A strategy for generating polyglutamine 'length libraries' in model host proteins

Protein Engineering, Design and Selection

Volumn 21, Issue 3, 2008, Pages 161-164

  Tobelmann, Matthew D ^a   Kerby, Robert L ^b   Murphy, Regina M ^a  

^a Wisconsin Electric Machines and Power Electronics Consortium   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Aggregation; Misfolding; Polyglutamine; Recombination

Indexed keywords

DISEASES; GENETIC ENGINEERING; MATHEMATICAL MODELS; NEUROLOGY;

MODEL HOST PROTEINS; POLYGLUTAMINE (POLYQ);

PROTEINS;

POLYGLUTAMINE;

ARTICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN PURIFICATION;

HUNTINGTON DISEASE; MYOGLOBIN; PEPTIDES; PROTEIN FOLDING; RECOMBINANT PROTEINS;

EID: 40049092914     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzm078     Document Type: Article

References (30)

1. Bevivino,A.E. and Loll,P.J. (2001) Proc. Natl Acad. Sci. USA, 98, 11955-11960.
2. Bhattacharyya,A.M., Thakur,A.K. and Wetzel,R. (2005) Proc. Natl Acad. Sci. USA, 103, 15400-15405.
3. Chen,Y.W., Stott,K. and Perutz,M.F. (1999) Proc. Natl Acad. Sci. USA, 96, 1257-1261.
4. Chow,M.K.M., Ellisdon,A.M., Cabrita,L.D. and Bottomley,S.P. (2004) J. Biol. Chem., 279, 47643-47651.
5. Gandhi,S. and Wood,N.W. (1999) Hum. Mol. Genet., 14, 2749-2755.
6. Gusella,J.F. and MacDonald,M.E. (2000) Nat. Rev. Neurosci., 1, 109-115.
7. Gusella,J.F. and MacDonald,M.E. (2006) Trends Biochem. Sci., 31, 533-540.
8. Jakupciak,J.P. and Wells,R.D. (1999) J. Biol. Chem., 274, 23468-23479.
9. Kim,S.-H., Cai,L., Pytlos,M.J., Edwards,S.F. and Sinden,R.R. (2005) BioTechniques, 38, 247-253.
10. Klein,F.A.C., Pastore,A., Masino,L., Zeder-Lutz,G., Nierengarten,H., Oulad-Abdeighani,M. and Altschuh,D. (2007) J. Mol. Biol., 371, 235-244.
11. Laccone,F., Maiwald,R. and Bingemann,S. (1999) Hum. Mutat., 13, 497-502.
12. Lee,C.C., Walters,R.H. and Murphy,R.M. Biochem., 46, 12810-12820.
13. Lichtenthaler,S.F., Beher,D., Grimm,H.S., Wang,R., Shearman,M.S. and Masters,C.L. (2002) Proc. Natl Acad. Sci. USA, 99, 1365-1370.
14. Masino,L., Kelly,G., Leonard,K., Trottier,Y. and Pastore,A. (2002) FEBS Lett., 513, 267-272.
15. Masino,L., Musi,V., Menon,R.P., Fusi,P., Kelly,G., Frenkiel,T.A., Trottier,Y. and Pastore,A. (2003) FEBS Lett., 549, 21-25.
16. Michalik,A., Kazantsev,A. and Van Broeckhoven,C. (2001) BioTechniques, 31, 250-254.
17. Ohshima,K., Kang,S. and Wells,R.D. (1996) J. Biol. Chem., 271, 1853-1856.
18. Ordway,J.M. and Detloff,P.J. (1996) BioTechniques, 21, 609-612.
19. Ordway,J.M., TallaksenGreene,S., Gutekunst,C.A., Bernstein,E.M., Cearley,J.A., Wiener,H.W., Dure,L.S., Linsey,R., Hersch,S.M., Jope,R.S., et al. (1997) Cell, 91, 753-763.
20. Peters,M.F. and Ross,C.A. (1999) Neurosci. Lett., 275, 129-132.
21. Poirier,M.A., Jiang,H. and Ross,C.A. (2005) Hum. Mol. Genet, 14, 765-774.
22. Prusiner,S.B., Scott,M.R., DeArmond,S.J. and Cohen,F.E. (1998) Cell, 93, 337-348.
23. Rich,T. and Varadaraj,A. (2007) PLoS One, 2, e1014. doi:10.1371/journal.pone.0001014.
24. Sasagawa,N. and Ishiura,S. (2006) Anal. Biochem., 357, 308-310.
25. Scherzinger,E., Schweiger,K., Lurz,R., Lehrach,H. and Wanker,E.E. (1999) Phil. Trans. Royal Soc. Lond. B Biol. Sci., 354, 991-994.
26. Shehi,E., Fusi,P., Secundo,F., Pozzuolo,S., Bairati,A. and Tortora,P. (2003) Biochemistry, 42, 14626-14632.
27. Takahashi,N., Sasagawa,N., Suzuki,K. and Ishiura,S. (1999) Neurosci. Lett., 262, 45-48.
28. Tanaka,M., Morishima,I., Akagi,T., Hashikawa,T. and Nukina,N. (2001) J. Biol. Chem., 276, 45470-45475.
29. Wacker,J.L., Zareie,M.H., Fong,H., Sarikaya,M. and Muchowski,P.J. (2004) Nat. Struct. Mol. Biol., 11, 1215-1222.
30. Wanker,E.E. (2000) Biol. Chem., 381, 937-942.