메뉴 건너뛰기




Volumn 37, Issue 1, 2012, Pages 41-49

The genetic association of DUSP6 with bipolar disorder and its effect on ERK activity

Author keywords

Bipolar disorder; Dual specificity phosphatase 6; Genetic association; Leu114Val polymorphism; Ser144Ala polymorphism

Indexed keywords

ALANINE; LEUCINE; LITHIUM CHLORIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SERINE; VALINE;

EID: 84857786209     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2011.11.014     Document Type: Article
Times cited : (24)

References (89)
  • 2
    • 73049086521 scopus 로고    scopus 로고
    • FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway
    • Aragon F., Pujades C. FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway. BMC Developmental Biology 2009, 9:61.
    • (2009) BMC Developmental Biology , vol.9 , pp. 61
    • Aragon, F.1    Pujades, C.2
  • 3
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 4
    • 0037047611 scopus 로고    scopus 로고
    • MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
    • Bhalla U.S., Ram P.T., Iyengar R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 2002, 297:1018-1023.
    • (2002) Science , vol.297 , pp. 1018-1023
    • Bhalla, U.S.1    Ram, P.T.2    Iyengar, R.3
  • 5
    • 0015817744 scopus 로고
    • Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture
    • Biedler J.L., Helson L., Spengler B.A. Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Research 1973, 33:2643-2652.
    • (1973) Cancer Research , vol.33 , pp. 2643-2652
    • Biedler, J.L.1    Helson, L.2    Spengler, B.A.3
  • 7
    • 1342269034 scopus 로고    scopus 로고
    • Special considerations in treating bipolar disorder in women
    • Burt V.K., Rasgon N. Special considerations in treating bipolar disorder in women. Bipolar Disorders 2004, 6:2-13.
    • (2004) Bipolar Disorders , vol.6 , pp. 2-13
    • Burt, V.K.1    Rasgon, N.2
  • 8
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: a gene family for control of MAP kinase function
    • Camps M., Nichols A., Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. The FASEB Journal 2000, 14:6-16.
    • (2000) The FASEB Journal , vol.14 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 9
    • 0032557632 scopus 로고    scopus 로고
    • Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase
    • Camps M., Nichols A., Gillieron C., Antonsson B., Muda M., Chabert C., et al. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase. Science 1998, 280:1262-1265.
    • (1998) Science , vol.280 , pp. 1262-1265
    • Camps, M.1    Nichols, A.2    Gillieron, C.3    Antonsson, B.4    Muda, M.5    Chabert, C.6
  • 10
    • 33846560734 scopus 로고    scopus 로고
    • Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability
    • Carter C.J. Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability. Neurochemistry International 2007, 50:461-490.
    • (2007) Neurochemistry International , vol.50 , pp. 461-490
    • Carter, C.J.1
  • 11
    • 33748156957 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway: an emerging promising target for mood stabilizers
    • Chen G., Manji H.K. The extracellular signal-regulated kinase pathway: an emerging promising target for mood stabilizers. Current Opinion in Psychiatry 2006, 19:313-323.
    • (2006) Current Opinion in Psychiatry , vol.19 , pp. 313-323
    • Chen, G.1    Manji, H.K.2
  • 12
    • 33745241078 scopus 로고    scopus 로고
    • Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance
    • Cui Y., Parra I., Zhang M., Hilsenbeck S.G., Tsimelzon A., Furukawa T., et al. Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance. Cancer Research 2006, 66:5950-5959.
    • (2006) Cancer Research , vol.66 , pp. 5950-5959
    • Cui, Y.1    Parra, I.2    Zhang, M.3    Hilsenbeck, S.G.4    Tsimelzon, A.5    Furukawa, T.6
  • 13
    • 12444256025 scopus 로고    scopus 로고
    • Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q
    • Curtis D., Kalsi G., Brynjolfsson J., McInnis M., O'Neill J., Smyth C., et al. Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q. Psychiatric Genetics 2003, 13:77-84.
    • (2003) Psychiatric Genetics , vol.13 , pp. 77-84
    • Curtis, D.1    Kalsi, G.2    Brynjolfsson, J.3    McInnis, M.4    O'Neill, J.5    Smyth, C.6
  • 14
    • 0028965001 scopus 로고
    • Linkage studies of bipolar disorder in the region of the Darier's disease gene on chromosome 12q23-24.1
    • Dawson E., Parfitt E., Roberts Q., Daniels J., Lim L., Sham P., et al. Linkage studies of bipolar disorder in the region of the Darier's disease gene on chromosome 12q23-24.1. American Journal of Medical Genetics 1995, 60:94-102.
    • (1995) American Journal of Medical Genetics , vol.60 , pp. 94-102
    • Dawson, E.1    Parfitt, E.2    Roberts, Q.3    Daniels, J.4    Lim, L.5    Sham, P.6
  • 16
    • 13644254946 scopus 로고    scopus 로고
    • Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons
    • Di Daniel E., Mudge A.W., Maycox P.R. Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons. Bipolar Disorders 2005, 7:33-41.
    • (2005) Bipolar Disorders , vol.7 , pp. 33-41
    • Di Daniel, E.1    Mudge, A.W.2    Maycox, P.R.3
  • 17
    • 0036228105 scopus 로고    scopus 로고
    • Expression of the ERK-specific MAP kinase phosphatase PYST1/MKP3 in mouse embryos during morphogenesis and early organogenesis
    • Dickinson R.J., Eblaghie M.C., Keyse S.M., Morriss-Kay G.M. Expression of the ERK-specific MAP kinase phosphatase PYST1/MKP3 in mouse embryos during morphogenesis and early organogenesis. Mechanisms of Development 2002, 113:193-196.
    • (2002) Mechanisms of Development , vol.113 , pp. 193-196
    • Dickinson, R.J.1    Eblaghie, M.C.2    Keyse, S.M.3    Morriss-Kay, G.M.4
  • 18
    • 78449250771 scopus 로고    scopus 로고
    • Valproate induces DNA demethylation in nuclear extracts from adult mouse brain
    • Dong E., Chen Y., Gavin D.P., Grayson D.R., Guidotti A. Valproate induces DNA demethylation in nuclear extracts from adult mouse brain. Epigenetics 2010, 5.
    • (2010) Epigenetics , vol.5
    • Dong, E.1    Chen, Y.2    Gavin, D.P.3    Grayson, D.R.4    Guidotti, A.5
  • 20
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Human Heredity 2008, 66:87-98.
    • (2008) Human Heredity , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 21
    • 33847308098 scopus 로고    scopus 로고
    • A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment
    • Duman C.H., Schlesinger L., Kodama M., Russell D.S., Duman R.S. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biological Psychiatry 2007, 61:661-670.
    • (2007) Biological Psychiatry , vol.61 , pp. 661-670
    • Duman, C.H.1    Schlesinger, L.2    Kodama, M.3    Russell, D.S.4    Duman, R.S.5
  • 22
    • 4243141885 scopus 로고    scopus 로고
    • Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos
    • Eblaghie M.C., Song S.J., Kim J.Y., Akita K., Tickle C., Jung H.S. Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos. Journal of Anatomy 2004, 205:1-13.
    • (2004) Journal of Anatomy , vol.205 , pp. 1-13
    • Eblaghie, M.C.1    Song, S.J.2    Kim, J.Y.3    Akita, K.4    Tickle, C.5    Jung, H.S.6
  • 24
    • 0043240266 scopus 로고    scopus 로고
    • The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
    • Einat H., Yuan P., Gould T.D., Li J., Du J., Zhang L., et al. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. Journal of Neuroscience 2003, 23:7311-7316.
    • (2003) Journal of Neuroscience , vol.23 , pp. 7311-7316
    • Einat, H.1    Yuan, P.2    Gould, T.D.3    Li, J.4    Du, J.5    Zhang, L.6
  • 26
    • 0242475154 scopus 로고    scopus 로고
    • Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau
    • Ghribi O., Prammonjago P., Herman M.M., Spaulding N.K., Savory J. Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau. Brain Research. Molecular Brain Research 2003, 119:201-206.
    • (2003) Brain Research. Molecular Brain Research , vol.119 , pp. 201-206
    • Ghribi, O.1    Prammonjago, P.2    Herman, M.M.3    Spaulding, N.K.4    Savory, J.5
  • 28
    • 79958144482 scopus 로고    scopus 로고
    • Gender differences in prepulse inhibition (PPI) in bipolar disorder: men have reduced PPI, women have increased PPI
    • Gogos A., van den Buuse M., Rossell S. Gender differences in prepulse inhibition (PPI) in bipolar disorder: men have reduced PPI, women have increased PPI. The International Journal of Neuropsychopharmacology 2009, 12:1249-1259.
    • (2009) The International Journal of Neuropsychopharmacology , vol.12 , pp. 1249-1259
    • Gogos, A.1    van den Buuse, M.2    Rossell, S.3
  • 29
    • 42449157505 scopus 로고    scopus 로고
    • Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways
    • Goldbeter A., Pourquie O. Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways. Journal of Theoretical Biology 2008, 252:574-585.
    • (2008) Journal of Theoretical Biology , vol.252 , pp. 574-585
    • Goldbeter, A.1    Pourquie, O.2
  • 30
    • 0029905354 scopus 로고    scopus 로고
    • Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase
    • Groom L.A., Sneddon A.A., Alessi D.R., Dowd S., Keyse S.M. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO Journal 1996, 15:3621-3632.
    • (1996) EMBO Journal , vol.15 , pp. 3621-3632
    • Groom, L.A.1    Sneddon, A.A.2    Alessi, D.R.3    Dowd, S.4    Keyse, S.M.5
  • 31
    • 3242788185 scopus 로고    scopus 로고
    • Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
    • Hao Y., Creson T., Zhang L., Li P., Du F., Yuan P., et al. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. Journal of Neuroscience 2004, 24:6590-6599.
    • (2004) Journal of Neuroscience , vol.24 , pp. 6590-6599
    • Hao, Y.1    Creson, T.2    Zhang, L.3    Li, P.4    Du, F.5    Yuan, P.6
  • 33
    • 34248210189 scopus 로고    scopus 로고
    • Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses
    • Jeffrey K.L., Camps M., Rommel C., Mackay C.R. Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nature Reviews. Drug Discovery 2007, 6:391-403.
    • (2007) Nature Reviews. Drug Discovery , vol.6 , pp. 391-403
    • Jeffrey, K.L.1    Camps, M.2    Rommel, C.3    Mackay, C.R.4
  • 34
    • 85047697286 scopus 로고    scopus 로고
    • Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease
    • Jones I., Jacobsen N., Green E.K., Elvidge G.P., Owen M.J., Craddock N. Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease. Molecular Psychiatry 2002, 7:424-427.
    • (2002) Molecular Psychiatry , vol.7 , pp. 424-427
    • Jones, I.1    Jacobsen, N.2    Green, E.K.3    Elvidge, G.P.4    Owen, M.J.5    Craddock, N.6
  • 35
    • 2442719071 scopus 로고    scopus 로고
    • Korean version of the diagnostic interview for genetic studies: validity and reliability
    • Joo E.J., Joo Y.H., Hong J.P., Hwang S., Maeng S.J., Han J.H., et al. Korean version of the diagnostic interview for genetic studies: validity and reliability. Comprehensive Psychiatry 2004, 45:225-229.
    • (2004) Comprehensive Psychiatry , vol.45 , pp. 225-229
    • Joo, E.J.1    Joo, Y.H.2    Hong, J.P.3    Hwang, S.4    Maeng, S.J.5    Han, J.H.6
  • 36
    • 4744365623 scopus 로고    scopus 로고
    • Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal
    • Karlsson M., Mathers J., Dickinson R.J., Mandl M., Keyse S.M. Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal. Journal of Biological Chemistry 2004, 279:41882-41891.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 41882-41891
    • Karlsson, M.1    Mathers, J.2    Dickinson, R.J.3    Mandl, M.4    Keyse, S.M.5
  • 38
    • 13444271627 scopus 로고    scopus 로고
    • Gender differences in incidence and age at onset of mania and bipolar disorder over a 35-year period in Camberwell, England
    • Kennedy N., Boydell J., Kalidindi S., Fearon P., Jones P.B., van Os J., et al. Gender differences in incidence and age at onset of mania and bipolar disorder over a 35-year period in Camberwell, England. The American Journal of Psychiatry 2005, 162:257-262.
    • (2005) The American Journal of Psychiatry , vol.162 , pp. 257-262
    • Kennedy, N.1    Boydell, J.2    Kalidindi, S.3    Fearon, P.4    Jones, P.B.5    van Os, J.6
  • 39
    • 27544472675 scopus 로고    scopus 로고
    • Use of autosomal loci for clustering individuals and populations of East Asian origin
    • Kim J.J., Verdu P., Pakstis A.J., Speed W.C., Kidd J.R., Kidd K.K. Use of autosomal loci for clustering individuals and populations of East Asian origin. Human Genetics 2005, 117:511-519.
    • (2005) Human Genetics , vol.117 , pp. 511-519
    • Kim, J.J.1    Verdu, P.2    Pakstis, A.J.3    Speed, W.C.4    Kidd, J.R.5    Kidd, K.K.6
  • 40
    • 44349083035 scopus 로고    scopus 로고
    • Haloperidol regulates the phosphorylation level of the MEK-ERK-p90RSK signal pathway via protein phosphatase 2A in the rat frontal cortex
    • Kim S.H., Seo M.S., Jeon W.J., Yu H.S., Park H.G., Jung G.A., et al. Haloperidol regulates the phosphorylation level of the MEK-ERK-p90RSK signal pathway via protein phosphatase 2A in the rat frontal cortex. The International Journal of Neuropsychopharmacology 2008, 11:509-517.
    • (2008) The International Journal of Neuropsychopharmacology , vol.11 , pp. 509-517
    • Kim, S.H.1    Seo, M.S.2    Jeon, W.J.3    Yu, H.S.4    Park, H.G.5    Jung, G.A.6
  • 41
    • 51349128054 scopus 로고    scopus 로고
    • Dose-dependent effect of intracerebroventricular injection of ouabain on the phosphorylation of the MEK1/2-ERK1/2-p90RSK pathway in the rat brain related to locomotor activity
    • Kim S.H., Yu H.S., Park H.G., Jeon W.J., Song J.Y., Kang U.G., et al. Dose-dependent effect of intracerebroventricular injection of ouabain on the phosphorylation of the MEK1/2-ERK1/2-p90RSK pathway in the rat brain related to locomotor activity. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2008, 32:1637-1642.
    • (2008) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.32 , pp. 1637-1642
    • Kim, S.H.1    Yu, H.S.2    Park, H.G.3    Jeon, W.J.4    Song, J.Y.5    Kang, U.G.6
  • 42
    • 0035996999 scopus 로고    scopus 로고
    • Cloning and expression of the mouse dual-specificity mitogen-activated protein (MAP) kinase phosphatase Mkp3 during mouse embryogenesis
    • Klock A., Herrmann B.G. Cloning and expression of the mouse dual-specificity mitogen-activated protein (MAP) kinase phosphatase Mkp3 during mouse embryogenesis. Mechanisms of Development 2002, 116:243-247.
    • (2002) Mechanisms of Development , vol.116 , pp. 243-247
    • Klock, A.1    Herrmann, B.G.2
  • 44
    • 40849116456 scopus 로고    scopus 로고
    • Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins
    • Kuratomi G., Iwamoto K., Bundo M., Kusumi I., Kato N., Iwata N., et al. Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Molecular Psychiatry 2008, 13:429-441.
    • (2008) Molecular Psychiatry , vol.13 , pp. 429-441
    • Kuratomi, G.1    Iwamoto, K.2    Bundo, M.3    Kusumi, I.4    Kato, N.5    Iwata, N.6
  • 45
    • 33646343004 scopus 로고    scopus 로고
    • The association of DUSP6 gene with schizophrenia and bipolar disorder: its possible role in the development of bipolar disorder
    • Lee K.Y., Ahn Y.M., Joo E.J., Chang J.S., Kim Y.S. The association of DUSP6 gene with schizophrenia and bipolar disorder: its possible role in the development of bipolar disorder. Molecular Psychiatry 2006, 11:425-426.
    • (2006) Molecular Psychiatry , vol.11 , pp. 425-426
    • Lee, K.Y.1    Ahn, Y.M.2    Joo, E.J.3    Chang, J.S.4    Kim, Y.S.5
  • 46
    • 33846472047 scopus 로고    scopus 로고
    • Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development
    • Li C., Scott D.A., Hatch E., Tian X., Mansour S.L. Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development. Development 2007, 134:167-176.
    • (2007) Development , vol.134 , pp. 167-176
    • Li, C.1    Scott, D.A.2    Hatch, E.3    Tian, X.4    Mansour, S.L.5
  • 47
    • 44149117958 scopus 로고    scopus 로고
    • Association of the dusp6 (mkp3) gene with mouse brain weight and forebrain structure
    • Liu B. Association of the dusp6 (mkp3) gene with mouse brain weight and forebrain structure. Journal of Child Neurology 2008, 23:624-627.
    • (2008) Journal of Child Neurology , vol.23 , pp. 624-627
    • Liu, B.1
  • 48
    • 0036310511 scopus 로고    scopus 로고
    • BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents
    • Mai L., Jope R.S., Li X. BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents. Journal of Neurochemistry 2002, 82:75-83.
    • (2002) Journal of Neurochemistry , vol.82 , pp. 75-83
    • Mai, L.1    Jope, R.S.2    Li, X.3
  • 49
    • 57649198454 scopus 로고    scopus 로고
    • DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility
    • Maillet M., Purcell N.H., Sargent M.A., York A.J., Bueno O.F., Molkentin J.D. DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility. Journal of Biological Chemistry 2008, 283:31246-31255.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 31246-31255
    • Maillet, M.1    Purcell, N.H.2    Sargent, M.A.3    York, A.J.4    Bueno, O.F.5    Molkentin, J.D.6
  • 50
    • 34548297658 scopus 로고    scopus 로고
    • Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway
    • Matigian N., Windus L., Smith H., Filippich C., Pantelis C., McGrath J., et al. Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway. Molecular Psychiatry 2007, 12:815-825.
    • (2007) Molecular Psychiatry , vol.12 , pp. 815-825
    • Matigian, N.1    Windus, L.2    Smith, H.3    Filippich, C.4    Pantelis, C.5    McGrath, J.6
  • 54
    • 0033569786 scopus 로고    scopus 로고
    • Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in Quebec points to a locus of major effect on chromosome 12q23-q24
    • Morissette J., Villeneuve A., Bordeleau L., Rochette D., Laberge C., Gagne B., et al. Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in Quebec points to a locus of major effect on chromosome 12q23-q24. American Journal of Medical Genetics 1999, 88:567-587.
    • (1999) American Journal of Medical Genetics , vol.88 , pp. 567-587
    • Morissette, J.1    Villeneuve, A.2    Bordeleau, L.3    Rochette, D.4    Laberge, C.5    Gagne, B.6
  • 55
    • 57849159039 scopus 로고    scopus 로고
    • Functional analysis of a potassium-chloride co-transporter 3 (SLC12A6) promoter polymorphism leading to an additional DNA methylation site
    • Moser D., Ekawardhani S., Kumsta R., Palmason H., Bock C., Athanassiadou Z., et al. Functional analysis of a potassium-chloride co-transporter 3 (SLC12A6) promoter polymorphism leading to an additional DNA methylation site. Neuropsychopharmacology 2009, 34:458-467.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 458-467
    • Moser, D.1    Ekawardhani, S.2    Kumsta, R.3    Palmason, H.4    Bock, C.5    Athanassiadou, Z.6
  • 56
    • 0029910140 scopus 로고    scopus 로고
    • The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases
    • Muda M., Theodosiou A., Rodrigues N., Boschert U., Camps M., Gillieron C., et al. The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases. Journal of Biological Chemistry 1996, 271:27205-27208.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 27205-27208
    • Muda, M.1    Theodosiou, A.2    Rodrigues, N.3    Boschert, U.4    Camps, M.5    Gillieron, C.6
  • 57
    • 77956178815 scopus 로고    scopus 로고
    • Wnt2 expression and signaling is increased by different classes of antidepressant treatments
    • Okamoto H., Voleti B., Banasr M., Sarhan M., Duric V., Girgenti M.J., et al. Wnt2 expression and signaling is increased by different classes of antidepressant treatments. Biological Psychiatry 2010, 68:521-527.
    • (2010) Biological Psychiatry , vol.68 , pp. 521-527
    • Okamoto, H.1    Voleti, B.2    Banasr, M.3    Sarhan, M.4    Duric, V.5    Girgenti, M.J.6
  • 58
    • 34248595035 scopus 로고    scopus 로고
    • Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
    • Owens D.M., Keyse S.M. Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases. Oncogene 2007, 26:3203-3213.
    • (2007) Oncogene , vol.26 , pp. 3203-3213
    • Owens, D.M.1    Keyse, S.M.2
  • 60
    • 0038155088 scopus 로고    scopus 로고
    • Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum
    • Pozzi L., Hakansson K., Usiello A., Borgkvist A., Lindskog M., Greengard P., et al. Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum. Journal of Neurochemistry 2003, 86:451-459.
    • (2003) Journal of Neurochemistry , vol.86 , pp. 451-459
    • Pozzi, L.1    Hakansson, K.2    Usiello, A.3    Borgkvist, A.4    Lindskog, M.5    Greengard, P.6
  • 61
    • 12944257360 scopus 로고    scopus 로고
    • Association between bipolar disorder and monoamine oxidase A gene polymorphisms: results of a multicenter study
    • Preisig M., Bellivier F., Fenton B.T., Baud P., Berney A., Courtet P., et al. Association between bipolar disorder and monoamine oxidase A gene polymorphisms: results of a multicenter study. The American Journal of Psychiatry 2000, 157:948-955.
    • (2000) The American Journal of Psychiatry , vol.157 , pp. 948-955
    • Preisig, M.1    Bellivier, F.2    Fenton, B.T.3    Baud, P.4    Berney, A.5    Courtet, P.6
  • 62
    • 0036911138 scopus 로고    scopus 로고
    • Hydrogen peroxide as second messenger in lymphocyte activation
    • Reth M. Hydrogen peroxide as second messenger in lymphocyte activation. Nature Immunology 2002, 3:1129-1134.
    • (2002) Nature Immunology , vol.3 , pp. 1129-1134
    • Reth, M.1
  • 66
    • 0025338726 scopus 로고
    • Sex differences in the age of onset of bipolar affective illness
    • Sibisi C.D. Sex differences in the age of onset of bipolar affective illness. The British Journal of Psychiatry 1990, 156:842-845.
    • (1990) The British Journal of Psychiatry , vol.156 , pp. 842-845
    • Sibisi, C.D.1
  • 67
    • 0031570718 scopus 로고    scopus 로고
    • Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7)
    • Smith A., Price C., Cullen M., Muda M., King A., Ozanne B., et al. Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7). Genomics 1997, 42:524-527.
    • (1997) Genomics , vol.42 , pp. 524-527
    • Smith, A.1    Price, C.2    Cullen, M.3    Muda, M.4    King, A.5    Ozanne, B.6
  • 68
    • 17244381393 scopus 로고    scopus 로고
    • Feedback interactions between MKP3 and ERK MAP kinase control scleraxis expression and the specification of rib progenitors in the developing chick somite
    • Smith T.G., Sweetman D., Patterson M., Keyse S.M., Munsterberg A. Feedback interactions between MKP3 and ERK MAP kinase control scleraxis expression and the specification of rib progenitors in the developing chick somite. Development 2005, 132:1305-1314.
    • (2005) Development , vol.132 , pp. 1305-1314
    • Smith, T.G.1    Sweetman, D.2    Patterson, M.3    Keyse, S.M.4    Munsterberg, A.5
  • 69
    • 58649094194 scopus 로고    scopus 로고
    • Combining gene expression, demographic and clinical data in modeling disease: a case study of bipolar disorder and schizophrenia
    • Struyf J., Dobrin S., Page D. Combining gene expression, demographic and clinical data in modeling disease: a case study of bipolar disorder and schizophrenia. BMC Genomics 2008, 9:531.
    • (2008) BMC Genomics , vol.9 , pp. 531
    • Struyf, J.1    Dobrin, S.2    Page, D.3
  • 70
    • 25844452005 scopus 로고    scopus 로고
    • Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon
    • Suppes T., Mintz J., McElroy S.L., Altshuler L.L., Kupka R.W., Frye M.A., et al. Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon. Archives of General Psychiatry 2005, 62:1089-1096.
    • (2005) Archives of General Psychiatry , vol.62 , pp. 1089-1096
    • Suppes, T.1    Mintz, J.2    McElroy, S.L.3    Altshuler, L.L.4    Kupka, R.W.5    Frye, M.A.6
  • 71
    • 71249120180 scopus 로고    scopus 로고
    • The effect of minor allele frequency on the likelihood of obtaining false positives
    • Tabangin M.E., Woo J.G., Martin L.J. The effect of minor allele frequency on the likelihood of obtaining false positives. BMC Proceedings 2009, 3(Suppl 7):S41.
    • (2009) BMC Proceedings , vol.3 , Issue.SUPPL. 7
    • Tabangin, M.E.1    Woo, J.G.2    Martin, L.J.3
  • 72
    • 34249338745 scopus 로고    scopus 로고
    • Epigenetic aberration of the human REELIN gene in psychiatric disorders
    • Tamura Y., Kunugi H., Ohashi J., Hohjoh H. Epigenetic aberration of the human REELIN gene in psychiatric disorders. Molecular Psychiatry 2007, 12(519):93-600.
    • (2007) Molecular Psychiatry , vol.12 , Issue.519 , pp. 93-600
    • Tamura, Y.1    Kunugi, H.2    Ohashi, J.3    Hohjoh, H.4
  • 74
    • 21844435448 scopus 로고    scopus 로고
    • Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population
    • Thomson P.A., Wray N.R., Millar J.K., Evans K.L., Hellard S.L., Condie A., et al. Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Molecular Psychiatry 2005, 10:657-668. 16.
    • (2005) Molecular Psychiatry , vol.10 , Issue.16 , pp. 657-668
    • Thomson, P.A.1    Wray, N.R.2    Millar, J.K.3    Evans, K.L.4    Hellard, S.L.5    Condie, A.6
  • 75
    • 20844451579 scopus 로고    scopus 로고
    • Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor
    • Thomson P.A., Wray N.R., Thomson A.M., Dunbar D.R., Grassie M.A., Condie A., et al. Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor. Molecular Psychiatry 2005, 10:470-478.
    • (2005) Molecular Psychiatry , vol.10 , pp. 470-478
    • Thomson, P.A.1    Wray, N.R.2    Thomson, A.M.3    Dunbar, D.R.4    Grassie, M.A.5    Condie, A.6
  • 77
    • 85006245500 scopus 로고    scopus 로고
    • Association study on the DUSP6 gene, an affective disorder candidate gene on 12q23, performed by using fluorescence resonance energy transfer-based melting curve analysis on the LightCycler
    • Toyota T., Watanabe A., Shibuya H., Nankai M., Hattori E., Yamada K., et al. Association study on the DUSP6 gene, an affective disorder candidate gene on 12q23, performed by using fluorescence resonance energy transfer-based melting curve analysis on the LightCycler. Molecular Psychiatry 2000, 5:489-494.
    • (2000) Molecular Psychiatry , vol.5 , pp. 489-494
    • Toyota, T.1    Watanabe, A.2    Shibuya, H.3    Nankai, M.4    Hattori, E.5    Yamada, K.6
  • 78
    • 17444379438 scopus 로고    scopus 로고
    • Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice
    • Tremolizzo L., Doueiri M.S., Dong E., Grayson D.R., Davis J., Pinna G., et al. Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biological Psychiatry 2005, 57:500-509.
    • (2005) Biological Psychiatry , vol.57 , pp. 500-509
    • Tremolizzo, L.1    Doueiri, M.S.2    Dong, E.3    Grayson, D.R.4    Davis, J.5    Pinna, G.6
  • 80
  • 81
    • 1842784821 scopus 로고    scopus 로고
    • Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain
    • Valjent E., Pages C., Herve D., Girault J.A., Caboche J. Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain. European Journal of Neuroscience 2004, 19:1826-1836.
    • (2004) European Journal of Neuroscience , vol.19 , pp. 1826-1836
    • Valjent, E.1    Pages, C.2    Herve, D.3    Girault, J.A.4    Caboche, J.5
  • 82
    • 0034889428 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabinol-induced MAPK/ERK and Elk-1 activation in vivo depends on dopaminergic transmission
    • Valjent E., Pages C., Rogard M., Besson M.J., Maldonado R., Caboche J. Delta 9-tetrahydrocannabinol-induced MAPK/ERK and Elk-1 activation in vivo depends on dopaminergic transmission. European Journal of Neuroscience 2001, 14:342-352.
    • (2001) European Journal of Neuroscience , vol.14 , pp. 342-352
    • Valjent, E.1    Pages, C.2    Rogard, M.3    Besson, M.J.4    Maldonado, R.5    Caboche, J.6
  • 84
    • 39449117350 scopus 로고    scopus 로고
    • Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation
    • Wexler E.M., Geschwind D.H., Palmer T.D. Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation. Molecular Psychiatry 2008, 13:285-292.
    • (2008) Molecular Psychiatry , vol.13 , pp. 285-292
    • Wexler, E.M.1    Geschwind, D.H.2    Palmer, T.D.3
  • 85
    • 60849135739 scopus 로고    scopus 로고
    • A QTL on 12q influencing an inflammation marker and obesity in white women: the NHLBI Family Heart Study
    • Wu J., Pankow J.S., Tracy R.P., North K.E., Myers R.H., Feitosa M.E., et al. A QTL on 12q influencing an inflammation marker and obesity in white women: the NHLBI Family Heart Study. Obesity (Silver Spring) 2009, 17:525-531.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 525-531
    • Wu, J.1    Pankow, J.S.2    Tracy, R.P.3    North, K.E.4    Myers, R.H.5    Feitosa, M.E.6
  • 87
    • 77952287347 scopus 로고    scopus 로고
    • Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia
    • Yuan P., Zhou R., Wang Y., Li X., Li J., Chen G., et al. Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia. Journal of Affective Disorders 2010, 124:164-169.
    • (2010) Journal of Affective Disorders , vol.124 , pp. 164-169
    • Yuan, P.1    Zhou, R.2    Wang, Y.3    Li, X.4    Li, J.5    Chen, G.6
  • 88
    • 0035943699 scopus 로고    scopus 로고
    • The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
    • Yuan P.X., Huang L.D., Jiang Y.M., Gutkind J.S., Manji H.K., Chen G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. Journal of Biological Chemistry 2001, 276:31674-31683.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 31674-31683
    • Yuan, P.X.1    Huang, L.D.2    Jiang, Y.M.3    Gutkind, J.S.4    Manji, H.K.5    Chen, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.