptgs-2, reduces intestinal tumorigenesis in Min Mice. Cancer Res. 2000; 60: 4705-4708.
-
(2000)
Cancer Res
, vol.60
, pp. 4705-4708
-
-
Chulada, P.C.1
Thompson, M.B.2
Mahler, J.F.3
Doyle, C.M.4
Gaul, B.W.5
Lee, C.6
-
31
-
-
0028261042
-
Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2
-
Pugh S, Thomas GAO. Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2. Gut. 1994; 35: 675-678.
-
(1994)
Gut
, vol.35
, pp. 675-678
-
-
Pugh, S.1
Thomas, G.A.O.2
-
32
-
-
44849085464
-
Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis
-
Nakanishi M, Montrose DC, Clark P, Nambiar PR, Belinsky GS, Claffey KP, et al. Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis. Cancer Res. 2008; 68: 3251-3259.
-
(2008)
Cancer Res
, vol.68
, pp. 3251-3259
-
-
Nakanishi, M.1
Montrose, D.C.2
Clark, P.3
Nambiar, P.R.4
Belinsky, G.S.5
Claffey, K.P.6
-
33
-
-
0030468818
-
Cyclooxygenase, NSAIDs, and colorectal cancer
-
DuBois RN, Smalley WE. Cyclooxygenase, NSAIDs, and colorectal cancer. J Gastroenterol. 1996; 31: 898-906.
-
(1996)
J Gastroenterol
, vol.31
, pp. 898-906
-
-
Dubois, R.N.1
Smalley, W.E.2
-
35
-
-
0032897353
-
Min mouse by piroxicam: Kinetics, strain effects, and resistance to chemosuppression
-
Min mouse by piroxicam: kinetics, strain effects, and resistance to chemosuppression. Carcinogenesis. 1999; 20: 51-58.
-
(1999)
Carcinogenesis
, vol.20
, pp. 51-58
-
-
Ritland, S.R.1
Gendler, S.J.2
-
37
-
-
34248157118
-
Effect of aspirin on long-term risk of colorectal cancer: Consistent evidence from randomised and observational studies
-
Flossmann E, Rothwell PM. Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies. Lancet. 2007; 369: 1603-1613.
-
(2007)
Lancet
, vol.369
, pp. 1603-1613
-
-
Flossmann, E.1
Rothwell, P.M.2
-
38
-
-
78650215449
-
Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials
-
Rothwell PM, Wilson M, Elwin CE, Norrving B, Algra A, Warlow CP, et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet. 2010; 376: 1741-1750.
-
(2010)
Lancet
, vol.376
, pp. 1741-1750
-
-
Rothwell, P.M.1
Wilson, M.2
Elwin, C.E.3
Norrving, B.4
Algra, A.5
Warlow, C.P.6
-
39
-
-
33947545402
-
The use of aspirin for primary prevention of colorectal cancer: A systematic review prepared for the U.S. preventive services task force
-
Dubé C, Rostom A, Lewin G, Tsertsvadze A, Barrowman N, Code C, et al. The use of aspirin for primary prevention of colorectal cancer: A systematic review prepared for the U.S. preventive services task force. Ann Intern Med. 2007; 146: 365-375.
-
(2007)
Ann Intern Med
, vol.146
, pp. 365-375
-
-
Dubé, C.1
Rostom, A.2
Lewin, G.3
Tsertsvadze, A.4
Barrowman, N.5
Code, C.6
-
40
-
-
60749136576
-
Nonsteroidal anti-inflammatory drug use after 3 years of aspirin use and colorectal adenoma risk: Observational follow-up of a randomized study
-
Grau MV, Sandler RS, McKeown-Eyssen G, Bresalier RS, Haile RW, Barry EL, et al. Nonsteroidal anti-inflammatory drug use after 3 years of aspirin use and colorectal adenoma risk: Observational follow-up of a randomized study. J Natl Cancer Inst. 2009; 101: 267-276.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 267-276
-
-
Grau, M.V.1
Sandler, R.S.2
McKeown-Eyssen, G.3
Bresalier, R.S.4
Haile, R.W.5
Barry, E.L.6
-
41
-
-
77649210149
-
Chemoprevention of colorectal cancer: Systematic review and economic evaluation
-
Cooper K, Squires H, Carroll C, Papaioannou D, Booth A, Logan RF, et al. Chemoprevention of colorectal cancer: Systematic review and economic evaluation. Health Technol Assess. 2010; 14: 201-206.
-
(2010)
Health Technol Assess
, vol.14
, pp. 201-206
-
-
Cooper, K.1
Squires, H.2
Carroll, C.3
Papaioannou, D.4
Booth, A.5
Logan, R.F.6
-
42
-
-
21444450527
-
Low-dose aspirin in the primary prevention of cancer
-
Cook NR, Lee IM, Gaziano JM, Gordon D, Ridker PM, Manson JE, et al. Low-dose aspirin in the primary prevention of cancer. JAMA. 2005; 294: 47-55.
-
(2005)
JAMA
, vol.294
, pp. 47-55
-
-
Cook, N.R.1
Lee, I.M.2
Gaziano, J.M.3
Gordon, D.4
Ridker, P.M.5
Manson, J.E.6
-
43
-
-
77649239393
-
Serum interleukin-6 levels in colorectal cancer patients--a summary of published results
-
Knüpfer H, Preiss R. Serum interleukin-6 levels in colorectal cancer patients--a summary of published results. Int J Colorectal Dis. 2010; 25: 135-140.
-
(2010)
Int J Colorectal Dis
, vol.25
, pp. 135-140
-
-
Knüpfer, H.1
Preiss, R.2
-
44
-
-
49649127459
-
Influence of interleukin-8 and interleukin-10 on sporadic colon cancer development and progression
-
Cacev T, Radosević S, Krizanac S, Kapitanović S. Influence of interleukin-8 and interleukin-10 on sporadic colon cancer development and progression. Carcinogenesis. 2008; 29: 1572-1580.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1572-1580
-
-
Cacev, T.1
Radosević, S.2
Krizanac, S.3
Kapitanović, S.4
-
45
-
-
3142732009
-
The pattern of cytokine gene expression in human colorectal carcinoma
-
Csiszár A, Szentes T, Haraszti B, Balázs A, Petrányi GG, Pócsik É. The pattern of cytokine gene expression in human colorectal carcinoma. Pathol Oncol Res. 2004; 10: 109-116.
-
(2004)
Pathol Oncol Res
, vol.10
, pp. 109-116
-
-
Csiszár, A.1
Szentes, T.2
Haraszti, B.3
Balázs, A.4
Petrányi, G.G.5
Pócsik, É.6
-
46
-
-
34247596583
-
Reduced expression of microenvironmental Th1 cytokines accompanies adenomas-carcinomas sequence of colorectum
-
Cui G, Goll R, Olsen T, Eriksson Steigen S, Husebekk A, Vonen B, et al. Reduced expression of microenvironmental Th1 cytokines accompanies adenomas-carcinomas sequence of colorectum. Cancer Immunol Immunother. 2007; 56: 985-995.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 985-995
-
-
Cui, G.1
Goll, R.2
Olsen, T.3
Eriksson Steigen, S.4
Husebekk, A.5
Vonen, B.6
-
47
-
-
67149093244
-
Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis
-
Onizawa M, Nagaishi T, Kanai T, Nagano K-I, Oshima S, Nemoto Y, et al. Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis. Am J Physiol Gastrointest Liver Physiol. 2009; 296: G850-G859.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
-
-
Onizawa, M.1
Nagaishi, T.2
Kanai, T.3
Nagano, K.-I.4
Oshima, S.5
Nemoto, Y.6
-
48
-
-
38849171267
-
Blocking TNF- α in mice reduces colorectal carcinogenesis associated with chronic colitis
-
Popivanova BK, Kitamura K, Wu Y, Kondo T, Kagaya T, Kaneko S, et al. Blocking TNF- α in mice reduces colorectal carcinogenesis associated with chronic colitis. J Clin Invest. 2008; 118: 560-570.
-
(2008)
J Clin Invest
, vol.118
, pp. 560-570
-
-
Popivanova, B.K.1
Kitamura, K.2
Wu, Y.3
Kondo, T.4
Kagaya, T.5
Kaneko, S.6
-
49
-
-
77949912764
-
Genetic ablation of Tnfα demonstrates no detectable suppressive effect on inflammation-related mouse colon tumorigenesis
-
Sakai H, Yamada Y, Shimizu M, Saito K, Moriwaki H, Hara A. Genetic ablation of Tnfα demonstrates no detectable suppressive effect on inflammation-related mouse colon tumorigenesis. Chem Biol Interact. 2010; 184: 423-430.
-
(2010)
Chem Biol Interact
, vol.184
, pp. 423-430
-
-
Sakai, H.1
Yamada, Y.2
Shimizu, M.3
Saito, K.4
Moriwaki, H.5
Hara, A.6
-
50
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell. 2009; 15: 103-113.
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.Y.5
Vallabhapurapu, S.6
-
51
-
-
38949137388
-
Interleukin-6 and cachexia in ApcMin/+ mice
-
Baltgalvis KA, Berger FG, Pena MMO, Davis JM, Muga SJ, Carson JA. Interleukin-6 and cachexia in ApcMin/+ mice. Am J Physiol Regul Integr Comp Physiol. 2008; 294: R393-R401.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
-
-
Baltgalvis, K.A.1
Berger, F.G.2
Pena, M.M.O.3
Davis, J.M.4
Muga, S.J.5
Carson, J.A.6
-
53
-
-
33745118276
-
Induction of inflammatory bowel disease accelerates adenoma formation in Min+/- mice
-
Huang EH, Park JC, Appelman H, Weinberg AD, Banerjee M, Logsdon CD, et al. Induction of inflammatory bowel disease accelerates adenoma formation in Min+/- mice. Surgery. 2006; 139: 782-788.
-
(2006)
Surgery
, vol.139
, pp. 782-788
-
-
Huang, E.H.1
Park, J.C.2
Appelman, H.3
Weinberg, A.D.4
Banerjee, M.5
Logsdon, C.D.6
-
55
-
-
33750565444
-
Transforming growth factor β receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation
-
Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, et al. Transforming growth factor β receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Res. 2006; 66: 9837-9844.
-
(2006)
Cancer Res
, vol.66
, pp. 9837-9844
-
-
Muñoz, N.M.1
Upton, M.2
Rojas, A.3
Washington, M.K.4
Lin, L.5
Chytil, A.6
-
56
-
-
33744978564
-
NF-κB and cancer: Mechanisms and targets
-
Karin M. NF-κB and cancer: mechanisms and targets. Mol Carcinog. 2006; 45: 355-361.
-
(2006)
Mol Carcinog
, vol.45
, pp. 355-361
-
-
Karin, M.1
-
57
-
-
0034124076
-
Therapeutic effect of intracolonically administered nuclear factor κB (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis
-
Murano M, Maemura K, Hirata I, Toshina K, Nishikawa T, Hamamoto N, et al. Therapeutic effect of intracolonically administered nuclear factor κB (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis. Clin Exp Immunol. 2000; 120: 51-58.
-
(2000)
Clin Exp Immunol
, vol.120
, pp. 51-58
-
-
Murano, M.1
Maemura, K.2
Hirata, I.3
Toshina, K.4
Nishikawa, T.5
Hamamoto, N.6
-
58
-
-
0346095203
-
An inhibitor of IκB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice
-
MacMaster JF, Dambach DM, Lee DB, Berry KK, Qiu Y, Zusi F, et al. An inhibitor of IκB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice. Inflamm Res. 2003; 52: 508-511.
-
(2003)
Inflamm Res
, vol.52
, pp. 508-511
-
-
Macmaster, J.F.1
Dambach, D.M.2
Lee, D.B.3
Berry, K.K.4
Qiu, Y.5
Zusi, F.6
-
59
-
-
38449110152
-
Cutting edge: The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
-
Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, et al. Cutting edge: The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis. J Immunol. 2007; 179: 2681-2685.
-
(2007)
J Immunol
, vol.179
, pp. 2681-2685
-
-
Shibata, W.1
Maeda, S.2
Hikiba, Y.3
Yanai, A.4
Ohmae, T.5
Sakamoto, K.6
-
60
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, et al. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature. 2007; 446: 557-561.
-
(2007)
Nature
, vol.446
, pp. 557-561
-
-
Nenci, A.1
Becker, C.2
Wullaert, A.3
Gareus, R.4
van Loo, G.5
Danese, S.6
-
61
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, et al. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 2004; 118: 285-296.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.W.5
Egan, L.J.6
-
62
-
-
70349652354
-
Effectiveness of IκB kinase inhibitors in murine colitis-associated tumorigenesis
-
Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, et al. Effectiveness of IκB kinase inhibitors in murine colitis-associated tumorigenesis. J Gastroenterol. 2009; 44: 935-943.
-
(2009)
J Gastroenterol
, vol.44
, pp. 935-943
-
-
Hayakawa, Y.1
Maeda, S.2
Nakagawa, H.3
Hikiba, Y.4
Shibata, W.5
Sakamoto, K.6
-
63
-
-
37549004392
-
Nuclear factor-κB activation: From bench to bedside
-
Sethi G, Sung B, Aggarwal BB. Nuclear factor-κB activation: From bench to bedside. Exp Biol Med. 2008; 233: 21-31.
-
(2008)
Exp Biol Med
, vol.233
, pp. 21-31
-
-
Sethi, G.1
Sung, B.2
Aggarwal, B.B.3
-
64
-
-
28844483212
-
Nuclear factor κB is downregulated and correlates with p53 in the Min mouse mucosa during an accelerated tumor growth
-
Rajakangas J, Pajari AM, Misikangas M, Mutanen M. Nuclear factor κB is downregulated and correlates with p53 in the Min mouse mucosa during an accelerated tumor growth. Int J Cancer. 2006; 118: 279-283.
-
(2006)
Int J Cancer
, vol.118
, pp. 279-283
-
-
Rajakangas, J.1
Pajari, A.M.2
Misikangas, M.3
Mutanen, M.4
-
65
-
-
0034896686
-
Nuclear factor-κB is upregulated in colorectal cancer
-
Lind DS, Hochwald SN, Malaty J, Rekkas S, Hebig P, Mishra G, et al. Nuclear factor-κB is upregulated in colorectal cancer. Surgery. 2001; 130: 363-369.
-
(2001)
Surgery
, vol.130
, pp. 363-369
-
-
Lind, D.S.1
Hochwald, S.N.2
Malaty, J.3
Rekkas, S.4
Hebig, P.5
Mishra, G.6
-
66
-
-
9744263165
-
Nuclear factor-κB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue
-
Yu LL, Yu HG, Yu JP, Luo HS, Xu XM, Li JH. Nuclear factor-κB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue. World J Gastroenterol. 2004; 10: 3255-3260.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 3255-3260
-
-
Yu, L.L.1
Yu, H.G.2
Yu, J.P.3
Luo, H.S.4
Xu, X.M.5
Li, J.H.6
-
67
-
-
34247496831
-
NF-κB and apoptosis in colorectal tumourigenesis
-
Aranha MM, Borralho PM, Ravasco P, Moreira da Silva IB, Correia L, Fernandes A, et al. NF-κB and apoptosis in colorectal tumourigenesis. Eur J Clin Invest. 2007; 37: 416-424.
-
(2007)
Eur J Clin Invest
, vol.37
, pp. 416-424
-
-
Aranha, M.M.1
Borralho, P.M.2
Ravasco, P.3
Moreira da Silva, I.B.4
Correia, L.5
Fernandes, A.6
-
68
-
-
67649846427
-
Expression of COX-2, NF-κB-p65, NF-κB-p50 and IKKα in malignant and adjacent normal human colorectal tissue
-
Charalambous MP, Lightfoot T, Speirs V, Horgan K, Gooderham NJ. Expression of COX-2, NF-κB-p65, NF-κB-p50 and IKKα in malignant and adjacent normal human colorectal tissue. Br J Cancer. 2009; 101: 106-115.
-
(2009)
Br J Cancer
, vol.101
, pp. 106-115
-
-
Charalambous, M.P.1
Lightfoot, T.2
Speirs, V.3
Horgan, K.4
Gooderham, N.J.5
-
69
-
-
70350497687
-
Invasion associated up-regulation of nuclear factor κB target genes in colorectal cancer
-
Horst D, Budczies J, Brabletz T, Kirchner T, Hlubek F. Invasion associated up-regulation of nuclear factor κB target genes in colorectal cancer. Cancer. 2009; 115: 4946-4958.
-
(2009)
Cancer
, vol.115
, pp. 4946-4958
-
-
Horst, D.1
Budczies, J.2
Brabletz, T.3
Kirchner, T.4
Hlubek, F.5
-
70
-
-
77956483124
-
Polymorphisms in NFκB, PXR, LXR, and risk of colorectal cancer in a prospective study of Danes
-
Andersen V, Christensen J, Overvad K, Tjønneland A, Vogel U. Polymorphisms in NFκB, PXR, LXR, and risk of colorectal cancer in a prospective study of Danes. BMC Cancer. 2010; 10: 484.
-
(2010)
BMC Cancer
, vol.10
, pp. 484
-
-
Andersen, V.1
Christensen, J.2
Overvad, K.3
Tjønneland, A.4
Vogel, U.5
-
71
-
-
79959692901
-
NFκB1 and NFκBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population
-
Song S, Chen D, Lu J, Liao J, Luo Y, Yang Z, et al. NFκB1 and NFκBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population. PloS ONE. 2011; 6: e21726. doi:10.1371/journal.pone.0021726.
-
(2011)
PloS ONE
, vol.6
-
-
Song, S.1
Chen, D.2
Lu, J.3
Liao, J.4
Luo, Y.5
Yang, Z.6
-
73
-
-
38549107462
-
Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis
-
Scanlan PD, Shanahan F, Clune Y, Collins JK, O'Sullivan GC, O'Riordan M, et al. Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis. Environ Microbiol. 2008; 10: 789-798.
-
(2008)
Environ Microbiol
, vol.10
, pp. 789-798
-
-
Scanlan, P.D.1
Shanahan, F.2
Clune, Y.3
Collins, J.K.4
O'Sullivan, G.C.5
O'Riordan, M.6
-
74
-
-
0031586764
-
Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats
-
Onoue M, Kado S, Sakaitani Y, Uchida K, Morotomi M. Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats. Cancer Lett. 1997; 113: 179-186.
-
(1997)
Cancer Lett
, vol.113
, pp. 179-186
-
-
Onoue, M.1
Kado, S.2
Sakaitani, Y.3
Uchida, K.4
Morotomi, M.5
-
75
-
-
40249087075
-
Colorectal carcinogenesis in germ-free and conventionally reared rats: Different intestinal environments affect the systemic immunity
-
Vannucci L, Stepankova R, Kozakova H, Fiserova A, Rossmann P, Tlaskalova-Hogenova H. Colorectal carcinogenesis in germ-free and conventionally reared rats: different intestinal environments affect the systemic immunity. Int J Oncol. 2008; 32: 609-617.
-
(2008)
Int J Oncol
, vol.32
, pp. 609-617
-
-
Vannucci, L.1
Stepankova, R.2
Kozakova, H.3
Fiserova, A.4
Rossmann, P.5
Tlaskalova-Hogenova, H.6
-
76
-
-
0035300492
-
Increased β-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo
-
Sellin JH, Umar S, Xiao J, Morris AP. Increased β-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo. Cancer Res. 2001; 61: 2899-2906.
-
(2001)
Cancer Res
, vol.61
, pp. 2899-2906
-
-
Sellin, J.H.1
Umar, S.2
Xiao, J.3
Morris, A.P.4
-
77
-
-
23044463653
-
Activation of β-catenin by carcinogenic Helicobacter pylori
-
Franco AT, Israel DA, Washington MK, Krishna U, Fox JG, Rogers AB, et al. Activation of β-catenin by carcinogenic Helicobacter pylori. Proc Natl Acad Sci USA. 2005; 102: 10646-10651.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10646-10651
-
-
Franco, A.T.1
Israel, D.A.2
Washington, M.K.3
Krishna, U.4
Fox, J.G.5
Rogers, A.B.6
-
78
-
-
66449101214
-
Enterotoxigenic Bacteroides fragilis: A rogue among symbiotes
-
Sears CL. Enterotoxigenic Bacteroides fragilis: A rogue among symbiotes. Clin Microbiol Rev. 2009; 22: 349-369.
-
(2009)
Clin Microbiol Rev
, vol.22
, pp. 349-369
-
-
Sears, C.L.1
-
79
-
-
79551571717
-
Microbial dysbiosis in colorectal cancer (CRC) patients
-
doi:10.1371/journal.pone.0016393
-
Sobhani I, Tap J, Roudot-Thoraval F, Roperch JP, Letulle S, Langella P, et al. Microbial dysbiosis in colorectal cancer (CRC) patients. PloS ONE. 2011; 6: e16393. doi:10.1371/journal.pone.0016393.
-
(2011)
PloS ONE
, vol.6
-
-
Sobhani, I.1
Tap, J.2
Roudot-Thoraval, F.3
Roperch, J.P.4
Letulle, S.5
Langella, P.6
-
80
-
-
79952117762
-
Host-bacteria interactions in the intestine: Homeostasis to chronic inflammation
-
Barbosa T, Rescigno M. Host-bacteria interactions in the intestine: Homeostasis to chronic inflammation. WIREs Syst Biol Med. 2010; 2: 80-97.
-
(2010)
WIREs Syst Biol Med
, vol.2
, pp. 80-97
-
-
Barbosa, T.1
Rescigno, M.2
-
81
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun. 2000; 68: 7010-7017.
-
(2000)
Infect Immun
, vol.68
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.K.2
-
82
-
-
77956289824
-
Toll-like receptors in inflammatory bowel diseases: A decade later
-
Cario E. Toll-like receptors in inflammatory bowel diseases: a decade later. Inflamm Bowel Dis. 2010; 16: 1583-1597.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 1583-1597
-
-
Cario, E.1
-
83
-
-
39449127013
-
Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: Upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis
-
Frolova L, Drastich P, Rossmann P, Klimesova K, Tlaskalova-Hogenova H. Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: Upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. J Histochem Cytochem. 2008; 56: 267-274.
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 267-274
-
-
Frolova, L.1
Drastich, P.2
Rossmann, P.3
Klimesova, K.4
Tlaskalova-Hogenova, H.5
-
84
-
-
36549082403
-
Toll-like receptor-4 (TLR4) promotes the development of colitisassociated colorectal tumors
-
Fukata M, Chen A, Vamadevan AS, Cohen J, Breglio K, Krishnareddy S, et al. Toll-like receptor-4 (TLR4) promotes the development of colitisassociated colorectal tumors. Gastroenterology. 2007; 133: 1869-1881.
-
(2007)
Gastroenterology
, vol.133
, pp. 1869-1881
-
-
Fukata, M.1
Chen, A.2
Vamadevan, A.S.3
Cohen, J.4
Breglio, K.5
Krishnareddy, S.6
-
85
-
-
20444432334
-
Toll-like receptors on tumor cells facilitate evasion of immune surveillance
-
Huang B, Zhao J, Li H, He KL, Chen Y, Chen SH, et al. Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res. 2005; 65: 5009-5014.
-
(2005)
Cancer Res
, vol.65
, pp. 5009-5014
-
-
Huang, B.1
Zhao, J.2
Li, H.3
He, K.L.4
Chen, Y.5
Chen, S.H.6
-
86
-
-
33748271299
-
Cox-2 is regulated by toll-like receptor-4 (TLR4) signalling and is important for proliferation and apoptosis in response to intestinal mucosal injury
-
Fukata M, Chen A, Klepper A, Krishnareddy S, Vamadevan AS, Thomas LS, et al. Cox-2 is regulated by toll-like receptor-4 (TLR4) signalling and is important for proliferation and apoptosis in response to intestinal mucosal injury. Gastroenterology. 2006; 131: 862-877.
-
(2006)
Gastroenterology
, vol.131
, pp. 862-877
-
-
Fukata, M.1
Chen, A.2
Klepper, A.3
Krishnareddy, S.4
Vamadevan, A.S.5
Thomas, L.S.6
-
87
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
Fukata M, Michelsen KS, Eri R, Thomas LS, Hu B, Lukasek K, et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol. 2005; 288: G1055-G1065.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
-
-
Fukata, M.1
Michelsen, K.S.2
Eri, R.3
Thomas, L.S.4
Hu, B.5
Lukasek, K.6
-
88
-
-
38649129512
-
Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4
-
doi:10.1371/journal.pone.0000662
-
Heimesaat MM, Fischer A, Siegmund B, Kupz A, Niebergall J, Fuchs D, et al. Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4. PloS ONE. 2007; 2: e662. doi:10.1371/journal.pone.0000662.
-
(2007)
PloS ONE
, vol.2
-
-
Heimesaat, M.M.1
Fischer, A.2
Siegmund, B.3
Kupz, A.4
Niebergall, J.5
Fuchs, D.6
-
89
-
-
48549106083
-
Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer
-
Rhee SH, Im E, Pothoulakis C. Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer. Gastroenterology. 2008; 135: 518-528.
-
(2008)
Gastroenterology
, vol.135
, pp. 518-528
-
-
Rhee, S.H.1
Im, E.2
Pothoulakis, C.3
-
90
-
-
34447296425
-
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
-
Rakoff-Nahoum S, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science. 2007; 317: 124-127.
-
(2007)
Science
, vol.317
, pp. 124-127
-
-
Rakoff-Nahoum, S.1
Medzhitov, R.2
-
91
-
-
57749094105
-
The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis
-
Chen GY, Shaw MH, Redondo G, Núñez G. The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis. Cancer Res. 2008; 68: 10060-10067.
-
(2008)
Cancer Res
, vol.68
, pp. 10060-10067
-
-
Chen, G.Y.1
Shaw, M.H.2
Redondo, G.3
Núñez, G.4
-
92
-
-
78049488908
-
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
-
Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti T-D. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J Immunol. 2010; 185: 4912-4920.
-
(2010)
J Immunol
, vol.185
, pp. 4912-4920
-
-
Zaki, M.H.1
Vogel, P.2
Body-Malapel, M.3
Lamkanfi, M.4
Kanneganti, T.-D.5
-
93
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
Hu B, Elinav E, Huber S, Booth CJ, Strowig T, Jin C, et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc Natl Acad Sci USA. 2010; 107: 21635-21640.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21635-21640
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Booth, C.J.4
Strowig, T.5
Jin, C.6
-
94
-
-
79959540809
-
A functional role for nlrp6 in intestinal inflammation and tumorigenesis
-
Chen GY, Liu M, Wang F, Bertin J, Núñez G. A functional role for nlrp6 in intestinal inflammation and tumorigenesis. J Immunol. 2011; 186: 7187-7194.
-
(2011)
J Immunol
, vol.186
, pp. 7187-7194
-
-
Chen, G.Y.1
Liu, M.2
Wang, F.3
Bertin, J.4
Núñez, G.5
|