메뉴 건너뛰기




Volumn 356, Issue , 2012, Pages 91-116

Genetic and epigenetic regulation of tcrb gene assembly

Author keywords

Chromatin; T cell receptor genes; Thymocytes; Transcription; V(D)J recombination

Indexed keywords

COHESIN; RAG1 PROTEIN; RAG2 PROTEIN; TRANSCRIPTION FACTOR CTCF;

EID: 84857728391     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/82_2011_138     Document Type: Article
Times cited : (6)

References (103)
  • 1
    • 33748850103 scopus 로고    scopus 로고
    • Regulation of T cell receptor-alpha gene recombination by transcription
    • Abarrategui I, Krangel MS (2006) Regulation of T cell receptor-alpha gene recombination by transcription. Nat Immunol 7:1109-1115
    • (2006) Nat Immunol , vol.7 , pp. 1109-1115
    • Abarrategui, I.1    Krangel, M.S.2
  • 2
    • 70349570163 scopus 로고    scopus 로고
    • Germline transcription: A key regulator of accessibility and recombination
    • Abarrategui I, Krangel MS (2009) Germline transcription: a key regulator of accessibility and recombination. Adv Exp Med Biol 650:93-102
    • (2009) Adv Exp Med Biol , vol.650 , pp. 93-102
    • Abarrategui, I.1    Krangel, M.S.2
  • 3
    • 37049009268 scopus 로고    scopus 로고
    • Regulation of T Cell Receptor β Gene Rearrangements and Allelic Exclusion by the Helix-Loop-Helix Protein, E47
    • DOI 10.1016/j.immuni.2007.11.015, PII S107476130700550X
    • Agata Y, Tamaki N, Sakamoto S, Ikawa T, Masuda K, Kawamoto H, Murre C (2007) Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47. Immunity 27:871-884 (Pubitemid 350251223)
    • (2007) Immunity , vol.27 , Issue.6 , pp. 871-884
    • Agata, Y.1    Tamaki, N.2    Sakamoto, S.3    Ikawa, T.4    Masuda, K.5    Kawamoto, H.6    Murre, C.7
  • 4
    • 0032213687 scopus 로고    scopus 로고
    • On the role of the pre-T cell receptor in αβ versus γδ T lineage commitment
    • Aifantis I, Azogui O, Feinberg J, Saint-Ruf C, Buer J, von Boehmer H (1998) On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment. Immunity 9:649-655 (Pubitemid 28557593)
    • (1998) Immunity , vol.9 , Issue.5 , pp. 649-655
    • Aifantis, I.1    Azogui, O.2    Feinberg, J.3    Saint-Ruf, C.4    Buer, J.5    Von Boehmer, H.6
  • 6
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
    • DOI 10.1016/S0092-8674(00)81967-4
    • Bell AC, West AG, Felsenfeld G (1999) The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98:387-396 (Pubitemid 29380573)
    • (1999) Cell , vol.98 , Issue.3 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 8
    • 70349563916 scopus 로고    scopus 로고
    • Molecular genetics at the T cell receptor beta locus: Insights into the regulation of V(D) J recombination
    • Bonnet M, Ferrier P, Spicuglia S (2009) Molecular genetics at the T cell receptor beta locus: insights into the regulation of V(D)J recombination. Adv Exp Med Biol 650:116-132
    • (2009) Adv Exp Med Biol , vol.650 , pp. 116-132
    • Bonnet, M.1    Ferrier, P.2    Spicuglia, S.3
  • 9
    • 0029819322 scopus 로고    scopus 로고
    • Gene-targeted deletion and replacement mutations of the T-cell receptor β-chain enhancer: The role of enhancer elements in controlling V(D)J recombination accessibility
    • DOI 10.1073/pnas.93.15.7871
    • Bories JC, Demengeot J, Davidson L, Alt FW (1996) Gene-targeted deletion and replacement mutations of the T cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility. Proc Natl Acad Sci USA 93:7871-7876 (Pubitemid 26277131)
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.15 , pp. 7871-7876
    • Bories, J.-C.1    Demengeot, J.2    Davidson, L.3    Alt, F.W.4
  • 12
    • 77958118755 scopus 로고    scopus 로고
    • Antigen receptor allelic exclusion: An update and reappraisal
    • Brady BL, Steinel NC, Bassing CH (2010) Antigen receptor allelic exclusion: an update and reappraisal. J Immunol 185:3801-3808
    • (2010) J Immunol , vol.185 , pp. 3801-3808
    • Brady, B.L.1    Steinel, N.C.2    Bassing, C.H.3
  • 13
    • 0031892787 scopus 로고    scopus 로고
    • + thymocyte differentiation
    • Chattopadhyay S, Whitehurst CE, Schwenk F, Chen J (1998) Biochemical and functional analyses of chromatin changes at the TCR-beta gene locus during CD4-CD8-to CD4+ CD8+thymocyte differentiation. J Immunol 160:1256-1267 (Pubitemid 28093423)
    • (1998) Journal of Immunology , vol.160 , Issue.3 , pp. 1256-1267
    • Chattopadhyay, S.1    Whitehurst, C.E.2    Schwenk, F.3    Chen, J.4
  • 15
    • 77951163493 scopus 로고    scopus 로고
    • Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination
    • Couedel C, Roman C, Jones A, Vezzoni P, Villa A, Cortes P (2010) Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination. J Clin Invest 120:1337-1344
    • (2010) J Clin Invest , vol.120 , pp. 1337-1344
    • Couedel, C.1    Roman, C.2    Jones, A.3    Vezzoni, P.4    Villa, A.5    Cortes, P.6
  • 16
    • 0037454957 scopus 로고    scopus 로고
    • Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling
    • DOI 10.1084/jem.20020250
    • Cowell LG, Davila M, Yang K, Kepler TB, Kelsoe G (2003) Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling. J Exp Med 197:207-220 (Pubitemid 36152315)
    • (2003) Journal of Experimental Medicine , vol.197 , Issue.2 , pp. 207-220
    • Cowell, L.G.1    Davila, M.2    Yang, K.3    Kepler, T.B.4    Kelsoe, G.5
  • 17
    • 30044450912 scopus 로고    scopus 로고
    • Single-strand recombination signal sequence nicks in vivo: Evidence for a capture model of synapsis
    • DOI 10.1038/ni1270, PII N1270
    • Curry JD, Geier JK, Schlissel MS (2005) Single-strand recombination signal sequence nicks in vivo: evidence for a capture model of synapsis. Nat Immunol 6:1272-1279 (Pubitemid 43045639)
    • (2005) Nature Immunology , vol.6 , Issue.12 , pp. 1272-1279
    • Curry, J.D.1    Geier, J.K.2    Schlissel, M.S.3
  • 18
    • 59849122478 scopus 로고    scopus 로고
    • Cutting edge: Developmental stagespecific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development
    • Degner SC, Wong TP, Jankevicius G, Feeney AJ (2009) Cutting edge: developmental stagespecific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. J Immunol 182:44-48
    • (2009) J Immunol , vol.182 , pp. 44-48
    • Degner, S.C.1    Wong, T.P.2    Jankevicius, G.3    Feeney, A.J.4
  • 19
    • 78049265380 scopus 로고    scopus 로고
    • Gene regulation: The cohesin ring connects developmental highways
    • Dorsett D (2010) Gene regulation: the cohesin ring connects developmental highways. Curr Biol 20:R886-R888
    • (2010) Curr Biol , vol.20
    • Dorsett, D.1
  • 20
    • 0033135257 scopus 로고    scopus 로고
    • Promoter element for transcription of unrearranged T-cell receptor β- chain gene in pro-T cells
    • Doty RT, Xia D, Nguyen SP, Hathaway TR, Willerford DM (1999) Promoter element for transcription of unrearranged T cell receptor beta-chain gene in pro-T cells. Blood 93:3017-3025 (Pubitemid 29200794)
    • (1999) Blood , vol.93 , Issue.9 , pp. 3017-3025
    • Doty, R.T.1    Xia, D.2    Nguyen, S.P.3    Hathaway, T.R.4    Willerford, D.M.5
  • 21
    • 34548797130 scopus 로고    scopus 로고
    • The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination
    • DOI 10.1128/MCB.00835-07
    • Drejer-Teel AH, Fugmann SD, Schatz DG (2007) The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination. Mol Cell Biol 27:6288-6299 (Pubitemid 47435737)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.18 , pp. 6288-6299
    • Drejer-Teel, A.H.1    Fugmann, S.D.2    Schatz, D.G.3
  • 22
    • 0029864993 scopus 로고    scopus 로고
    • Initiation of V(D)J recombination in vitro obeying the 12/23 rule
    • DOI 10.1038/380085a0
    • Eastman QM, Leu TM, Schatz DG (1996) Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature 380:85-88 (Pubitemid 26076243)
    • (1996) Nature , vol.380 , Issue.6569 , pp. 85-88
    • Eastman, Q.M.1    Leu, T.M.J.2    Schatz, D.G.3
  • 23
    • 77951215592 scopus 로고    scopus 로고
    • The mouse immunoglobulin heavy chain V-D intergenic sequence contains insulators that may regulate ordered V(D)J recombination
    • Featherstone K, Wood AL, Bowen AJ, Corcoran AE (2010) The mouse immunoglobulin heavy chain V-D intergenic sequence contains insulators that may regulate ordered V(D)J recombination. J Biol Chem 285:9327-9338
    • (2010) J Biol Chem , vol.285 , pp. 9327-9338
    • Featherstone, K.1    Wood, A.L.2    Bowen, A.J.3    Corcoran, A.E.4
  • 24
    • 70349560864 scopus 로고    scopus 로고
    • Genetic and epigenetic control of v gene rearrangement frequency
    • Feeney AJ (2009) Genetic and epigenetic control of V gene rearrangement frequency. Adv Exp Med Biol 650:73-81
    • (2009) Adv Exp Med Biol , vol.650 , pp. 73-81
    • Feeney, A.J.1
  • 25
    • 84887212428 scopus 로고    scopus 로고
    • Initiation of V(D) J recombination by Dbeta-associated recombination signal sequences: A critical control point in TCRbeta gene assembly
    • Franchini DM, Benoukraf T, Jaeger S, Ferrier P, Payet-Bornet D (2009) Initiation of V(D)J recombination by Dbeta-associated recombination signal sequences: a critical control point in TCRbeta gene assembly. PLoS ONE 4:e4575
    • (2009) PLoS ONE , vol.4
    • Franchini, D.M.1    Benoukraf, T.2    Jaeger, S.3    Ferrier, P.4    Payet-Bornet, D.5
  • 26
    • 0033168204 scopus 로고    scopus 로고
    • Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase
    • DOI 10.1093/emboj/18.13.3712
    • Golding A, Chandler S, Ballestar E, Wolffe AP, Schlissel MS (1999) Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase. Embo J 18:3712-3723 (Pubitemid 29308850)
    • (1999) EMBO Journal , vol.18 , Issue.13 , pp. 3712-3723
    • Golding, A.1    Chandler, S.2    Ballestar, E.3    Wolffe, A.P.4    Schlissel, M.S.5
  • 27
    • 0022444852 scopus 로고
    • Rearrangement and expression of T cell antigen receptor and γ genes during thymic development
    • Haars R, Kronenberg M, Gallatin WM, Weissman IL, Owen FL, Hood L (1986) Rearrangement and expression of T cell antigen receptor and gamma genes during thymic development. J Exp Med 164:1-24 (Pubitemid 16069218)
    • (1986) Journal of Experimental Medicine , vol.164 , Issue.1 , pp. 1-24
    • Haars, R.1    Kronenberg, M.2    Gallatin, W.M.3
  • 29
    • 33846505022 scopus 로고    scopus 로고
    • Key factors in the organized chaos of early T cell development
    • DOI 10.1038/ni1436, PII NI1436
    • Hayday AC, Pennington DJ (2007) Key factors in the organized chaos of early T cell development. Nat Immunol 8:137-144 (Pubitemid 46152644)
    • (2007) Nature Immunology , vol.8 , Issue.2 , pp. 137-144
    • Hayday, A.C.1    Pennington, D.J.2
  • 30
    • 0033152430 scopus 로고    scopus 로고
    • A developmental switch from TCRδ enhancer to TCRα enhancer function during thymocyte maturation
    • DOI 10.1016/S1074-7613(00)80071-0
    • Hernandez-Munain C, Sleckman BP, Krangel MS (1999) A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation. Immunity 10:723-733 (Pubitemid 29302925)
    • (1999) Immunity , vol.10 , Issue.6 , pp. 723-733
    • Hernandez-Munain, C.1    Sleckman, B.P.2    Krangel, M.S.3
  • 31
    • 70349335528 scopus 로고    scopus 로고
    • Mechanisms of transcriptional repression by histone lysine methylation
    • Hublitz P, Albert M, Peters AH (2009) Mechanisms of transcriptional repression by histone lysine methylation. Int J Dev Biol 53:335-354
    • (2009) Int J Dev Biol , vol.53 , pp. 335-354
    • Hublitz, P.1    Albert, M.2    Peters, A.H.3
  • 32
    • 13444268486 scopus 로고    scopus 로고
    • Regulation of T cell receptor β allelic exclusion at a level beyond accessibility
    • DOI 10.1038/ni1157
    • Jackson A, Kondilis HD, Khor B, Sleckman BP, Krangel MS (2005) Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility. Nat Immunol 6:189-197 (Pubitemid 40268200)
    • (2005) Nature Immunology , vol.6 , Issue.2 , pp. 189-197
    • Jackson, A.1    Kondilis, H.D.2    Khor, B.3    Sleckman, B.P.4    Krangel, M.S.5
  • 33
    • 26844507374 scopus 로고    scopus 로고
    • Allele-specific regulation of TCRβ variable gene segment chromatin structure
    • Jackson AM, Krangel MS (2005) Allele-specific regulation of TCR beta variable gene segment chromatin structure. J Immunol 175:5186-5191 (Pubitemid 41456403)
    • (2005) Journal of Immunology , vol.175 , Issue.8 , pp. 5186-5191
    • Jackson, A.M.1    Krangel, M.S.2
  • 34
    • 34547115451 scopus 로고    scopus 로고
    • Antigen receptor diversification and chromosome translocations
    • DOI 10.1038/ni1498, PII NI1498
    • Jankovic M, Nussenzweig A, Nussenzweig MC (2007) Antigen receptor diversification and chromosome translocations. Nat Immunol 8:801-808 (Pubitemid 47099032)
    • (2007) Nature Immunology , vol.8 , Issue.8 , pp. 801-808
    • Jankovic, M.1    Nussenzweig, A.2    Nussenzweig, M.C.3
  • 35
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • DOI 10.1126/science.1063127
    • Jenuwein T, Allis CD (2001) Translating the histone code. Science 293:1074-1080 (Pubitemid 32758077)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 36
    • 41949121201 scopus 로고    scopus 로고
    • The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions
    • DOI 10.1016/j.cell.2008.03.024, PII S0092867408004406
    • Jhunjhunwala S, van Zelm MC, Peak MM, Cutchin S, Riblet R, van Dongen JJ, Grosveld FG, Knoch TA, Murre C (2008) The 3D-structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions. Cell 133:265-279 (Pubitemid 351512300)
    • (2008) Cell , vol.133 , Issue.2 , pp. 265-279
    • Jhunjhunwala, S.1    Van Zelm, M.C.2    Peak, M.M.3    Cutchin, S.4    Riblet, R.5    Van Dongen, J.J.M.6    Grosveld, F.G.7    Knoch, T.A.8    Murre, C.9
  • 37
    • 68049086918 scopus 로고    scopus 로고
    • Chromatin architecture and the generation of antigen receptor diversity
    • Jhunjhunwala S, van Zelm MC, Peak MM, Murre C (2009) Chromatin architecture and the generation of antigen receptor diversity. Cell 138:435-448
    • (2009) Cell , vol.138 , pp. 435-448
    • Jhunjhunwala, S.1    Van Zelm, M.C.2    Peak, M.M.3    Murre, C.4
  • 39
    • 77951893700 scopus 로고    scopus 로고
    • The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci
    • Ji Y, Resch W, Corbett E, Yamane A, Casellas R, Schatz DG (2010b) The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci. Cell 141:419-431
    • (2010) Cell , vol.141 , pp. 419-431
    • Ji, Y.1    Resch, W.2    Corbett, E.3    Yamane, A.4    Casellas, R.5    Schatz, D.G.6
  • 40
    • 34247630198 scopus 로고    scopus 로고
    • Germline transcription from T-cell receptor Vβ gene is uncoupled from allelic exclusion
    • DOI 10.1038/sj.emboj.7601671, PII 7601671
    • Jia J, Kondo M, Zhuang Y (2007) Germline transcription from T cell receptor Vbeta gene is uncoupled from allelic exclusion. EMBO J 26:2387-2399 (Pubitemid 46685854)
    • (2007) EMBO Journal , vol.26 , Issue.9 , pp. 2387-2399
    • Jia, J.1    Kondo, M.2    Zhuang, Y.3
  • 41
    • 0036682598 scopus 로고    scopus 로고
    • Ordered assembly of the V(D)J synaptic complex ensures accurate recombination
    • DOI 10.1093/emboj/cdf394
    • Jones JM, Gellert M (2002) Ordered assembly of the V(D)J synaptic complex ensures accurate recombination. Embo J 21:4162-4171 (Pubitemid 34857448)
    • (2002) EMBO Journal , vol.21 , Issue.15 , pp. 4162-4171
    • Jones, J.M.1    Gellert, M.2
  • 42
    • 0037242580 scopus 로고    scopus 로고
    • Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted V(D)J recombination in nonlymphoid cells
    • DOI 10.1016/S1074-7613(02)00507-1
    • Jung D, Bassing CH, Fugmann SD, Cheng HL, Schatz DG, Alt FW (2003) Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. Immunity 18:65-74 (Pubitemid 36120688)
    • (2003) Immunity , vol.18 , Issue.1 , pp. 65-74
    • Jung, D.1    Bassing, C.H.2    Fugmann, S.D.3    Cheng, H.-L.4    Schatz, D.G.5    Alt, F.W.6
  • 44
    • 0842324785 scopus 로고    scopus 로고
    • The nucleosome: From genomic organization to genomic regulation
    • DOI 10.1016/S0092-8674(04)00044-3
    • Khorasanizadeh S (2004) The nucleosome: from genomic organization to genomic regulation. Cell 116:259-272 (Pubitemid 38167316)
    • (2004) Cell , vol.116 , Issue.2 , pp. 259-272
    • Khorasanizadeh, S.1
  • 46
    • 65249145203 scopus 로고    scopus 로고
    • Mechanics of T cell receptor gene rearrangement
    • Krangel MS (2009) Mechanics of T cell receptor gene rearrangement. Curr Opin Immunol 21:133-139
    • (2009) Curr Opin Immunol , vol.21 , pp. 133-139
    • Krangel, M.S.1
  • 47
    • 0033638506 scopus 로고    scopus 로고
    • Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D) J cleavage of nucleosomal DNA
    • Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA (2000) Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol Cell 6:1037-1048
    • (2000) Mol Cell , vol.6 , pp. 1037-1048
    • Kwon, J.1    Morshead, K.B.2    Guyon, J.R.3    Kingston, R.E.4    Oettinger, M.A.5
  • 48
    • 77956153243 scopus 로고    scopus 로고
    • The language of histone crosstalk
    • Lee JS, Smith E, Shilatifard A (2010) The language of histone crosstalk. Cell 142:682-685
    • (2010) Cell , vol.142 , pp. 682-685
    • Lee, J.S.1    Smith, E.2    Shilatifard, A.3
  • 49
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • DOI 10.1016/j.cell.2007.01.015, PII S0092867407001092
    • Li B, Carey M, Workman JL (2007) The role of chromatin during transcription. Cell 128:707-719 (Pubitemid 46273570)
    • (2007) Cell , vol.128 , Issue.4 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 50
    • 35349024178 scopus 로고    scopus 로고
    • A Plant Homeodomain in Rag-2 that Binds Hypermethylated Lysine 4 of Histone H3 Is Necessary for Efficient Antigen-Receptor-Gene Rearrangement
    • DOI 10.1016/j.immuni.2007.09.005, PII S1074761307004487
    • Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S (2007) A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigenreceptor-gene rearrangement. Immunity 27:561-571 (Pubitemid 47615506)
    • (2007) Immunity , vol.27 , Issue.4 , pp. 561-571
    • Liu, Y.1    Subrahmanyam, R.2    Chakraborty, T.3    Sen, R.4    Desiderio, S.5
  • 51
    • 3242887613 scopus 로고    scopus 로고
    • In vitro and in vivo studies on the generation of the primary T-cell receptor repertoire
    • DOI 10.1111/j.0105-2896.2004.00170.x
    • Livak F (2004) In vitro and in vivo studies on the generation of the primary T cell receptor repertoire. Immunol Rev 200:23-35 (Pubitemid 38998190)
    • (2004) Immunological Reviews , vol.200 , pp. 23-35
    • Livak, F.1
  • 52
    • 0034605064 scopus 로고    scopus 로고
    • Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination
    • Mathieu N, Hempel WM, Spicuglia S, Verthuy C, Ferrier P (2000) Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: implications for the control of TCR-beta locus recombination. J Exp Med 192:625-636
    • (2000) J Exp Med , vol.192 , pp. 625-636
    • Mathieu, N.1    Hempel, W.M.2    Spicuglia, S.3    Verthuy, C.4    Ferrier, P.5
  • 54
    • 49149126191 scopus 로고    scopus 로고
    • Differential activation of dual promoters alters Dbeta2 germline transcription during thymocyte development
    • McMillan RE, Sikes ML (2008) Differential activation of dual promoters alters Dbeta2 germline transcription during thymocyte development. J Immunol 180:3218-3228
    • (2008) J Immunol , vol.180 , pp. 3218-3228
    • McMillan, R.E.1    Sikes, M.L.2
  • 55
    • 68749118110 scopus 로고    scopus 로고
    • Promoter activity 50 of Dbeta2 is coordinated by E47, Runx1, and GATA-3
    • McMillan RE, Sikes ML (2009) Promoter activity 50 of Dbeta2 is coordinated by E47, Runx1, and GATA-3. Mol Immunol 46:3009-3017
    • (2009) Mol Immunol , vol.46 , pp. 3009-3017
    • McMillan, R.E.1    Sikes, M.L.2
  • 56
    • 58149333734 scopus 로고    scopus 로고
    • Long-range chromosomal interactions and gene regulation
    • Miele A, Dekker J (2008) Long-range chromosomal interactions and gene regulation. Mol Biosyst 4:1046-1057
    • (2008) Mol Biosyst , vol.4 , pp. 1046-1057
    • Miele, A.1    Dekker, J.2
  • 59
    • 70350088522 scopus 로고    scopus 로고
    • Developmental trajectories in early hematopoiesis
    • Murre C (2009) Developmental trajectories in early hematopoiesis. Genes Dev 23:2366-2370
    • (2009) Genes Dev , vol.23 , pp. 2366-2370
    • Murre, C.1
  • 61
    • 0018307304 scopus 로고
    • Higher order structure of chromosomes
    • DOI 10.1007/BF00286426
    • Okada TA, Comings DE (1979) Higher order structure of chromosomes. Chromosoma 72:1-14 (Pubitemid 9249471)
    • (1979) Chromosoma , vol.72 , Issue.1 , pp. 1-14
    • Okada, T.A.1    Comings, D.E.2
  • 62
    • 34547112535 scopus 로고    scopus 로고
    • Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes
    • DOI 10.1038/ni1481, PII NI1481
    • Osipovich O, Cobb RM, Oestreich KJ, Pierce S, Ferrier P, Oltz EM (2007) Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes. Nat Immunol 8:809-816 (Pubitemid 47099033)
    • (2007) Nature Immunology , vol.8 , Issue.8 , pp. 809-816
    • Osipovich, O.1    Cobb, R.M.2    Oestreich, K.J.3    Pierce, S.4    Ferrier, P.5    Oltz, E.M.6
  • 64
    • 78249257258 scopus 로고    scopus 로고
    • Regulation of antigen receptor gene assembly by geneticepigenetic crosstalk
    • Osipovich O, Oltz EM (2010) Regulation of antigen receptor gene assembly by geneticepigenetic crosstalk. Semin Immunol 22:313-322
    • (2010) Semin Immunol , vol.22 , pp. 313-322
    • Osipovich, O.1    Oltz, E.M.2
  • 66
    • 0017652886 scopus 로고
    • The structure of histone-depleted metaphase chromosomes
    • Paulson JR, Laemmli UK (1977) The structure of histone-depleted metaphase chromosomes. Cell 12:817-828
    • (1977) Cell , vol.12 , pp. 817-828
    • Paulson, J.R.1    Laemmli, U.K.2
  • 67
    • 2942516896 scopus 로고    scopus 로고
    • Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
    • DOI 10.1016/j.immuni.2004.05.004, PII S1074761304001347
    • Porritt HE, Rumfelt LL, Tabrizifard S, Schmitt TM, Zuniga-Pflucker JC, Petrie HT (2004) Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 20:735-745 (Pubitemid 38757443)
    • (2004) Immunity , vol.20 , Issue.6 , pp. 735-745
    • Porritt, H.E.1    Rumfelt, L.L.2    Tabrizifard, S.3    Schmitt, T.M.4    Zuniga-Pflucker, J.C.5    Petrie, H.T.6
  • 69
    • 33745790132 scopus 로고    scopus 로고
    • Chromatin remodelling: The industrial revolution of DNA around histones
    • DOI 10.1038/nrm1945, PII NRM1945
    • Saha A, Wittmeyer J, Cairns BR (2006) Chromatin remodelling: the industrial revolution of DNA around histones. Nat Rev Mol Cell Biol 7:437-447 (Pubitemid 44050097)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.6 , pp. 437-447
    • Saha, A.1    Wittmeyer, J.2    Cairns, B.R.3
  • 70
    • 13244275244 scopus 로고    scopus 로고
    • Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells
    • DOI 10.1101/gad.1254305
    • Sayegh CE, Jhunjhunwala S, Riblet R, Murre C (2005) Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. Genes Dev 19:322-327 (Pubitemid 40189295)
    • (2005) Genes and Development , vol.19 , Issue.3 , pp. 322-327
    • Sayegh, C.1    Jhunjhunwala, S.2    Riblet, R.3    Murre, C.4
  • 71
    • 0024281350 scopus 로고
    • Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts
    • Schatz DG, Baltimore D (1988) Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts. Cell 53:107-115
    • (1988) Cell , vol.53 , pp. 107-115
    • Schatz, D.G.1    Baltimore, D.2
  • 73
    • 45549086756 scopus 로고    scopus 로고
    • Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments
    • DOI 10.1038/ni.1624, PII NI.1624
    • Schlimgen RJ, Reddy KL, Singh H, Krangel MS (2008) Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. Nat Immunol 9:802-809 (Pubitemid 351859164)
    • (2008) Nature Immunology , vol.9 , Issue.7 , pp. 802-809
    • Schlimgen, R.J.1    Reddy, K.L.2    Singh, H.3    Krangel, M.S.4
  • 74
    • 66749124789 scopus 로고    scopus 로고
    • H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: Implications for translocations
    • Shimazaki N, Tsai AG, Lieber MR (2009) H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations. Mol Cell 34:535-544
    • (2009) Mol Cell , vol.34 , pp. 535-544
    • Shimazaki, N.1    Tsai, A.G.2    Lieber, M.R.3
  • 75
    • 0035881859 scopus 로고    scopus 로고
    • Distinct control of the frequency and allelic exclusion of the gene V β rearrangement at the TCRβ locus
    • Sieh P, Chen J (2001) Distinct control of the frequency and allelic exclusion of the V beta gene rearrangement at the TCR beta locus. J Immunol 167:2121-2129 (Pubitemid 32747521)
    • (2001) Journal of Immunology , vol.167 , Issue.4 , pp. 2121-2129
    • Sieh, P.1    Chen, J.2
  • 77
    • 0032145405 scopus 로고    scopus 로고
    • A developmental stage-specific promoter directs germline transcription of Dβj gene segments in precursor T lymphocytes
    • Sikes ML, Gomez RJ, Song J, Oltz EM (1998) A developmental stage-specific promoter directs germline transcription of D beta J beta gene segments in precursor T lymphocytes. J Immunol 161:1399-1405 (Pubitemid 28380569)
    • (1998) Journal of Immunology , vol.161 , Issue.3 , pp. 1399-1405
    • Sikes, M.L.1    Gomez, K.J.2    Song, J.3    Oltz, E.M.4
  • 78
    • 0037125979 scopus 로고    scopus 로고
    • Regulation of V(D)J recombination: A dominant role for promoter positioning in gene segment accessibility
    • Sikes ML, Meade A, Tripathi R, Krangel MS, Oltz EM (2002) Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility. Proc Natl Acad Sci USA 99:12309-12314
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12309-12314
    • Sikes, M.L.1    Meade, A.2    Tripathi, R.3    Krangel, M.S.4    Oltz, E.M.5
  • 79
    • 0032958101 scopus 로고    scopus 로고
    • Regulation of V(D)Jrecombination by transcriptional promoters
    • Sikes ML, Suarez CC, Oltz EM (1999) Regulation of V(D)J recombination by transcriptional promoters. Mol Cell Biol 19:2773-2781
    • (1999) Mol Cell Biol , vol.19 , pp. 2773-2781
    • Sikes, M.L.1    Suarez, C.C.2    Oltz, E.M.3
  • 80
    • 34248583377 scopus 로고    scopus 로고
    • Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes
    • DOI 10.1038/ni1448, PII NI1448
    • Skok JA, Gisler R, Novatchkova M, Farmer D, de Laat W, Busslinger M (2007) Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes. Nat Immunol 8:378-387 (Pubitemid 46745413)
    • (2007) Nature Immunology , vol.8 , Issue.4 , pp. 378-387
    • Skok, J.A.1    Gisler, R.2    Novatchkova, M.3    Farmer, D.4    De Laat, W.5    Busslinger, M.6
  • 82
    • 0029894165 scopus 로고    scopus 로고
    • Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
    • DOI 10.1016/S0092-8674(00)81272-6
    • Stanhope-Baker P, Hudson KM, Shaffer AL, Constantinescu A, Schlissel MS (1996) Cell typespecific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell 85:887-897 (Pubitemid 26192139)
    • (1996) Cell , vol.85 , Issue.6 , pp. 887-897
    • Stanhope-Baker, P.1    Hudson, K.M.2    Shaffer, A.L.3    Constantinescu, A.4    Schlissel, M.S.5
  • 83
    • 0030959068 scopus 로고    scopus 로고
    • Initiation of V(D)J recombination in vivo: Role of recombination signal sequences in formation of single and paired double-strand breaks
    • DOI 10.1093/emboj/16.10.2656
    • Steen SB, Gomelsky L, Speidel SL, Roth DB (1997) Initiation of V(D)J recombination in vivo: role of recombination signal sequences in formation of single and paired double-strand breaks. Embo J 16:2656-2664 (Pubitemid 27226204)
    • (1997) EMBO Journal , vol.16 , Issue.10 , pp. 2656-2664
    • Steen, S.B.1    Gomelsky, L.2    Speidel, S.L.3    Roth, D.B.4
  • 84
    • 0032126295 scopus 로고    scopus 로고
    • V(D)J recombination signal recognition: Distinct, overlapping DNA- protein contacts in complexes containing RAG1 with and without RAG2
    • DOI 10.1016/S1074-7613(00)80593-2
    • Swanson PC, Desiderio S (1998) V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2. Immunity 9:115-125 (Pubitemid 28361300)
    • (1998) Immunity , vol.9 , Issue.1 , pp. 115-125
    • Swanson, P.C.1    Desiderio, S.2
  • 85
    • 70349572500 scopus 로고    scopus 로고
    • Early steps of V(D)J rearrangement: Insights from biochemical studies of RAG-RSS complexes
    • Swanson PC, Kumar S, Raval P (2009) Early steps of V(D)J rearrangement: insights from biochemical studies of RAG-RSS complexes. Adv Exp Med Biol 650:1-15
    • (2009) Adv Exp Med Biol , vol.650 , pp. 1-15
    • Swanson, P.C.1    Kumar, S.2    Raval, P.3
  • 86
    • 70349571325 scopus 로고    scopus 로고
    • Dynamic regulation of antigen receptor gene assembly
    • Thomas LR, Cobb RM, Oltz EM (2009) Dynamic regulation of antigen receptor gene assembly. Adv Exp Med Biol 650:103-115
    • (2009) Adv Exp Med Biol , vol.650 , pp. 103-115
    • Thomas, L.R.1    Cobb, R.M.2    Oltz, E.M.3
  • 87
    • 3242886301 scopus 로고    scopus 로고
    • Regulation of T-cell receptor β-chain gene assembly by recombination signals: The beyond 12/23 restriction
    • DOI 10.1111/j.0105-2896.2004.00156.x
    • Tillman RE, Wooley AL, Hughes MM, Khor B, Sleckman BP (2004) Regulation of T cell receptor beta-chain gene assembly by recombination signals: the beyond 12/23 restriction. Immunol Rev 200:36-43 (Pubitemid 38998191)
    • (2004) Immunological Reviews , vol.200 , pp. 36-43
    • Tillman, R.E.1    Wooley, A.L.2    Hughes, M.M.3    Khor, B.4    Sleckman, B.P.5
  • 88
    • 0036489183 scopus 로고    scopus 로고
    • A change in the structure of Vβ chromatin associated with TCR β allelic exclusion
    • Tripathi R, Jackson A, Krangel MS (2002) A change in the structure of Vb chromatin associated with TCR b allelic exclusion. Journal of Immunology 168:2316-2324 (Pubitemid 34171833)
    • (2002) Journal of Immunology , vol.168 , Issue.5 , pp. 2316-2324
    • Tripathi, R.1    Jackson, A.2    Krangel, M.S.3
  • 90
    • 0023882920 scopus 로고
    • In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes
    • DOI 10.1016/0092-8674(88)90425-4
    • Uematsu Y, Ryser S, Dembic Z, Borgulya P, Krimpenfort P, Berns A, von Boehmer H, Steinmetz M (1988) In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes. Cell 52:831-841 (Pubitemid 18095349)
    • (1988) Cell , vol.52 , Issue.6 , pp. 831-841
    • Uematsu, Y.1    Ryser, S.2    Dembic, Z.3    Borgulya, P.4    Krimpenfort, P.5    Berns, A.6    Von Boehmer, H.7    Steinmetz, M.8
  • 91
    • 0019856949 scopus 로고
    • Transcription of the unrearranged mouse C(≃) locus: Sequence of the initiation region and comparison of activity with a rearranged V(κ)-C(κ) gene
    • Van Ness BG, Weigert M, Coleclough C, Mather EL, Kelley DE, Perry RP (1981) Transcription of the unrearranged mouse C kappa locus: sequence of the initiation region and comparison of activity with a rearranged V kappa-C kappa gene. Cell 27:593-602 (Pubitemid 12200796)
    • (1981) Cell , vol.27 , Issue.II3 , pp. 593-602
    • Van Ness, B.G.1    Weigert, M.2    Coleclough, C.3
  • 92
    • 35548990188 scopus 로고    scopus 로고
    • We gather together: insulators and genome organization
    • DOI 10.1016/j.gde.2007.08.005, PII S0959437X07001566, Differentiation and Gene Regulation
    • Wallace JA, Felsenfeld G (2007) We gather together: insulators and genome organization. Curr Opin Genet Dev 17:400-407 (Pubitemid 350016897)
    • (2007) Current Opinion in Genetics and Development , vol.17 , Issue.5 , pp. 400-407
    • Wallace, J.A.1    Felsenfeld, G.2
  • 93
    • 45549101973 scopus 로고    scopus 로고
    • Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition
    • DOI 10.1038/ni.1614, PII NI.1614
    • Wang X, Xiao G, Zhang Y, Wen X, Gao X, Okada S, Liu X (2008) Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition. Nat Immunol 9:794-801 (Pubitemid 351859163)
    • (2008) Nature Immunology , vol.9 , Issue.7 , pp. 794-801
    • Wang, X.1    Xiao, G.2    Zhang, Y.3    Wen, X.4    Gao, X.5    Okada, S.6    Liu, X.7
  • 94
    • 75649147458 scopus 로고    scopus 로고
    • Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells
    • Weishaupt H, Sigvardsson M, Attema JL (2010) Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells. Blood 115:247-256
    • (2010) Blood , vol.115 , pp. 247-256
    • Weishaupt, H.1    Sigvardsson, M.2    Attema, J.L.3
  • 96
    • 0033103012 scopus 로고    scopus 로고
    • Control of V(D)J recombinational accessibility of the Dβ1 gene segment at the TCRβ locus by a germline promoter
    • Whitehurst CE, Chattopadhyay S, Chen J (1999) Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter. Immunity 10:313-322 (Pubitemid 29165286)
    • (1999) Immunity , vol.10 , Issue.3 , pp. 313-322
    • Whitehurst, C.E.1    Chattopadhyay, S.2    Chen, J.3
  • 97
    • 0037243276 scopus 로고    scopus 로고
    • Dramatically Increased Rearrangement and Peripheral Representation of Vβ14 Driven by the 3′Dβ1 Recombination Signal Sequence
    • DOI 10.1016/S1074-7613(02)00515-0
    • Wu C, Bassing CH, Jung D, Woodman BB, Foy D, Alt FW (2003) Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 30Dbeta1 recombination signal sequence. Immunity 18:75-85 (Pubitemid 36120689)
    • (2003) Immunity , vol.18 , Issue.1 , pp. 75-85
    • Wu, C.1    Bassing, C.H.2    Jung, D.3    Woodman, B.B.4    Foy, D.5    Alt, F.W.6
  • 100
    • 72849110608 scopus 로고    scopus 로고
    • Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells
    • Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST (2009) Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev 23:2824-2838
    • (2009) Genes Dev , vol.23 , pp. 2824-2838
    • Xu, J.1    Watts, J.A.2    Pope, S.D.3    Gadue, P.4    Kamps, M.5    Plath, K.6    Zaret, K.S.7    Smale, S.T.8
  • 101
    • 0021983551 scopus 로고
    • Developmentally controlled and tissue-specific expression of unrearranged V(H) gene segments
    • Yancopoulos GD, Alt FW (1985) Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell 40:271-281 (Pubitemid 15138455)
    • (1985) Cell , vol.40 , Issue.2 , pp. 271-281
    • Yancopoulos, G.D.1    Alt, F.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.