메뉴 건너뛰기




Volumn 295, Issue 6, 2008, Pages

Bacterial-mucosal interactions in inflammatory bowel disease - An alliance gone bad

Author keywords

Enteric bacteria; Inflammation; Permeability

Indexed keywords

ADAPTIVE IMMUNITY; ANTIGEN PRESENTING CELL; DENDRITIC CELL; ENTERITIS; EPITHELIUM CELL; GOBLET CELL; HELICOBACTER; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; INTESTINE FLORA; INTESTINE MUCOSA; LIPID RAFT; MICROBIAL COMMUNITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; TIGHT JUNCTION;

EID: 57549101916     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90516.2008     Document Type: Review
Times cited : (88)

References (125)
  • 1
    • 27344455595 scopus 로고    scopus 로고
    • Bacterial penetration of the mucosal barrier by targeting lipid rafts
    • Abraham SN, Duncan MJ, Li G, Zaas D. Bacterial penetration of the mucosal barrier by targeting lipid rafts. J Investig Med 53: 318-321, 2005.
    • (2005) J Investig Med , vol.53 , pp. 318-321
    • Abraham, S.N.1    Duncan, M.J.2    Li, G.3    Zaas, D.4
  • 2
    • 34250378697 scopus 로고    scopus 로고
    • Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
    • An G, Wei B, Xia B, McDaniel JM, Ju T, Cummings RD, Braun J, Xia L. Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med 204: 1417-1429, 2007.
    • (2007) J Exp Med , vol.204 , pp. 1417-1429
    • An, G.1    Wei, B.2    Xia, B.3    McDaniel, J.M.4    Ju, T.5    Cummings, R.D.6    Braun, J.7    Xia, L.8
  • 3
    • 54149114711 scopus 로고    scopus 로고
    • Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line
    • In press
    • Aono S, Hirai Y. Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line. Expl Cell Res. In press.
    • Expl Cell Res
    • Aono, S.1    Hirai, Y.2
  • 4
    • 27644566447 scopus 로고    scopus 로고
    • Biologic therapy for inflammatory bowel disease
    • Ardizzone S, Bianchi PG. Biologic therapy for inflammatory bowel disease. Drugs 65: 2253-2286, 2005.
    • (2005) Drugs , vol.65 , pp. 2253-2286
    • Ardizzone, S.1    Bianchi, P.G.2
  • 5
    • 34249827613 scopus 로고    scopus 로고
    • Recent advances in basic and clinical aspects of inflammatory bowel disease: Which steps in the mucosal inflammation should we block for the treatment of inflammatory bowel disease?
    • Asakura H, Suzuki K, Honma T. Recent advances in basic and clinical aspects of inflammatory bowel disease: which steps in the mucosal inflammation should we block for the treatment of inflammatory bowel disease? World J Gastroenterol 13: 2145-2149, 2007.
    • (2007) World J Gastroenterol , vol.13 , pp. 2145-2149
    • Asakura, H.1    Suzuki, K.2    Honma, T.3
  • 6
    • 0027320315 scopus 로고
    • Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization
    • Audie JP, Janin A, Porchet N, Copin MC, Gosselin B, Aubert JP. Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization. J Histochem Cytochem 41: 1479-1485, 1993.
    • (1993) J Histochem Cytochem , vol.41 , pp. 1479-1485
    • Audie, J.P.1    Janin, A.2    Porchet, N.3    Copin, M.C.4    Gosselin, B.5    Aubert, J.P.6
  • 10
    • 0036709730 scopus 로고    scopus 로고
    • Improvement of the probiotic effect of micro-organisms by their combination with maltodextrins, fructo-oligosaccharides and polyunsaturated fatty acids
    • Bomba A, Nemcová R, Gancarcíková S, Herich R, Guba P, Mudronová D. Improvement of the probiotic effect of micro-organisms by their combination with maltodextrins, fructo-oligosaccharides and polyunsaturated fatty acids. Br J Nutr, 88 Suppl 1: S95-S99, 2002.
    • (2002) Br J Nutr , vol.88 , Issue.SUPPL. 1
    • Bomba, A.1    Nemcová, R.2    Gancarcíková, S.3    Herich, R.4    Guba, P.5    Mudronová, D.6
  • 11
    • 14844311937 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease
    • Brown SJ, Abreu MT. Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease. Curr Opin Drug Discov Devel 8: 160-168, 2005.
    • (2005) Curr Opin Drug Discov Devel , vol.8 , pp. 160-168
    • Brown, S.J.1    Abreu, M.T.2
  • 12
    • 20444481707 scopus 로고    scopus 로고
    • Interferon-γ induces internalization of epithelial tight junction proteins via a macropinocytosis-like process
    • Bruewer M, Utech M, Ivanov AI, Hopkins AM, Parkos CA, Nusrat A. Interferon-γ induces internalization of epithelial tight junction proteins via a macropinocytosis-like process. FASEB J 19: 923-933, 2005.
    • (2005) FASEB J , vol.19 , pp. 923-933
    • Bruewer, M.1    Utech, M.2    Ivanov, A.I.3    Hopkins, A.M.4    Parkos, C.A.5    Nusrat, A.6
  • 14
    • 33748039462 scopus 로고    scopus 로고
    • Symbiotic bacteria direct expression of an intestinal bactericidal lectin
    • Cash HL, Whitham CV, Behrendt CL, Hooper LV. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313: 1126-1130, 2006.
    • (2006) Science , vol.313 , pp. 1126-1130
    • Cash, H.L.1    Whitham, C.V.2    Behrendt, C.L.3    Hooper, L.V.4
  • 15
    • 34547665641 scopus 로고    scopus 로고
    • Direct-fed microbial primalac and salinomycin modulate wholebody and intestinal oxygen consumption and intestinal mucosal cytokine production in the broiler chick
    • Chichlowski M, Croom J, McBride BW, Daniel L, Davis G, Koci MD. Direct-fed microbial primalac and salinomycin modulate wholebody and intestinal oxygen consumption and intestinal mucosal cytokine production in the broiler chick. Poult Sci 86: 1100-1106, 2007.
    • (2007) Poult Sci , vol.86 , pp. 1100-1106
    • Chichlowski, M.1    Croom, J.2    McBride, B.W.3    Daniel, L.4    Davis, G.5    Koci, M.D.6
  • 16
    • 36048940317 scopus 로고    scopus 로고
    • Metabolic and physiological impact of probiotics or direct-fed-microbials on poultry: A brief review of current knowledge
    • Chichlowski M, Croom J, McBride BW, Havenstein GB, Koci MD. Metabolic and physiological impact of probiotics or direct-fed-microbials on poultry: a brief review of current knowledge. Int J Poult Sci 6: 694-704, 2007.
    • (2007) Int J Poult Sci , vol.6 , pp. 694-704
    • Chichlowski, M.1    Croom, J.2    McBride, B.W.3    Havenstein, G.B.4    Koci, M.D.5
  • 17
    • 34547680556 scopus 로고    scopus 로고
    • Microarchitecture and spatial relationship between bacteria and ileal, cecal, and colonic epithelium in chicks fed a direct-fed microbial, PrimaLac, and salinomycin
    • Chichlowski M, Croom WJ, Edens FW, McBride BW, Qiu R, Chiang CC, Daniel LR, Havenstein GB, Koci MD. Microarchitecture and spatial relationship between bacteria and ileal, cecal, and colonic epithelium in chicks fed a direct-fed microbial, PrimaLac, and salinomycin. Poult Sci 86: 1121-1132, 2007.
    • (2007) Poult Sci , vol.86 , pp. 1121-1132
    • Chichlowski, M.1    Croom, W.J.2    Edens, F.W.3    McBride, B.W.4    Qiu, R.5    Chiang, C.C.6    Daniel, L.R.7    Havenstein, G.B.8    Koci, M.D.9
  • 18
    • 56549121232 scopus 로고    scopus 로고
    • Helicobacter typhlonius and H. rodentium differentially affect the severity of colon inflammation and inflammation-associated neoplasia in IL-10-deficient mice
    • In press
    • Chichlowski M, Sharp JM, Vanderford DA, Myles MH, Hale LP. Helicobacter typhlonius and H. rodentium differentially affect the severity of colon inflammation and inflammation-associated neoplasia in IL-10-deficient mice. Comp Med. In press.
    • Comp Med
    • Chichlowski, M.1    Sharp, J.M.2    Vanderford, D.A.3    Myles, M.H.4    Hale, L.P.5
  • 19
    • 2142813761 scopus 로고    scopus 로고
    • A porous defense: The leaky epithelial barrier in intestinal disease
    • Clayburgh DR, Shen L, Turner JR. A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest 84: 282-291, 2004.
    • (2004) Lab Invest , vol.84 , pp. 282-291
    • Clayburgh, D.R.1    Shen, L.2    Turner, J.R.3
  • 20
    • 47649097730 scopus 로고    scopus 로고
    • Specific probiotic strains and their combinations counteract adhesion of Enterobacter sakazakii to intestinal mucus
    • Collado MC, Isolauri E, Salminen S. Specific probiotic strains and their combinations counteract adhesion of Enterobacter sakazakii to intestinal mucus. FEMS Microbiol Lett 285: 58-64, 2008.
    • (2008) FEMS Microbiol Lett , vol.285 , pp. 58-64
    • Collado, M.C.1    Isolauri, E.2    Salminen, S.3
  • 24
    • 0034443286 scopus 로고    scopus 로고
    • Microbial biofilms: From ecology to molecular genetics
    • Davey ME, O'Toole GA. Microbial biofilms: from ecology to molecular genetics. Microbiol Mol Biol Rev 64: 847-867, 2000.
    • (2000) Microbiol Mol Biol Rev , vol.64 , pp. 847-867
    • Davey, M.E.1    O'Toole, G.A.2
  • 25
    • 0029126548 scopus 로고
    • MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach
    • De Bolós C, Garrido M, Real FX. MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach. Gastroenterology 109: 723-734, 1995.
    • (1995) Gastroenterology , vol.109 , pp. 723-734
    • De Bolós, C.1    Garrido, M.2    Real, F.X.3
  • 26
    • 14844349149 scopus 로고    scopus 로고
    • Probiotics ameliorate recurrent th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells
    • Di Giacinto C, Marinaro M, Sanchez M, Strober W, Boirivant M. Probiotics ameliorate recurrent th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells. J Immunol 174: 3237-3246, 2005.
    • (2005) J Immunol , vol.174 , pp. 3237-3246
    • Di Giacinto, C.1    Marinaro, M.2    Sanchez, M.3    Strober, W.4    Boirivant, M.5
  • 28
    • 3042552045 scopus 로고    scopus 로고
    • New developments in experimental models of inflammatory bowel disease
    • Elson CO, Cong Y, Lorenz R, Weaver CT. New developments in experimental models of inflammatory bowel disease. Curr Opin Gastroenterol 20: 360-367, 2004.
    • (2004) Curr Opin Gastroenterol , vol.20 , pp. 360-367
    • Elson, C.O.1    Cong, Y.2    Lorenz, R.3    Weaver, C.T.4
  • 29
    • 0026600307 scopus 로고
    • Identification of two porcine brush border glycoproteins that bind the K88ac adhesin of Escherichia coli and correlation of these glycoproteins with the adhesive phenotype
    • Erickson AK, Willgohs JA, McFarland SY, Benfield DA, Francis DH. Identification of two porcine brush border glycoproteins that bind the K88ac adhesin of Escherichia coli and correlation of these glycoproteins with the adhesive phenotype. Infect Immun 60: 983-988, 1992.
    • (1992) Infect Immun , vol.60 , pp. 983-988
    • Erickson, A.K.1    Willgohs, J.A.2    McFarland, S.Y.3    Benfield, D.A.4    Francis, D.H.5
  • 30
    • 2442495410 scopus 로고    scopus 로고
    • Probiotics and the management of inflammatory bowel disease
    • Fedorak RN, Madsen KL. Probiotics and the management of inflammatory bowel disease. Inflamm Bowel Dis 10: 286-299, 2004.
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 286-299
    • Fedorak, R.N.1    Madsen, K.L.2
  • 32
    • 44849086588 scopus 로고    scopus 로고
    • Intestinal epithelial cell up-regulation of LY6 molecules during colitis results in enhanced chemokine secretion
    • Flanagan K, Modrusan Z, Cornelius J, Chavali A, Kasman Komuves L, Mo L, Diehl L. Intestinal epithelial cell up-regulation of LY6 molecules during colitis results in enhanced chemokine secretion. J Immunol 180: 3874-3881, 2008.
    • (2008) J Immunol , vol.180 , pp. 3874-3881
    • Flanagan, K.1    Modrusan, Z.2    Cornelius, J.3    Chavali, A.4    Kasman Komuves, L.5    Mo, L.6    Diehl, L.7
  • 34
    • 44449099036 scopus 로고    scopus 로고
    • Tight junctions and the modulation of barrier function in disease
    • Forster C. Tight junctions and the modulation of barrier function in disease. Histochem Cell Biol 130: 55-70, 2008.
    • (2008) Histochem Cell Biol , vol.130 , pp. 55-70
    • Forster, C.1
  • 35
    • 0033041980 scopus 로고    scopus 로고
    • A novel urease-negative Helicobacter species associated with colitis and typhlitis in IL-10-deficient mice
    • Fox JG, Gorelick PL, Kullberg MC, Ge Z, Dewhirst FE, Ward JM. A novel urease-negative Helicobacter species associated with colitis and typhlitis in IL-10-deficient mice. Infect Immun 67: 1757-1762, 1999.
    • (1999) Infect Immun , vol.67 , pp. 1757-1762
    • Fox, J.G.1    Gorelick, P.L.2    Kullberg, M.C.3    Ge, Z.4    Dewhirst, F.E.5    Ward, J.M.6
  • 36
    • 0030043414 scopus 로고    scopus 로고
    • Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures
    • Furuse M, Fujimoto K, Sato N, Hirase T, Tsukita S. Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. J Cell Sci 109: 429-435, 1996.
    • (1996) J Cell Sci , vol.109 , pp. 429-435
    • Furuse, M.1    Fujimoto, K.2    Sato, N.3    Hirase, T.4    Tsukita, S.5
  • 37
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse M, Fujita K, Hiiragi T, Fujimoto K, ST. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141: 1539-1550, 1998.
    • (1998) J Cell Biol , vol.141 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.S.4
  • 40
    • 27944447984 scopus 로고    scopus 로고
    • Piroxicam treatment of IL-10-deficient mice enhances colonic epithelial apoptosis and mucosal exposure to intestinal bacteria
    • Hale LP, Gottfried MR, Swidsinski A. Piroxicam treatment of IL-10-deficient mice enhances colonic epithelial apoptosis and mucosal exposure to intestinal bacteria. Inflamm Bowel Dis 11: 1060-1069, 2005.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 1060-1069
    • Hale, L.P.1    Gottfried, M.R.2    Swidsinski, A.3
  • 43
    • 0028972499 scopus 로고
    • Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
    • Hermiston ML, Gordon JI. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270: 1203-1207, 1995.
    • (1995) Science , vol.270 , pp. 1203-1207
    • Hermiston, M.L.1    Gordon, J.I.2
  • 44
    • 0028219482 scopus 로고
    • Enzyme linked immunosorbent assay (ELISA) and immunoprecipitation studies on anti-goblet cell antibody using a mucin producing cell line in patients with inflammatory bowel disease
    • Hibi T, Ohara M, Kobayashi K, Brown WR, Toda K, Takaishi H, Hosoda Y, Hayashi A, Iwao Y, Watanabe M. Enzyme linked immunosorbent assay (ELISA) and immunoprecipitation studies on anti-goblet cell antibody using a mucin producing cell line in patients with inflammatory bowel disease. Gut 35: 224-230, 1994.
    • (1994) Gut , vol.35 , pp. 224-230
    • Hibi, T.1    Ohara, M.2    Kobayashi, K.3    Brown, W.R.4    Toda, K.5    Takaishi, H.6    Hosoda, Y.7    Hayashi, A.8    Iwao, Y.9    Watanabe, M.10
  • 47
    • 0242668278 scopus 로고    scopus 로고
    • An in vitro model for investigating intestinal adhesion of potential dairy propionibacteria probiotic strains using cell line C2BBe1
    • Huang Y, Adams MC. An in vitro model for investigating intestinal adhesion of potential dairy propionibacteria probiotic strains using cell line C2BBe1. Lett Appl Microbiol 36: 213-216, 2003.
    • (2003) Lett Appl Microbiol , vol.36 , pp. 213-216
    • Huang, Y.1    Adams, M.C.2
  • 48
    • 0032539777 scopus 로고    scopus 로고
    • Regulation of tight junction permeability and occludin expression by polyunsaturated fatty acids
    • Jiang WG, Bryce RP, Horrobin DF, Mansel RE. Regulation of tight junction permeability and occludin expression by polyunsaturated fatty acids. Biochem Biophys Res Commun 244: 414-420, 1998.
    • (1998) Biochem Biophys Res Commun , vol.244 , pp. 414-420
    • Jiang, W.G.1    Bryce, R.P.2    Horrobin, D.F.3    Mansel, R.E.4
  • 50
    • 0037245156 scopus 로고    scopus 로고
    • Modification of intestinal flora in the treatment of inflammatory bowel disease
    • Kanauchi O, Mitsuyama K, Araki Y, Andoh A. Modification of intestinal flora in the treatment of inflammatory bowel disease. Curr Pharm Des 9: 333-346, 2003.
    • (2003) Curr Pharm Des , vol.9 , pp. 333-346
    • Kanauchi, O.1    Mitsuyama, K.2    Araki, Y.3    Andoh, A.4
  • 51
    • 0346500443 scopus 로고    scopus 로고
    • Effects of polyunsaturated fatty acids in growth medium on lipid composition and on physicochemical surface properties of lactobacilli
    • Kankaanpaa P, Yang B, Kallio H, Isolauri E, Salminen S. Effects of polyunsaturated fatty acids in growth medium on lipid composition and on physicochemical surface properties of lactobacilli. Appl Environ Microbiol 70: 129-136, 2004.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 129-136
    • Kankaanpaa, P.1    Yang, B.2    Kallio, H.3    Isolauri, E.4    Salminen, S.5
  • 52
    • 34247119640 scopus 로고    scopus 로고
    • Engel J. Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane
    • Kierbel A, Gassama-Diagne A, Rocha C, Radoshevich L, Olson J, Mostov K, Engel J. Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane. J Cell Biol 177: 21-27, 2007.
    • (2007) J Cell Biol , vol.177 , pp. 21-27
    • Kierbel, A.1    Gassama-Diagne, A.2    Rocha, C.3    Radoshevich, L.4    Olson, J.5    Mostov, K.6
  • 53
    • 0141653817 scopus 로고    scopus 로고
    • Inhibition of interferon gamma signaling by the short chain fatty acid butyrate
    • Klampfer L, Huang J, Sasazuki T, Shirasawa S, Augenlicht L. Inhibition of interferon gamma signaling by the short chain fatty acid butyrate. Mol Cancer Res 1: 855-862, 2003.
    • (2003) Mol Cancer Res , vol.1 , pp. 855-862
    • Klampfer, L.1    Huang, J.2    Sasazuki, T.3    Shirasawa, S.4    Augenlicht, L.5
  • 54
    • 0037799912 scopus 로고    scopus 로고
    • Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice
    • Kobayashi M, Kweon MN, Kuwata H, Schreiber RD, Kiyono H, Takeda K, Akira S. Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice. J Clin Invest 111: 1297-1308, 2003.
    • (2003) J Clin Invest , vol.111 , pp. 1297-1308
    • Kobayashi, M.1    Kweon, M.N.2    Kuwata, H.3    Schreiber, R.D.4    Kiyono, H.5    Takeda, K.6    Akira, S.7
  • 55
    • 0037867722 scopus 로고    scopus 로고
    • Bacterial-enterocyte crosstalk: Cellular mechanisms in health and disease
    • Kohler H, McCormick B, Walker W. Bacterial-enterocyte crosstalk: cellular mechanisms in health and disease. J Pediatr Gastroenterol Nutr 36: 175-185, 2003.
    • (2003) J Pediatr Gastroenterol Nutr , vol.36 , pp. 175-185
    • Kohler, H.1    McCormick, B.2    Walker, W.3
  • 58
    • 0026949170 scopus 로고
    • Characteristics of the internalization and intracellular survival of Campylobacter jejuni in human epithelial cell cultures
    • Konkel ME, Hayes SF, Joens LA, Cieplak W. Characteristics of the internalization and intracellular survival of Campylobacter jejuni in human epithelial cell cultures. Microb Pathog 13: 357-370, 1992.
    • (1992) Microb Pathog , vol.13 , pp. 357-370
    • Konkel, M.E.1    Hayes, S.F.2    Joens, L.A.3    Cieplak, W.4
  • 61
    • 40149084454 scopus 로고    scopus 로고
    • Lactic acid bacteria inhibit proinflammatory cytokine expression and bacterial glycosaminoglycan degradation activity in dextran sulfate sodium-induced colitic mice
    • Lee HS, Han SY, Bae EA, Huh CS, Ahn YT, Lee JH, Kim DH. Lactic acid bacteria inhibit proinflammatory cytokine expression and bacterial glycosaminoglycan degradation activity in dextran sulfate sodium-induced colitic mice. Int Immunopharmacol 8: 574-580, 2008.
    • (2008) Int Immunopharmacol , vol.8 , pp. 574-580
    • Lee, H.S.1    Han, S.Y.2    Bae, E.A.3    Huh, C.S.4    Ahn, Y.T.5    Lee, J.H.6    Kim, D.H.7
  • 64
    • 41949113169 scopus 로고    scopus 로고
    • Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer
    • Lönnroth C, Andersson M, Arvidsson A, Nordgren S, Brevinge H, Lagerstedt K, Lundholm K. Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer. Cancer Immun 8: 5, 2008.
    • (2008) Cancer Immun , vol.8 , pp. 5
    • Lönnroth, C.1    Andersson, M.2    Arvidsson, A.3    Nordgren, S.4    Brevinge, H.5    Lagerstedt, K.6    Lundholm, K.7
  • 65
    • 1542618118 scopus 로고    scopus 로고
    • Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
    • Macpherson AJ, Uhr T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 303: 1662-1665, 2004.
    • (2004) Science , vol.303 , pp. 1662-1665
    • Macpherson, A.J.1    Uhr, T.2
  • 69
    • 34249933089 scopus 로고    scopus 로고
    • Altered permeability in inflammatory bowel disease: Pathophysiology and clinical implications
    • Mankertz J, Schulzke JD. Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications. Curr Opin Gastroenterol 23: 379-383, 2007.
    • (2007) Curr Opin Gastroenterol , vol.23 , pp. 379-383
    • Mankertz, J.1    Schulzke, J.D.2
  • 70
    • 33645900573 scopus 로고    scopus 로고
    • Towards understanding molecular modes of probiotic action
    • Marco ML, Pavan S, Kleerebezem M. Towards understanding molecular modes of probiotic action. Curr Opin Biotechnol 17: 204-210, 2006.
    • (2006) Curr Opin Biotechnol , vol.17 , pp. 204-210
    • Marco, M.L.1    Pavan, S.2    Kleerebezem, M.3
  • 71
    • 40149092512 scopus 로고    scopus 로고
    • Inflammatory bowel disease, past, present and future: Lessons from animal models
    • Mizoguchi A, Mizoguchi E. Inflammatory bowel disease, past, present and future: lessons from animal models. J Gastroenterol 43: 1-17, 2008.
    • (2008) J Gastroenterol , vol.43 , pp. 1-17
    • Mizoguchi, A.1    Mizoguchi, E.2
  • 73
    • 34547618602 scopus 로고    scopus 로고
    • Characterization of cecal gene expression in a differentially susceptible mouse model of bacterial-induced inflammatory bowel disease
    • Myles MH, Dieckgraefe BK, Criley JM, Franklin CL. Characterization of cecal gene expression in a differentially susceptible mouse model of bacterial-induced inflammatory bowel disease. Inflamm Bowel Dis 13: 822-836, 2007.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 822-836
    • Myles, M.H.1    Dieckgraefe, B.K.2    Criley, J.M.3    Franklin, C.L.4
  • 76
    • 4444256383 scopus 로고    scopus 로고
    • The role of bacterial infection in the pathogenesis of inflammatory bowel disease
    • Ohkusa T, Nomura T, Sato N. The role of bacterial infection in the pathogenesis of inflammatory bowel disease. Intern Med 43: 534-539, 2004.
    • (2004) Intern Med , vol.43 , pp. 534-539
    • Ohkusa, T.1    Nomura, T.2    Sato, N.3
  • 77
    • 0028263637 scopus 로고
    • Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway
    • Ohmori H, Dohrman AF, Gallup M, Tsuda T, Kai H, Gum JR Jr, Kim YS, Basbaum CB. Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway. J Biol Chem 269: 17833-17840, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 17833-17840
    • Ohmori, H.1    Dohrman, A.F.2    Gallup, M.3    Tsuda, T.4    Kai, H.5    Gum Jr, J.R.6    Kim, Y.S.7    Basbaum, C.B.8
  • 78
    • 1642274741 scopus 로고    scopus 로고
    • Functional modulation of enterocytes by gram-positive and gram-negative microorganisms
    • Otte JM, Podolsky DK. Functional modulation of enterocytes by gram-positive and gram-negative microorganisms. Am J Physiol Gastrointest Liver Physiol 286: G613-G626, 2004.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286
    • Otte, J.M.1    Podolsky, D.K.2
  • 79
    • 0242268532 scopus 로고    scopus 로고
    • Lipid rafts and caveolae as portals for endocytosis: New insights and common mechanisms
    • Parton RG, Richards AA. Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms. Traffic 4: 724-738, 2003.
    • (2003) Traffic , vol.4 , pp. 724-738
    • Parton, R.G.1    Richards, A.A.2
  • 82
    • 0347721125 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha disrupts tight junction assembly
    • Poritz LS, Garver KI, Tilberg AF, Koltun WA. Tumor necrosis factor alpha disrupts tight junction assembly. J Surg Res 116: 14-18, 2004.
    • (2004) J Surg Res , vol.116 , pp. 14-18
    • Poritz, L.S.1    Garver, K.I.2    Tilberg, A.F.3    Koltun, W.A.4
  • 83
    • 33748469912 scopus 로고    scopus 로고
    • Correlation between cyclical epithelial barrier dysfunction and bacterial translocation in the relapses of intestinal inflammation
    • Porras M, Martin MT, Yang PC, Jury J, Perdue MH, Vergara P. Correlation between cyclical epithelial barrier dysfunction and bacterial translocation in the relapses of intestinal inflammation. Inflamm Bowel Dis 12: 843-852, 2006.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 843-852
    • Porras, M.1    Martin, M.T.2    Yang, P.C.3    Jury, J.4    Perdue, M.H.5    Vergara, P.6
  • 85
    • 33747114270 scopus 로고    scopus 로고
    • Role of toll-like receptors in spontaneous commensal-dependent colitis
    • Rakoff-Nahoum S, Hao L, Medzhitov R. Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity 25: 319-329, 2006.
    • (2006) Immunity , vol.25 , pp. 319-329
    • Rakoff-Nahoum, S.1    Hao, L.2    Medzhitov, R.3
  • 86
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118: 229-241, 2004.
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 87
    • 0032499681 scopus 로고    scopus 로고
    • A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
    • Randolph GJ, Beaulieu S, Pope M, Sugawara I, Hoffman L, Steinman RM, Muller WA. A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels. Proc Natl Acad Sci USA 95: 6924-6929, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6924-6929
    • Randolph, G.J.1    Beaulieu, S.2    Pope, M.3    Sugawara, I.4    Hoffman, L.5    Steinman, R.M.6    Muller, W.A.7
  • 89
    • 44949142174 scopus 로고    scopus 로고
    • The pathogenic role of intestinal flora in IBD and colon cancer
    • Rescigno M. The pathogenic role of intestinal flora in IBD and colon cancer. Curr Drug Targets: 395-403, 2008.
    • (2008) Curr Drug Targets , pp. 395-403
    • Rescigno, M.1
  • 91
    • 0024812031 scopus 로고
    • Colonic mucus and mucosal glycoproteins: The key to colitis and cancer?
    • Rhodes JM. Colonic mucus and mucosal glycoproteins: the key to colitis and cancer? Gut 30: 1660-1666, 1989.
    • (1989) Gut , vol.30 , pp. 1660-1666
    • Rhodes, J.M.1
  • 93
    • 0029808626 scopus 로고    scopus 로고
    • Colonization by lactobacilli of piglet small intestinal mucus
    • Rojas M, Conway PL. Colonization by lactobacilli of piglet small intestinal mucus. J Appl Bacteriol 81: 474-480, 1996.
    • (1996) J Appl Bacteriol , vol.81 , pp. 474-480
    • Rojas, M.1    Conway, P.L.2
  • 95
    • 38649115342 scopus 로고    scopus 로고
    • Microbial influences in inflammatory bowel diseases
    • Sartor RB. Microbial influences in inflammatory bowel diseases. Gastroenterology 134: 577-594, 2008.
    • (2008) Gastroenterology , vol.134 , pp. 577-594
    • Sartor, R.B.1
  • 97
    • 44249094435 scopus 로고    scopus 로고
    • Microbial host interactions in IBD: Implications for pathogenesis and therapy
    • Sartor RB, Muehlbauer M. Microbial host interactions in IBD: implications for pathogenesis and therapy. Curr Gastroenterol Rep 9: 497-507, 2007.
    • (2007) Curr Gastroenterol Rep , vol.9 , pp. 497-507
    • Sartor, R.B.1    Muehlbauer, M.2
  • 98
    • 33644746546 scopus 로고    scopus 로고
    • Helicobacter typhlonius was detected in the sex organs of three mouse strains but did not transmit vertically
    • Scavizzi F, Raspa M. Helicobacter typhlonius was detected in the sex organs of three mouse strains but did not transmit vertically. Lab Anim 40: 70-79, 2006.
    • (2006) Lab Anim , vol.40 , pp. 70-79
    • Scavizzi, F.1    Raspa, M.2
  • 100
    • 0036904032 scopus 로고    scopus 로고
    • Neuroimmune and epithelial interactions in intestinal inflammation
    • Sharkey KA, Mawe GM. Neuroimmune and epithelial interactions in intestinal inflammation. Curr Opin Pharmacol 2: 669-677, 2002.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 669-677
    • Sharkey, K.A.1    Mawe, G.M.2
  • 102
    • 46049086230 scopus 로고    scopus 로고
    • Analysis of bacterial bowel communities of IBD patients: What has it revealed?
    • Sokol H, Lay C, Seksik P, Tannock GW. Analysis of bacterial bowel communities of IBD patients: what has it revealed? Inflamm Bowel Dis 14: 858-867, 2008.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 858-867
    • Sokol, H.1    Lay, C.2    Seksik, P.3    Tannock, G.W.4
  • 103
    • 33847381116 scopus 로고    scopus 로고
    • The fundamental basis of inflammatory bowel disease
    • Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 117: 514-521, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 514-521
    • Strober, W.1    Fuss, I.2    Mannon, P.3
  • 106
    • 37449017195 scopus 로고    scopus 로고
    • Bacterial biofilm suppression with antibiotics for ulcerative and indeterminate colitis: Consequences of aggressive treatment
    • Swidsinski A, Loening-Baucke V, Bengmark S, Scholze J, Doerffel Y. Bacterial biofilm suppression with antibiotics for ulcerative and indeterminate colitis: consequences of aggressive treatment. Arch Med Res 39: 198-204, 2008.
    • (2008) Arch Med Res , vol.39 , pp. 198-204
    • Swidsinski, A.1    Loening-Baucke, V.2    Bengmark, S.3    Scholze, J.4    Doerffel, Y.5
  • 107
    • 14844351844 scopus 로고    scopus 로고
    • Spatial organization of bacterial flora in normal and inflamed intestine: A fluorescence in situ hybridization study in mice
    • Swidsinski A, Loening-Baucke V, Lochs H, Hale LP. Spatial organization of bacterial flora in normal and inflamed intestine: a fluorescence in situ hybridization study in mice. World J Gastroenterol 11: 1131-1140, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 1131-1140
    • Swidsinski, A.1    Loening-Baucke, V.2    Lochs, H.3    Hale, L.P.4
  • 109
    • 39649100206 scopus 로고    scopus 로고
    • Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora
    • Swidsinski A, Loening-Baucke V, Vaneechoutte M, Doerffel Y. Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora. Inflamm Bowel Dis 14: 147-161, 2008.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 147-161
    • Swidsinski, A.1    Loening-Baucke, V.2    Vaneechoutte, M.3    Doerffel, Y.4
  • 110
    • 22144476548 scopus 로고    scopus 로고
    • Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease
    • Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H. Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol 43: 3380-3389, 2005.
    • (2005) J Clin Microbiol , vol.43 , pp. 3380-3389
    • Swidsinski, A.1    Weber, J.2    Loening-Baucke, V.3    Hale, L.P.4    Lochs, H.5
  • 112
    • 26244442836 scopus 로고    scopus 로고
    • Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: Myosin II-dependent vacuolarization of the apical plasma membrane
    • Utech M, Ivanov AI, Samarin SN, Bruewer M, Turner JR, Mrsny RJ, Parkos CA, Nusrat A. Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. Mol Biol Cell 16: 5040-5052, 2005.
    • (2005) Mol Biol Cell , vol.16 , pp. 5040-5052
    • Utech, M.1    Ivanov, A.I.2    Samarin, S.N.3    Bruewer, M.4    Turner, J.R.5    Mrsny, R.J.6    Parkos, C.A.7    Nusrat, A.8
  • 114
    • 34250358173 scopus 로고    scopus 로고
    • Pochart P. Patchy distribution of mucosal lesions in ileal Crohn's disease is not linked to differences in the dominant mucosa-associated bacteria: A study using fluorescence in situ hybridization and temporal temperature gradient gel electrophoresis
    • Vasquez N, Mangin I, Lepage P, Seksik P, Duong JP, Blum S, Schiffrin E, Suau A, Allez M, Vernier G, Tréton X, Doré J, Marteau P, Pochart P. Patchy distribution of mucosal lesions in ileal Crohn's disease is not linked to differences in the dominant mucosa-associated bacteria: a study using fluorescence in situ hybridization and temporal temperature gradient gel electrophoresis. Inflamm Bowel Dis 13: 684-692, 2007.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 684-692
    • Vasquez, N.1    Mangin, I.2    Lepage, P.3    Seksik, P.4    Duong, J.P.5    Blum, S.6    Schiffrin, E.7    Suau, A.8    Allez, M.9    Vernier, G.10    Tréton, X.11    Doré, J.12    Marteau, P.13
  • 117
    • 13244298599 scopus 로고    scopus 로고
    • Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
    • Wang F, Graham WV, Wang Y, Witkowski ED, Schwarz BT, Turner JR. Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am J Pathol 166: 409-419, 2005.
    • (2005) Am J Pathol , vol.166 , pp. 409-419
    • Wang, F.1    Graham, W.V.2    Wang, Y.3    Witkowski, E.D.4    Schwarz, B.T.5    Turner, J.R.6
  • 119
    • 34249945094 scopus 로고    scopus 로고
    • Defensins and other antimicrobial peptides in inflammatory bowel disease
    • Wehkamp J, Schmid M, Stange EF. Defensins and other antimicrobial peptides in inflammatory bowel disease. Curr Opin Gastroenterol 23: 370-378, 2007.
    • (2007) Curr Opin Gastroenterol , vol.23 , pp. 370-378
    • Wehkamp, J.1    Schmid, M.2    Stange, E.F.3
  • 121
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427-434, 2007.
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 123
    • 29144525990 scopus 로고    scopus 로고
    • The role of lipid rafts in the pathogenesis of bacterial infections
    • Zaas DW, Duncan M, Rae Wright J, Abraham SN. The role of lipid rafts in the pathogenesis of bacterial infections. Biochim Biophys Acta 1746: 305-313, 2005.
    • (2005) Biochim Biophys Acta , vol.1746 , pp. 305-313
    • Zaas, D.W.1    Duncan, M.2    Rae Wright, J.3    Abraham, S.N.4
  • 124
    • 33845995125 scopus 로고    scopus 로고
    • Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
    • Zeissig S, Burgel N, Gunzel D, Richter J, Mankertz J, Wahnschaffe U, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 56: 61-72, 2007.
    • (2007) Gut , vol.56 , pp. 61-72
    • Zeissig, S.1    Burgel, N.2    Gunzel, D.3    Richter, J.4    Mankertz, J.5    Wahnschaffe, U.6    Kroesen, A.J.7    Zeitz, M.8    Fromm, M.9    Schulzke, J.D.10
  • 125
    • 20044368058 scopus 로고    scopus 로고
    • Natural colonization with helicobacter species and the development of inflammatory bowel disease in interleukin-10-deficient mice
    • Zhang L, Danon SJ, Grehan M, Chan V, Lee A, Mitchell H. Natural colonization with helicobacter species and the development of inflammatory bowel disease in interleukin-10-deficient mice. Helicobacter 10: 223-230, 2005.
    • (2005) Helicobacter , vol.10 , pp. 223-230
    • Zhang, L.1    Danon, S.J.2    Grehan, M.3    Chan, V.4    Lee, A.5    Mitchell, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.