-
1
-
-
17144384836
-
Colon cancer: Molecular pathogenesis and clinical relevance
-
Arnold CN, Blum HE. [Colon cancer: molecular pathogenesis and clinical relevance]. Dtsch Med Wochenschr. 2005; 130:809-811.
-
(2005)
Dtsch Med Wochenschr
, vol.130
, pp. 809-811
-
-
Arnold, C.N.1
Blum, H.E.2
-
2
-
-
0033959520
-
Cancer statistics, 2000
-
Greenlee RT, Murray T, Bolden S, Wingo PA. Cancer statistics, 2000. CA Cancer J Clin. 2000;50:7-33.
-
(2000)
CA Cancer J Clin
, vol.50
, pp. 7-33
-
-
Greenlee, R.T.1
Murray, T.2
Bolden, S.3
Wingo, P.A.4
-
3
-
-
0030975671
-
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC(-/-) colon carcinoma
-
DOI 10.1126/science.275.5307.1784
-
Korinek V, Barker N, Morin PJ, et al. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science. 1997;275:1784-1787. (Pubitemid 27136714)
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
4
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
DOI 10.1126/science.275.5307.1787
-
Morin PJ, Sparks AB, Korinek V, et al. Activation of beta-catenin- Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 1997;275:1787-1790. (Pubitemid 27136715)
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
5
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
DOI 10.1126/science.281.5382.1509
-
He TC, Sparks AB, Rago C, et al. Identification of c-MYC as a target of the APC pathway. Science. 1998;281:1509-1512. (Pubitemid 28425575)
-
(1998)
Science
, vol.281
, Issue.5382
, pp. 1509-1512
-
-
He, T.-C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
Da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
6
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
DOI 10.1038/18884
-
Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 1999;398: 422-426. (Pubitemid 29180374)
-
(1999)
Nature
, vol.398
, Issue.6726
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
7
-
-
0023261211
-
Clonal analysis of human colorectal tumors
-
Fearon ER, Hamilton SR, Vogelstein B. Clonal analysis of human colorectal tumors. Science. 1987;238:193-197. (Pubitemid 17139720)
-
(1987)
Science
, vol.238
, Issue.4824
, pp. 193-197
-
-
Fearon, E.R.1
Hamilton, S.R.2
Vogelstein, B.3
-
8
-
-
0031727409
-
Nuclear overexpression of the oncoprotein beta-Catenin in colorectal cancer is localized predominantly at the invasion front
-
Brabletz T, Jung A, Hermann K, Gunther K, Hohenberger W, Kirchner T. Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front. Pathol Res Pract. 1998;194:701-704. (Pubitemid 28523944)
-
(1998)
Pathology Research and Practice
, vol.194
, Issue.10
, pp. 701-704
-
-
Brabletz, T.1
Jung, A.2
Hermann, K.3
Gunther, K.4
Hohenberger, W.5
Kirchner, T.6
-
9
-
-
0035964349
-
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
-
Brabletz T, Jung A, Reu S, et al. Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci USA. 2001;98:10356-10361.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10356-10361
-
-
Brabletz, T.1
Jung, A.2
Reu, S.3
-
10
-
-
0033810123
-
Patterning and nuclear beta-catenin expression in the colonic adenoma-carcinoma sequence: Analogies with embryonic gastrulation
-
Kirchner T, Brabletz T. Patterning and nuclear beta-catenin expression in the colonic adenoma-carcinoma sequence. Analogies with embryonic gastrulation. Am J Pathol. 2000;157:1113-1121. (Pubitemid 30757933)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.4
, pp. 1113-1121
-
-
Kirchner, T.1
Brabletz, T.2
-
11
-
-
34648813274
-
Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer
-
DOI 10.1002/ijc.22916
-
Hlubek F, Brabletz T, Budczies J, Pfeiffer S, Jung A, Kirchner T. Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer. Int J Cancer. 2007;121: 1941-1948. (Pubitemid 47463156)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.9
, pp. 1941-1948
-
-
Hlubek, F.1
Brabletz, T.2
Budczies, J.3
Pfeiffer, S.4
Jung, A.5
Kirchner, T.6
-
12
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997;336:1066-1071.
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
13
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest. 2001;107:241-246.
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
14
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer. 2002;2:301-310. (Pubitemid 37328783)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.4
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.-W.4
-
15
-
-
4444376712
-
Signaling to NF-kappaB
-
Hayden MS, Ghosh S. Signaling to NF-kappaB. Genes Dev. 2004;18:2195-2224.
-
(2004)
Genes Dev
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
16
-
-
33750432183
-
Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression
-
Basseres DS, Baldwin AS. Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression. Oncogene. 2006;25:6817-6830.
-
(2006)
Oncogene
, vol.25
, pp. 6817-6830
-
-
Basseres, D.S.1
Baldwin, A.S.2
-
17
-
-
34247496831
-
NF-kappaB and apoptosis in colorectal tumourigenesis
-
Aranha MM, Borralho PM, Ravasco P, et al. NF-kappaB and apoptosis in colorectal tumourigenesis. Eur J Clin Invest. 2007;37:416-424.
-
(2007)
Eur J Clin Invest
, vol.37
, pp. 416-424
-
-
Aranha, M.M.1
Borralho, P.M.2
Ravasco, P.3
-
18
-
-
28644448573
-
PPAR-gamma is expressed and NF-kB pathway is activated and correlates positively with COX-2 expression in stromal myofibroblasts surrounding colon adenocarcinomas
-
Vandoros GP, Konstantinopoulos PA, Sotiropoulou-Bonikou G, et al. PPAR-gamma is expressed and NF-kB pathway is activated and correlates positively with COX-2 expression in stromal myofibroblasts surrounding colon adenocarcinomas. J Cancer Res Clin Oncol. 2006;132:76-84.
-
(2006)
J Cancer Res Clin Oncol
, vol.132
, pp. 76-84
-
-
Vandoros, G.P.1
Konstantinopoulos, P.A.2
Sotiropoulou-Bonikou, G.3
-
19
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis- associated cancer
-
Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis- associated cancer. Cell. 2004;118:285-296.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
21
-
-
32444450670
-
-
The R Development Core Team. Available at: Accessed on June 1, 2008
-
The R Development Core Team. The R Foundation for Statistical Computing. Available at: http://www.r-project. org 2008. Accessed on June 1, 2008.
-
(2008)
The R Foundation for Statistical Computing
-
-
-
22
-
-
0035829361
-
Controlling the false discovery rate in behavior genetics research
-
DOI 10.1016/S0166-4328(01)00297-2, PII S0166432801002972
-
Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I. Controlling the false discovery rate in behavior genetics research. Behav Brain Res. 2001;125:279-284. (Pubitemid 33000466)
-
(2001)
Behavioural Brain Research
, vol.125
, Issue.1-2
, pp. 279-284
-
-
Benjamini, Y.1
Drai, D.2
Elmer, G.3
Kafkafi, N.4
Golani, I.5
-
23
-
-
0029384013
-
Expression of tenascin in tumors of the esophagus, small intestine and colorectum. An immunohistochemical study
-
Broll R, Meyer S, Neuber M, Bruch HP. Expression of tenascin in tumors of the esophagus, small intestine and colorectum. An immunohistochemical study. Gen Diagn Pathol. 1995;141:111-119.
-
(1995)
Gen Diagn Pathol
, vol.141
, pp. 111-119
-
-
Broll, R.1
Meyer, S.2
Neuber, M.3
Bruch, H.P.4
-
24
-
-
0037659646
-
The Re1/NF-kappa B/I kappa B signal transduction pathway and cancer
-
Gilmore TD. The Re1/NF-kappa B/I kappa B signal transduction pathway and cancer. Cancer Treat Res. 2003;115: 241-265.
-
(2003)
Cancer Treat Res
, vol.115
, pp. 241-265
-
-
Gilmore, T.D.1
-
25
-
-
0035902141
-
The microenvironment of the tumour-host interface
-
Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature. 2001;411:375-379.
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.A.1
Kohn, E.C.2
-
26
-
-
3042656476
-
Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect - A histopathological and immunohistochemical study
-
serial online
-
Nagtegaal ID, Marijnen CA, Kranenbarg EK, et al. Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect - a histopathological and immunohistochemical study [serial online]. BMC Cancer. 2001;1:7.
-
(2001)
BMC Cancer
, vol.1
, pp. 7
-
-
Nagtegaal, I.D.1
Marijnen, C.A.2
Kranenbarg, E.K.3
-
27
-
-
1442352120
-
Divergent C-terminal transactivation domains of Rel/NF-kappa B proteins are critical determinants of their oncogenic potential in lymphocytes
-
Fan Y, Rayet B, Gelinas C. Divergent C-terminal transactivation domains of Rel/NF-kappa B proteins are critical determinants of their oncogenic potential in lymphocytes. Oncogene. 2004;23:1030-1042.
-
(2004)
Oncogene
, vol.23
, pp. 1030-1042
-
-
Fan, Y.1
Rayet, B.2
Gelinas, C.3
-
28
-
-
0035950554
-
Malignant transformation of primary chicken spleen cells by human transcription factor c-Rel
-
Gilmore TD, Cormier C, Jean-Jacques J, Gapuzan ME. Malignant transformation of primary chicken spleen cells by human transcription factor c-Rel. Oncogene. 2001;20: 7098-7103.
-
(2001)
Oncogene
, vol.20
, pp. 7098-7103
-
-
Gilmore, T.D.1
Cormier, C.2
Jean-Jacques, J.3
Gapuzan, M.E.4
-
29
-
-
0028345720
-
Transformation of avian fibroblasts overexpressing the c-rel proto- Oncogene and a variant of c-rel lacking 40 C-terminal amino acids
-
Kralova J, Schatzle JD, Bargmann W, Bose HR Jr. Transformation of avian fibroblasts overexpressing the c-rel proto-oncogene and a variant of c-rel lacking 40 C-terminal amino acids. J Virol. 1994;68:2073-2083. (Pubitemid 24091883)
-
(1994)
Journal of Virology
, vol.68
, Issue.4
, pp. 2073-2083
-
-
Kralova, J.1
Schatzle, J.D.2
Bargmann, W.3
Bose Jr., H.R.4
-
30
-
-
0028209815
-
Evolution of the oncogenic potential of v-rel: Rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformation
-
Nehyba J, Hrdlickova R, Humphries EH. Evolution of the oncogenic potential of v-rel: rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformation. J Virol. 1994;68:2039-2050. (Pubitemid 24091879)
-
(1994)
Journal of Virology
, vol.68
, Issue.4
, pp. 2039-2050
-
-
Nehyba, J.1
Hrdlickova, R.2
Humphries, E.H.3
-
31
-
-
36349034540
-
Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment
-
DOI 10.2353/ajpath.2007.060661
-
Mueller L, Goumas FA, Affeldt M, et al. Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment. Am J Pathol. 2007;171:1608-1618. (Pubitemid 350158321)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.5
, pp. 1608-1618
-
-
Mueller, L.1
Goumas, F.A.2
Affeldt, M.3
Sandtner, S.4
Gehling, U.M.5
Brilloff, S.6
Walter, J.7
Karnatz, N.8
Lamszus, K.9
Rogiers, X.10
Broering, D.C.11
-
32
-
-
0034254445
-
The influence of the microenvironment on the malignant phenotype
-
Park CC, Bissell MJ, Barcellos-Hoff MH. The influence of the microenvironment on the malignant phenotype. Mol Med Today. 2000;6:324-329.
-
(2000)
Mol Med Today
, vol.6
, pp. 324-329
-
-
Park, C.C.1
Bissell, M.J.2
Barcellos-Hoff, M.H.3
-
33
-
-
33748756170
-
IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation
-
DOI 10.1074/jbc.M603133200
-
Adli M, Baldwin AS. IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation. J Biol Chem. 2006;281:26976-26984. (Pubitemid 44401726)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.37
, pp. 26976-26984
-
-
Adli, M.1
Baldwin, A.S.2
-
34
-
-
0034708132
-
Selective activation of NF-kappa B subunits in human breast cancer: Potential roles for NF-kappa B2/p52 and for Bcl-3
-
Cogswell PC, Guttridge DC, Funkhouser WK, Baldwin AS Jr. Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene. 2000;19:1123-1131.
-
(2000)
Oncogene
, vol.19
, pp. 1123-1131
-
-
Cogswell, P.C.1
Guttridge, D.C.2
Funkhouser, W.K.3
Baldwin Jr., A.S.4
-
35
-
-
0041631005
-
Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors
-
DOI 10.1128/MCB.23.16.5738-5754.2003
-
Romieu-Mourez R, Kim DW, Shin SM, et al. Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors. Mol Cell Biol. 2003;23:5738-5754. (Pubitemid 36951337)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.16
, pp. 5738-5754
-
-
Romieu-Mourez, R.1
Kim, D.W.2
Shin, S.M.3
Demicco, E.G.4
Landesman-Bollag, E.5
Seldin, D.C.6
Cardiff, R.D.7
Sonenshein, G.E.8
-
36
-
-
0034682072
-
Roles for Msx and Dlx homeoproteins in vertebrate development
-
DOI 10.1016/S0378-1119(00)00081-0, PII S0378111900000810
-
Bendall AJ, Abate-Shen C. Roles for Msx and Dlx homeoproteins in vertebrate development. Gene. 2000;247:17-31. (Pubitemid 30201557)
-
(2000)
Gene
, vol.247
, Issue.1-2
, pp. 17-31
-
-
Bendall, A.J.1
Abate-Shen, C.2
-
37
-
-
33750741945
-
GROalpha is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1
-
Wen Y, Giardina SF, Hamming D, et al. GROalpha is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1. Clin Cancer Res. 2006;12(20 pt 1):5951-5959.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.20 PART 1
, pp. 5951-5959
-
-
Wen, Y.1
Giardina, S.F.2
Hamming, D.3
-
38
-
-
33645850713
-
CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer
-
Wang D, Wang H, Brown J, et al. CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. J Exp Med. 2006;203:941-951.
-
(2006)
J Exp Med
, vol.203
, pp. 941-951
-
-
Wang, D.1
Wang, H.2
Brown, J.3
-
39
-
-
23944469303
-
Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma
-
Musha H, Ohtani H, Mizoi T, et al. Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma. Int J Cancer. 2005;116:949-956.
-
(2005)
Int J Cancer
, vol.116
, pp. 949-956
-
-
Musha, H.1
Ohtani, H.2
Mizoi, T.3
-
40
-
-
41549105427
-
Prognostic significance of expression of CCL5/RANTES receptors in patients with gastric cancer
-
Sugasawa H, Ichikura T, Tsujimoto H, et al. Prognostic significance of expression of CCL5/RANTES receptors in patients with gastric cancer. J Surg Oncol. 2008;97:445-450.
-
(2008)
J Surg Oncol
, vol.97
, pp. 445-450
-
-
Sugasawa, H.1
Ichikura, T.2
Tsujimoto, H.3
-
41
-
-
28744442905
-
Beta-catenin regulates the expression of tenascin-C in human colorectal tumors
-
Beiter K, Hiendlmeyer E, Brabletz T, et al. Beta-catenin regulates the expression of tenascin-C in human colorectal tumors. Oncogene. 2005;24:8200-8204.
-
(2005)
Oncogene
, vol.24
, pp. 8200-8204
-
-
Beiter, K.1
Hiendlmeyer, E.2
Brabletz, T.3
-
42
-
-
0035165350
-
Thrombospondin-1 and -2 messenger RNA expression in epithelial ovarian tumor
-
Kodama J, Hashimoto I, Seki N, et al. Thrombospondin-1 and -2 messenger RNA expression in epithelial ovarian tumor. Anticancer Res. 2001;21:2983-2987.
-
(2001)
Anticancer Res
, vol.21
, pp. 2983-2987
-
-
Kodama, J.1
Hashimoto, I.2
Seki, N.3
-
43
-
-
0035433111
-
Thrombospondin-1 and -2 messenger RNA expression in normal and neoplastic endometrial tissues: Correlation with angiogenesis and prognosis
-
Seki N, Kodama J, Hashimoto I, Hongo A, Yoshinouchi M, Kudo T. Thrombospondin-1 and -2 messenger RNA expression in normal and neoplastic endometrial tissues: correlation with angiogenesis and prognosis. Int J Oncol. 2001;19:305-310.
-
(2001)
Int J Oncol
, vol.19
, pp. 305-310
-
-
Seki, N.1
Kodama, J.2
Hashimoto, I.3
Hongo, A.4
Yoshinouchi, M.5
Kudo, T.6
-
44
-
-
40849114627
-
Oncogenic rasinduced expression of cytokines: A new target of anti-cancer therapeutics
-
Ancrile BB, O'Hayer KM, Counter CM. Oncogenic rasinduced expression of cytokines: a new target of anti-cancer therapeutics. Mol Interv. 2008;8:22-27.
-
(2008)
Mol Interv
, vol.8
, pp. 22-27
-
-
Ancrile, B.B.1
O'Hayer, K.M.2
Counter, C.M.3
-
45
-
-
58349102939
-
Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas
-
Sivasankaran B, Degen M, Ghaffari A, et al. Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas. Cancer Res. 2009;69:458-465.
-
(2009)
Cancer Res
, vol.69
, pp. 458-465
-
-
Sivasankaran, B.1
Degen, M.2
Ghaffari, A.3
-
46
-
-
0142254155
-
A transcriptional response to Wnt protein in human embryonic carcinoma cells
-
serial online
-
Willert J, Epping M, Pollack JR, Brown PO, Nusse R. A transcriptional response to Wnt protein in human embryonic carcinoma cells [serial online]. BMC Dev Biol. 2002;2:8.
-
(2002)
BMC Dev Biol
, vol.2
, pp. 8
-
-
Willert, J.1
Epping, M.2
Pollack, J.R.3
Brown, P.O.4
Nusse, R.5
-
47
-
-
33847188791
-
NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer
-
DOI 10.2174/092986707779941113
-
Calzado MA, Bacher S, Schmitz ML. NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer. Curr Med Chem. 2007;14:367-376. (Pubitemid 46299703)
-
(2007)
Current Medicinal Chemistry
, vol.14
, Issue.3
, pp. 367-376
-
-
Calzado, M.A.1
Bacher, S.2
Schmitz, M.L.3
|