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Volumn 44, Issue 12, 2010, Pages 1955-1961

Belimumab: A BLyS-specific inhibitor for systemic lupus erythematosus

Author keywords

B lymphocyte stimulators; Belimumab; Benlysta; BLyS specific inhibitors; Systemic lupus erythematosus

Indexed keywords

AZATHIOPRINE; B CELL ACTIVATING FACTOR; BELIMUMAB; BENLYSTA; HYDROXYCHLOROQUINE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; PREDNISONE; UNCLASSIFIED DRUG;

EID: 78649955057     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1P360     Document Type: Review
Times cited : (24)

References (37)
  • 1
    • 78649933126 scopus 로고    scopus 로고
    • accessed 2010 Aug 2
    • Lupus Foundation of America. Statistics on lupus. http://www.lupus.org/ webmodules/webarticlesnet/templates/new-newsroomreporters.aspx?articleid= 247&zoneid=60 (accessed 2010 Aug 2).
    • Statistics on Lupus
  • 2
    • 38149052992 scopus 로고    scopus 로고
    • Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II
    • for the National Arthritis Data Workgroup
    • Lawrence RC, Felson DT, Helmick CG, et al., for the National Arthritis Data Workgroup. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: part II. Arthritis Rheum 2008; 58:26-35.
    • (2008) Arthritis Rheum , vol.58 , pp. 26-35
    • Lawrence, R.C.1    Felson, D.T.2    Helmick, C.G.3
  • 3
    • 24344491492 scopus 로고    scopus 로고
    • Assessment of patients with systemic lupus erythematosus and the use of lupus disease activity indices
    • Griffiths B, Mosca M, Gordon C. Assessment of patients with systemic lupus erythematosus and the use of lupus disease activity indices. Best Pract Res Clin Rheumatol 2005;19:658-708.
    • (2005) Best Pract Res Clin Rheumatol , vol.19 , pp. 658-708
    • Griffiths, B.1    Mosca, M.2    Gordon, C.3
  • 4
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
    • letter
    • Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus (letter). Arthritis Rheum 1997;40:1725.
    • (1997) Arthritis Rheum , vol.40 , pp. 1725
    • Hochberg, M.C.1
  • 5
    • 49749200274 scopus 로고
    • Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus
    • Merrell M, Shulman LE. Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus. J Chronic Dis 1955;1:12-32.
    • (1955) J Chronic Dis , vol.1 , pp. 12-32
    • Merrell, M.1    Shulman, L.E.2
  • 6
    • 0029013185 scopus 로고
    • Mortality studies in systemic lupus erythematosus: Results from a single center. II. Predictor variables for mortality
    • Abu-Shakra M, Urowitz MB, Gladman DD, Gough J. Mortality studies in systemic lupus erythematosus: results from a single center. II. Predictor variables for mortality. J Rheumatol 1995;22:1265-70.
    • (1995) J Rheumatol , vol.22 , pp. 1265-1270
    • Abu-Shakra, M.1    Urowitz, M.B.2    Gladman, D.D.3    Gough, J.4
  • 8
    • 78649931261 scopus 로고    scopus 로고
    • Belimumab shows efficacy for lupus in second pivotal trial
    • accessed 2010 Apr 10
    • Health News Daily. Belimumab shows efficacy for lupus in second pivotal trial. http://healthnewsdaily.elsevierbi.com/cs/Satellite?c=Page&cid= 1216099165884 (accessed 2010 Apr 10).
    • Health News Daily
  • 9
    • 78649959611 scopus 로고    scopus 로고
    • GlaxoSmithKline's Whitty plays down impact of US health care reform
    • May 3
    • Davis J. GlaxoSmithKline's Whitty plays down impact of US health care reform. The Pink Sheet. May 3, 2010.
    • (2010) The Pink Sheet
    • Davis, J.1
  • 11
    • 43649094546 scopus 로고    scopus 로고
    • Belimumab: Anti-BLyS human monoclonal antibody, anti-BLyS monoclonal antibody, BmAb, human monoclonal antibody to b-lymphocyte stimulator
    • Belimumab: anti-BLyS human monoclonal antibody, anti-BLyS monoclonal antibody, BmAb, human monoclonal antibody to b-lymphocyte stimulator. Drugs R D 2008;9:197-202.
    • (2008) Drugs R D , vol.9 , pp. 197-202
  • 12
    • 0037668545 scopus 로고    scopus 로고
    • Pathogenesis of systemic lupus erythematosus
    • Mok CC, Lau CS. Pathogenesis of systemic lupus erythematosus. J Clin Pathol 2003;56:481-90.
    • (2003) J Clin Pathol , vol.56 , pp. 481-490
    • Mok, C.C.1    Lau, C.S.2
  • 13
    • 76349107593 scopus 로고    scopus 로고
    • Pathogenesis of human systemic lupus erythematosus: Recent advances
    • Crispin JC, Liossis S-NC, Kis-Toth K, et al. Pathogenesis of human systemic lupus erythematosus: recent advances. Trends Molec Med 2010; 16:47-57.
    • Trends Molec Med , vol.2010 , Issue.16 , pp. 47-57
    • Crispin, J.C.1    Liossis, S.-N.C.2    Kis-Toth, K.3
  • 14
    • 0021885638 scopus 로고
    • Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives
    • Isenberg DA, Shoenfeld Y, Walport M, et al. Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives. Arthritis Rheum 1985;28:999-1007.
    • (1985) Arthritis Rheum , vol.28 , pp. 999-1007
    • Isenberg, D.A.1    Shoenfeld, Y.2    Walport, M.3
  • 15
    • 40049093765 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Rahman A, Isenberg DA. Systemic lupus erythematosus. N Engl J Med 2008;358:929-39.
    • (2008) N Engl J Med , vol.358 , pp. 929-939
    • Rahman, A.1    Isenberg, D.A.2
  • 16
    • 0033538468 scopus 로고    scopus 로고
    • BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator
    • Moore PA, Belvedere O, Orr A, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999;285:260-3.
    • (1999) Science , vol.285 , pp. 260-263
    • Moore, P.A.1    Belvedere, O.2    Orr, A.3
  • 17
    • 54349100000 scopus 로고    scopus 로고
    • Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BlyS) monoclonal antibody: A phase I trial in patients with systemic lupus erythematosus
    • DOI 10.1186/ar2606
    • Furie R, Stohl W, Ginzler EM, et al. Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BlyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther 2008;10:R109. DOI 10.1186/ar2606
    • (2008) Arthritis Res Ther , vol.10
    • Furie, R.1    Stohl, W.2    Ginzler, E.M.3
  • 18
    • 0035797908 scopus 로고    scopus 로고
    • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
    • Brady JR, Chan B, Lee WP, et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol 2001;11:1547-52.
    • (2001) Curr Biol , vol.11 , pp. 1547-1552
    • Brady, J.R.1    Chan, B.2    Lee, W.P.3
  • 19
    • 0034596831 scopus 로고    scopus 로고
    • Attenuation of apoptosis underlies B lymphocyte stimulation enhancement of humoral immune response
    • Do RK, Hatada E, Lee H, Tourigny MR, Hilbert D, Chen-Kiang S. Attenuation of apoptosis underlies B lymphocyte stimulation enhancement of humoral immune response. J Exp Med 2000;102:953-64.
    • (2000) J Exp Med , vol.102 , pp. 953-964
    • Do, R.K.1    Hatada, E.2    Lee, H.3    Tourigny, M.R.4    Hilbert, D.5    Chen-Kiang, S.6
  • 20
    • 0035167632 scopus 로고    scopus 로고
    • Role for B lymphocyte stimulator in systemic lupus erythematosus
    • Zhang J, Roschke V, Baker KP, et al. Role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 2001;166:6-10.
    • (2001) J Immunol , vol.166 , pp. 6-10
    • Zhang, J.1    Roschke, V.2    Baker, K.P.3
  • 21
    • 0034972257 scopus 로고    scopus 로고
    • Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
    • Cheema GS, Roschke V, Hilbert DM, Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 2001;44:1313-9.
    • (2001) Arthritis Rheum , vol.44 , pp. 1313-1319
    • Cheema, G.S.1    Roschke, V.2    Hilbert, D.M.3    Stohl, W.4
  • 22
    • 10744224617 scopus 로고    scopus 로고
    • B lymphocyte stimulator over-expression in patients with systemic lupus erythematosus
    • Stohl W, Metyas S, Tan SM, et al. B lymphocyte stimulator over-expression in patients with systemic lupus erythematosus. Arthritis Rheum 2003;48:3475-86.
    • (2003) Arthritis Rheum , vol.48 , pp. 3475-3486
    • Stohl, W.1    Metyas, S.2    Tan, S.M.3
  • 23
    • 0242495115 scopus 로고    scopus 로고
    • Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator
    • Baker KP, Edwards BM, Main SH, et al. Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator. Arthritis Rheum 2003;48:3253-65.
    • (2003) Arthritis Rheum , vol.48 , pp. 3253-3265
    • Baker, K.P.1    Edwards, B.M.2    Main, S.H.3
  • 24
    • 0032752441 scopus 로고    scopus 로고
    • Classification and definition of major flares in SLE clinical trials
    • Petri M, Buyon J, Kim M. Classification and definition of major flares in SLE clinical trials. Lupus 1999;8:685-91.
    • (1999) Lupus , vol.8 , pp. 685-691
    • Petri, M.1    Buyon, J.2    Kim, M.3
  • 26
    • 85097570551 scopus 로고    scopus 로고
    • From BILAG to BLIPS - Disease activity assessment in lupus past, present, and future
    • Isenberg DA, Gordon C. From BILAG to BLIPS - disease activity assessment in lupus past, present, and future. Lupus 2000;9:1961-2033.
    • (2000) Lupus , vol.9 , pp. 1961-2033
    • Isenberg, D.A.1    Gordon, C.2
  • 27
    • 69749120918 scopus 로고    scopus 로고
    • A phase II, randomized, double- Blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus
    • Wallace DJ, Stohl W, Furie RA, Lisse JR. A phase II, randomized, double- blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus. Arthritis Rheum 2009; 61:1168-78.
    • (2009) Arthritis Rheum , vol.61 , pp. 1168-1178
    • Wallace, D.J.1    Stohl, W.2    Furie, R.A.3    Lisse, J.R.4
  • 28
    • 74849122596 scopus 로고    scopus 로고
    • Effect of long term belimumab treatment on B cells in systemic lupus erythematosus
    • Jacobi AM, Huang W, Wang T. Effect of long term belimumab treatment on B cells in systemic lupus erythematosus. Arthritis Rheum 2010;62: 201-10.
    • Arthritis Rheum , vol.2010 , Issue.62 , pp. 201-210
    • Jacobi, A.M.1    Huang, W.2    Wang, T.3
  • 32
    • 78649958105 scopus 로고    scopus 로고
    • Belimumab, a BLyS-specific inhibitor, reduces disease activity and severe flares in seropositive SLE patients: BLISS-76 study
    • van Vollenhoven RF, Zamani O, Wallace DJ, et al. Belimumab, a BLyS-specific inhibitor, reduces disease activity and severe flares in seropositive SLE patients: BLISS-76 study. Ann Rheum Dis 2010;69(suppl l3):74.
    • (2010) Ann Rheum Dis , Issue.69 SUPPL. 13 , pp. 74
    • Van Vollenhoven, R.F.1    Zamani, O.2    Wallace, D.J.3
  • 33
    • 78649949609 scopus 로고    scopus 로고
    • accessed 2010 Jun 5
    • Human Genome Sciences Inc.: Benlysta (belimumab). http://www.hgsi. com/belimumab.html (accessed 2010 Jun 5).
    • Benlysta (Belimumab)
  • 36
    • 78649933126 scopus 로고    scopus 로고
    • accessed 2010 Apr 1
    • Lupus Foundation of America. Statistics on Lupus. www.lupus.org/ webmodules/webarticlesnet/templates/new-newsroomreporters.aspx? articleid=247&zoneid=60 (accessed 2010 Apr 1).
    • Statistics on Lupus
  • 37
    • 84860877614 scopus 로고    scopus 로고
    • Market snapshot: After Benlysta breakthrough, how high the sky in lupus?
    • October 13, accessed 2010 May 25
    • Market snapshot: after Benlysta breakthrough, how high the sky in lupus? BioPharmaToday. October 13, 2009. www.biopharmatoday.com/2009/ 10 (accessed 2010 May 25).
    • (2009) BioPharmaToday


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.