-
1
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso J.A. (2007). Models, mechanisms and clinical evidence for cancer dormancy. Nat. Rev. Cancer 7, 834-846.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
2
-
-
5444256238
-
Self-renewal and solid tumor stem cells
-
Al-Hajj M. and Clarke M.F. (2004). Self-renewal and solid tumor stem cells. Oncogene 23, 7274-7282.
-
(2004)
Oncogene
, vol.23
, pp. 7274-7282
-
-
Al-Hajj, M.1
Clarke, M.F.2
-
3
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J. and Clarke M.F. (2003). Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 100, 3983-3988.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
4
-
-
0842281433
-
Therapeutic implications of cancer stem cells
-
Al-Hajj M., Becker M.W., Wicha M., Weissman I. and Clarke M.F. (2004). Therapeutic implications of cancer stem cells. Curr. Opin. Genet. Dev. 14, 43-47.
-
(2004)
Curr. Opin. Genet. Dev
, vol.14
, pp. 43-47
-
-
Al-Hajj, M.1
Becker, M.W.2
Wicha, M.3
Weissman, I.4
Clarke, M.F.5
-
5
-
-
0036781811
-
Ligand-targeted therapeutics in anticancer therapy
-
Allen T.M. (2002). Ligand-targeted therapeutics in anticancer therapy. Nat. Rev. Cancer 2, 750-763.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 750-763
-
-
Allen, T.M.1
-
6
-
-
33746265425
-
An integrative approach for the identification of quantitative trait loci
-
SUPPL
-
Arbilly M., Pisante A., Devor M. and Darvasi A. (2006). An integrative approach for the identification of quantitative trait loci. Anim. Genet. 37 (Suppl 1), 7-9.
-
(2006)
Anim. Genet
, vol.37
, Issue.1
, pp. 7-9
-
-
Arbilly, M.1
Pisante, A.2
Devor, M.3
Darvasi, A.4
-
7
-
-
0037169357
-
Cancer as a complex genetic trait: Tumor susceptibility in humans and mouse models
-
Balmain A. (2002). Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models. Cell 108, 145-152.
-
(2002)
Cell
, vol.108
, pp. 145-152
-
-
Balmain, A.1
-
8
-
-
0034109921
-
Carcinogenesis in mouse and human cells: Parallels and paradoxes
-
Balmain A. and Harris C.C. (2000). Carcinogenesis in mouse and human cells: parallels and paradoxes. Carcinogenesis 21, 371-377.
-
(2000)
Carcinogenesis
, vol.21
, pp. 371-377
-
-
Balmain, A.1
Harris, C.C.2
-
9
-
-
0037370476
-
The genetics and genomics of cancer
-
Suppl
-
Balmain A., Gray J. and Ponder B. (2003). The genetics and genomics of cancer. Nat. Genet. 33 (Suppl), 238-244.
-
(2003)
Nat. Genet
, vol.33
, pp. 238-244
-
-
Balmain, A.1
Gray, J.2
Ponder, B.3
-
10
-
-
0038454621
-
Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment
-
Bhatia R., Holtz M., Niu N., Gray R., Snyder D.S., Sawyers C.L., Arber D.A., Slovak M.L. and Forman S.J. (2003). Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment. Blood 101, 4701-4707.
-
(2003)
Blood
, vol.101
, pp. 4701-4707
-
-
Bhatia, R.1
Holtz, M.2
Niu, N.3
Gray, R.4
Snyder, D.S.5
Sawyers, C.L.6
Arber, D.A.7
Slovak, M.L.8
Forman, S.J.9
-
11
-
-
79955980366
-
c-Raf, but not BRaf, is essential for development of K-Ras oncogene-driven nonsmall cell lung carcinoma
-
Blasco R.B., Francoz S., Santamaría D., Cañamero M., Dubus P., Charron J., Baccarini M., and Barbacid M. (2011). c-Raf, but not BRaf, is essential for development of K-Ras oncogene-driven nonsmall cell lung carcinoma. Cancer Cell 19, 652-663.
-
(2011)
Cancer Cell
, vol.19
, pp. 652-663
-
-
Blasco, R.B.1
Francoz, S.2
Santamaría, D.3
Cañamero, M.4
Dubus, P.5
Charron, J.6
Baccarini, M.7
Barbacid, M.8
-
12
-
-
0037370137
-
Pathology of mouse models of intestinal cancer: Consensus report and recommendations
-
Boivin G.P., Washington K., Yang K., Ward J.M., Pretlow T.P., Russell R., Besselsen D.G., Godfrey V.L., Doetschman T., Dove W.F., Pitot H.C., Halberg R.B., Itzkowitz S.H., Groden J. and Coffey R.J. (2003). Pathology of mouse models of intestinal cancer: consensus report and recommendations. Gastroenterology 124, 762-777.
-
(2003)
Gastroenterology
, vol.124
, pp. 762-777
-
-
Boivin, G.P.1
Washington, K.2
Yang, K.3
Ward, J.M.4
Pretlow, T.P.5
Russell, R.6
Besselsen, D.G.7
Godfrey, V.L.8
Doetschman, T.9
Dove, W.F.10
Pitot, H.C.11
Halberg, R.B.12
Itzkowitz, S.H.13
Groden, J.14
Coffey, R.J.15
-
13
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D. and Dick J.E. (1997). Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3, 730-737.
-
(1997)
Nat. Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
14
-
-
16244384687
-
Preclinical and clinical experience with fulvestrant (Faslodex) in postmenopausal women with hormone receptorpositive advanced breast cancer
-
Bundred N. (2005). Preclinical and clinical experience with fulvestrant (Faslodex) in postmenopausal women with hormone receptorpositive advanced breast cancer. Cancer Invest. 23, 173-181.
-
(2005)
Cancer Invest
, vol.23
, pp. 173-181
-
-
Bundred, N.1
-
15
-
-
0034696279
-
The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis meeting
-
Cardiff R.D., Anver M.R., Gusterson B.A., Hennighausen L., Jensen R.A., Merino M.J., Rehm S., Russo J., Tavassoli F.A., Wakefield L.M., Ward J.M. and Green J.E. (2000). The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene 19, 968-988.
-
(2000)
Oncogene
, vol.19
, pp. 968-988
-
-
Cardiff, R.D.1
Anver, M.R.2
Gusterson, B.A.3
Hennighausen, L.4
Jensen, R.A.5
Merino, M.J.6
Rehm, S.7
Russo, J.8
Tavassoli, F.A.9
Wakefield, L.M.10
Ward, J.M.11
Green, J.E.12
-
16
-
-
0038338443
-
Breast cancer risk among the survivors of atomic bomb and patients exposed to therapeutic ionising radiation
-
Carmichael A., Sami A.S. and Dixon J.M. (2003). Breast cancer risk among the survivors of atomic bomb and patients exposed to therapeutic ionising radiation. Eur. J. Surg. Oncol. 29, 475-479.
-
(2003)
Eur. J. Surg. Oncol
, vol.29
, pp. 475-479
-
-
Carmichael, A.1
Sami, A.S.2
Dixon, J.M.3
-
17
-
-
77953807903
-
Cancer as a reprogramming-like disease: Implications in tumor development and treatment
-
Castellanos A, Vicente-Dueñas C, Campos-Sánchez E, Cruz JJ, García-Criado FJ, García-Cenador MB, Lazo PA, Pérez-Losada J and Sánchez-García I. (2010). Cancer as a reprogramming-like disease: implications in tumor development and treatment. Semin. Cancer Biol. 20(2), 93-97.
-
(2010)
Semin. Cancer Biol
, vol.20
, Issue.2
, pp. 93-97
-
-
Castellanos, A.1
Vicente-Dueñas, C.2
Campos-Sánchez, E.3
Cruz, J.J.4
García-Criado, F.J.5
García-Cenador, M.B.6
Lazo, P.A.7
Pérez-Losada, J.8
Sánchez-García, I.9
-
18
-
-
24344500211
-
Initial sequence of the chimpanzee genome and comparison with the human genome
-
Chimpanzee Sequencing and Analysis Consortium
-
Chimpanzee Sequencing and Analysis Consortium. (2005). Initial sequence of the chimpanzee genome and comparison with the human genome. Nature 437, 69-87.
-
(2005)
Nature
, vol.437
, pp. 69-87
-
-
-
19
-
-
11144242211
-
Timeline: Chemotherapy and the war on cancer
-
Chabner B.A. and Roberts T.G. Jr (2005). Timeline: Chemotherapy and the war on cancer. Nat. Rev. Cancer 5, 65-72.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 65-72
-
-
Chabner, B.A.1
Roberts Jr., T.G.2
-
21
-
-
14944367962
-
Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment
-
Chu S., Xu H., Shah N.P., Snyder D.S., Forman S.J., Sawyers C.L. and Bhatia R. (2005). Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment. Blood 105, 2093-2098.
-
(2005)
Blood
, vol.105
, pp. 2093-2098
-
-
Chu, S.1
Xu, H.2
Shah, N.P.3
Snyder, D.S.4
Forman, S.J.5
Sawyers, C.L.6
Bhatia, R.7
-
22
-
-
13244298130
-
Self-renewal and solid-tumor stem cells
-
Clarke M.F. (2005). Self-renewal and solid-tumor stem cells. Biol. Blood Marrow Transplant. 11, 14-16.
-
(2005)
Biol. Blood Marrow Transplant
, vol.11
, pp. 14-16
-
-
Clarke, M.F.1
-
23
-
-
67650173322
-
B-cell acute lymphoblastic leukaemia: Towards understanding its cellular origin
-
Cobaleda C, and Sánchez-García I. (2009). B-cell acute lymphoblastic leukaemia: towards understanding its cellular origin. Bioessays 31, 600-609.
-
(2009)
Bioessays
, vol.31
, pp. 600-609
-
-
Cobaleda, C.1
Sánchez-García, I.2
-
24
-
-
0034141934
-
A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia
-
Cobaleda C., Gutierrez-Cianca N., Perez-Losada J., Flores T., Garcia-Sanz R., Gonzalez M. and Sanchez-Garcia I. (2000). A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia. Blood 95, 1007-1013.
-
(2000)
Blood
, vol.95
, pp. 1007-1013
-
-
Cobaleda, C.1
Gutierrez-Cianca, N.2
Perez-Losada, J.3
Flores, T.4
Garcia-Sanz, R.5
Gonzalez, M.6
Sanchez-Garcia, I.7
-
25
-
-
14544293557
-
Hormone therapy in breast cancer: The end of tamoxifen?
-
Delozier T. (2005). Hormone therapy in breast cancer: the end of tamoxifen? Bull Cancer 92, 142-150.
-
(2005)
Bull Cancer
, vol.92
, pp. 142-150
-
-
Delozier, T.1
-
26
-
-
0037076342
-
Initiating oncogenic event determines geneexpression patterns of human breast cancer models
-
Desai K.V., Xiao N., Wang W., Gangi L., Greene J., Powell J.I., Dickson R., Furth P., Hunter K., Kucherlapati R., Simon R., Liu E.T. and Green J.E. (2002). Initiating oncogenic event determines geneexpression patterns of human breast cancer models. Proc. Natl. Acad. Sci. USA 99, 6967-6972.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6967-6972
-
-
Desai, K.V.1
Xiao, N.2
Wang, W.3
Gangi, L.4
Greene, J.5
Powell, J.I.6
Dickson, R.7
Furth, P.8
Hunter, K.9
Kucherlapati, R.10
Simon, R.11
Liu, E.T.12
Green, J.E.13
-
27
-
-
27744519434
-
Bioinformatics toolbox for narrowing rodent quantitative trait loci
-
DiPetrillo K., Wang X., Stylianou I.M. and Paigen B. (2005). Bioinformatics toolbox for narrowing rodent quantitative trait loci. Trends Genet. 21, 683-692.
-
(2005)
Trends Genet
, vol.21
, pp. 683-692
-
-
Dipetrillo, K.1
Wang, X.2
Stylianou, I.M.3
Paigen, B.4
-
28
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker B.J., Talpaz M., Resta D.J., Peng B., Buchdunger E., Ford J.M., Lydon N.B., Kantarjian H., Capdeville R., Ohno-Jones S. and Sawyers C.L. (2001). Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 344, 1031-1037.
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
29
-
-
0037648348
-
The case for early detection
-
Etzioni R., Urban N., Ramsey S., McIntosh M., Schwartz S., Reid B., Radich J., Anderson G. and Hartwell L. (2003). The case for early detection. Nat. Rev. Cancer 3, 243-252.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 243-252
-
-
Etzioni, R.1
Urban, N.2
Ramsey, S.3
McIntosh, M.4
Schwartz, S.5
Reid, B.6
Radich, J.7
Anderson, G.8
Hartwell, L.9
-
30
-
-
0042093747
-
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human
-
Ewart-Toland A., Briassouli P., de Koning J.P., Mao J.H., Yuan J., Chan F., MacCarthy-Morrogh L., Ponder B.A., Nagase H., Burn J., Ball S., Almeida M., Linardopoulos S., and Balmain A. (2003). Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat. Genet. 34, 403-412.
-
(2003)
Nat. Genet
, vol.34
, pp. 403-412
-
-
Ewart-Toland, A.1
Briassouli, P.2
de Koning, J.P.3
Mao, J.H.4
Yuan, J.5
Chan, F.6
Maccarthy-Morrogh, L.7
Ponder, B.A.8
Nagase, H.9
Burn, J.10
Ball, S.11
Almeida, M.12
Linardopoulos, S.13
Balmain, A.14
-
31
-
-
24944573674
-
Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: A meta-analysis of multiple cancer types
-
Ewart-Toland A., Dai Q., Gao Y.T., Nagase H., Dunlop M.G., Farrington S.M., Barnetson R.A., Anton-Culver H., Peel D., Ziogas A., Lin D., Miao X., Sun T., Ostrander E.A., Stanford J.L., Langlois M., Chan J.M., Yuan J., Harris C.C., Bowman E.D., Clayman G.L., Lippman S.M., Lee J.J., Zheng W. and Balmain A. (2005). Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types. Carcinogenesis 26, 1368-1373.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1368-1373
-
-
Ewart-Toland, A.1
Dai, Q.2
Gao, Y.T.3
Nagase, H.4
Dunlop, M.G.5
Farrington, S.M.6
Barnetson, R.A.7
Anton-Culver, H.8
Peel, D.9
Ziogas, A.10
Lin, D.11
Miao, X.12
Sun, T.13
Ostrander, E.A.14
Stanford, J.L.15
Langlois, M.16
Chan, J.M.17
Yuan, J.18
Harris, C.C.19
Bowman, E.D.20
Clayman, G.L.21
Lippman, S.M.22
Lee, J.J.23
Zheng, W.24
Balmain, A.25
more..
-
32
-
-
34548295740
-
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains
-
Frazer K.A., Eskin E., Kang H.M., Bogue M.A., Hinds D.A., Beilharz E.J., Gupta R.V., Montgomery J., Morenzoni M.M., Nilsen G.B., Pethiyagoda C.L., Stuve L.L., Johnson F.M., Daly M.J., Wade C.M. and Cox D.R. (2007). A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature 448, 1050-1053.
-
(2007)
Nature
, vol.448
, pp. 1050-1053
-
-
Frazer, K.A.1
Eskin, E.2
Kang, H.M.3
Bogue, M.A.4
Hinds, D.A.5
Beilharz, E.J.6
Gupta, R.V.7
Montgomery, J.8
Morenzoni, M.M.9
Nilsen, G.B.10
Pethiyagoda, C.L.11
Stuve, L.L.12
Johnson, F.M.13
Daly, M.J.14
Wade, C.M.15
Cox, D.R.16
-
34
-
-
0036090222
-
Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro
-
Graham S.M., Jorgensen H.G., Allan E., Pearson C., Alcorn M.J., Richmond L. and Holyoake T.L. (2002). Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood 99, 319-325.
-
(2002)
Blood
, vol.99
, pp. 319-325
-
-
Graham, S.M.1
Jorgensen, H.G.2
Allan, E.3
Pearson, C.4
Alcorn, M.J.5
Richmond, L.6
Holyoake, T.L.7
-
35
-
-
0029867398
-
Is telomerase activity in cancer due to selection of stem cells and differentiation arrest?
-
Greaves M. (1996). Is telomerase activity in cancer due to selection of stem cells and differentiation arrest? Trends Genet. 12, 127-128.
-
(1996)
Trends Genet
, vol.12
, pp. 127-128
-
-
Greaves, M.1
-
36
-
-
14644443626
-
The promise of genetically engineered mice for cancer prevention studies
-
Green J.E. and Hudson T. (2005). The promise of genetically engineered mice for cancer prevention studies. Nat. Rev. Cancer 5, 184-198.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 184-198
-
-
Green, J.E.1
Hudson, T.2
-
37
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D. and Weinberg R.A. (2000). The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
38
-
-
0026452949
-
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
-
Hartwell L. (1992). Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71, 543-546.
-
(1992)
Cell
, vol.71
, pp. 543-546
-
-
Hartwell, L.1
-
39
-
-
34548151293
-
Medical chemistry to spy cancer stem cells from outside the body
-
Herranz M and Sánchez-García I. (2007). Medical chemistry to spy cancer stem cells from outside the body. Mini Rev. Med. Chem. 7, 781-791.
-
(2007)
Mini Rev. Med. Chem
, vol.7
, pp. 781-791
-
-
Herranz, M.1
Sánchez-García, I.2
-
40
-
-
0037836126
-
Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanolinduced activation
-
Hitzemann R., Malmanger B., Cooper S., Coulombe S., Reed C., Demarest K., Koyner J., Cipp L., Flint J., Talbot C., Rademacher B., Buck K. and McCaughran J. Jr (2002). Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanolinduced activation. Genes Brain Behav. 1, 214-222.
-
(2002)
Genes Brain Behav
, vol.1
, pp. 214-222
-
-
Hitzemann, R.1
Malmanger, B.2
Cooper, S.3
Coulombe, S.4
Reed, C.5
Demarest, K.6
Koyner, J.7
Cipp, L.8
Flint, J.9
Talbot, C.10
Rademacher, B.11
Buck, K.12
McCaughran Jr., J.13
-
41
-
-
57449115476
-
The future of mouse QTL mapping to diagnose disease in mice in the age of whole-genome association studies
-
Hunter K.W. and Crawford N.P. (2008). The future of mouse QTL mapping to diagnose disease in mice in the age of whole-genome association studies. Annu. Rev. Genet. 42, 131-141.
-
(2008)
Annu. Rev. Genet
, vol.42
, pp. 131-141
-
-
Hunter, K.W.1
Crawford, N.P.2
-
42
-
-
0037994177
-
Genetic background is an important determinant of metastatic potential
-
author reply 25
-
Hunter K., Welch D.R. and Liu E.T. (2003). Genetic background is an important determinant of metastatic potential. Nat. Genet. 34, 23-24; author reply 25.
-
(2003)
Nat. Genet
, vol.34
, pp. 23-24
-
-
Hunter, K.1
Welch, D.R.2
Liu, E.T.3
-
43
-
-
0031953260
-
The mutation rate and cance
-
Jackson A.L. and Loeb L.A. (1998). The mutation rate and cancer. Genetics 148, 1483-1490.
-
(1998)
Genetics
, vol.148
-
-
Jackso, A.L.1
Loe, L.A.2
-
44
-
-
0035400051
-
Genetical genomics: The added value from segregation
-
Jansen R.C. and Nap J.P. (2001). Genetical genomics: the added value from segregation. Trends Genet. 17, 388-391.
-
(2001)
Trends Genet
, vol.17
, pp. 388-391
-
-
Jansen, R.C.1
Nap, J.P.2
-
45
-
-
13844266349
-
Aromatase inhibitors in the treatment of early and advanced breast cancer
-
Joensuu H., Ejlertsen B., Lonning P.E. and Rutqvist L.E. (2005). Aromatase inhibitors in the treatment of early and advanced breast cancer. Acta Oncol. 44, 23-31.
-
(2005)
Acta Oncol
, vol.44
, pp. 23-31
-
-
Joensuu, H.1
Ejlertsen, B.2
Lonning, P.E.3
Rutqvist, L.E.4
-
46
-
-
2042458747
-
Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials
-
Johnson J.I., Decker S., Zaharevitz D., Rubinstein L.V., Venditti J.M., Schepartz S., Kalyandrug S., Christian M., Arbuck S., Hollingshead M. and Sausville E.A. (2001). Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials. Br. J. Cancer 84, 1424-1431.
-
(2001)
Br. J. Cancer
, vol.84
, pp. 1424-1431
-
-
Johnson, J.I.1
Decker, S.2
Zaharevitz, D.3
Rubinstein, L.V.4
Venditti, J.M.5
Schepartz, S.6
Kalyandrug, S.7
Christian, M.8
Arbuck, S.9
Hollingshead, M.10
Sausville, E.A.11
-
47
-
-
2042437650
-
International Human Genome Sequencing Consortium Initial sequencing and analysis of the human genome
-
Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Devon K., Dewar K., Doyle M., FitzHugh W., Funke R., Gage D., Harris K., Heaford A., Howland J., Kann L., Lehoczky J., LeVine R., McEwan P., McKernan K., Meldrim J., Mesirov J.P., Miranda C., Morris W., Naylor J., Raymond C., Rosetti M., Santos R., Sheridan A., Sougnez C., Stange-Thomann N., Stojanovic N., Subramanian A., Wyman D., Rogers J., Sulston J., Ainscough R., Beck S., Bentley D., Burton J., Clee C., Carter N., Coulson A., Deadman R., Deloukas P., Dunham A., Dunham I., Durbin R., French L., Grafham D., Gregory S., Hubbard T., Humphray S., Hunt A., Jones M., Lloyd C., McMurray A., Matthews L., Mercer S., Milne S., Mullikin J.C., Mungall A., Plumb R., Ross M., Shownkeen R., Sims S., Waterston R.H., Wilson R.K., Hillier L.W., McPherson J.D., Marra M.A., Mardis E.R., Fulton L.A., Chinwalla A.T., Pepin K.H., Gish W.R., Chissoe S.L., Wendl M.C., Delehaunty K.D., Miner T.L., Delehaunty A., Kramer J.B., Cook L.L., Fulton R.S., Johnson D.L., Minx P.J., Clifton S.W., Hawkins T., Branscomb E., Predki P., Richardson P., Wenning S., Slezak T., Doggett N., Cheng J.F., Olsen A., Lucas S., Elkin C., Uberbacher E., Frazier M., Gibbs R.A., Muzny D.M., Scherer S.E., Bouck J.B., Sodergren E.J., Worley K.C., Rives C.M., Gorrell J.H., Metzker M.L., Naylor S.L., Kucherlapati R.S., Nelson D.L., Weinstock G.M., Sakaki Y., Fujiyama A., Hattori M., Yada T., Toyoda A., Itoh T., Kawagoe C., Watanabe H., Totoki Y., Taylor T., Weissenbach J., Heilig R., Saurin W., Artiguenave F., Brottier P., Bruls T., Pelletier E., Robert C., Wincker P., Smith D.R., Doucette-Stamm L., Rubenfield M., Weinstock K., Lee H.M., Dubois J., Rosenthal A., Platzer M., Nyakatura G., Taudien S., Rump A., Yang H., Yu J., Wang J., Huang G., Gu J., Hood L., Rowen L., Madan A., Qin S., Davis R.W., Federspiel N.A., Abola A.P., Proctor M.J., Myers R.M., Schmutz J., Dickson M., Grimwood J., Cox D.R., Olson M.V., Kaul R., Raymond C., Shimizu N., Kawasaki K., Minoshima S., Evans G.A., Athanasiou M., Schultz R., Roe B.A., Chen F., Pan H., Ramser J., Lehrach H., Reinhardt R., McCombie W.R., de la Bastide M., Dedhia N., Blöcker H., Hornischer K., Nordsiek G., Agarwala R., Aravind L., Bailey J.A., Bateman A., Batzoglou S., Birney E., Bork P., Brown D.G., Burge C.B., Cerutti L., Chen H.C., Church D., Clamp M., Copley R.R., Doerks T., Eddy S.R., Eichler E.E., Furey T.S., Galagan J., Gilbert J.G., Harmon C., Hayashizaki Y., Haussler D., Hermjakob H., Hokamp K., Jang W., Johnson L.S., Jones T.A., Kasif S., Kaspryzk A., Kennedy S., Kent W.J., Kitts P., Koonin E.V., Korf I., Kulp D., Lancet D., Lowe T.M., McLysaght A., Mikkelsen T., Moran J.V., Mulder N., Pollara V.J., Ponting C.P., Schuler G., Schultz J., Slater G., Smit A.F., Stupka E., Szustakowski J., Thierry-Mieg D., Thierry-Mieg J., Wagner L., Wallis J., Wheeler R., Williams A., Wolf Y.I., Wolfe K.H., Yang S.P., Yeh R.F., Collins F., Guyer M.S., Peterson J., Felsenfeld A., Wetterstrand K.A., Patrinos A., Morgan M.J., de Jong P., Catanese J.J., Osoegawa K., Shizuya H., Choi S., Chen Y.J.; International Human Genome Sequencing Consortium. (2001). Initial sequencing and analysis of the human genome. Nature 409, 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
Fitzhugh, W.10
Funke, R.11
Gage, D.12
Harris, K.13
Heaford, A.14
Howland, J.15
Kann, L.16
Lehoczky, J.17
Levine, R.18
McEwan, P.19
McKernan, K.20
Meldrim, J.21
Mesirov, J.P.22
Miranda, C.23
Morris, W.24
Naylor, J.25
Raymond, C.26
Rosetti, M.27
Santos, R.28
Sheridan, A.29
Sougnez, C.30
Stange-Thomann, N.31
Stojanovic, N.32
Subramanian, A.33
Wyman, D.34
Rogers, J.35
Sulston, J.36
Ainscough, R.37
Beck, S.38
Bentley, D.39
Burton, J.40
Clee, C.41
Carter, N.42
Coulson, A.43
Deadman, R.44
Deloukas, P.45
Dunham, A.46
Dunham, I.47
Durbin, R.48
French, L.49
Grafham, D.50
Gregory, S.51
Hubbard, T.52
Humphray, S.53
Hunt, A.54
Jones, M.55
Lloyd, C.56
McMurray, A.57
Matthews, L.58
Mercer, S.59
Milne, S.60
Mullikin, J.C.61
Mungall, A.62
Plumb, R.63
Ross, M.64
Shownkeen, R.65
Sims, S.66
Waterston, R.H.67
Wilson, R.K.68
Hillier, L.W.69
McPherson, J.D.70
Marra, M.A.71
Mardis, E.R.72
Fulton, L.A.73
Chinwalla, A.T.74
Pepin, K.H.75
Gish, W.R.76
Chissoe, S.L.77
Wendl, M.C.78
Delehaunty, K.D.79
Miner, T.L.80
Delehaunty, A.81
Kramer, J.B.82
Cook, L.L.83
Fulton, R.S.84
Johnson, D.L.85
Minx, P.J.86
Clifton, S.W.87
Hawkins, T.88
Branscomb, E.89
Predki, P.90
Richardson, P.91
Wenning, S.92
Slezak, T.93
Doggett, N.94
Cheng, J.F.95
Olsen, A.96
Lucas, S.97
Elkin, C.98
Uberbacher, E.99
more..
-
48
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T., Sirard C., Vormoor J., Murdoch B., Hoang T., Caceres-Cortes J., Minden M., Paterson B., Caligiuri M.A. and Dick J.E. (1994). A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367, 645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
49
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer C., Kinzler K.W. and Vogelstein B. (1998). Genetic instabilities in human cancers. Nature 396, 643-649.
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
50
-
-
4344649384
-
Genetically modified mouse models for pharmacogenomic research
-
Liggett S.B. (2004). Genetically modified mouse models for pharmacogenomic research. Nat. Rev. Genet. 5, 657-663.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 657-663
-
-
Liggett, S.B.1
-
51
-
-
28644447707
-
Genome sequence, comparative analysis and haplotype structure of the domestic dog
-
Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B., Kamal M., Clamp M., Chang J.L., Kulbokas E.J. 3rd, Zody M.C., Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F., Smith D.R., DeJong P.J., Kirkness E., Alvarez P., Biagi T., Brockman W., Butler J., Chin C.W., Cook A., Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M., Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L., Koepfli K.P., Parker H.G., Pollinger J.P., Searle S.M., Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A., Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P., Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L., Bachantsang P., Barry A., Bayul T., Benamara M., Berlin A., Bessette D., Blitshteyn B., Bloom T., Blye J., Boguslavskiy L., Bonnet C., Boukhgalter B., Brown A., Cahill P., Calixte N., Camarata J., Cheshatsang Y., Chu J., Citroen M., Collymore A., Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., Dhargay N., Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N., Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S., Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K., Foley C., Franke A., Friedrich D., Gage D., Garber M., Gearin G., Giannoukos G., Goode T., Goyette A., Graham J., Grandbois E., Gyaltsen K., Hafez N., Hagopian D., Hagos B., Hall J., Healy C., Hegarty R., Honan T., Horn A., Houde N., Hughes L., Hunnicutt L., Husby M., Jester B., Jones C., Kamat A., Kanga B., Kells C., Khazanovich D., Kieu A.C., Kisner P., Kumar M., Lance K., Landers T., Lara M., Lee W., Leger J.P., Lennon N., Leuper L., LeVine S., Liu J., Liu X., Lokyitsang Y., Lokyitsang T., Lui A., Macdonald J., Major J., Marabella R., Maru K., Matthews C., McDonough S., Mehta T., Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., Miller K., Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., Naylor J., Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N., Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K., Osman S., Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F., Priest M., Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C., Rege F., Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S., Sharpe T., Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J., Smith C., Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S., Thoulutsang D., Thoulutsang Y., Topham K., Topping I., Tsamla T., Vassiliev H., Venkataraman V., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., Wilson A., Yadav S., Yang S., Yang X., Young G., Yu Q., Zainoun J., Zembek L., Zimmer A. and Lander E.S. (2005). Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438, 803-819.
-
(2005)
Nature
, vol.438
, pp. 803-819
-
-
Lindblad-Toh, K.1
Wade, C.M.2
Mikkelsen, T.S.3
Karlsson, E.K.4
Jaffe, D.B.5
Kamal, M.6
Clamp, M.7
Chang, J.L.8
Kulbokas III., E.J.9
Zody, M.C.10
Mauceli, E.11
Xie, X.12
Breen, M.13
Wayne, R.K.14
Ostrander, E.A.15
Ponting, C.P.16
Galibert, F.17
Smith, D.R.18
Dejong, P.J.19
Kirkness, E.20
Alvarez, P.21
Biagi, T.22
Brockman, W.23
Butler, J.24
Chin, C.W.25
Cook, A.26
Cuff, J.27
Daly, M.J.28
Decaprio, D.29
Gnerre, S.30
Grabherr, M.31
Kellis, M.32
Kleber, M.33
Bardeleben, C.34
Goodstadt, L.35
Heger, A.36
Hitte, C.37
Kim, L.38
Koepfli, K.P.39
Parker, H.G.40
Pollinger, J.P.41
Searle, S.M.42
Sutter, N.B.43
Thomas, R.44
Webber, C.45
Baldwin, J.46
Abebe, A.47
Abouelleil, A.48
Aftuck, L.49
Ait-Zahra, M.50
Aldredge, T.51
Allen, N.52
An, P.53
Anderson, S.54
Antoine, C.55
Arachchi, H.56
Aslam, A.57
Ayotte, L.58
Bachantsang, P.59
Barry, A.60
Bayul, T.61
Benamara, M.62
Berlin, A.63
Bessette, D.64
Blitshteyn, B.65
Bloom, T.66
Blye, J.67
Boguslavskiy, L.68
Bonnet, C.69
Boukhgalter, B.70
Brown, A.71
Cahill, P.72
Calixte, N.73
Camarata, J.74
Cheshatsang, Y.75
Chu, J.76
Citroen, M.77
Collymore, A.78
Cooke, P.79
Dawoe, T.80
Daza, R.81
Decktor, K.82
Degray, S.83
Dhargay, N.84
Dooley, K.85
Dooley, K.86
Dorje, P.87
Dorjee, K.88
Dorris, L.89
Duffey, N.90
Dupes, A.91
Egbiremolen, O.92
Elong, R.93
Falk, J.94
Farina, A.95
Faro, S.96
Ferguson, D.97
Ferreira, P.98
Fisher, S.99
more..
-
52
-
-
0033057859
-
Genetically engineered mice in drug development
-
Livingston J.N. (1999). Genetically engineered mice in drug development. J. Intern. Med. 245, 627-635.
-
(1999)
J. Intern. Med
, vol.245
, pp. 627-635
-
-
Livingston, J.N.1
-
53
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
Loeb L.A. (1991). Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51, 3075-3079.
-
(1991)
Cancer Res
, vol.51
, pp. 3075-3079
-
-
Loeb, L.A.1
-
54
-
-
0035230102
-
Quantitative trait loci in Drosophila
-
Mackay T.F. (2001). Quantitative trait loci in Drosophila. Nat. Rev. Genet. 2, 11-20.
-
(2001)
Nat. Rev. Genet
, vol.2
, pp. 11-20
-
-
Mackay, T.F.1
-
55
-
-
14944380168
-
Reporter mice and drug discovery and development
-
Maggi A. and Ciana P. (2005). Reporter mice and drug discovery and development. Nat. Rev. Drug Discov. 4, 249-255.
-
(2005)
Nat. Rev. Drug Discov
, vol.4
, pp. 249-255
-
-
Maggi, A.1
Ciana, P.2
-
56
-
-
0037338436
-
Molecular imaging in living subjects: Seeing fundamental biological processes in a new light
-
Massoud T.F. and Gambhir S.S. (2003). Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 17, 545-580.
-
(2003)
Genes Dev
, vol.17
, pp. 545-580
-
-
Massoud, T.F.1
Gambhir, S.S.2
-
57
-
-
1542283717
-
Characterization of clonogenic multiple myeloma cells
-
Matsui W., Huff C.A., Wang Q., Malehorn M.T., Barber J., Tanhehco Y., Smith B.D., Civin C.I. and Jones R.J. (2004). Characterization of clonogenic multiple myeloma cells. Blood 103, 2332-2336.
-
(2004)
Blood
, vol.103
, pp. 2332-2336
-
-
Matsui, W.1
Huff, C.A.2
Wang, Q.3
Malehorn, M.T.4
Barber, J.5
Tanhehco, Y.6
Smith, B.D.7
Civin, C.I.8
Jones, R.J.9
-
58
-
-
0035344667
-
STI571: A gene product-targeted therapy for leukemia
-
Mauro M.J. and Druker B.J. (2001a). STI571: a gene product-targeted therapy for leukemia. Curr. Oncol. Rep. 3, 223-227.
-
(2001)
Curr. Oncol. Rep
, vol.3
, pp. 223-227
-
-
Mauro, M.J.1
Druker, B.J.2
-
59
-
-
0034951384
-
STI571: Targeting BCR-ABL as therapy for CML
-
Mauro M.J. and Druker B.J. (2001b). STI571: targeting BCR-ABL as therapy for CML. Oncologist 6, 233-238.
-
(2001)
Oncologist
, vol.6
, pp. 233-238
-
-
Mauro, M.J.1
Druker, B.J.2
-
60
-
-
18844370441
-
Epidermal growth factor receptor and signal transduction: Potential targets for anti-cancer therapy
-
Pal S.K. and Pegram M. (2005). Epidermal growth factor receptor and signal transduction: potential targets for anti-cancer therapy. Anticancer Drugs 16, 483-494.
-
(2005)
Anticancer Drugs
, vol.16
, pp. 483-494
-
-
Pal, S.K.1
Pegram, M.2
-
62
-
-
58149333204
-
Cancer induction by restriction of oncogene expression to the stem cell compartment
-
Pérez-Caro M, Cobaleda C, González-Herrero I, Vicente-Dueñas C, Bermejo-Rodríguez C, Sánchez-Beato M, Orfao A, Pintado B, Flores T, Sánchez-Martín M, Jiménez R, Piris MA and Sánchez-García I. (2009). Cancer induction by restriction of oncogene expression to the stem cell compartment. EMBO J. 28, 8-20.
-
(2009)
EMBO J
, vol.28
, pp. 8-20
-
-
Pérez-Caro, M.1
Cobaleda, C.2
González-Herrero, I.3
Vicente-Dueñas, C.4
Bermejo-Rodríguez, C.5
Sánchez-Beato, M.6
Orfao, A.7
Pintado, B.8
Flores, T.9
Sánchez-Martín, M.10
Jiménez, R.11
Piris, M.A.12
Sánchez-García, I.13
-
63
-
-
1942422737
-
Integrating pharmacology and in vivo cancer models in preclinical and clinical drug development
-
Peterson J.K. and Houghton P.J. (2004). Integrating pharmacology and in vivo cancer models in preclinical and clinical drug development. Eur. J. Cancer 40, 837-844.
-
(2004)
Eur. J. Cancer
, vol.40
, pp. 837-844
-
-
Peterson, J.K.1
Houghton, P.J.2
-
64
-
-
68949216248
-
Systems genetics analysis of cancer susceptibility: From mouse models to humans
-
Quigley D. and Balmain A. (2009). Systems genetics analysis of cancer susceptibility: from mouse models to humans. Nat. Rev. Genet 10, 651-657.
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 651-657
-
-
Quigley, D.1
Balmain, A.2
-
65
-
-
63649143888
-
Genetic architecture of mouse skin inflammation and tumour susceptibility
-
Quigley D.A., To M.D., Perez-Losada J., Pelorosso F.G., Mao J.H., Nagase H., Ginzinger D.G. and Balmain A. (2009). Genetic architecture of mouse skin inflammation and tumour susceptibility. Nature 458, 505-508.
-
(2009)
Nature
, vol.458
, pp. 505-508
-
-
Quigley, D.A.1
To, M.D.2
Perez-Losada, J.3
Pelorosso, F.G.4
Mao, J.H.5
Nagase, H.6
Ginzinger, D.G.7
Balmain, A.8
-
66
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F. and Weissman I.L. (2001). Stem cells, cancer, and cancer stem cells. Nature 414, 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
67
-
-
0037313516
-
Molecular imaging in drug discovery and development
-
Rudin M. and Weissleder R. (2003). Molecular imaging in drug discovery and development. Nat. Rev. Drug Discov. 2, 123-131.
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, pp. 123-131
-
-
Rudin, M.1
Weissleder, R.2
-
68
-
-
0036559186
-
Gli and hedgehog in cancer: Tumours, embryos and stem cells
-
Ruiz i Altaba A., Sanchez P. and Dahmane N. (2002). Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat. Rev. Cancer 2, 361-372.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 361-372
-
-
Ruiz i Altaba, A.1
Sanchez, P.2
Dahmane, N.3
-
69
-
-
0028934944
-
Gene rearrangement in acute non-lymphoblastic leukaemia: Correlation with morphological and immunophenotypic characteristics of blast cells
-
Sanchez I., San Miguel J.F., Corral J., Martin C., Perez R., Gonzalez M., Canizo M.C., Orfao A. and Gonzalez-Sarmiento R. (1995). Gene rearrangement in acute non-lymphoblastic leukaemia: correlation with morphological and immunophenotypic characteristics of blast cells. Br. J. Haematol 89, 104-109.
-
(1995)
Br. J. Haematol
, vol.89
, pp. 104-109
-
-
Sanchez, I.1
San Miguel, J.F.2
Corral, J.3
Martin, C.4
Perez, R.5
Gonzalez, M.6
Canizo, M.C.7
Orfao, A.8
Gonzalez-Sarmiento, R.9
-
70
-
-
58349110524
-
The crossroads of oncogenesis and metastasis
-
Sánchez-García I. (2009). The crossroads of oncogenesis and metastasis. N. Engl. J. Med. 360, 297-299.
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 297-299
-
-
Sánchez-García, I.1
-
71
-
-
77953811795
-
Getting to the stem of cancer
-
Sánchez-García I. (2010). Getting to the stem of cancer. Semin. Cancer Biol. 20, 63-64.
-
(2010)
Semin. Cancer Biol
, vol.20
, pp. 63-64
-
-
Sánchez-García, I.1
-
72
-
-
0033020327
-
Immunoglobulin lambda chain gene rearrangement in a case of acute nonlymphoblastic leukemia
-
Sanchez-Garcia, I., San Miguel J.F. and Gonzalez-Sarmiento R. (1999). Immunoglobulin lambda chain gene rearrangement in a case of acute nonlymphoblastic leukemia. Leukemia 13, 485-487.
-
(1999)
Leukemia
, vol.13
, pp. 485-487
-
-
Sanchez-Garcia, I.1
San Miguel, J.F.2
Gonzalez-Sarmiento, R.3
-
73
-
-
36849088519
-
The theoretical basis of cancer-stem-cell-based therapeutics of cancer: Can it be put into practice?
-
Sánchez-García I., Vicente-Dueñas C. and Cobaleda C. (2007). The theoretical basis of cancer-stem-cell-based therapeutics of cancer: can it be put into practice? Bioessays 29, 1269-1280.
-
(2007)
Bioessays
, vol.29
, pp. 1269-1280
-
-
Sánchez-García, I.1
Vicente-Dueñas, C.2
Cobaleda, C.3
-
74
-
-
9244222261
-
Targeted cancer therapy
-
Sawyers C. (2004). Targeted cancer therapy. Nature 432, 294-297.
-
(2004)
Nature
, vol.432
, pp. 294-297
-
-
Sawyers, C.1
-
75
-
-
4644219809
-
Cancer stem cells persist in many cancer cell lines
-
Setoguchi T., Taga T. and Kondo T. (2004). Cancer stem cells persist in many cancer cell lines. Cell Cycle 3, 414-415.
-
(2004)
Cell Cycle
, vol.3
, pp. 414-415
-
-
Setoguchi, T.1
Taga, T.2
Kondo, T.3
-
76
-
-
0001686739
-
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
-
Shah N.P., Nicoll J.M., Nagar B., Gorre M.E., Paquette R.L., Kuriyan J. and Sawyers C.L. (2002). Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2, 117-125.
-
(2002)
Cancer Cell
, vol.2
, pp. 117-125
-
-
Shah, N.P.1
Nicoll, J.M.2
Nagar, B.3
Gorre, M.E.4
Paquette, R.L.5
Kuriyan, J.6
Sawyers, C.L.7
-
77
-
-
0036050013
-
Chronic myelogenous leukemia: Mechanisms underlying disease progression
-
Shet A.S., Jahagirdar B.N. and Verfaillie C.M. (2002). Chronic myelogenous leukemia: mechanisms underlying disease progression. Leukemia 16, 1402-1411.
-
(2002)
Leukemia
, vol.16
, pp. 1402-1411
-
-
Shet, A.S.1
Jahagirdar, B.N.2
Verfaillie, C.M.3
-
78
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh S.K., Clarke I.D., Terasaki M., Bonn V.E., Hawkins C., Squire J. and Dirks P.B. (2003). Identification of a cancer stem cell in human brain tumors. Cancer Res. 63, 5821-5828.
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
79
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon D.J., Leyland-Jones B., Shak S., Fuchs H., Paton V., Bajamonde A., Fleming T., Eiermann W., Wolter J., Pegram M., Baselga J. and Norton L. (2001). Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344, 783-792.
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
80
-
-
33744938412
-
Trends in breast cancer by race and ethnicity: Update 2006
-
Smigal C., Jemal A., Ward E., Cokkinides V., Smith R., Howe H.L. and Thun M. (2006). Trends in breast cancer by race and ethnicity: update 2006. CA Cancer J. Clin. 56, 168-183.
-
(2006)
CA Cancer J. Clin
, vol.56
, pp. 168-183
-
-
Smigal, C.1
Jemal, A.2
Ward, E.3
Cokkinides, V.4
Smith, R.5
Howe, H.L.6
Thun, M.7
-
81
-
-
0023922373
-
Purification and characterization of mouse hematopoietic stem cells
-
Spangrude G.J., Heimfeld S. and Weissman I.L. (1988). Purification and characterization of mouse hematopoietic stem cells. Science 241, 58-62.
-
(1988)
Science
, vol.241
, pp. 58-62
-
-
Spangrude, G.J.1
Heimfeld, S.2
Weissman, I.L.3
-
82
-
-
17644408430
-
Seeing into cells. The promise of in vivo molecular imaging in oncology
-
Sullivan D.C. and Kelloff G. (2005). Seeing into cells. The promise of in vivo molecular imaging in oncology. EMBO Rep. 6, 292-296.
-
(2005)
EMBO Rep
, vol.6
, pp. 292-296
-
-
Sullivan, D.C.1
Kelloff, G.2
-
83
-
-
33746555367
-
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice
-
To M.D., Perez-Losada J., Mao J.H., Hsu J., Jacks T. and Balmain A. (2006). A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice. Nat. Genet. 38, 926-930.
-
(2006)
Nat. Genet
, vol.38
, pp. 926-930
-
-
To, M.D.1
Perez-Losada, J.2
Mao, J.H.3
Hsu, J.4
Jacks, T.5
Balmain, A.6
-
84
-
-
17644382288
-
Critical evaluation of current treatments in metastatic colorectal cancer
-
Venook A. (2005). Critical evaluation of current treatments in metastatic colorectal cancer. Oncologist 10, 250-261.
-
(2005)
Oncologist
, vol.10
, pp. 250-261
-
-
Venook, A.1
-
85
-
-
0035895505
-
The sequence of the human genome
-
Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I, Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov GV., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigó R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A. and Zhu X. (2001). The sequence of the human genome. Science 291, 1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
Gocayne, J.D.11
Amanatides, P.12
Ballew, R.M.13
Huson, D.H.14
Wortman, J.R.15
Zhang, Q.16
Kodira, C.D.17
Zheng, X.H.18
Chen, L.19
Skupski, M.20
Subramanian, G.21
Thomas, P.D.22
Zhang, J.23
Gabor Miklos, G.L.24
Nelson, C.25
Broder, S.26
Clark, A.G.27
Nadeau, J.28
McKusick, V.A.29
Zinder, N.30
Levine, A.J.31
Roberts, R.J.32
Simon, M.33
Slayman, C.34
Hunkapiller, M.35
Bolanos, R.36
Delcher, A.37
Dew, I.38
Fasulo, D.39
Flanigan, M.40
Florea, L.41
Halpern, A.42
Hannenhalli, S.43
Kravitz, S.44
Levy, S.45
Mobarry, C.46
Reinert, K.47
Remington, K.48
Abu-Threideh, J.49
Beasley, E.50
Biddick, K.51
Bonazzi, V.52
Brandon, R.53
more..
-
86
-
-
65949090730
-
Stem-cell driven cancer: Hands-off regulation of cancer development
-
Vicente-Dueñas C., Pérez-Caro M., Abollo-Jiménez F., Cobaleda C. and Sánchez-García I. (2009). Stem-cell driven cancer: hands-off regulation of cancer development. Cell Cycle 8, 1314-1318.
-
(2009)
Cell Cycle
, vol.8
, pp. 1314-1318
-
-
Vicente-Dueñas, C.1
Pérez-Caro, M.2
Abollo-Jiménez, F.3
Cobaleda, C.4
Sánchez-García, I.5
-
88
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
Waterston R.H., Lindblad-Toh K., Birney E., Rogers J., Abril J.F., Agarwal P., Agarwala R., Ainscough R., Alexandersson M., An P., Antonarakis S.E., Attwood J., Baertsch R., Bailey J., Barlow K., Beck S., Berry E., Birren B., Bloom T., Bork P., Botcherby M., Bray N., Brent M.R., Brown D.G., Brown S.D., Bult C., Burton J., Butler J., Campbell R.D., Carninci P., Cawley S., Chiaromonte F., Chinwalla A.T., Church D.M., Clamp M., Clee C., Collins F.S., Cook L.L., Copley R.R., Coulson A., Couronne O., Cuff J., Curwen V., Cutts T., Daly M., David R., Davies J., Delehaunty K.D., Deri J., Dermitzakis E.T., Dewey C., Dickens N.J., Diekhans M., Dodge S., Dubchak I., Dunn D.M., Eddy S.R., Elnitski L., Emes R.D., Eswara P., Eyras E., Felsenfeld A., Fewell G.A., Flicek P., Foley K., Frankel W.N., Fulton L.A., Fulton R.S., Furey T.S., Gage D., Gibbs R.A., Glusman G., Gnerre S., Goldman N., Goodstadt L., Grafham D., Graves T.A., Green E.D., Gregory S., Guigó R., Guyer M., Hardison R.C., Haussler D., Hayashizaki Y., Hillier L.W., Hinrichs A., Hlavina W., Holzer T., Hsu F., Hua A., Hubbard T., Hunt A., Jackson I., Jaffe D.B., Johnson L.S., Jones M., Jones T.A., Joy A., Kamal M., Karlsson E.K., Karolchik D., Kasprzyk A., Kawai J., Keibler E., Kells C., Kent W.J., Kirby A., Kolbe D.L., Korf I., Kucherlapati R.S., Kulbokas E.J., Kulp D., Landers T., Leger J.P., Leonard S., Letunic I., Levine R., Li J., Li M., Lloyd C., Lucas S., Ma B., Maglott D.R., Mardis E.R., Matthews L., Mauceli E., Mayer J.H., McCarthy M., McCombie W.R., McLaren S., McLay K., McPherson J.D., Meldrim J., Meredith B., Mesirov J.P., Miller W., Miner T.L., Mongin E., Montgomery K.T., Morgan M., Mott R., Mullikin J.C., Muzny D.M., Nash W.E., Nelson J.O., Nhan M.N., Nicol R., Ning Z., Nusbaum C., O'Connor M.J., Okazaki Y., Oliver K., Overton-Larty E., Pachter L., Parra G., Pepin K.H., Peterson J., Pevzner P., Plumb R., Pohl C.S., Poliakov A., Ponce T.C., Ponting C.P., Potter S., Quail M., Reymond A., Roe B.A., Roskin K.M., Rubin E.M., Rust A.G., Santos R., Sapojnikov V., Schultz B., Schultz J., Schwartz M.S., Schwartz S., Scott C., Seaman S., Searle S., Sharpe T., Sheridan A., Shownkeen R., Sims S., Singer J.B., Slater G., Smit A., Smith D.R., Spencer B., Stabenau A., Stange-Thomann N., Sugnet C., Suyama M., Tesler G., Thompson J., Torrents D., Trevaskis E., Tromp J., Ucla C., Ureta-Vidal A., Vinson J.P., Von Niederhausern A.C., Wade C.M., Wall M., Weber R.J., Weiss R.B., Wendl M.C., West A.P., Wetterstrand K., Wheeler R., Whelan S., Wierzbowski J., Willey D., Williams S., Wilson R.K., Winter E., Worley K.C., Wyman D., Yang S., Yang S.P., Zdobnov E.M., Zody M.C. and Lander E.S. (2002). Initial sequencing and comparative analysis of the mouse genome. Nature 420, 520-562.
-
(2002)
Nature
, vol.420
, pp. 520-562
-
-
Waterston, R.H.1
Lindblad-Toh, K.2
Birney, E.3
Rogers, J.4
Abril, J.F.5
Agarwal, P.6
Agarwala, R.7
Ainscough, R.8
Alexandersson, M.9
An, P.10
Antonarakis, S.E.11
Attwood, J.12
Baertsch, R.13
Bailey, J.14
Barlow, K.15
Beck, S.16
Berry, E.17
Birren, B.18
Bloom, T.19
Bork, P.20
Botcherby, M.21
Bray, N.22
Brent, M.R.23
Brown, D.G.24
Brown, S.D.25
Bult, C.26
Burton, J.27
Butler, J.28
Campbell, R.D.29
Carninci, P.30
Cawley, S.31
Chiaromonte, F.32
Chinwalla, A.T.33
Church, D.M.34
Clamp, M.35
Clee, C.36
Collins, F.S.37
Cook, L.L.38
Copley, R.R.39
Coulson, A.40
Couronne, O.41
Cuff, J.42
Curwen, V.43
Cutts, T.44
Daly, M.45
David, R.46
Davies, J.47
Delehaunty, K.D.48
Deri, J.49
Dermitzakis, E.T.50
Dewey, C.51
Dickens, N.J.52
Diekhans, M.53
Dodge, S.54
Dubchak, I.55
Dunn, D.M.56
Eddy, S.R.57
Elnitski, L.58
Emes, R.D.59
Eswara, P.60
Eyras, E.61
Felsenfeld, A.62
Fewell, G.A.63
Flicek, P.64
Foley, K.65
Frankel, W.N.66
Fulton, L.A.67
Fulton, R.S.68
Furey, T.S.69
Gage, D.70
Gibbs, R.A.71
Glusman, G.72
Gnerre, S.73
Goldman, N.74
Goodstadt, L.75
Grafham, D.76
Graves, T.A.77
Green, E.D.78
Gregory, S.79
Guigó, R.80
Guyer, M.81
Hardison, R.C.82
Haussler, D.83
Hayashizaki, Y.84
Hillier, L.W.85
Hinrichs, A.86
Hlavina, W.87
Holzer, T.88
Hsu, F.89
Hua, A.90
Hubbard, T.91
Hunt, A.92
Jackson, I.93
Jaffe, D.B.94
Johnson, L.S.95
Jones, M.96
Jones, T.A.97
Joy, A.98
Kamal, M.99
more..
-
89
-
-
0036675318
-
Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer
-
Weaver Z., Montagna C., Xu X., Howard T., Gadina M., Brodie S.G., Deng C.X. and Ried T. (2002). Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer. Oncogene 21, 5097-5107.
-
(2002)
Oncogene
, vol.21
, pp. 5097-5107
-
-
Weaver, Z.1
Montagna, C.2
Xu, X.3
Howard, T.4
Gadina, M.5
Brodie, S.G.6
Deng, C.X.7
Ried, T.8
-
90
-
-
0037421584
-
Inheritance and drug response
-
Weinshilboum R. (2003). Inheritance and drug response. N. Engl. J. Med. 348, 529-537.
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 529-537
-
-
Weinshilboum, R.1
-
91
-
-
50849132211
-
Mouse modifier genes in mammary tumorigenesis and metastasis
-
Winter S.F. and Hunter K.W. (2008). Mouse modifier genes in mammary tumorigenesis and metastasis. J. Mammary Gland Biol. Neoplasia 13, 337-342.
-
(2008)
J. Mammary Gland Biol. Neoplasia
, vol.13
, pp. 337-342
-
-
Winter, S.F.1
Hunter, K.W.2
|