Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels

Molecular Systems Biology

Volumn 8, Issue , 2012, Pages

  Frenkel Morgenstern, Milana ^a,d   Danon, Tamar ^a   Christian, Thomas ^b   Igarashi, Takao ^b   Cohen, Lydia ^a   Hou, Ya Ming ^b   Jensen, Lars Juhl ^c  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

cell cycle; non optimal codons; translation regulation; tRNA expression during cell cycle; wobbling

Indexed keywords

GLUTAMYLPROLYLTRANSFER RNA SYNTHETASE; GLYCYLTHREONYLTRANSFER RNA SYNTHETASE; MESSENGER RNA; TRANSFER RNA; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; PROTEIN;

ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CODON; CONCENTRATION (PARAMETERS); GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; MATHEMATICAL MODEL; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; ARABIDOPSIS; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; GENE; GENE EXPRESSION REGULATION; GENETIC CODE; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SCHIZOSACCHAROMYCES; THEORETICAL MODEL;

ARABIDOPSIS; BASE SEQUENCE; BIOLOGICAL CLOCKS; CELL CYCLE; CELL CYCLE PROTEINS; CODON; GENE EXPRESSION REGULATION; GENES; GENETIC CODE; HUMANS; MODELS, BIOLOGICAL; MODELS, THEORETICAL; PROTEINS; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES;

EID: 84857715986     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2012.3     Document Type: Article

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