Amyloid-like fibril formation by polyq proteins: A critical balance between the polyq length and the constraints imposed by the host protein

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Scarafone, Natacha ^a   Pain, Coralie ^a   Fratamico, Anthony ^a   Gaspard, Gilles ^a,b   Yilmaz, Nursel ^a   Filée, Patrice ^a   Galleni, Moreno ^a   Matagne, André ^a   Dumoulin, Mireille ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b ProGenosis SA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PROTEIN; BETA LACTAMASE; CHIMERIC PROTEIN; POLYGLUTAMINE; AMYLOID; HYBRID PROTEIN; PEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN STABILITY; PROTEIN UNFOLDING; RESIDUE ANALYSIS; AMINO ACID SEQUENCE; BACILLUS; CHEMICAL STRUCTURE; CHEMISTRY; DEGENERATIVE DISEASE; ENZYME STABILITY; ENZYMOLOGY; GENETICS; HUMAN; IN VITRO STUDY; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN DENATURATION; PROTEIN MULTIMERIZATION; THERMODYNAMICS; TRANSMISSION ELECTRON MICROSCOPY; TRINUCLEOTIDE REPEAT; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; AMYLOID; BACILLUS; BETA-LACTAMASES; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; HUMANS; KINETICS; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEURODEGENERATIVE DISEASES; PEPTIDES; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN MULTIMERIZATION; RECOMBINANT FUSION PROTEINS; THERMODYNAMICS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84857936144     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031253     Document Type: Article

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