-
1
-
-
40049093765
-
Systemic lupus erythematosus
-
DOI 10.1056/NEJMra071297
-
Rahman, A.; Isenberg, D.A. Systemic lupus erythematosus. N. Engl. J. Med., 2008,358,929-939. (Pubitemid 351397092)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.9
, pp. 929-939
-
-
Rahman, A.1
Isenberg, D.A.2
-
2
-
-
0035978096
-
Systemic lupus erythematosus
-
DOI 10.1016/S0140-6736(00)04239-2
-
Ruiz-Irastorza, G.; Khamashta, M.A.; Castelino, G., Hughes G.R. Systemic lupus erythematosus. Lancet, 2001, 357, 1027-1032. (Pubitemid 32285401)
-
(2001)
Lancet
, vol.357
, Issue.9261
, pp. 1027-1032
-
-
Ruiz-Irastorza, G.1
Khamashta, M.A.2
Castellino, G.3
Hughes, G.R.V.4
-
3
-
-
80052677307
-
Pathogenesis of systemic lupus erythematosus revisited 2011: End organ resistance to damage, autoantibody initiation and diversification, and HLA-DR
-
Fu, S.M.; Deshmukh, U.S.; Gaskin, F. Pathogenesis of systemic lupus erythematosus revisited 2011: End organ resistance to damage, autoantibody initiation and diversification, and HLA-DR. J Autoimmun. 2011, 37,104-112.
-
(2011)
J Autoimmun.
, vol.37
, pp. 104-112
-
-
Fu, S.M.1
Deshmukh, U.S.2
Gaskin, F.3
-
4
-
-
78650221829
-
Moving towards a cure: Blocking pathogenic an antibodies in systemic lupus erythematosus
-
Diamond, B.; Bloom, O.; Al Abed, Y.; Kowal, C.; Huerta, P.T.; Volpe, B.T. Moving towards a cure: Blocking pathogenic an antibodies in systemic lupus erythematosus. J. Intern. Med., 2011, 269,36-44.
-
(2011)
J. Intern. Med.
, vol.269
, pp. 36-44
-
-
Diamond, B.1
Bloom, O.2
Al Abed, Y.3
Kowal, C.4
Huerta, P.T.5
Volpe, B.T.6
-
5
-
-
78549265981
-
Potential role of IFN alpha in adult lupus
-
Rönnblom, L. Potential role of IFN alpha in adult lupus. Arthritis Res Ther., 2010,12(Suppl 1),S3.
-
(2010)
Arthritis Res Ther.
, vol.12
, Issue.SUPPL. 1
-
-
Rönnblom, L.1
-
6
-
-
0028782615
-
Systemic lupus erythematosus
-
Mills, J.A. Systemic lupus erythematosus. N. Engl. J. Med., 1994, 330, 1871-1879.
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 1871-1879
-
-
Mills, J.A.1
-
7
-
-
54249137345
-
The influence of antimalarial treatment on IL-1beta, IL-6 and TNF-alpha mRNA expression on UVB-irradiated skin in systemic lupus erythematosus
-
Wozniacka, A.; Lesiak, A.; Boncela, J.; Smolarczyk, K.; McCauliffe, D.P.; Sysa-Jedrzejowska A. The influence of antimalarial treatment on IL-1beta, IL-6 and TNF-alpha mRNA expression on UVB-irradiated skin in systemic lupus erythematosus. Br. J. Dermatol. 2008,159, 1124-1130.
-
(2008)
Br. J. Dermatol.
, vol.159
, pp. 1124-1130
-
-
Wozniacka, A.1
Lesiak, A.2
Boncela, J.3
Smolarczyk, K.4
McCauliffe, D.P.5
Sysa-Jedrzejowska, A.6
-
8
-
-
70449727689
-
Biologics as treatment for systemic lupus: Great efforts, sobering results, new challenges
-
Schröder ,J.O.; Zeuner, R.A. Biologics as treatment for systemic lupus: Great efforts, sobering results, new challenges. Curr. Drug. Discov. Technol., 2009;6:252-255.
-
(2009)
Curr. Drug. Discov. Technol.
, vol.6
, pp. 252-255
-
-
Schröder, J.O.1
Zeuner, R.A.2
-
9
-
-
79551477165
-
Current and novel therapeutics in the treatment of systemic lupus erythematosus
-
Yildirim-Toruner, C.; Diamond, B. Current and novel therapeutics in the treatment of systemic lupus erythematosus. J Allergy Clin Immunol., 2011,127,303-12.
-
(2011)
J Allergy Clin Immunol.
, vol.127
, pp. 303-312
-
-
Yildirim-Toruner, C.1
Diamond, B.2
-
10
-
-
78650317840
-
Novel treatments for systemic lupus erythematosus
-
Gayed, M.; Gordon, C. Novel treatments for systemic lupus erythematosus. Curr. Opin. Investig. Drugs., 2010,11,1256-1264.
-
(2010)
Curr. Opin. Investig. Drugs.
, vol.11
, pp. 1256-1264
-
-
Gayed, M.1
Gordon, C.2
-
11
-
-
75649121143
-
The immunological basis of B-cell therapy in systemic lupus erythematosus
-
Mok, M.Y. The immunological basis of B-cell therapy in systemic lupus erythematosus. Int. J. Rheum. Dis., 2010,13,3-11.
-
(2010)
Int. J. Rheum. Dis.
, vol.13
, pp. 3-11
-
-
Mok, M.Y.1
-
12
-
-
79551477165
-
Current and novel therapeutics in the treatment of systemic lupus erythematosus
-
Yildirim-Torune,r C.; Diamond, B. Current and novel therapeutics in the treatment of systemic lupus erythematosus. J. Allergy Clin. Immunol., 2011,127,303-312.
-
(2011)
J. Allergy Clin. Immunol.
, vol.127
, pp. 303-312
-
-
Yildirim-Toruner, C.1
Diamond, B.2
-
13
-
-
0035043278
-
The treatment of lupus with cyclosporin A
-
DOI 10.1191/096120301672970034
-
Griffiths, B.; Emery, P. The treatment of lupus with cyclosporin A. Lupus, 2001, 10,165-170. (Pubitemid 32410072)
-
(2001)
Lupus
, vol.10
, Issue.3
, pp. 165-170
-
-
Griffiths, B.1
Emery, P.2
-
14
-
-
78751549570
-
Regulatory mechanisms of calcineurin phosphatase activity
-
Musson, R.E.; Smit, N.P. Regulatory mechanisms of calcineurin phosphatase activity. Curr. Med. Chem., 2011,18,301-315.
-
(2011)
Curr. Med. Chem.
, vol.18
, pp. 301-315
-
-
Musson, R.E.1
Smit, N.P.2
-
15
-
-
0031926311
-
Clinical efficacy of cyclosporin A neoral in the treatment of paediatric lupus nephritis with heavy proteinuria
-
Fu, L.W; Yang, L.Y.; Chen, W.P.; Lin, C.Y. Clinical efficacy of cyclosporin A neoral in the treatment of paediatric lupus nephritis with heavy proteinuria. Br. J. Rheumatol., 1998,37,217-221.
-
(1998)
Br. J. Rheumatol.
, vol.37
, pp. 217-221
-
-
Fu, L.W.1
Yang, L.Y.2
Chen, W.P.3
Lin, C.Y.4
-
16
-
-
0031020977
-
Long-term treatment of systemic lupus erythematosus with cyclosporin A
-
DOI 10.1002/art.1780400106
-
Caccavo, D.; Lagana, B.; Mitterhofer, A.P.; Ferri, G.M.; Afeltra, A.; Amoroso, A.; Bonomo, L. Long-term treatment of systemic lupus erythematosus with cyclosporin A. Arthritis Rheum., 1997, 40, 27-35. (Pubitemid 27044033)
-
(1997)
Arthritis and Rheumatism
, vol.40
, Issue.1
, pp. 27-35
-
-
Caccavo, D.1
Lagana, B.2
Mitterhofer, A.P.3
Ferri, G.M.4
Afeltra, A.5
Amoroso, A.6
Bonomo, L.7
-
17
-
-
4344664004
-
Treatment of steroid-resistant systemic lupus erythematosus with extremely low dose of cyclosporine A
-
DOI 10.1111/j.1442-200x.2004.01918.x
-
Sakano, T.; Ohta, T.; Kinoshita, Y.; Fjiwara, M.; Wakai, M. Treatment of steroid resistant systemic lupus erythematosus with extremely low dose of cyclosporine A. Pediatr. Int., 2004, 46, 468-470. (Pubitemid 39119164)
-
(2004)
Pediatrics International
, vol.46
, Issue.4
, pp. 468-470
-
-
Sakano, T.1
Ohta, T.2
Kinoshita, Y.3
Fjiwara, M.4
Wakai, M.5
-
18
-
-
34249871364
-
The dynamism of cutaneous lupus erythematosus: Mild discoid lupus erythematosus evolving into SLE with SCLE and treatment-resistant lupus panniculitis
-
DOI 10.1007/s10067-006-0310-6
-
Wozniacka, A.; Salamon, M; Lesiak, A.; McCauliffe, D.P.; Sysa- Jedrzejowska A. The dynamism of cutaneous lupus erythematosus: Mild discoid lupus erythematosus evolving into SLE with SCLE and treatmentresistant lupus panniculitis. Clin Rheumatol. 2007, 26,1176-1179. (Pubitemid 46863973)
-
(2007)
Clinical Rheumatology
, vol.26
, Issue.7
, pp. 1176-1179
-
-
Wozniacka, A.1
Salamon, M.2
Lesiak, A.3
McCauliffe, D.P.4
Sysa-Jedrzejowska, A.5
-
19
-
-
0031982976
-
Effect of extremely low dose cyclosporine treatment on the thrombocytopenia in systemic lupus erythematosus
-
DOI 10.1191/096120398678919660
-
Sugiyama, M.; Ogasawara, H.; Kaneko, H.; Hishikawa, T.; Sekigawa, I.; Iida, N.; Hashimoto, H.; Hirose, S. Effect of extremely low dose cyclosporine treatment on the thrombocytopenia in systemic lupus erythematosus. Lupus, 1998, 7, 53-56. (Pubitemid 28052664)
-
(1998)
Lupus
, vol.7
, Issue.1
, pp. 53-56
-
-
Sugiyama, M.1
Ogasawara, H.2
Kaneko, H.3
Hishikawa, T.4
Sekigawa, I.5
Iida, N.6
Hashimoto, H.7
Hirose, S.8
-
20
-
-
33644755651
-
Efficacy of cyclosporin-A in the long-term management of thrombocytopenia associated with systemic lupus erythematosus
-
DOI 10.1191/0961203306lu2266oa
-
Quartuccio, L.; Sacco, S.; Franzolini, N.; Perin, A.; Ferraccioli, G.; De Vita, S. Efficacy of cyclosporin-A in the long-term management of thrombocytopenia associated with systemic lupus erythematosus. Lupus, 2006;15:76-79. (Pubitemid 43345331)
-
(2006)
Lupus
, vol.15
, Issue.2
, pp. 76-79
-
-
Quartuccio, L.1
Sacco, S.2
Franzolini, N.3
Perin, A.4
Ferraccioli, G.5
De Vita, S.6
-
21
-
-
0028025271
-
Cyclosporine treatment of lupus membranous nephropathy
-
Radhakrishnan, J.; Kunis, C.; D'Agat,i V.; Appel, G.B. Cyclosporine treatment of lupus membranous nephropathy. Clin. Nephrol., 1994, 42,147-154. (Pubitemid 24287748)
-
(1994)
Clinical Nephrology
, vol.42
, Issue.3
, pp. 147-154
-
-
Radhakrishnan, J.1
Kunisi, C.L.2
D'Agati, V.3
Appel, G.B.4
-
22
-
-
0030004197
-
Cyclosporin A in the treatment of systemic lupus erythematosus: Results of an open clinical study
-
Manger, K.; Kalden ,J.R.; Manger, B. Cyclosporin A in the treatment of systemic lupus erythematosus: Results of an open clinical study. Br. J. Rheumatol., 1996, 35, 669-675.
-
(1996)
Br. J. Rheumatol.
, vol.35
, pp. 669-675
-
-
Manger, K.1
Kalden, J.R.2
Manger, B.3
-
23
-
-
76049111620
-
Efficacy and safety of cyclosporine A in patients with refractory systemic lupus erythematosus in a daily clinical practice
-
Ogawa, H.; Kameda, H.; Amano, K.; Takeuchi, T. Efficacy and safety of cyclosporine A in patients with refractory systemic lupus erythematosus in a daily clinical practice. Lupus, 2010, 19,162-169.
-
(2010)
Lupus
, vol.19
, pp. 162-169
-
-
Ogawa, H.1
Kameda, H.2
Amano, K.3
Takeuchi, T.4
-
24
-
-
77955730184
-
The BILAG multi-centre open randomized controlled trial comparing ciclosporin vs azathioprine in patients with severe SLE
-
Griffiths, B.; Emery, P.; Ryan, V.; Isenberg, D.; Akil, M.; Thompson, R.; Maddison, P.; Griffiths, I.D.; Lorenzi, A.; Miles, S.; Situnayake, D.; The, L.S.; Plant, M.; Hallengren, C.; Nived, O.; Sturfelt, G.; Chakravarty, K.; Tait, T.; Gordon, C. The BILAG multi-centre open randomized controlled trial comparing ciclosporin vs azathioprine in patients with severe SLE. Rheumatology, 2010, 49,723-732.
-
(2010)
Rheumatology
, vol.49
, pp. 723-732
-
-
Griffiths, B.1
Emery, P.2
Ryan, V.3
Isenberg, D.4
Akil, M.5
Thompson, R.6
Maddison, P.7
Griffiths, I.D.8
Lorenzi, A.9
Miles, S.10
Situnayake, D.11
The, L.S.12
Plant, M.13
Hallengren, C.14
Nived, O.15
Sturfelt, G.16
Chakravarty, K.17
Tait, T.18
Gordon, C.19
-
25
-
-
0037247281
-
Newer drugs for the treatment of lupus nephritis
-
DOI 10.2165/00003495-200363020-00004
-
Kuiper-Geertsma, D.G.; Derksen, R.H. Newer drugs for the treatment of lupus nephritis. Drugs, 2003, 63, 167-180. (Pubitemid 36143343)
-
(2003)
Drugs
, vol.63
, Issue.2
, pp. 167-180
-
-
Kuiper-Geertsma, D.G.1
Derksen, R.H.W.M.2
-
26
-
-
77955358015
-
Efficacy and cytokine modulating effects of tacrolimus in systemic lupus erythematosus: A review
-
Yoon, K.H. Efficacy and cytokine modulating effects of tacrolimus in systemic lupus erythematosus: A review. J. Biomed. Biotechnol., 2010,686480.
-
(2010)
J. Biomed. Biotechnol.
, pp. 686480
-
-
Yoon, K.H.1
-
27
-
-
36348953163
-
Effective treatment of young patients with pediatric-onset, long-standing lupus nephritis with tacrolimus given as a single daily dose: An open-label pilot study
-
DOI 10.1177/0961203307081914
-
Tanaka, H.; Oki, E.; Tsugawa, K.; Nonaka, K.; Suzuki, K.; Ito, E. Effective treatment of young patients with pediatric-onset, long-standing lupus nephritis with tacrolimus given as a single daily dose: An open-label pilot study. Lupus, 2007,16,896-900 . (Pubitemid 350157276)
-
(2007)
Lupus
, vol.16
, Issue.11
, pp. 896-900
-
-
Tanaka, H.1
Oki, E.2
Tsugawa, K.3
Nonaka, K.4
Suzuki, K.5
Ito, E.6
-
28
-
-
0037247281
-
Newer drugs for the treatment of lupus nephritis
-
DOI 10.2165/00003495-200363020-00004
-
Kuiper-Geertsma, D.G.; Derksen, R.H. Newer drugs for the treatment of lupus nephritis. Drugs, 2003, 63, 167-180. (Pubitemid 36143343)
-
(2003)
Drugs
, vol.63
, Issue.2
, pp. 167-180
-
-
Kuiper-Geertsma, D.G.1
Derksen, R.H.W.M.2
-
29
-
-
72949113433
-
Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help
-
Heidt, S.; Roelen, D.L.; Eijsink, C.; Eikmans, M.; van Kooten, C.; Claas, F.H.; Mulder, A. Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help. J. Transl. Immunol., 2009, 159, 199-207.
-
(2009)
J. Transl. Immunol.
, vol.159
, pp. 199-207
-
-
Heidt, S.1
Roelen, D.L.2
Eijsink, C.3
Eikmans, M.4
Van Kooten, C.5
Claas, F.H.6
Mulder, A.7
-
30
-
-
0024541827
-
Effect of FK-506, a novel immunosuppressive drug on murine systemic lupus erythematosus
-
DOI 10.1016/0090-1229(89)90211-0
-
Takabayashi, K.; Koike, T.; Kurasawa, K.; Matsumura R, Sato, T.; Tomioka, H.; Ito, I.; Yoshiki, T.; Yoshida, S. Effect of FK-506, a novel immunosuppressive drug on murine systemic lupus erythematosus, Clin. Immunol. Immunopathol., 1989, 51,110-117. (Pubitemid 19096341)
-
(1989)
Clinical Immunology and Immunopathology
, vol.51
, Issue.1
, pp. 110-117
-
-
Takabayashi, K.1
Koike, T.2
Kurasawa, K.3
Matsumura, R.4
Sato, T.5
Tomioka, H.6
Ito, I.7
Yoshiki, T.8
Yoshida, S.9
-
31
-
-
0027319099
-
Effect of a novel immunosuppressant, FK506, on spontaneous lupus nephritis in MRL/MpJ-lpr/lpr mice
-
Entani, C.; Izumino, Y.; Iida, H.; Fujita, M.; Asaka, M.; Takata, M.; Sasayama, S. Effect of a novel immunosuppressant, FK506, on spontaneous lupus nephritis in MRL/MpJ-pr/lpr mice. Nephron, 1993,64, 471-475. (Pubitemid 23202862)
-
(1993)
Nephron
, vol.64
, Issue.3
, pp. 471-475
-
-
Entani, C.1
Izumino, Y.2
Iida, H.3
Fujita, M.4
Asaka, M.5
Takata, M.6
Sasayama, S.7
-
32
-
-
0031468757
-
Treatment of severe and difficult cases of systemic lupus erythematosus with tacrolimus. A report of three cases
-
Duddridge, M.; Powel,l R.J. Treatment of severe and difficult cases of systemic lupus erythematosus with tacrolimus. A report of three cases. Ann. Rheum. Dis., 1997, 56, 690-692. (Pubitemid 28007929)
-
(1997)
Annals of the Rheumatic Diseases
, vol.56
, Issue.11
, pp. 690-692
-
-
Duddridge, M.1
Powell, R.J.2
-
33
-
-
79951956544
-
Successful management of systemic lupus erythematosus nephritis flare-up during pregnancy with tacrolimus
-
Alsuwaida, A. Successful management of systemic lupus erythematosus nephritis flare-up during pregnancy with tacrolimus. Mod Rheumatol., 2011, 21,73-75.
-
(2011)
Mod Rheumatol.
, vol.21
, pp. 73-75
-
-
Alsuwaida, A.1
-
34
-
-
3343023890
-
Tacrolimus- (FK 506) based immunosupression in severe systemic lupus erythematosus
-
Politt, D.; Heintz, B.; Floege, J.; Mertens, P.R. Tacrolimus (FK-506) based immunosuppression in severe systemic lupus erythematosus. Clin. Nephrol., 2004; 62: 49-53. (Pubitemid 38986903)
-
(2004)
Clinical Nephrology
, vol.62
, Issue.1
, pp. 49-53
-
-
Politt, D.1
Heintz, B.2
Floege, J.3
Mertens, P.R.4
-
35
-
-
77956628766
-
Improvement of rapidly progressive lupus nephritis associated MPO-ANCA with tacrolimus
-
Morimoto S, Watanabe T, Lee S, Amano H, Kanamaru Y, Ohsawa I, Tomino Y, Takasaki Y. Improvement of rapidly progressive lupus nephritis associated MPO-ANCA with tacrolimus. Mod Rheumatol. 2010;20:291-294.
-
(2010)
Mod Rheumatol.
, vol.20
, pp. 291-294
-
-
Morimoto, S.1
Watanabe, T.2
Lee, S.3
Amano, H.4
Kanamaru, Y.5
Ohsawa, I.6
Tomino, Y.7
Takasaki, Y.8
-
36
-
-
26944455632
-
Tacrolimus for induction therapy of diffuse proliferative lupus nephritis: An open-labeled pilot study
-
DOI 10.1111/j.1523-1755.2005.00461.x, PII 4494653
-
Mok, C.C.;Tong, K.H.; To, Ch.; Siu, Y.P. Tacrolimus for induction therapy of diffuse proliferative lupus nephritis: An open- labeled pilot study. Kidney Int., 2005, 68, 813-817. (Pubitemid 43323138)
-
(2005)
Kidney International
, vol.68
, Issue.2
, pp. 813-817
-
-
Mok, C.C.1
Tong, K.H.2
To, C.H.3
Siu, Y.P.4
Au, T.C.5
-
37
-
-
69549095650
-
Clinical assessment of tacrolimus therapy in lupus nephritis: One-year follow-up study in a single center
-
Asamiya Y, Uchida K, Otsubo S, Takei T, Nitta K. ., Clinical assessment of tacrolimus therapy in lupus nephritis: One-year follow-up study in a single center, Nephron Clin. Pract., 2009, 113, 330-336.
-
(2009)
Nephron Clin. Pract.
, vol.113
, pp. 330-336
-
-
Asamiya, Y.1
Uchida, K.2
Otsubo, S.3
Takei, T.4
Nitta, K.5
-
38
-
-
73349090238
-
Efficacy and safety of tacrolimus for lupus nephritis: A placebo-controlled double-blind multicenter study
-
Nobuyuki, M.; Shinichi, K.; Hiroshi, H. Efficacy and safety of tacrolimus for lupus nephritis: A placebo-controlled double-blind multicenter study,Modern Rheumatology, 2009, 19, 606-615.
-
(2009)
Modern Rheumatology
, vol.19
, pp. 606-615
-
-
Nobuyuki, M.1
Shinichi, K.2
Hiroshi, H.3
-
39
-
-
54449092859
-
Tacrolimus for the treatment of systemic lupus erythematosus with pure class V nephritis
-
Szeto, C.C.; Kwan, B.C.; Lai, F.M.; Tam, L.S.; Li, E.K.; Chow, K.M.; Gang, W.; Li, P.K. Tacrolimus for the treatment of systemic lupus erythematosus with pure class V nephritis. Rheumatology, 2008, 47,1678-1681.
-
(2008)
Rheumatology
, vol.47
, pp. 1678-1681
-
-
Szeto, C.C.1
Kwan, B.C.2
Lai, F.M.3
Tam, L.S.4
Li, E.K.5
Chow, K.M.6
Gang, W.7
Li, P.K.8
-
40
-
-
79951956544
-
Successful management of systemic lupus erythematosus nephritis flare-up during pregnancy with tacrolimus
-
Alsuwaida, A.; Successful management of systemic lupus erythematosus nephritis flare-up during pregnancy with tacrolimus. Mod. Rheumatol. 2011, 21,73-75.
-
(2011)
Mod. Rheumatol.
, vol.21
, pp. 73-75
-
-
Alsuwaida, A.1
-
41
-
-
79959999365
-
Single center prospective study of tacrolimus efficacy and safety in the treatment of various manifestations in systemic lupus erythematosus
-
Suzuki, K.; Kameda, H.; Amano, K.; Nagasawa, H.; Takei, H.; Nishi, E.; Okuyama, A.; Tsuzaka, K.; Takeuchi, T. Single center prospective study of tacrolimus efficacy and safety in the treatment of various manifestations in systemic lupus erythematosus. Rheumatol. Int., 2011,31,757-63.
-
(2011)
Rheumatol. Int.
, vol.31
, pp. 757-763
-
-
Suzuki, K.1
Kameda, H.2
Amano, K.3
Nagasawa, H.4
Takei, H.5
Nishi, E.6
Okuyama, A.7
Tsuzaka, K.8
Takeuchi, T.9
-
42
-
-
73349086209
-
Tacrolimus therapy for systemic lupus erythematosus without renal involvement: A preliminary retrospective study
-
Kusunoki, Y.; Tanaka, N.; Kaneko, K.; Yamamoto, T.; Endo, H.; Kawai, S. Tacrolimus therapy for systemic lupus erythematosus without renal involvement: A preliminary retrospective study. Mod. Rheumatol., 2009,19, 616-21.
-
(2009)
Mod. Rheumatol.
, vol.19
, pp. 616-621
-
-
Kusunoki, Y.1
Tanaka, N.2
Kaneko, K.3
Yamamoto, T.4
Endo, H.5
Kawai, S.6
-
43
-
-
0037328684
-
Efficacy of topical tacrolimus for treating the malar rash of systemic lupus erythematosus
-
DOI 10.1046/j.1365-2133.2003.05186.x
-
Kanekura, T.; Yoshii, N.; Terasaki, K.; Miyoshi, H.; Kanzaki, T. Efficacy of topical tacrolimus for treating the malar rash of systemic lupus erythematosus. Br. J. Dermatol., 2003, 148, 353-356. (Pubitemid 36278982)
-
(2003)
British Journal of Dermatology
, vol.148
, Issue.2
, pp. 353-356
-
-
Kanekura, T.1
Yoshii, N.2
Terasaki, K.3
Miyoshi, H.4
Kanzaki, T.5
-
45
-
-
0032704059
-
Mycophenolate mofetil for the treatment of systemic lupus erythematosus: An open pilot trial
-
Gaubitz, M.; Schorat, A.; Schotte, H.; Kern, P.; Domschke, W. Mycophenolate mofetil for the treatment of systemic lupus erythematosus: An open pilot trial. Lupus, 1999, 8, 731-736.
-
(1999)
Lupus
, vol.8
, pp. 731-736
-
-
Gaubitz, M.1
Schorat, A.2
Schotte, H.3
Kern, P.4
Domschke, W.5
-
46
-
-
0034788417
-
The safety and efficacy of MMF in lupus nephritis: A pilot study
-
DOI 10.1191/096120301682430186
-
Kingdon, E.J.; McLean, A.G.; Psimenou, E.; Davenport, A.; Powis, S.H.; Sweny, P.; Burns, A. The safety and efficacy of MMF in lupus nephritis: A pilot study. Lupus, 2001, 10, 606-611. (Pubitemid 32959274)
-
(2001)
Lupus
, vol.10
, Issue.9
, pp. 606-611
-
-
Kingdon, E.J.1
McLean, A.G.2
Psimenou, E.3
Davenport, A.4
Powis, S.H.5
Sweny, P.6
Burns, A.7
-
47
-
-
0036051895
-
Mycophenolate mofetil for systemic lupus erythematosus refractory to other immunosuppressive agents
-
Karim, M.Y.; Alba, P.; Cuadrado, M.J.; Abbs, I.C.; D'Cruz, D.P.; Khamashta, M.A, Hughes, G.R. Mycophenolate mofetil for systemic lupus erythematosus refractory to other immunosuppressive agents. Rheumatol., 2002, 41, 876-882.
-
(2002)
Rheumatol.
, vol.41
, pp. 876-882
-
-
Karim, M.Y.1
Alba, P.2
Cuadrado, M.J.3
Abbs, I.C.4
D'Cruz, D.P.5
Khamashta, M.A.6
Hughes, G.R.7
-
48
-
-
17344373954
-
Successful mycophenolate mofetil treatment of glomerular disease
-
Briggs, W.A.; Choi, M.J.; Scheel, P.J. Jr. Successful mycophenolate mofetil treatment of glomerular disease. Am. J. Kidney Dis., 1998, 31, 213-217.
-
(1998)
Am. J. Kidney Dis.
, vol.31
, pp. 213-217
-
-
Briggs, W.A.1
Choi, M.J.2
Scheel Jr., P.J.3
-
49
-
-
0031880581
-
Mycophenolate mofetil therapy for lupus nephritis refractory to intravenous cyclophosphamide
-
Glicklich, D.; Acharya, A. Mycophenolate mofetil therapy for lupus nephritis refractory to intravenous cyclophosphamide. Am. J. Kidney Dis., 1998,32, 318-322.
-
(1998)
Am. J. Kidney Dis.
, vol.32
, pp. 318-322
-
-
Glicklich, D.1
Acharya, A.2
-
50
-
-
0032986483
-
Mycophenolate mofetil therapy in lupus nephritis: Clinical observations
-
Dooley, M.A., Cosio, F.G., Nachman, P.H.; Falkenhain, M.E.; Hogan, S.L.; Falk, R.J.; Hebert, L.A. Mycophenolate mofetil therapy in lupus nephritis clinical observations. J. Am. Soc. Nephrol., 1999, 10, 833-839. (Pubitemid 29149534)
-
(1999)
Journal of the American Society of Nephrology
, vol.10
, Issue.4
, pp. 833-839
-
-
Dooley, M.A.1
Cosio, F.G.2
Nachman, P.H.3
Falkenhain, M.E.4
Hogan, S.L.5
Falk, R.J.6
Hebert, L.A.7
-
51
-
-
79955645934
-
Pharmacokinetic variability of mycophenolic acid and its glucuronide in systemic lupus erythematosus patients in remission maintenance phase
-
Mino, Y.; Naito, T.; Shimoyama, K.; Ogawa, N.; Kawakami, J. Pharmacokinetic variability of mycophenolic acid and its glucuronide in systemic lupus erythematosus patients in remission maintenance phase. Biol. Pharm. Bull. 2011, 34,755-759.
-
(2011)
Biol. Pharm. Bull.
, vol.34
, pp. 755-759
-
-
Mino, Y.1
Naito, T.2
Shimoyama, K.3
Ogawa, N.4
Kawakami, J.5
-
52
-
-
28144433147
-
Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis
-
Ginzler, E.M.; Dooley, M.A.; Aranow, C.; Kim, M.Y.; Buyon, J.; Merrill, J.T.; Petri, M.; Gilkeson, G.S.; Wallace, D.J.; Weisman, M.H.; Appel, G.B. Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis. N. Engl. J. Med., 2005, 353, 2219-222.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 2219-2222
-
-
Ginzler, E.M.1
Dooley, M.A.2
Aranow, C.3
Kim, M.Y.4
Buyon, J.5
Merrill, J.T.6
Petri, M.7
Gilkeson, G.S.8
Wallace, D.J.9
Weisman, M.H.10
Appel, G.B.11
-
53
-
-
1442355581
-
Sequential therapies for proliferative lupus nephritis
-
DOI 10.1056/NEJMoa031855
-
Contreras, G.; Pardo, V.; Leclercq, B.; Lenz, O.; Tozman, E.; O'Nan, P.; Roth, D. Sequential therapies for proliferative lupus nephritis. N. Engl. J. Med., 2004, 350, 971-980. (Pubitemid 38269274)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.10
, pp. 971-980
-
-
Contreras, G.1
Pardo, V.2
Leclercq, B.3
Lenz, O.4
Tozman, E.5
O'Nan, P.6
Roth, D.7
-
54
-
-
0034941002
-
Treatment of resistant discoid lupus erythematosus of the palms and soles with mycophenolate mofetil
-
DOI 10.1067/mjd.2001.114297
-
Goyal, S.; Nousari, H.C. Treatment of resistant discoid lupus erythematosus of the palms and soles with mycophenolate mofetil. J. Am. Acad. Dermatol., 2001, 45, 142-144. (Pubitemid 32655712)
-
(2001)
Journal of the American Academy of Dermatology
, vol.45
, Issue.1
, pp. 142-144
-
-
Goyal, S.1
Nousari, H.C.2
-
55
-
-
0036898416
-
Mycophenolate mofetil for the treatment of cutaneous lupus erythematosus with smoldering systemic involvement
-
Hanjani, N.M.; Nousari, C.H. Mycophenolate mofetil for the treatment of cutaneous lupus erythematosus with smoldering systemic involvement. Arch. Dermatol., 2002, 138, 1616-1618. (Pubitemid 35453486)
-
(2002)
Archives of Dermatology
, vol.138
, Issue.12
, pp. 1616-1618
-
-
Michelle Hanjani, N.1
Nousari, C.H.2
-
56
-
-
0036068205
-
Successful treatment of subacute cutaneous lupus erythematosus with mycophenolate mofetil
-
DOI 10.1046/j.1365-2133.2002.04875.x
-
Schanz, S.; Ulmer, A.; Rassner, G.; Fierlbeck, G. Successful treatment of subacute cutaneous lupus erythematosus with mycophenolate mofetil. Br. J. Dermatol., 2002, 147, 174-178. (Pubitemid 34779458)
-
(2002)
British Journal of Dermatology
, vol.147
, Issue.1
, pp. 174-178
-
-
Schanz, S.1
Ulmer, A.2
Rassner, G.3
Fierlbeck, G.4
-
57
-
-
0041464661
-
Refractory immune thrombocytopenia in systemic lupus erythematosus: Response to mycophenolate mofetil
-
DOI 10.1191/0961203303lu417cr
-
Vasoo, S.; Thumboo, J.; Fong, K.Y. Refractory immune thrombocytopenia in systemic lupus erythematosus: Response to mycophenolate mofetil. Lupus, 2003, 12, 630-632. (Pubitemid 37021800)
-
(2003)
Lupus
, vol.12
, Issue.8
, pp. 630-632
-
-
Vasoo, S.1
Thumboo, J.2
Fong, K.-Y.3
-
58
-
-
0042466330
-
Mycophenolate mofetil as a treatment for autoimmune haemolytic anaemia in patients with systemic lupus erythematosus and antiphospholipid syndrome
-
DOI 10.1191/0961203303lu419cr
-
Alba, P.; Karim, M.Y.; Hunt, B.J. Mycophenolate mofetil as a treatment for autoimmune haemolytic anaemia in patients with systemic lupus erythematosus and antiphospholipid syndrome. Lupus, 2003, 12, 633-635. (Pubitemid 37021801)
-
(2003)
Lupus
, vol.12
, Issue.8
, pp. 633-635
-
-
Alba, P.1
Karim, M.Y.2
Hunt, B.J.3
-
59
-
-
0141719789
-
Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil
-
DOI 10.1097/01.SMJ.0000054424.20202.7D
-
Samad, A.S.; Lindsley, C.B. Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil. South. Med. J., 2003,96, 705-707. (Pubitemid 38292569)
-
(2003)
Southern Medical Journal
, vol.96
, Issue.7
, pp. 705-707
-
-
Samad, A.S.1
Lindsley, C.B.2
-
60
-
-
0037829132
-
Tolerability of mycophenolate mofetil in patients with systemic lupus erythematosus
-
Riskalla, M.M.; Somers, E.C.; Fatica, R.A.; McCune, W.J. Tolerability of mycophenolate mofetil in patients with systemic lupus erythematosus. J. Rheumatol., 2003, 30, 1508-1512. (Pubitemid 36835447)
-
(2003)
Journal of Rheumatology
, vol.30
, Issue.7
, pp. 1508-1512
-
-
Riskalla, M.M.1
Somers, E.C.2
Fatica, R.A.3
McCune, W.J.4
-
62
-
-
70350418625
-
MTOR signaling at a glance
-
Laplante, M.; Sabatini, D.M. mTOR signaling at a glance. J. Cell Sci. 2009,122,3589-94.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3589-3594
-
-
Laplante, M.1
Sabatini, D.M.2
-
63
-
-
77953720799
-
MTOR signaling: A central pathway to pathogenesis in systemic lupus erythematosus?
-
Fernandez, D.; Perl, A. mTOR signaling: A central pathway to pathogenesis in systemic lupus erythematosus? Discov. Med., 2010,9,173-8.
-
(2010)
Discov. Med.
, vol.9
, pp. 173-178
-
-
Fernandez, D.1
Perl, A.2
-
64
-
-
33846396190
-
Aspects of mTOR biology and the use of mTOR inhibitors in non-Hodgkin's lymphoma
-
DOI 10.1016/j.ctrv.2006.10.004, PII S0305737206002052
-
Costa, L.J. Aspects of mTOR biology and the use of mTOR inhibitors in non-Hodgkin's lymphoma. Cancer Treat Rev., 2007,33,78-84. (Pubitemid 46132007)
-
(2007)
Cancer Treatment Reviews
, vol.33
, Issue.1
, pp. 78-84
-
-
Costa, L.J.1
-
65
-
-
33750242457
-
Investigating mammalian target of rapamycin inhibitors for their anticancer properties
-
DOI 10.1517/13543784.15.10.1201
-
Smolewski, P. Investigating mammalian target of rapamycin inhibitors for their anticancer properties. Expert Opin. Investig. Drugs, 2006,15, 1201-1227. (Pubitemid 44608260)
-
(2006)
Expert Opinion on Investigational Drugs
, vol.15
, Issue.10
, pp. 1201-1227
-
-
Smolewski, P.1
-
66
-
-
27644447574
-
The mammalian target of the rapamycin (mTOR) kinase pathway: Its role in tumourigenesis and targeted antitumour therapy
-
Janus, A.; Robak, T.; Smolewski, P. The mammalian target of the rapamycin (mTOR) kinase pathway: Its role in tumourigenesis and targeted antitumour therapy. Cell. Mol. Biol. Lett., 2005, 10, 479-498. (Pubitemid 41564520)
-
(2005)
Cellular and Molecular Biology Letters
, vol.10
, Issue.3
, pp. 479-498
-
-
Janus, A.1
Robak, T.2
Smolewski, P.3
-
67
-
-
8344281974
-
Targeting the molecular target of rapamycin (mTOR)
-
DOI 10.1097/01.cco.0000143964.74936.d1
-
Rowinsky, E.K. Targeting the molecular target of rapamycin (mTOR). Curr. Opin. Oncol., 2004,16,564-75. (Pubitemid 39482975)
-
(2004)
Current Opinion in Oncology
, vol.16
, Issue.6
, pp. 564-575
-
-
Rowinsky, E.K.1
-
68
-
-
33748194240
-
Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway
-
PII 0000181320060600000001
-
Smolewski, P. Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway. Anticancer Drugs, 2006, 17, 487-94. (Pubitemid 44309964)
-
(2006)
Anti-Cancer Drugs
, vol.17
, Issue.5
, pp. 487-494
-
-
Smolewski, P.1
-
69
-
-
67650074206
-
MTOR regulates memory CD8 Tcell differentiation
-
Araki, K, Turner, A.P.; Shaffer, V.O.; Gangappa, S.; Keller, S.A.; Bachmann, M.F.; Larsen, C.P.; Ahmed, R. mTOR regulates memory CD8 Tcell differentiation. Nature, 2009 ,460,108-12.
-
(2009)
Nature
, vol.460
, pp. 108-112
-
-
Araki, K.1
Turner, A.P.2
Shaffer, V.O.3
Gangappa, S.4
Keller, S.A.5
Bachmann, M.F.6
Larsen, C.P.7
Ahmed, R.8
-
70
-
-
77953720799
-
MTOR signaling: A central pathway to pathogenesis in systemic lupus erythematosus?
-
Fernandez, D.; Perl, A. mTOR signaling: A central pathway to pathogenesis in systemic lupus erythematosus? Discov. Med., 2010, 9,173-8.
-
(2010)
Discov. Med.
, vol.9
, pp. 173-178
-
-
Fernandez, D.1
Perl, A.2
-
71
-
-
0028107540
-
Rapamycin prolongs survival and arrests pathophysiologic changes in murine systemic lupus erythematosus
-
Warner, L.M.; Adams, L.M.; Sehgal, S.N. Rapamycin prolongs survival and arrests pathophysiologic changes in murine systemic lupus erythematosus. Arthritis Rheum., 1994,37,289-297. (Pubitemid 24065505)
-
(1994)
Arthritis and Rheumatism
, vol.37
, Issue.2
, pp. 289-297
-
-
Warner, L.M.1
Adams, L.M.2
Sehgal, S.N.3
-
72
-
-
0036228268
-
Abetimus (La Jolla pharmaceuticals)
-
Lorenz, H.M. Abetimus (La Jolla pharmaceuticals). Curr. Opin. Investig. Drugs, 2002, 3, 234-239.
-
(2002)
Curr. Opin. Investig. Drugs
, vol.3
, pp. 234-239
-
-
Lorenz, H.M.1
-
73
-
-
0028501008
-
Conjugates of double-stranded oligonucleotides with poly(ethylene glycol) and keyhole limpet hemocyanin: A model for treating systemic lupus erythematosus
-
Jones, D.S.; Hachmann, J.P.; Osgood, S.A.; Hayag, M.S.; Barstad, P.A.; Iverson, G.M.; Coutts, S.M. Conjugates of double-stranded oligonucleotides with poly(ethylene glycol) and keyhole limpet hemocyanin: A model for treating systemic lupus erythematosus. Bioconjug Chem., 1994,5,390-399. (Pubitemid 2144394)
-
(1994)
Bioconjugate Chemistry
, vol.5
, Issue.5
, pp. 390-399
-
-
Jones, D.S.1
Hachmann, J.P.2
Osgood, S.A.3
Hayag, M.S.4
Barstad, P.A.5
Iverson, G.M.6
Coutts, S.M.7
-
74
-
-
49449093009
-
LJP 394-90-09 Investigator Consortium. Abetimus sodium for renal flare in systemic lupus erythematosus: Results of a randomized, controlled phase III trial
-
Cardiel, M.H.; Tumlin, J.A.; Furie, R.A.; Wallace, D.J.; Joh, T.; Linnik, M.D.; LJP 394-90-09 Investigator Consortium. Abetimus sodium for renal flare in systemic lupus erythematosus: Results of a randomized, controlled phase III trial. Arthritis Rheum., 2008,58, 2470-2480.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 2470-2480
-
-
Cardiel, M.H.1
Tumlin, J.A.2
Furie, R.A.3
Wallace, D.J.4
Joh, T.5
Linnik, M.D.6
-
75
-
-
53049100124
-
Pharmacokinetics of high-dose abetimus sodium in normal subjects with specific assessment of effect on coagulation
-
DOI 10.1177/0091270008319465
-
Linnik, M.D.; O'Rourke, A.M.; Crowther, M.A. Pharmacokinetics of highdose abetimus sodium in normal subjects with specific assessment of effect on coagulation. J. Clin. Pharmacol., 2008,48, 909-918. (Pubitemid 352009490)
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.8
, pp. 909-918
-
-
Linnik, M.D.1
O'Rourke, A.M.2
Crowther, M.A.3
-
76
-
-
0028286363
-
Conjugates or dsDNA linked to human gammaglobulin inhibit anti-dsDNA antibodies in vitro
-
Mikael, N.; Boguniewicz, M.; Manakata, Y.; Sasaki, T.; Borel, H.; Borel, Y. Conjugates or dsDNA linked to human gammaglobulin inhibit anti-dsDNA antibodies in vitro. Lupus, 1994, 3,173-179. (Pubitemid 24229885)
-
(1994)
Lupus
, vol.3
, Issue.3
, pp. 173-179
-
-
Mikael, N.1
Boguniewicz, M.2
Manakata, Y.3
Sasaki, T.4
Borel, H.5
Borel, Y.6
-
77
-
-
0029995138
-
Pharmacological intervention in antibody mediated disease
-
Coutts, S.M.; Plunkett, M.L.; Iverson, G.M.; Barstad, P.A.; Berner, C.M. Pharmacological intervention in antibody mediated disease. Lupus, 1996,5,158-159. (Pubitemid 26135163)
-
(1996)
Lupus
, vol.5
, Issue.2
, pp. 158-159
-
-
Coutts, S.M.1
Plunkett, M.L.2
Iverson, G.M.3
Barstad, P.A.4
Berner, C.M.5
-
78
-
-
0036228268
-
Abetimus (La Jolla Pharmaceuticals)
-
Lorenz, H.M., Abetimus (La Jolla Pharmaceuticals). Curr. Opin. Investig. Drugs, 2002, 3, 234-239.
-
(2002)
Curr. Opin. Investig. Drugs
, vol.3
, pp. 234-239
-
-
Lorenz, H.M.1
-
79
-
-
67650682701
-
Abetimus sodium: A medication for the prevention of lupus nephritis flares
-
Horowitz, D.M.; Furie, R.A. Abetimus sodium: A medication for the prevention of lupus nephritis flares. Expert. Opin. Pharmacother., 2009,10,1501-1507.
-
(2009)
Expert. Opin. Pharmacother.
, vol.10
, pp. 1501-1507
-
-
Horowitz, D.M.1
Furie, R.A.2
-
80
-
-
12744275048
-
Abetimus sodium: A new therapy for delaying the time to, and reducing the incidence of renal flare and/or major systemic lupus erythematosus flares in patients with systemic lupus erythematosus who have a history of renal disease
-
Cardiel, M.H. Abetimus sodium: A new therapy for delaying the time to, and reducing the incidence of renal flare and/or major systemic lupus erythematosus flares in patients with systemic lupus erythematosus who have a history of renal disease. Expert. Opin. Investig. Drugs, 2005,14, 77-88.
-
(2005)
Expert. Opin. Investig. Drugs
, vol.14
, pp. 77-88
-
-
Cardiel, M.H.1
-
81
-
-
0141849087
-
Improvement in health-related quality of life in systemic lupus erythematosus patients enrolled in a randomized clinical trial comparing LJP 394 treatment with placebo
-
Strand, V.; Aranow, C.; Cardie,l M.H.; Alarcón-Segovia, D.; Furie, R.; Sherrer, Y.; Tumlin, J.; Wallace, D.J.; Crawford, B.; LJP 394 Investigator Consortium. Improvement in health-related quality of life in systemic lupus erythematosus patients enrolled in a randomized clinical trial comparing LJP 394 treatment with placebo. Lupus, 2003,12,677-686. (Pubitemid 37173664)
-
(2003)
Lupus
, vol.12
, Issue.9
, pp. 677-686
-
-
Strand, V.1
Aranow, C.2
Cardiel, M.H.3
Alarcon-Segovia, D.4
Furie, R.5
Sherrer, Y.6
Tumlin, J.7
Wallace, D.J.8
Crawford, B.9
-
82
-
-
49449093009
-
LJP 394-90-09 Investigator Consortium. Abetimus sodium for renal flare in systemic lupus erythematosus: Results of a randomized, controlled phase III trial
-
Cardie,l M.H.; Tumlin, J.A.; Furie, R.A.; Wallace, D.J.; Joh, T.; Linnik, M.D. LJP 394-90-09 Investigator Consortium. Abetimus sodium for renal flare in systemic lupus erythematosus: Results of a randomized, controlled phase III trial. Arthritis Rheum., 2008,58,2470-2480.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 2470-2480
-
-
Cardiel, M.H.1
Tumlin, J.A.2
Furie, R.A.3
Wallace, D.J.4
Joh, T.5
Linnik, M.D.6
-
83
-
-
0038621321
-
Abetimus: Abetimus sodium, LJP 394
-
Abetimus: Abetimus sodium, LJP 394. BioDrugs., 2003,17,212-215.
-
(2003)
BioDrugs.
, vol.17
, pp. 212-215
-
-
-
84
-
-
0029549896
-
Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline
-
DOI 10.1111/j.1749-6632.1995.tb17370.x
-
Hornsby, P.J. Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline. Ann. N. Y. Acad. Sci., 1995, 774, 29-46. (Pubitemid 26140358)
-
(1995)
Annals of the New York Academy of Sciences
, vol.774
, pp. 29-46
-
-
Hornsby, P.J.1
-
85
-
-
0023261410
-
Low plasma androgens in women with systemic lupus erythematosus
-
DOI 10.1002/art.1780300301
-
Lahita, R.G.; Bradlow, H.L.; Ginzler, E.; Pang, S.; New, M. Low plasma androgens in women with systemic lupus erythematosus. Arthritis Rheum., 1987, 30, 241-248. (Pubitemid 17098574)
-
(1987)
Arthritis and Rheumatism
, vol.30
, Issue.3
, pp. 241-248
-
-
Lahita, R.G.1
Bradlow, H.L.2
Ginzler, E.3
-
86
-
-
20244364828
-
Effects of prasterone on bone mineral density in women with systemic lupus erythematosus receiving chronic glucocorticoid therapy
-
Mease, P.J.; Ginzler, E.M.; Gluck, O.S.; Schiff, M.; Goldman, A.; Greenwald, M.; Cohen, S.; Egan, R.; Quarles, B.J.; Schwartz, K.E. Effects of prasterone on bone mineral density in women with systemic lupus erythematosus receiving chronic glucocorticoid therapy. J. Rheumatol., 2005,32, 616-621. (Pubitemid 40524691)
-
(2005)
Journal of Rheumatology
, vol.32
, Issue.4
, pp. 616-621
-
-
Mease, P.J.1
Ginzler, E.M.2
Gluck, O.S.3
Schiff, M.4
Goldman, A.5
Greenwald, M.6
Cohen, S.7
Egan, R.8
Quarles, B.J.9
Schwartz, K.E.10
-
88
-
-
0029622347
-
Dehydroepiandrosterone in systemic lupus erythematosus: Results of a double-blind, placebo-controlled, randomized clinical trial
-
DOI 10.1002/art.1780381216
-
Van Vollenhoven, R.F.; Engleman, E.G.; McGuire, J.L. Dehydroepiandrosterone in systemic lupus erythematosus: Results of a double-blind, placebo-controlled, randomized clinical trial. Arthritis Rheum., 1995,38,1826-1831. (Pubitemid 26010284)
-
(1995)
Arthritis and Rheumatism
, vol.38
, Issue.12
, pp. 1826-1831
-
-
Van Vollenhoven, R.F.1
Engleman, E.G.2
McGuire, J.L.3
-
89
-
-
4444300345
-
Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus
-
Petri, M.A.; Mease, P.J.; Merrill, J.T.; Lahita, R.G.; Iannini, M.J.; Yocum, D.E.; Ginzler, E.M.; Katz, R.S.; Gluck, O.S.; Genovese, M.C.; Van Vollenhoven, R.; Kalunian, K.C.; Manzi, S.; Greenwald, M.W.; Buyon, J.P., Olsen, N.J.; Schiff, M.H.; Kavanaugh, A.F.; Caldwell, J.R.; Ramsey- Goldman, R.; St Clair, E.W.; Goldman, A.L.; Egan, R.M.; Polisson, R.P.; Moder, K.G.; Rothfield, N.F.; Spencer, R.T.; Hobbs, K.; Fessler, B.J.; Calabrese, L.H.; Moreland, L.W.; Cohen, S.B.; Quarles, B.J.; Strand, V.; Gurwith, M.; Schwartz, K.E. Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus. Arthritis Rheum., 2004,50,2858-2868.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 2858-2868
-
-
Petri, M.A.1
Mease, P.J.2
Merrill, J.T.3
Lahita, R.G.4
Iannini, M.J.5
Yocum, D.E.6
Ginzler, E.M.7
Katz, R.S.8
Gluck, O.S.9
Genovese, M.C.10
Van Vollenhoven, R.11
Kalunian, K.C.12
Manzi, S.13
Greenwald, M.W.14
Buyon, J.P.15
Olsen, N.J.16
Schiff, M.H.17
Kavanaugh, A.F.18
Caldwell, J.R.19
Ramsey-Goldman, R.20
St Clair, E.W.21
Goldman, A.L.22
Egan, R.M.23
Polisson, R.P.24
Moder, K.G.25
Rothfield, N.F.26
Spencer, R.T.27
Hobbs, K.28
Fessler, B.J.29
Calabrese, L.H.30
Moreland, L.W.31
Cohen, S.B.32
Quarles, B.J.33
Strand, V.34
Gurwith, M.35
Schwartz, K.E.36
more..
-
90
-
-
0032858281
-
A small synthetic molecule capable of preferentially inhibiting the production of the CC chemokine monocyte chemotactic protein-1
-
Sironi, M.; Guglielmotti, A.; Polentarutti, N.; Fioretti, F.; Milanese, C.; Romano, M.; Vigini, C.; Coletta, I.; Sozzani, S.; Bernasconi, S.; Vecchi, A.; Pinza, M.; Mantovan,i A. A small synthetic molecule capable of preferentially inhibiting the production of the CC chemokine monocyte chemotactic protein-1. Eur. Cytokine Netw., 1999,10,437-442.
-
(1999)
Eur. Cytokine Netw.
, vol.10
, pp. 437-442
-
-
Sironi, M.1
Guglielmotti, A.2
Polentarutti, N.3
Fioretti, F.4
Milanese, C.5
Romano, M.6
Vigini, C.7
Coletta, I.8
Sozzani, S.9
Bernasconi, S.10
Vecchi, A.11
Pinza, M.12
Mantovani, A.13
-
91
-
-
58149390072
-
Impact of the anti-inflammatory agent bindarit on the chemokinome: Selective inhibition of the monocyte chemotactic proteins
-
Mirolo, M.; Fabbri, M.; Sironi, M.; Vecchi, A.; Guglielmotti, A.; Mangano, G.; Biondi, G.; Locati, M.; Mantovani, A. Impact of the anti-inflammatory agent bindarit on the chemokinome: Selective inhibition of the monocyte chemotactic proteins. Eur. Cytokine Netw., 2008,19,119-122.
-
(2008)
Eur. Cytokine Netw.
, vol.19
, pp. 119-122
-
-
Mirolo, M.1
Fabbri, M.2
Sironi, M.3
Vecchi, A.4
Guglielmotti, A.5
Mangano, G.6
Biondi, G.7
Locati, M.8
Mantovani, A.9
-
92
-
-
0035999583
-
Amelioration of rat adjuvant arthritis by therapeutic treatment with bindarit, an inhibitor of MCP-1 and TNF-α production
-
Guglielmotti, A.; D'Onofrio, E.; Coletta, I.; Aquilini, L.; Milanese, C.; Pinza, M.; Amelioration of rat adjuvant arthritis by therapeutic treatment with bindarit, an inhibitor of MCP-1 and TNF-alpha production. Inflamm Res, 2002,51,252-258. (Pubitemid 34526441)
-
(2002)
Inflammation Research
, vol.51
, Issue.5
, pp. 252-258
-
-
Guglielmotti, A.1
D'Onofrio, E.2
Coletta, I.3
Aquilini, L.4
Milanese, C.5
Pinza, M.6
-
93
-
-
0026469242
-
A new protein antidenaturant agent, bindarit, reduces secondary phase of adjuvant arthritis in rats
-
Cioli, V.; Ciarniello, M.G.; Guglielmotti, A.; Luparini, M.R.; Durando, L.; Martinelli, B.; Catanese, B.; Fava, L.; Silvestrini, B. A new protein antidenaturant agent, bindarit, reduces secondary phase of adjuvant arthritis in rats. J. Rheumatol.,1992,19,1735-1742.
-
(1992)
J. Rheumatol.
, vol.19
, pp. 1735-1742
-
-
Cioli, V.1
Ciarniello, M.G.2
Guglielmotti, A.3
Luparini, M.R.4
Durando, L.5
Martinelli, B.6
Catanese, B.7
Fava, L.8
Silvestrini, B.9
-
94
-
-
0027285022
-
Chronic inflammatory response in the rat can be blocked by bindarit
-
Guglielmotti, A.; Silvestrini, B.; Saso, L.; Zwain, I.; Cheng, C.Y. Chronic inflammatory response in the rat can be blocked by bindarit. Biochem. Mol. Biol. Int .,1993,29,747-756. (Pubitemid 23164767)
-
(1993)
Biochemistry and Molecular Biology International
, vol.29
, Issue.4
, pp. 747-756
-
-
Guglielmotti, A.1
Silvestrini, B.2
Saso, L.3
Zwain, I.4
Yan Cheng, C.5
-
95
-
-
0031778368
-
Bindarit prolongs survival and reduces renal damage in NZB/W lupus mice
-
Guglielmotti, A.; Aquilini, L.; D'Onofrio, E.; Rosignoli, M.T.; Milanese, C.; Pinza, M. Bindarit prolongs survival and reduces renal damage in NZB/W lupus mice. Clin. Exp. Rheumatol., 1998,16,149-154. (Pubitemid 28241568)
-
(1998)
Clinical and Experimental Rheumatology
, vol.16
, Issue.2
, pp. 149-154
-
-
Guglielmotti, A.1
Aquilini, L.2
D'Onofrio, E.3
Rosignoli, M.T.4
Milanese, C.5
Pinza, M.6
-
96
-
-
43149120462
-
Therapy Insight: Cardiovascular disease in pediatric systemic lupus erythematosus
-
DOI 10.1038/ncprheum0789, PII NCPRHEUM0789
-
Sandborg, C.; Ardoin, S.P.; Schanberg, L. Therapy Insight: Cardiovascular disease in pediatric systemic lupus erythematosus. Nat. Clin. Pract. Rheumatol., 2008 ,4,258-265. (Pubitemid 351638683)
-
(2008)
Nature Clinical Practice Rheumatology
, vol.4
, Issue.5
, pp. 258-265
-
-
Sandborg, C.1
Ardoin, S.P.2
Schanberg, L.3
-
97
-
-
0033529171
-
1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase
-
DOI 10.1073/pnas.96.14.7797
-
Rao, S.; Porter, D.C.; Chen, X.; Herliczek, T.; Lowe, M.; Keyomarsi, K. Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. Proc. Natl. Acad. Sci. USA., 1999,96,7797-7802. (Pubitemid 29328361)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.14
, pp. 7797-7802
-
-
Rao, S.1
Porter, D.C.2
Chen, X.3
Herliczek, T.4
Lowe, M.5
Keyomarsi, K.6
-
98
-
-
28844490054
-
Statins and cancer prevention
-
DOI 10.1038/nrc1751
-
Demierre, M.F.; Higgins, P.D.; Gruber, S.B.; Hawk, E.; Lippman, S.M. Statins and cancer prevention. Nat. Rev. Cancer., 2005,5,930-942. (Pubitemid 41766782)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.12
, pp. 930-942
-
-
Demierre, M.-F.1
Higgins, P.D.R.2
Gruber, S.B.3
Hawk, E.4
Lippman, S.M.5
-
99
-
-
0032572043
-
Antiatherothrombotic properties of statins: Implications for cardiovascular event reduction
-
DOI 10.1001/jama.279.20.1643
-
Rosenson, R.S.; Tangney, C.C. Antiatherothrombotic properties of statins: Implications for cardiovascular event reduction. JAMA,1998, 279,1643-1650. (Pubitemid 28248591)
-
(1998)
Journal of the American Medical Association
, vol.279
, Issue.20
, pp. 1643-1650
-
-
Rosenson, R.S.1
Tangney, C.C.2
-
100
-
-
36549044366
-
Statyny - Czy okaza̧ siȩ przydatne w reumatologii?
-
Bielinska, A.; Gluszko, P. Statins-are they potentially useful in rheumatology? Pol. Arch. Med. Wewn., 2007,117, 420-425. (Pubitemid 350190348)
-
(2007)
Polskie Archiwum Medycyny Wewnetrznej
, vol.117
, Issue.9
, pp. 420-425
-
-
Bielinska, A.1
Gluszko, P.2
-
101
-
-
10344253817
-
1 mice
-
Lawman, S.; Mauri, C.; Jury, E.C.; Cook, H.T.; Ehrenstein, M.R. Atorvastatin inhibits autoreactive B cell activation and delays lupus development in New Zealand black/white F1 mice. J. Immunol, 2004,173,7641-7646. (Pubitemid 39628206)
-
(2004)
Journal of Immunology
, vol.173
, Issue.12
, pp. 7641-7646
-
-
Lawman, S.1
Mauri, C.2
Jury, E.C.3
Cook, H.T.4
Ehrenstein, M.E.5
-
102
-
-
47249120828
-
Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus
-
DOI 10.1002/art.23605
-
Graham, K.L.; Lee, L.Y.; Higgins, J.P.; Steinman, L.; Utz, P.J.; Ho, P.P. Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus. Arthritis Rheum., 2008, 58,2098-2104. (Pubitemid 351988101)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.7
, pp. 2098-2104
-
-
Graham, K.L.1
Lee, L.Y.2
Higgins, J.P.3
Steinman, L.4
Utz, P.J.5
Ho, P.P.6
-
103
-
-
2142710163
-
Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus
-
DOI 10.1172/JCI200420345
-
Jury, E. C.; Kabouridis, P.S.; Flores-Borja, F.; Mageed, R.A.; Isenberg, D.A. Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus. J. Clin. Invest.,2004,113,1176-1187. (Pubitemid 38544103)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.8
, pp. 1176-1187
-
-
Jury, E.C.1
Kabouridis, P.S.2
Flores-Borja, F.3
Mageed, R.A.4
Isenberg, D.A.5
-
104
-
-
0041464676
-
Therapy with statins in patients with refractory rheumatic diseases: A preliminary study
-
DOI 10.1191/0961203303lu429oa
-
Abud-Mendoza, C.; de la Fuente, H.; Cuevas-Orta, E.; Baranda, L.; Cruz- Rizo, J.; González-Amaro, R.Therapy with statins in patients with refractory rheumatic diseases: A preliminary study. Lupus, 2003,12,607-611. (Pubitemid 37021796)
-
(2003)
Lupus
, vol.12
, Issue.8
, pp. 607-611
-
-
Abud-Mendoza, C.1
De La Fuente, H.2
Cuevas-Orta, E.3
Baranda, L.4
Cruz-Rizo, J.5
Gonzalez-Amaro, R.6
-
105
-
-
34848831197
-
Atorvastatin therapy improves endothelial-dependent vasodilation in patients with systemic lupus erythematosus: An 8 weeks controlled trial
-
DOI 10.1093/rheumatology/kem186
-
Ferreira, G.A.; Navarro, T.P.; Telles, R.W., Andrade, L.E.; Sato, E. Atorvastatin therapy improves endothelial-dependent vasodilation in patients with systemic lupus erythematosus: An 8 weeks controlled trial. Rheumatology (Oxford)., 2007,46, 1560-1565. (Pubitemid 47500570)
-
(2007)
Rheumatology
, vol.46
, Issue.10
, pp. 1560-1565
-
-
Ferreira, G.A.1
Navarro, T.P.2
Telles, R.W.3
Andrade, L.E.C.4
Sato, E.I.5
-
106
-
-
33750811623
-
Atorvastatin restores Lck expression and lipid raft-associated signaling in T cells from patients with systemic lupus erythematosus
-
Jury, E.C.; Isenberg, D.A.; Mauri, C.; Ehrenstein, M.R. Atorvastatin restores Lck expression and lipid raft-associated signaling in T cells from patients with systemic lupus erythematosus. J. Immunol., 2006, 177,7416-7422. (Pubitemid 44715112)
-
(2006)
Journal of Immunology
, vol.177
, Issue.10
, pp. 7416-7422
-
-
Jury, E.C.1
Isenberg, D.A.2
Mauri, C.3
Ehrenstein, M.R.4
-
107
-
-
34547839642
-
A pravastatin dose-escalation study in systemic lupus erythematosus
-
DOI 10.1007/s00296-007-0341-6
-
Costenbader, K.H.; Liang, M.H.; Chibnik, L.B.; Aizer, J.; Kwon, H.; Gall, V.; Karlson, E.W. A pravastatin dose-escalation study in systemic lupus erythematosus. Rheumatol. Int., 2007,27,1071-1077. (Pubitemid 47246586)
-
(2007)
Rheumatology International
, vol.27
, Issue.11
, pp. 1071-1077
-
-
Costenbader, K.H.1
Liang, M.H.2
Chibnik, L.B.3
Aizer, J.4
Kwon, H.5
Gall, V.6
Karlson, E.W.7
-
108
-
-
0028939618
-
The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 segment
-
Waisman, A.; Shoenfeld, Y.; Blank, M.; Ruiz, P.J.; Mozes, E. The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 segment. Int. Immunol., 1995;7,689-696.
-
(1995)
Int. Immunol.
, vol.7
, pp. 689-696
-
-
Waisman, A.1
Shoenfeld, Y.2
Blank, M.3
Ruiz, P.J.4
Mozes, E.5
-
109
-
-
38449119975
-
The role of apoptosis in the ameliorating effects of a CDR1-based peptide on lupus manifestations in a mouse model
-
Sharabi, A.; Luger, D.; Ben-David, H.; Dayan, M.; Zinger, H.; Mozes, E. The role of apoptosis in the ameliorating effects of a CDR1-based peptide on lupus manifestations in a mouse model. J. Immunol., 2007,179,4979-4987.
-
(2007)
J. Immunol.
, vol.179
, pp. 4979-4987
-
-
Sharabi, A.1
Luger, D.2
Ben-David, H.3
Dayan, M.4
Zinger, H.5
Mozes, E.6
-
110
-
-
69949159382
-
A tolerogenic peptide down-regulates mature B cells in bone marrow of lupusafflicted mice by inhibition of interleukin-7, leading to apoptosis
-
Ben-David, H.; Sharabi, A.; Parameswaran, R.; Zinger, H.; Mozes, E. A tolerogenic peptide down-regulates mature B cells in bone marrow of lupusafflicted mice by inhibition of interleukin-7, leading to apoptosis. Immunology, 2009,128,245-252.
-
(2009)
Immunology
, vol.128
, pp. 245-252
-
-
Ben-David, H.1
Sharabi, A.2
Parameswaran, R.3
Zinger, H.4
Mozes, E.5
-
111
-
-
34547408930
-
Altered gene expression in mice with lupus treated with edratide, a peptide that ameliorates the disease manifestations
-
DOI 10.1002/art.22736
-
Elmann, A.; Sharabi, A.; Dayan, M.; Zinger, H.; Ophir, R.; Mozes, E. Altered gene expression in mice with lupus treated with edratide, a peptide that ameliorates the disease manifestations. Arthritis Rheum., 2007, 56, 2371-2381. (Pubitemid 47173585)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.7
, pp. 2371-2381
-
-
Elmann, A.1
Sharabi, A.2
Dayan, M.3
Zinger, H.4
Ophir, R.5
Mozes, E.6
-
112
-
-
67349261724
-
Treatment of lupus patients with a tolerogenic peptide, hCDR1 (Edratide): Immunomodulation of gene expression
-
Sthoeger, Z.M.; Sharabi, A.; Molad, Y.; Asher, I.; Zinger, H.; Dayan, M.; Mozes, E. Treatment of lupus patients with a tolerogenic peptide, hCDR1 (Edratide): Immunomodulation of gene expression. J. Autoimmun., 2009,33,77-82.
-
(2009)
J. Autoimmun.
, vol.33
, pp. 77-82
-
-
Sthoeger, Z.M.1
Sharabi, A.2
Molad, Y.3
Asher, I.4
Zinger, H.5
Dayan, M.6
Mozes, E.7
-
113
-
-
79955883535
-
Novel strategy in lupus therapy: From the peptide P140 to Lupuzor
-
Muller, S. Novel strategy in lupus therapy: From the peptide P140 to Lupuzor. Ann Pharm Fr., 2011, 69,151-154.
-
(2011)
Ann Pharm Fr.
, vol.69
, pp. 151-154
-
-
Muller, S.1
-
114
-
-
0345701527
-
T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MRL/lpr mice
-
DOI 10.1002/immu.200310002
-
Monneaux, F.; Lozano, J.M.; Patarroyo, M.E.; Briand, J.P.; Muller, S. T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MR/lpr mice. Eur J Immunol., 2003,33,287-296. (Pubitemid 36267592)
-
(2003)
European Journal of Immunology
, vol.33
, Issue.2
, pp. 287-296
-
-
Monneaux, F.1
Lozano, J.M.2
Patarroyo, M.E.3
Briand, J.-P.4
Muller, S.5
-
115
-
-
40949110876
-
Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K
-
DOI 10.1038/sj.cdd.4402312, PII 4402312, The biology of Hypoxia-inducible factors
-
Dieker, J.; Cisterna, B.; Monneaux, F.; Decossas, M.; van der Vlag, J.; Biggiogera, M.; Muller, S. Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K. Cell Death Differ, 2008,15,793-804. (Pubitemid 351405084)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.4
, pp. 793-804
-
-
Dieker, J.1
Cisterna, B.2
Monneaux, F.3
Decossas, M.4
Van Der Vlag, J.5
Biggiogera, M.6
Muller, S.7
-
116
-
-
65449168745
-
The spliceosomal phosphopeptide P140 controls the lupus disease by interacting with the HSC70 protein and via a mechanism mediated by gammadelta T cells
-
Page, N.; Schall, N.; Strub, J.M.; Quinternet, M.; Chaloin, O.; Décossas, M.; Cung, M.T.; Van Dorsselaer, A.; Briand, J.P.; Muller, S.The spliceosomal phosphopeptide P140 controls the lupus disease by interacting with the HSC70 protein and via a mechanism mediated by gammadelta T cells. PLoS ONE 2009,4,e5273.
-
(2009)
PLoS ONE
, vol.4
-
-
Page, N.1
Schall, N.2
Strub, J.M.3
Quinternet, M.4
Chaloin, O.5
Décossas, M.6
Cung, M.T.7
Van Dorsselaer, A.8
Briand, J.P.9
Muller, S.10
-
117
-
-
79953317423
-
HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus
-
Page, N.; Gros, F.; Schall, N.; Décossas, M.; Bagnard, D.; Briand, J.P.; Muller, S. HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus. Ann Rheum Dis., 2011, 70,837-843.
-
(2011)
Ann Rheum Dis.
, vol.70
, pp. 837-843
-
-
Page, N.1
Gros, F.2
Schall, N.3
Décossas, M.4
Bagnard, D.5
Briand, J.P.6
Muller, S.7
-
118
-
-
79955691840
-
A therapeutic peptide in lupus alters autophagic processes and stability of MHCII molecules in MRL/lpr B cells
-
Page, N.; Gros, F.; Schall, N.; Briand, J.P.; Muller, S. A therapeutic peptide in lupus alters autophagic processes and stability of MHCII molecules in MRL/lpr B cells. Autophagy, 2011, 7, 539-540.
-
(2011)
Autophagy
, vol.7
, pp. 539-540
-
-
Page, N.1
Gros, F.2
Schall, N.3
Briand, J.P.4
Muller, S.5
-
119
-
-
0345701527
-
T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MRL/lpr mice
-
DOI 10.1002/immu.200310002
-
Monneaux, F.; Lozano, J.M.; Patarroyo, M.E.; Briand, J.P.; Muller, S. T cell recognition and therapeutic effects of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MRL/lpr lupus mice. Eur J Immunol, 2003, 33, 287-296. (Pubitemid 36267592)
-
(2003)
European Journal of Immunology
, vol.33
, Issue.2
, pp. 287-296
-
-
Monneaux, F.1
Lozano, J.M.2
Patarroyo, M.E.3
Briand, J.-P.4
Muller, S.5
-
120
-
-
57349101501
-
Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: Results of an early phase II clinical trial
-
Muller, S.; Monneaux, F.; Schall, N.; Rashkov, R.K.; Oparanov, B.A.; Wiesel, P.; Geiger, J.M.; Zimmer, R. Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: Results of an early phase II clinical trial. Arthritis Rheum., 2008,58, 3873-3883.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 3873-3883
-
-
Muller, S.1
Monneaux, F.2
Schall, N.3
Rashkov, R.K.4
Oparanov, B.A.5
Wiesel, P.6
Geiger, J.M.7
Zimmer, R.8
-
121
-
-
70449495408
-
Novel targeted therapies for autoimmunity
-
St Clair, E.W. Novel targeted therapies for autoimmunity. Curr. Opin. Immunol., 2009, 21, 648-657.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 648-657
-
-
St Clair, E.W.1
-
122
-
-
67650175475
-
Costimulation blockade in rheumatic diseases: Where we are?
-
Goeb, V.; Buch, M.H.; Vital, E.M.; Emery, P. Costimulation blockade in rheumatic diseases: Where we are? Curr. Opin. Rheumatol., 2009, 21, 244-250.
-
(2009)
Curr. Opin. Rheumatol.
, vol.21
, pp. 244-250
-
-
Goeb, V.1
Buch, M.H.2
Vital, E.M.3
Emery, P.4
-
123
-
-
77955173179
-
Biologics in the treatment of systemic lupus erythematosus
-
Lateef, A.; Petri, M. Biologics in the treatment of systemic lupus erythematosus. Curr. Opin. Rheumatol., 2010, 22, 504-509.
-
(2010)
Curr. Opin. Rheumatol.
, vol.22
, pp. 504-509
-
-
Lateef, A.1
Petri, M.2
-
124
-
-
0036156661
-
The role of novel T cell costimulatory pathways in autoimmunity and transplantation
-
Yamada, A.; Salama, A.D.; Sayegh, M.H. The role of novel T cell costimulatory pathways in autoimmunity and transplantation. J. Am. Soc. Nephrol., 2002,13,559-575. (Pubitemid 34106301)
-
(2002)
Journal of the American Society of Nephrology
, vol.13
, Issue.2
, pp. 559-575
-
-
Yamada, A.1
Salama, A.D.2
Sayegh, M.H.3
-
125
-
-
34547197857
-
Update on abatacept: A selective costimulation modulator for rheumatoid arthritis
-
DOI 10.1345/aph.1K057
-
Bruce, S.P.; Boyce, E.G. Update on abatacept: A selective costimulation modulator for rheumatoid arthritis. Ann Pharmacother. 2007, 41,1153-1162. (Pubitemid 47122552)
-
(2007)
Annals of Pharmacotherapy
, vol.41
, Issue.7-8
, pp. 1153-1162
-
-
Bruce, S.P.1
Boyce, E.G.2
-
126
-
-
62549154024
-
Abatacept a novel CD80/86-CD28 T cell costimulation modulator, in the treatment of rheumatoid arthritis
-
Korhonen, R.; Moilanen, E. Abatacept, a novel CD80/86-CD28 T cell costimulation modulator, in the treatment of rheumatoid arthritis. Basic Clin. Pharmacol. Toxicol., 2009,104,276-284.
-
(2009)
Basic Clin. Pharmacol. Toxicol.
, vol.104
, pp. 276-284
-
-
Korhonen, R.1
Moilanen, E.2
-
127
-
-
77957682858
-
The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial
-
Merrill, J.T.; Merrill, J.T.; Burgos-Vargas, R.; Westhovens, R.; Chalmers, A.; D'Cruz, D.; Wallace, D.J.; Bae, S.C.; Sigal, L.; Becker, J.C. Kelly, S.; Raghupathi, K.; Li, T.; Peng, Y.; Kinaszczuk, M.; Nash, P. The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial. Arthritis Rheum., 2010,62,3077-3087.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 3077-3087
-
-
Merrill, J.T.1
Merrill, J.T.2
Burgos-Vargas, R.3
Westhovens, R.4
Chalmers, A.5
D'Cruz, D.6
Wallace, D.J.7
Bae, S.C.8
Sigal, L.9
Becker J.C. Kelly, S.10
Raghupathi, K.11
Li, T.12
Peng, Y.13
Kinaszczuk, M.14
Nash, P.15
-
128
-
-
0742269463
-
Monoclonal antibodies in the treatment of autoimmune cytopenias
-
DOI 10.1046/j.0902-4441.2003.00196.x
-
Robak, T. Monoclonal antibodies in the treatment of autoimmune cytopenias. Eur. J. Haematol., 2004, .72, 79-88. (Pubitemid 38161156)
-
(2004)
European Journal of Haematology
, vol.72
, Issue.2
, pp. 79-88
-
-
Robak, T.1
-
129
-
-
16544389341
-
The biology of CD20 and its potential as a target for mAb therapy
-
Cragg, M.S.; Walshe, C.A.; Ivanov, A.O.; Glennie, M.J.The biology of CD20 and its potential as a target for mAb therapy. Curr. Dir. Autoimmun., 2005;8;140-174.
-
(2005)
Curr. Dir. Autoimmun.
, vol.8
, pp. 140-174
-
-
Cragg, M.S.1
Walshe, C.A.2
Ivanov, A.O.3
Glennie, M.J.4
-
130
-
-
78651376557
-
New anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoid malignancies
-
Robak, T.; Robak, E. New anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoid malignancies. BioDrugs, 2011,.25, 13-25.
-
(2011)
BioDrugs
, vol.25
, pp. 13-25
-
-
Robak, T.1
Robak, E.2
-
131
-
-
73949113479
-
Anti-CD20 monoclonal antibodies: Historical and future perspectives
-
Lim, S.H.; Beers, S.A.; French, R.R.; Johnson, P.W.; Glennie, M.J.; Cragg, M.S. Anti-CD20 monoclonal antibodies: Historical and future perspectives. Haematologica., 2010, 95, 135-143.
-
(2010)
Haematologica.
, vol.95
, pp. 135-143
-
-
Lim, S.H.1
Beers, S.A.2
French, R.R.3
Johnson, P.W.4
Glennie, M.J.5
Cragg, M.S.6
-
132
-
-
65249187242
-
A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at University College London Hospital: The first fifty patients
-
Lu, T.Y.; Ng, K.P.; Cambridge, G.; Leandro, M.J.; Edwards, J.C.; Ehrenstein, M.; Isenberg, D.A. A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at University College London Hospital: The first fifty patients. Arthritis Rheum., 2009, 61, 482-487.
-
(2009)
Arthritis Rheum.
, vol.61
, pp. 482-487
-
-
Lu, T.Y.1
Ng, K.P.2
Cambridge, G.3
Leandro, M.J.4
Edwards, J.C.5
Ehrenstein, M.6
Isenberg, D.A.7
-
133
-
-
46849096714
-
B cell depletion therapy in systemic lupus erythaematosus: Relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response
-
DOI 10.1136/ard.2007.079418
-
Cambridge, G.; Isenberg, D.A.; Edwards, J.C.; Leandro, M.J.; Migone, T.S.; Teodorescu, M.; Stohl, W. B cell depletion therapy in systemic lupus erythematosus: Relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response. Ann. Rheum. Dis,. 2008, 67, 1011-1016. (Pubitemid 351956665)
-
(2008)
Annals of the Rheumatic Diseases
, vol.67
, Issue.7
, pp. 1011-1016
-
-
Cambridge, G.1
Isenberg, D.A.2
Edwards, J.C.W.3
Leandro, M.J.4
Migone, T.-S.5
Teodorescu, M.6
Stohl, W.7
-
134
-
-
63049098491
-
Monoclonal antibodies in the treatment of systemic lupus erythematosus
-
Robak, E. ; Robak, T. Monoclonal antibodies in the treatment of systemic lupus erythematosus. Curr. Drug Targets, 2009, 10, 26-37.
-
(2009)
Curr. Drug Targets
, vol.10
, pp. 26-37
-
-
Robak, E.1
Robak, T.2
-
135
-
-
77955386129
-
Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: Results of a randomized, double-blind, placebo-controlled, phase I/II study
-
Østergaard, M.; Baslund, B.; Rigby, W.; Rojkovich, B.; Jorgensen, C.; Dawes, P.T.; Wiell, C.; Wallace, D.J.; Tamer, S.C.; Kastberg, H.; Petersen, J.; Sierakowski, S. Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: Results of a randomized, double-blind, placebo-controlled, phase I/II study. Arthritis Rheum., 2010, 62, 2227-2238.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2227-2238
-
-
Østergaard, M.1
Baslund, B.2
Rigby, W.3
Rojkovich, B.4
Jorgensen, C.5
Dawes, P.T.6
Wiell, C.7
Wallace, D.J.8
Tamer, S.C.9
Kastberg, H.10
Petersen, J.11
Sierakowski, S.12
-
136
-
-
60849089338
-
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti- CD20 monoclonal antibody
-
Goldenberg, D.M.; Rossi, E.A., Stein, R.; Cardillo, T.M.; Czuczman, M.S.; Hernandez-Ilizaliturri, F.J.; Hansen, H.J.; Chang, C.H. Properties and structure-function relationships of veltuzumab (hA20), a humanized anti- CD20 monoclonal antibody. Blood, 2009, 113, 1062-1070.
-
(2009)
Blood
, vol.113
, pp. 1062-1070
-
-
Goldenberg, D.M.1
Rossi, E.A.2
Stein, R.3
Cardillo, T.M.4
Czuczman, M.S.5
Hernandez-Ilizaliturri, F.J.6
Hansen, H.J.7
Chang, C.H.8
-
137
-
-
70249106098
-
Humanized anti-CD20 antibody, veltuzumab, in refractory/recurrent non-Hodgkin's lymphoma: Phase I/II results
-
Morschhauser, F.; Leonard, J.P.; Fayad, L.; , Coiffier, B.; Petillon, M.O.; Coleman, M.; Schuster, S.J.; Dyer, M.J.; Horne, H.; Teoh, N.; Wegener, W.A.; Goldenberg, D.M. Humanized anti-CD20 antibody, veltuzumab, in refractory/recurrent non-Hodgkin's lymphoma: Phase I/II results. J. Clin. Oncol., 2009, 27, 3346-3353.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 3346-3353
-
-
Morschhauser, F.1
Leonard, J.P.2
Fayad L.3
4
Coiffier, B.5
Petillon, M.O.6
Coleman, M.7
Schuster, S.J.8
Dyer, M.J.9
Horne, H.10
Teoh, N.11
Wegener, W.A.12
Goldenberg, D.M.13
-
138
-
-
67650345281
-
Ocrelizumab: A step forward in the evolution of B-cell therapy
-
Kausar, F.; Mustafa, K.; Sweis, G.; Sawaqed, R.; Alawneh, K.;, Salloum, R.; Badaracco, M.; Niewold, T.B.; Sweiss, N.J. Ocrelizumab: A step forward in the evolution of B-cell therapy. Expert. Opin. Biol. Ther, 2009, 9, 889-895.
-
(2009)
Expert. Opin. Biol. Ther
, vol.9
, pp. 889-895
-
-
Kausar, F.1
Mustafa, K.2
Sweis, G.3
Sawaqed, R.4
Alawneh, K.5
Salloum, R.6
Badaracco, M.7
Niewold, T.B.8
Sweiss, N.J.9
-
139
-
-
51849148443
-
Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study
-
ACTION Study Group.
-
Genovese, M.C.; Kaine, J.L.; Lowenstein, M.B.; Del Giudice, J.; Baldassare, A.; Schechtman, J.; Fudman, E.; Kohen, M.; Gujrathi, S.; Trapp, R.G.; Sweiss, N.J.; Spaniolo, G.; Dummer, W.; ACTION Study Group. Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study. Arthritis Rheum, 2008, 58, 2652-2661.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2652-2661
-
-
Genovese, M.C.1
Kaine, J.L.2
Lowenstein, M.B.3
Del Giudice, J.4
Baldassare, A.5
Schechtman, J.6
Fudman, E.7
Kohen, M.8
Gujrathi, S.9
Trapp, R.G.10
Sweiss, N.J.11
Spaniolo, G.12
Dummer, W.13
-
140
-
-
77956236829
-
Three different B-cell depletion (anti-CD20 monoclonal antibodies) treatments for severe resistant systemic lupus erythematosus
-
Faria, R.M. & Isenberg, DA. Three different B-cell depletion (anti-CD20 monoclonal antibodies) treatments for severe resistant systemic lupus erythematosus. Lupus, 2010, 19, 1256-1257.
-
(2010)
Lupus
, vol.19
, pp. 1256-1257
-
-
Faria, R.M.1
Isenberg, D.A.2
-
141
-
-
77953507105
-
The future of CD20 monoclonal antibody therapy in B-cell malignancies
-
Czuczman, M.S., Gregory S.A. The future of CD20 monoclonal antibody therapy in B-cell malignancies. Leuk. Lymphoma., 2010, 51, 983-994.
-
(2010)
Leuk. Lymphoma.
, vol.51
, pp. 983-994
-
-
Czuczman, M.S.1
Gregory, S.A.2
-
142
-
-
67650657179
-
GA-101, a third-generation, humanized and glyco-engineered anti- CD20 mAb for the treatment of B-cell lymphoid malignancies
-
Robak, T. GA-101, a third-generation, humanized and glyco-engineered anti- CD20 mAb for the treatment of B-cell lymphoid malignancies. Curr Opin Investig Drugs, 2009, 10, 588-596.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 588-596
-
-
Robak, T.1
-
143
-
-
79953183947
-
Mechanism of action of type II, glycoengineered, anti- CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab
-
Bologna, L.; Gotti, E.; Manganini, M.; Rambaldi, A.; Intermesoli, T.; Introna, M.; Golay, J. Mechanism of Action of Type II, Glycoengineered, Anti- CD20 Monoclonal Antibody GA101 in B-Chronic Lymphocytic Leukemia Whole Blood Assays in Comparison with Rituximab and Alemtuzumab. J. Immunol., 2011, 186, 3762-3769.
-
(2011)
J. Immunol.
, vol.186
, pp. 3762-3769
-
-
Bologna, L.1
Gotti, E.2
Manganini, M.3
Rambaldi, A.4
Intermesoli, T.5
Introna, M.6
Golay, J.7
-
144
-
-
76749140818
-
TRU-015, a fusion protein derived from an anti-CD20 antibody, for the treatment of rheumatoid arthritis
-
Rubbert-Roth, A. TRU-015, a fusion protein derived from an anti-CD20 antibody, for the treatment of rheumatoid arthritis. Curr. Opin. Mol. Ther., 2010, 12, 115-123.
-
(2010)
Curr. Opin. Mol. Ther.
, vol.12
, pp. 115-123
-
-
Rubbert-Roth, A.1
-
145
-
-
71249091846
-
TRU-016, a humanized anti-CD37 IgG fusion protein for the potential treatment of B-cell malignancies
-
Robak, T.; Robak, P.; Smolewski, P. TRU-016, a humanized anti-CD37 IgG fusion protein for the potential treatment of B-cell malignancies. Curr. Opin. Investig. Drugs, 2009, 10, 1383-1390.
-
(2009)
Curr. Opin. Investig. Drugs
, vol.10
, pp. 1383-1390
-
-
Robak, T.1
Robak, P.2
Smolewski, P.3
-
146
-
-
65249090847
-
CD20- directed small modular immunopharmaceutical, TRU-015, depletes normal and malignant B cells
-
Hayden-Ledbetter, M.S.; Cerveny, C.G.; Espling, E.; Brady, W.A.; Grosmaire, L.S.; Tan, P.; Bader, R.; Slater, S.; Nilsson, C.A.; Barone, D.S.; Simon, A.; Bradley, C.; Thompson, P.A.; Wahl, A.F.; Ledbetter, J.A. CD20- directed small modular immunopharmaceutical, TRU-015, depletes normal and malignant B cells. Clin. Cancer Res., 2009, 15, 2739-2746.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2739-2746
-
-
Hayden-Ledbetter, M.S.1
Cerveny, C.G.2
Espling, E.3
Brady, W.A.4
Grosmaire, L.S.5
Tan, P.6
Bader, R.7
Slater, S.8
Nilsson, C.A.9
Barone, D.S.10
Simon, A.11
Bradley, C.12
Thompson, P.A.13
Wahl, A.F.14
Ledbetter, J.A.15
-
147
-
-
56149114691
-
Pharmacokinetic and pharmacodynamic properties of TRU-015, a CD20-directed small modular immunopharmaceutical protein therapeutic, in patients with rheumatoid arthritis: A phase I, open-label, dose-escalation clinical study
-
Burge, D.J.; Bookbinder, S.A.; Kivitz, A.J.; Fleischmann, R.M.; Shu, C.; Bannink, J. Pharmacokinetic and pharmacodynamic properties of TRU-015, a CD20-directed small modular immunopharmaceutical protein therapeutic, in patients with rheumatoid arthritis: A phase I, open-label, dose-escalation clinical study. Clin. Ther, 2008, 30, 1806-1816.
-
(2008)
Clin. Ther
, vol.30
, pp. 1806-1816
-
-
Burge, D.J.1
Bookbinder, S.A.2
Kivitz, A.J.3
Fleischmann, R.M.4
Shu, C.5
Bannink, J.6
-
148
-
-
36649038725
-
Systemic lupus erythematosus: modern strategies for management - A moving target
-
DOI 10.1016/j.berh.2007.09.002, PII S1521694207001040, Connective Tissue Diseases
-
King, J.K. ; Hahn, B.H. Systemic lupus erythematosus: Modern strategies for management: A moving target. Best Pract. Res. Clin. Rheumatol,. 2007, 21, 971-987. (Pubitemid 350194036)
-
(2007)
Best Practice and Research in Clinical Rheumatology
, vol.21
, Issue.6
, pp. 971-987
-
-
King, J.K.1
Hahn, B.H.2
-
149
-
-
33645715993
-
The reduction of serum B-lymphocyte activating factor levels following quinacrine add-on therapy in systemic lupus erythematosus
-
Toubi, E.; Kessel, A.; Rosner, I.; Rozenbaum, M.; Paran, D.; Shoenfeld, Y. The reduction of serum B-lymphocyte activating factor levels following quinacrine add-on therapy in systemic lupus erythematosus. Scand. J. Immunol., 2006, 63, 299-303
-
(2006)
Scand. J. Immunol.
, vol.63
, pp. 299-303
-
-
Toubi, E.1
Kessel, A.2
Rosner, I.3
Rozenbaum, M.4
Paran, D.5
Shoenfeld, Y.6
-
150
-
-
78649955057
-
Belimumab: A BLySspecific inhibitor for systemic lupus erythematosus
-
Wiglesworth, A.K.; Ennis, K.M. & Kockler, D.R. Belimumab: A BLySspecific inhibitor for systemic lupus erythematosus. Ann. Pharmacother., 2010, 44, 1955-1961.
-
(2010)
Ann. Pharmacother.
, vol.44
, pp. 1955-1961
-
-
Wiglesworth, A.K.1
Ennis, K.M.2
Kockler, D.R.3
-
151
-
-
0242495115
-
Generation and Characterization of LymphoStat-B, a Human Monoclonal Antibody That Antagonizes the Bioactivities of B Lymphocyte Stimulator
-
DOI 10.1002/art.11299
-
Baker, K.P.; Edwards, B.M.; Main, S.H.; Choi, G.H.; Wager, R.E.;, Halpern, W.G.; Lappin, P.B.; Riccobene, T.; Abramian, D.; Sekut, L.; Sturm, B.; Poortman, C.; Minter, R.R.; Dobson, C.L.; Williams, E.; Carmen, S.; Smith, R.; Roschke, V.; Hilbert, D.M.; Vaughan, T.J.; Albert, V.R. Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator. Arthritis Rheum., 2003, 48, 3253-3265. (Pubitemid 37409340)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.11
, pp. 3253-3265
-
-
Baker, K.P.1
Edwards, B.M.2
Main, S.H.3
Choi, G.H.4
Wager, R.E.5
Halpern, W.G.6
Lappin, P.B.7
Riccobene, T.8
Abramian, D.9
Sekut, L.10
Sturm, B.11
Poortman, C.12
Minter, R.R.13
Dobson, C.L.14
Williams, E.15
Carmen, S.16
Smith, R.17
Roschke, V.18
Hilbert, D.M.19
Vaughan, T.J.20
Albert, V.R.21
more..
-
152
-
-
79952070370
-
BLISS-52 Study Group. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: A randomised, placebo-controlled, phase 3 trial
-
Navarra, S.V.; Guzmán, R.M.; Gallacher, A.E.; Hall, S.; Levy, R.A.; Jimenez, R.E.; Li, E.K.; Thomas, M.; Kim, H.Y.; León, M.G.; Tanasescu, C.; Nasonov, E.; Lan, J.L.; Pineda, L.; Zhong, Z.J.; Freimuth, W.; Petri, M.A.; BLISS-52 Study Group. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: A randomised, placebo-controlled, phase 3 trial. Lancet, 2011, 377, 721-731.
-
(2011)
Lancet
, vol.377
, pp. 721-731
-
-
Navarra, S.V.1
Guzmán, R.M.2
Gallacher, A.E.3
Hall, S.4
Levy, R.A.5
Jimenez, R.E.6
Li, E.K.7
Thomas, M.8
Kim, H.Y.9
León, M.G.10
Tanasescu, C.11
Nasonov, E.12
Lan, J.L.13
Pineda, L.14
Zhong, Z.J.15
Freimuth, W.16
Petri, M.A.17
-
153
-
-
0034634625
-
Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS
-
Wu, Y.; Bressette, D.; Carrell, J.A.; Kaufman, T.; Feng, P.; Taylor, K.; Gan, Y.; Cho, Y.H.; Garcia, A.D.; Gollatz, E.; Dimke, D.; LaFleur, D.; Migone, T.S.; Nardelli, B.; Wei, P.; Ruben, S.M.; Ullrich, S.J.; Olsen, H.S.; Kanakaraj, P.; Moore, P.A.; Baker, K.P. Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. J Biol Chem.; 2000, 275, 35478-35485.
-
(2000)
J Biol Chem.
, vol.275
, pp. 35478-35485
-
-
Wu, Y.1
Bressette, D.2
Carrell, J.A.3
Kaufman, T.4
Feng, P.5
Taylor, K.6
Gan, Y.7
Cho, Y.H.8
Garcia, A.D.9
Gollatz, E.10
Dimke, D.11
LaFleur, D.12
Migone, T.S.13
Nardelli, B.14
Wei, P.15
Ruben, S.M.16
Ullrich, S.J.17
Olsen, H.S.18
Kanakaraj, P.19
Moore, P.A.20
Baker, K.P.21
more..
-
154
-
-
65149106325
-
An exploratory doseescalating study investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenous atacicept in patients with systemic lupus erythematosus
-
Pena-Rossi, C.; Nasonov, E.; Stanislav, M.; Yakusevich, V.; Ershova, O.; Lomareva, N.; Saunders, H.; Hill, J.; Nestorov, I. An exploratory doseescalating study investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenous atacicept in patients with systemic lupus erythematosus. Lupus, 2009,18,547-555.
-
(2009)
Lupus
, vol.18
, pp. 547-555
-
-
Pena-Rossi, C.1
Nasonov, E.2
Stanislav, M.3
Yakusevich, V.4
Ershova, O.5
Lomareva, N.6
Saunders, H.7
Hill, J.8
Nestorov, I.9
-
155
-
-
37149032474
-
Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial
-
DOI 10.1002/art.23047
-
Dall'Era, M.; Chakravarty, E.; Wallace, D.; Genovese, M.; Weisman, M.; Kavanaugh, A.; Kalunian, K.; Dhar, P.; Vincent, E.; Pena-Rossi, C.; Wofsy, D. Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus rythematosus: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial. Arthritis Rheum., 2007, 56,4142-4150. (Pubitemid 350262342)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.12
, pp. 4142-4150
-
-
Dall'Era, M.1
Chakravarty, E.2
Wallace, D.3
Genovese, M.4
Weisman, M.5
Kavanaugh, A.6
Kalunian, K.7
Dhar, P.8
Vincent, E.9
Pena-Rossi, C.10
Wofsy, D.11
Alum, N.12
Dubois, A.13
Kinnman, N.14
Picard, M.15
Bortolotti, A.16
O'Grady, L.17
Hill, J.18
Nestorov, I.19
Salmon, E.20
more..
-
156
-
-
73949102012
-
Pharmacokinetics and immunoglobulin response of subcutaneous and intravenous atacicept in patients with systemic lupus erythematosus
-
Nestorov, I.; Papasouliotis, O.; Pena Rossi, C.; Munafo, A. Pharmacokinetics and immunoglobulin response of subcutaneous and intravenous atacicept in patients with systemic lupus erythematosus. J Pharm Sci. 2010,99,524-538.
-
(2010)
J Pharm Sci.
, vol.99
, pp. 524-538
-
-
Nestorov, I.1
Papasouliotis, O.2
Pena Rossi, C.3
Munafo, A.4
-
157
-
-
47049112010
-
The role of tumor necrosis factor-alpha in systemic lupus erythematosus
-
Aringer M, Smolen JS. The role of tumor necrosis factor-alpha in systemic lupus erythematosus. Arthritis Res Ther. 2008,10, 202.
-
(2008)
Arthritis Res Ther.
, vol.10
, pp. 202
-
-
Aringer, M.1
Smolen, J.S.2
-
158
-
-
77953555514
-
Cytokines as therapeutic targets in SLE
-
Rönnblom, L.; Elkon, K.B. Cytokines as therapeutic targets in SLE. Nat Rev Rheumatol., 2010, 6, 339-347.
-
(2010)
Nat Rev Rheumatol.
, vol.6
, pp. 339-347
-
-
Rönnblom, L.1
Elkon, K.B.2
-
159
-
-
0036206671
-
Increased bioactive TNF in human systemic lupus erythematosus: Associations with cell death
-
DOI 10.1191/0961203302lu160oa
-
Aringer, M.; Feierl, E.; Steiner, G.; Stummvoll, G.H.; Höfler, E.; Steiner, C.W.; Radda, I.; Smole, J.S.; Graninger, W.B.Increased bioactive TNF in human systemic lupus erythematosus: Associations with cell death. Lupus, 2002,11,102-108. (Pubitemid 34259440)
-
(2002)
Lupus
, vol.11
, Issue.2
, pp. 102-108
-
-
Aringerl, M.1
Feierl, E.2
Steiner, G.3
Stummvoll, G.H.4
Hofler, E.5
Steiner, C.W.6
Radda, I.7
Smolen, J.S.8
Graninger, W.B.9
-
160
-
-
77955409102
-
Anti-TNF-alpha therapies in systemic lupus erythematosus
-
Epub 2010 Jun 22
-
Zhu, L.J.; Yang, X.; Yu, X.Q. Anti-TNF-alpha therapies in systemic lupus erythematosus. J Biomed Biotechnol. 2010;2010:465898. Epub 2010 Jun 22.
-
(2010)
J Biomed Biotechnol.
, vol.2010
, pp. 465898
-
-
Zhu, L.J.1
Yang, X.2
Yu, X.Q.3
-
161
-
-
0030586573
-
Inhibition of Superantigen-Induced Proinflammatory Cytokine Production and Inflammatory Arthritis in MRL-Ipr/Ipr Mice by a Transcriptional Inhibitor of TNF-α
-
Edwards, C.K 3rd.; Zhou, T.; Zhang, J.; Baker, T.J.; De M, Long, R.E.; Borcherding, D.R.; Bowlin, T.L.; Bluethmann, H.; Mountz, J.D. Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-α Journal of Immunology, 1996,157,1758-1772. (Pubitemid 126449121)
-
(1996)
Journal of Immunology
, vol.157
, Issue.4
, pp. 1758-1772
-
-
Edwards III, C.K.1
Zhou, T.2
Zhang, J.3
Baker, T.J.4
De, M.5
Long, R.E.6
Borcherding, D.R.7
Bowlin, T.L.8
Bluethmann, H.9
Mountz, J.D.10
-
162
-
-
0038054603
-
A lupus-like syndrome associated with infliximab therapy
-
DOI 10.1097/00054725-200305000-00005
-
Klapman, J.B.; Ene-Stroescu, D.; Becker, M.A.; Hanauer, S.B. A lupus-like syndrome associated with infliximab therapy. Inflamm Bowel Dis., 2003, 9, 176-178. (Pubitemid 36592448)
-
(2003)
Inflammatory Bowel Diseases
, vol.9
, Issue.3
, pp. 176-178
-
-
Klapman, J.B.1
Ene-Stroescu, D.2
Becker, M.A.3
Hanauer, S.B.4
-
163
-
-
79958145733
-
Infliximab: 12 years of experience
-
Smolen, J.S.; Emery, P. Infliximab: 12 years of experience. Arthritis Res Ther., 2011,13 Suppl 1, S2.
-
(2011)
Arthritis Res Ther.
, vol.13
, Issue.SUPPL. 1
-
-
Smolen, J.S.1
Emery, P.2
-
164
-
-
67049162417
-
Efficacy and safety of infliximab in active SLE: A pilot study
-
Uppal, S.S.; Hayat, S.J.; Raghupathy, R. Efficacy and safety of infliximab in active SLE: A pilot study. Lupus. ,2009,18,690-697A.
-
(2009)
Lupus.
, vol.18
-
-
Uppal, S.S.1
Hayat, S.J.2
Raghupathy, R.3
-
165
-
-
73349117550
-
Adverse events and efficacy of TNF-alpha blockade with infliximab in patients with systemic lupus erythematosus: Long-term follow-up of 13 patients
-
Aringer, M.; Houssiau, F.; Gordon, C.; Graninger, W.B.; Voll, R.E.; Rath, E.; Steiner, G.; Smolen, J.S. Adverse events and efficacy of TNF-alpha blockade with infliximab in patients with systemic lupus erythematosus: Long-term follow-up of 13 patients. Rheumatology, 2009,48,1451-1454.
-
(2009)
Rheumatology
, vol.48
, pp. 1451-1454
-
-
Aringer, M.1
Houssiau, F.2
Gordon, C.3
Graninger, W.B.4
Voll, R.E.5
Rath, E.6
Steiner, G.7
Smolen, J.S.8
-
166
-
-
77957230573
-
Tumor necrosis factor-alpha antagonist etanercept decreases blood pressure and protects the kidney in a mouse model of systemic lupus erythematosus
-
Venegas-Pont, M.; Manigrasso, M.B.; Grifoni, S.C.; LaMarca, B.B.; Maric, C.; Racusen, L.C.; Glover, P.H.; Jones, A.V.; Drummond, H.A.; Ryan, M.J. Tumor necrosis factor-alpha antagonist etanercept decreases blood pressure and protects the kidney in a mouse model of systemic lupus erythematosus. Hypertension, 2010 ,56, 643-649.
-
(2010)
Hypertension
, vol.56
, pp. 643-649
-
-
Venegas-Pont, M.1
Manigrasso, M.B.2
Grifoni, S.C.3
LaMarca, B.B.4
Maric, C.5
Racusen, L.C.6
Glover, P.H.7
Jones, A.V.8
Drummond, H.A.9
Ryan, M.J.10
-
167
-
-
0037116836
-
Drug-induced systemic lupus erythematosus associated with etanercept therapy
-
DOI 10.1016/S0140-6736(02)07714-0
-
Shakoor, N.; Michalska, M.; Harris, C.A.; Block, J.A. Drug-induced systemic lupus eythematosus associated with etanercept therapy. Lancet, 2002,359,579-580. (Pubitemid 34178442)
-
(2002)
Lancet
, vol.359
, Issue.9306
, pp. 579-580
-
-
Shakoor, N.1
Michalska, M.2
Harris, C.A.3
Block, J.A.4
-
168
-
-
17144368788
-
Proliferative lupus nephritis and leukocytoclastic vasculitis during treatment with etanercept
-
Mor, A.; Bingham, C 3rd.; Barisoni, L.; Lydon, E.; Belmont, H.M. Proliferative lupus nephritis and leukocytoclastic vasculitis during treatment with etanercept. J Rheumatol., 2005, 32, 740-743. (Pubitemid 40524710)
-
(2005)
Journal of Rheumatology
, vol.32
, Issue.4
, pp. 740-743
-
-
Mor, A.1
Bingham III, C.O.2
Barisoni, L.3
Lydon, E.4
Belmont, H.M.5
-
169
-
-
0032238891
-
Association of interferon gamma, tumor necrosis factor alpha and interleukin 6 serum levels with systemic lupus erythematosus activity
-
Robak, E.; Sysa-Jedrzejewska, A.; Dziankowska, B.; Torzecka, D.; Chojnowski, K.; Robak, T. Association of interferon gamma, tumor necrosis factor alpha and interleukin 6 serum levels with systemic lupus erythematosus activity. Arch Immunol Ther Exp (Warsz)., 1998,46,375-380.
-
(1998)
Arch Immunol Ther Exp (Warsz).
, vol.46
, pp. 375-380
-
-
Robak, E.1
Sysa-Jedrzejewska, A.2
Dziankowska, B.3
Torzecka, D.4
Chojnowski, K.5
Robak, T.6
-
170
-
-
0033976316
-
Dichotomic effects of IFN-γ on the development of systemic lupus erythematosus-like syndrome in MRL-lpr/lpr mice
-
DOI 10.1002/1521-4141(200002)30:2<438::AID-IMMU438>3.0.CO;2-D
-
Nicoletti, F.; Di Marco, R.; Zaccone, P.; Xiang, M.; Magro, G.; Grasso, S.; Morrone, S.; Santoni, A.; Shoenfeld, Y.; Garotta, G.; Meroni, P. Dichotomic effects of IFN-a on the development of systemic lupus erythematosus-like syndrome in MRL-lpr/lpr mice. Eur. J. Immunol., 2000,30,438-447. (Pubitemid 30098836)
-
(2000)
European Journal of Immunology
, vol.30
, Issue.2
, pp. 438-447
-
-
Nicoletti, F.1
Di Marco, R.2
Zaccone, P.3
Xiang, M.4
Magro, G.5
Grasso, S.6
Morrone, S.7
Santoni, A.8
Shoenfeld, Y.9
Garotta, G.10
Meroni, P.11
-
171
-
-
2342491490
-
Suppressive oligonucleotides protect against collagen-induced arthritis in mice
-
DOI 10.1002/art.20263
-
Dong, L.; Ito, S-I.; Ishii, K.J.; Klinman, D.M. Suppressive oligonucleotides protect against collagen-induced arthritis in mice. Arthritis and Rheumatism., 2004,50,1686-1689. (Pubitemid 38608092)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.5
, pp. 1686-1689
-
-
Dong, L.1
Ito, S.-I.2
Ishii, K.J.3
Klinman, D.M.4
-
172
-
-
32444451688
-
The type I interferon system in systemic lupus erythematosus
-
DOI 10.1002/art.21571
-
Ronnblom, L.; Eloranta, M.L.; Alm, G.V. The type I interferon system in systemic lupus erythematosus. Arthritis Rheum. 2006,54,408-420. (Pubitemid 43228615)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.2
, pp. 408-420
-
-
Ronnblom, L.1
Eloranta, M.-L.2
Alm, G.V.3
-
173
-
-
0034533825
-
Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
-
DOI 10.1191/096120300674499064
-
Bengtsson, A.A.; Sturfelt, G.; Truedsson, L.; Blomberg, J.; Alm, G.; Vallin, H.; Rönnblom, L. Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus, 2000, 9, 664-671 (Pubitemid 32011791)
-
(2000)
Lupus
, vol.9
, Issue.9
, pp. 664-671
-
-
Bengtsson, A.A.1
Sturfelt, G.2
Truedsson, L.3
Blomberg, J.4
Alm, G.5
Vallin, H.6
Ronnblom, L.7
-
174
-
-
80053562466
-
Safety profile, pharmacokinetics, immunogenicity, and clinical activity of sifalimumab, in systemic lupus erythematosus: A phase I, multicentre, double-blind randomised study
-
for the Lupus Interferon Skin Activity (LISA) Study Investigators. Jul 27. Epub ahead of print]
-
Merrill, J.T, Wallace, D.J.; Petri, M.; Kirou, K.A.; Yao, Y.; White, W.I.; Robbie, G.; Levin, R.; Berney, S.M.; Chindalore, V.; Olsen, N.; Richman, L.; Le, C.; Jallal, B.; White, B.; for the Lupus Interferon Skin Activity (LISA) Study Investigators. Safety profile, pharmacokinetics, immunogenicity, and clinical activity of sifalimumab, in systemic lupus erythematosus: A phase I, multicentre, double-blind randomised study. Ann Rheum Dis., 2011, Jul 27. Epub ahead of print].
-
(2011)
Ann Rheum Dis.
-
-
Merrill, J.T.1
Wallace, D.J.2
Petri, M.3
Kirou, K.A.4
Yao, Y.5
White, W.I.6
Robbie, G.7
Levin, R.8
Berney, S.M.9
Chindalore, V.10
Olsen, N.11
Richman, L.12
Le, C.13
Jallal, B.14
White, B.15
-
175
-
-
0033808893
-
Cytokine production, serum levels and disease activity in systemic lupus erythematosus
-
Gröndal, G.; Gunnarsson, I.; Rönnelid, J.; Rogberg, S.; Klareskog, L.; Lundberg, I. Cytokine production, serum levels and disease activity in systemic lupus erythematosus. Clin Exp Rheumatol., 2000,18,565-570.
-
(2000)
Clin Exp Rheumatol.
, vol.18
, pp. 565-570
-
-
Gröndal, G.1
Gunnarsson, I.2
Rönnelid, J.3
Rogberg, S.4
Klareskog, L.5
Lundberg, I.6
-
176
-
-
79751520384
-
Tocilizumab: A review of its safety and efficacy in rheumatoid arthritis
-
Jones, G.; Ding, C. Tocilizumab: A review of its safety and efficacy in rheumatoid arthritis. Clin Med. Insights Arthritis Musculoskelet Disord., 2010, 19,81-89.
-
(2010)
Clin Med. Insights Arthritis Musculoskelet Disord.
, vol.19
, pp. 81-89
-
-
Jones, G.1
Ding, C.2
-
177
-
-
33750011260
-
Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus
-
DOI 10.1111/j.1365-2567.2006.02433.x
-
Liang, B.; Gardner, D.B.; Griswold, D.E. Bugelski, P.J.; Song, X.Y. Antiinterleukin- 6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus. Immunology, 2006, 119, 296-305. (Pubitemid 44571047)
-
(2006)
Immunology
, vol.119
, Issue.3
, pp. 296-305
-
-
Liang, B.1
Gardner, D.B.2
Griswold, D.E.3
Bugelski, P.J.4
Song, X.Y.R.5
-
178
-
-
75749113331
-
Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study
-
Illei, G.G; Shirota, Y.; Yarboro, C.H.; Daruwalla, J.; Tackey, E.; Takada, K.; Fleisher, T.; Balow, J.E.; Lipsky, P.E. Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study. Arthritis Rheum., 2010, 62, 542-552.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 542-552
-
-
Illei, G.G.1
Shirota, Y.2
Yarboro, C.H.3
Daruwalla, J.4
Tackey, E.5
Takada, K.6
Fleisher, T.7
Balow, J.E.8
Lipsky, P.E.9
-
179
-
-
70249131176
-
Human Genome Sciences trial data wow lupus community
-
Ratner, M. Human Genome Sciences trial data wow lupus community. Nat Biotechnol. 2009, 27, 779-780.
-
(2009)
Nat Biotechnol.
, vol.27
, pp. 779-780
-
-
Ratner, M.1
-
180
-
-
79960182099
-
Pharmacokinetics pharmacodynamics and safety of a human anti-IL-6 monoclonal antibody (sirukumab) in healthy subjects in a first-in-human study
-
Xu, Z., Bouman-Thio, E., Comisar, C., Frederick, B., Van Hartingsveldt, B., Marini, J.C., Davis, H.M., Zhou, H. Pharmacokinetics, pharmacodynamics and safety of a human anti-IL-6 monoclonal antibody (sirukumab) in healthy subjects in a first-in-human study. Br J Clin Pharmacol. 2011, 72, 270-281.
-
(2011)
Br J Clin Pharmacol.
, vol.72
, pp. 270-281
-
-
Xu, Z.1
Bouman-Thio, E.2
Comisar, C.3
Frederick, B.4
Van Hartingsveldt, B.5
Marini, J.C.6
Davis, H.M.7
Zhou, H.8
-
181
-
-
34347402262
-
Eculizumab
-
Parker, C.J.; Kar, S. & Kirkpatrick, P. Eculizumab. Nat. Rev. Drug Discov., 2007, 6, 515-625.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 515-625
-
-
Parker, C.J.1
Kar, S.2
Kirkpatrick, P.3
|