Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos

Journal of Anatomy

Volumn 205, Issue 1, 2004, Pages 1-13

  Eblaghie, Maxwell C ^a,d   Song, Soo Jin ^b   Kim, Jae Young ^b   Akita, Keiichi ^c   Tickle, Cheryll ^a   Jung, Han Sung ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b Yonsei University   (South Korea)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Embryonic mammary gland; Fgfs; T box; Wnt

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR 9; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; WNT PROTEIN; 3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID; DNA BINDING PROTEIN; DUAL SPECIFICITY PROTEIN PHOSPHATASE 6; FGF17 PROTEIN, HUMAN; FGF17 PROTEIN, MOUSE; FGF4 PROTEIN, MOUSE; FGF8 PROTEIN, MOUSE; FGF9 PROTEIN, MOUSE; FGFR1 PROTEIN, MOUSE; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; LEF1 PROTEIN, MOUSE; LYMPHOID ENHANCER FACTOR 1; ONCOPROTEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PYRROLE DERIVATIVE; TBX3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST DEVELOPMENT; BREAST EPITHELIUM; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC CODE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IN SITU HYBRIDIZATION; METHODOLOGY; MOUSE STRAIN; ORGAN CULTURE TECHNIQUE; PRENATAL DEVELOPMENT; UDDER;

ANIMALS; DNA-BINDING PROTEINS; FEMALE; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; LYMPHOID ENHANCER-BINDING FACTOR 1; MALE; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED STRAINS; ORGAN CULTURE TECHNIQUES; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; PYRROLES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 4243141885     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0021-8782.2004.00309.x     Document Type: Article

References (49)

1. Bamshad M, Lin RC, Law DJ, Watkins WC, Krakowiak PA, Moore ME, et al. (1997) Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Nat. Genet. 16, 311-315.
2. Bocchinfuso WP, Lindzey JK, Hewitt SC, Clark JA, Myers PH, Cooper R, et al. (2000) Induction of mammary gland development in estrogen receptor-alpha knockout mice. Endocrinology 141, 2982-2994.
3. Bradbury JM, Edwards PA, Niemeyer CC, Dale TC (1995) Wnt-4 expression induces a pregnancy-like growth pattern in reconstituted mammary glands in virgin mice. Dev. Biol. 170, 553-563.
4. Casey ES, O'Reilly MA, Conlon FL, Smith JC (1998) The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element. Development 125, 3887-3894.
5. Cebra-Thomas JA, Bromer J, Gardner R, Lam GK, Sheipe H, Gilbert SF (2003) T-box gene products are required for mesenchymal induction of epithelial branching in the embryonic mouse lung. Dev. Dyn. 226, 82-90.
6. Chapman DL, Garvey N, Hancock S, Alexiou M, Agulnik SI, Gibson-Brown JJ,et al. (1996) Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev. Dyn. 206, 379-390.
7. Christiansen JH, Dennis CL, Wicking CA, Monkley SJ, Wilkinson DG, Wainwright BJ (1995) Murine Wnt-11 and Wnt-12 have temporally and spatially restricted expression patterns during embryonic development. Mech. Dev. 51, 342-350.
8. Cohn MJ, Izpisua-Belmonte JC, Abud H, Heath JK, Tickle C (1995) Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.
9. Crossley PH, Martinez S, Ohkubo Y, Rubenstein JL (2001) Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles. Neuroscience 108, 183-206.
10. DasGupta R, Fuchs E (1999) Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 126, 4557-4568.
11. Davenport TG, Jerome-Majewska LA, Papaioannou VE (2003) Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome. Development 130, 2263-2273.
12. Dickinson RJ, Eblaghie MC, Keyse SM, Morriss-Kay GM (2002) Expression of the ERK-specific MAP kinase phosphatase PYST1/MKP3 in mouse embryos during morphogenesis and early organogenesis. Mech. Dev. 113, 193-196.
13. Eblaghie MC, Lunn JS, Dickinson RJ, Munsterberg AE, Sanz-Ezquerro JJ, Farrell ER, et al. (2003) Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos. Current Biol. 17, 1009-1018.
14. Gavin BJ, McMahon AP (1992) Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Mol. Cell Biol. 12, 2418-2423.
15. van Genderen C, Okamura RM, Farinas I, Quo RGP, Arslow TG, Bruhn L, et al. (1994) Development of several organs that require inductive epithelial-mesenchymal interations is impaired in LEF-1-deficient mice. Genes Dev. 15, 2691-2703.
16. Hennighausen L, Robinson GW (2001) Signaling pathways in mammary gland development. Dev. Cell 1, 467-475.
17. Isaacs HV, Pownall ME, Slack JM (1994) eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 3, 4469-4481.
18. Jung HS, Francis-West PH, Widelitz RB, Jiang TX, Ting-Berreth S, Tickle C, et al. (1998) Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning. Dev. Biol. 196, 11-23.
19. Kawakami Y, Capdevila J, Buscher D, Itoh T, Rodriguez Esteban C, Izpisua Belmonte JC (2001) WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo. Cell 23, 891-900.
20. Kawashima T, Tomioka H, Yoshida S (1988) Inhibition of chemical mediator release from human leukocytes and lung fragments by TBX. Arerugi 37, 438-447.
21. Kengaku M, Capdevila J, Rodriguez-Esteban C, De La Pena J, Johnson RL, Belmonte JC, et al. (1998) Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. Science 280, 1274-1277.
22. Kratochwil K, Galceran J, Tontsch S, Roth W, Grosschedl R (2002) FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1 (-/-) mice. Genes Dev. 15, 3173-3185.
23. Lewis MT, Ross S, Strickland PA, Sugnet CW, Jimenez E, Hui C, et al. (2001) The Gli2 transcription factor is required for normal mouse mammary gland development. Dev. Biol. 238, 133-144.
24. Lewis MT, Ross S, Strickland PA, Sugnet CW, Jimenez E, Scott MP, et al. (1999) Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1. Development 126, 5181-5193.
25. Mailleux AA, Spencer-Dene B, Dillon C, Ndiaye D, SavonaBaron C, Itoh N, et al. (2002) Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo. Development 129, 53-60.
26. Medina D, Ullrich R, Meyn R, Wiseman R, Donehower L (2002) Environmental carcinogens and p53 tumor-suppressor gene interactions in a transgenic mouse model for mammary carcinogenesis. Environ. Mol. Mutagen. 39, 178-183.
27. Mohammadi M, McMahon G, Sun L, Tang C, Hirth P, Yeh BK, et al. (1997) Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276, 955-960.
28. Nieto MA, Patel K, Wilkinson DG (1996) In situ hybridization analysis of chick embryos in whole mount and tissue sections. Methods Cell Biol. 51, 219-235.
29. Ohuchi H, Nakagawa T, Yamauchi M, Ohata T, Yoshioka H, Kuwana T, et al. (1995) An additional limb can be induced from the flank of the chick embryo by FGF4. Biochem. Biophys. Res. Commun. 209, 809-816.
30. Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, et al. (1996) Receptor specificity of the fibroblast growth factor family. J. Biol. Chem. 21, 15292-15297.
31. Phippard DJ, Weber-Hall SJ, Sharpe PT, Naylor MS, Jayatalake H, Maas R, et al. (1996) Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development. Development 122, 2729-2737.
32. Pispa J, Mikkola ML, Mustonen T, Thesleff I (2003) Ectodysplasin, Edar and TNFRSF19 are expressed in complementary and overlapping patterns during mouse embryogenesis. Gene Expr. Patterns 3, 675-679.
33. Propper AY (1978) Wandering epithelial cells in the rabbit embryos milk line. Dev. Biol. 67, 225-231.
34. Rallis C, Bruneau BG, Del Buono J, Seidman CE, Seidman JG, Nissim S, et al. (2003) Tbx5 is required for forelimb bud formation and continued outgrowth. Development 130, 2741-2751.
35. Sakiyama JI, Yamagishi A, Kuroiwa A (2003) Tbx4-Fgf10 system controls lung bud formation during chicken embryonic development. Development 130, 1225-1234.
36. Satokata I, Ma L, Ohshima H, Bei M, Woo I, Nishizawa K, et al. (2002) Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat. Genet. 24, 391-395.
37. Schulte-Merker S, Smith JC (1995) Mesoderm formation in response to Brachyury requires FGF signalling. Curr. Biol. 5, 62-67.
38. Spencer-Dene B, Dillon C, Fantl V, Kerr K, Petiot A, Dickson C (2001) Fibroblast growth factor signalling in mouse mammary gland development. Endocr. Relat. Cancer. 8, 211-217.
39. Stern K (1993) Court-ordered caesarian sections: in whose interests? Mod. Law. Rev. 56, 238-243.
40. Takeuchi JK, Koshiba-Takeuchi K, Suzuki T, Kamimura M, Ogura K, Ogura T (2003) Tbx5 and Tbx4 trigger limb initiation through activation of the Wnt/Fgf signaling cascade. Development 130, 2729-2739.
41. Tanaka M, Cohn MJ, Ashby P, Davey M, Martin P, Tickle C (2000) Distribution of polarizing activity and potential for limb formation in mouse and chick embryos and possible relationships to polydactyly. Development 127, 4011-4021.
42. Tumpel S, Sanz-Ezquerro JJ, Isaac A, Eblaghie MC, Dobson J, Tickle C (2002) Regulation of Tbx3 expression by anteroposterior signalling in vertebrate limb development. Dev. Biol. 15, 251-262.
43. Turner CW, Gomez ET (1933) The normal development of the mammary gland of the male and female albino mouse. I. Intrauterine. Mo. Agric. Exp. Stn. Res. Bull. 182, 3-20.
44. Veltmaat JM, Mailleux AA, Thiery JP, Bellusci S (2003) Mouse embryonic mammogenesis as a model for the molecular regulation of pattern formation. Differentiation 71, 117.
45. Vogel A, Rodriguez C, Izpisua-Belmonte JC (1996) Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Develoment 122, 1737-1750.
46. Weber-Hall SJ, Phippard DJ, Niemeyer CC, Dale TC (1994) Developmental and hormonal regulation of Wnt gene expression in the mouse mammary gland. Differentiation 57, 205-214.
47. Wilkinson DG, Nieto MA (1993) Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol. 225, 361-373.
48. Wong GT, Gavin BJ, McMahon AP (1994) Differential transformation of mammary epithelial cells by Wnt genes. Mol. Cell. Biol. 14, 6278-6286.
49. Wysolmerski JJ, Philbrick WM, Dunbar ME, Lanske B, Kronenberg H, Broadus AE (1998) Rescue of the parathyroid hormonerelated protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development 125, 1285-1294.