메뉴 건너뛰기




Volumn 157, Issue 4, 1996, Pages 1758-1772

Inhibition of Superantigen-Induced Proinflammatory Cytokine Production and Inflammatory Arthritis in MRL-Ipr/Ipr Mice by a Transcriptional Inhibitor of TNF-α

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; CYTOKINE; ENTEROTOXIN; ENTEROTOXIN B, STAPHYLOCOCCAL; FAS ANTIGEN; HLA ANTIGEN CLASS 2; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY; SUPERANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030586573     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (78)

References (97)
  • 2
    • 0024201757 scopus 로고
    • The MRL-lpr/lpr mouse: A model for the study of rheumatoid arthritis
    • Koopman, W. J., and S. Gay. 1988. The MRL-lpr/lpr mouse: a model for the study of rheumatoid arthritis. Scand. J. Rheumatol. 75 (Suppl. 1):284.
    • (1988) Scand. J. Rheumatol. , vol.75 , Issue.1 SUPPL. , pp. 284
    • Koopman, W.J.1    Gay, S.2
  • 3
    • 0025875259 scopus 로고
    • Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen, P. L., and R. A. Eisenberg. 1991. lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9:243.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 243
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 5
    • 0029917320 scopus 로고    scopus 로고
    • Recent advances in the pathogenesis of reactive arthritis
    • Sieper, J., and G. H. Kingsley. 1996. Recent advances in the pathogenesis of reactive arthritis. Immunol. Today 17:160.
    • (1996) Immunol. Today , vol.17 , pp. 160
    • Sieper, J.1    Kingsley, G.H.2
  • 7
    • 0028267767 scopus 로고
    • Clonal expansion of T-lymphocytes causes arthritis and mortality in mice infected with toxic shock syndrome toxin-1 producing staphylococci
    • Abdelnour, A., T. Bremell, R. Holmdahl, and A. Tarkowski. 1994. Clonal expansion of T-lymphocytes causes arthritis and mortality in mice infected with toxic shock syndrome toxin-1 producing staphylococci. Eur. J. Immunol. 24: 1161.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1161
    • Abdelnour, A.1    Bremell, T.2    Holmdahl, R.3    Tarkowski, A.4
  • 9
    • 0027450166 scopus 로고
    • Microbial superantigens as etiopathogenic agents in autoimmunity
    • Friedman, S. M., J. R. Tumang, and M. K. Crow. 1993. Microbial superantigens as etiopathogenic agents in autoimmunity. Rheum. Dis. Clin. North Am. 19:207.
    • (1993) Rheum. Dis. Clin. North Am. , vol.19 , pp. 207
    • Friedman, S.M.1    Tumang, J.R.2    Crow, M.K.3
  • 10
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in fas antigen that mediates apoptosis
    • Watanabe-Fukunaga, R., C. I. Branna, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in fas antigen that mediates apoptosis. Nature 356:314.
    • (1992) Nature , vol.356 , pp. 314
    • Watanabe-Fukunaga, R.1    Branna, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 11
    • 0028927607 scopus 로고
    • The fax death factor
    • Nagata, S., and P. Golstein. 1995. The fax death factor. Science 267:1449.
    • (1995) Science , vol.267 , pp. 1449
    • Nagata, S.1    Golstein, P.2
  • 12
    • 0028888832 scopus 로고
    • Characterization of human fas gene: Exon/intron organization and promoter region
    • Cheng, J., C. Liu, W. J. Koopman, and J. D. Mountz. 1995. Characterization of human fas gene: exon/intron organization and promoter region. J. Immunol. 154: 1239.
    • (1995) J. Immunol. , vol.154 , pp. 1239
    • Cheng, J.1    Liu, C.2    Koopman, W.J.3    Mountz, J.D.4
  • 13
    • 0027245048 scopus 로고
    • Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene
    • Wu, J., T. Zhou, J. He, and J. D. Mountz. 1993. Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene. J. Exp. Med. 178:461.
    • (1993) J. Exp. Med. , vol.178 , pp. 461
    • Wu, J.1    Zhou, T.2    He, J.3    Mountz, J.D.4
  • 14
    • 0028206729 scopus 로고
    • Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice
    • Wu, J., T. Zhou, J. Zhang, J. He, W. C. Gause, and J. D. Mountz. 1994. Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice. Proc. Natl. Acad. Sci. USA 91:2344.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2344
    • Wu, J.1    Zhou, T.2    Zhang, J.3    He, J.4    Gause, W.C.5    Mountz, J.D.6
  • 16
    • 0028835801 scopus 로고
    • Apoptosis: Death of a T cell
    • Strasser, A. 1995. Apoptosis: death of a T cell. Nature 373:385.
    • (1995) Nature , vol.373 , pp. 385
    • Strasser, A.1
  • 17
    • 0028036918 scopus 로고
    • Autoimmune disease: A problem of defective apoptosis
    • Mountz, J. D., J. Wu, J. Cheng, and T. Zhou. 1994. Autoimmune disease: a problem of defective apoptosis. Arthritis Rheum. 10:1415.
    • (1994) Arthritis Rheum. , vol.10 , pp. 1415
    • Mountz, J.D.1    Wu, J.2    Cheng, J.3    Zhou, T.4
  • 18
    • 0028928654 scopus 로고
    • Massive up-regulation of the fas ligand in lpr and gld mice: Implications for fas regulation and the graft-versus-host defense like wasting syndrome
    • Chu, J. L., P. Ramos, A. Rosendorff, J. Nikolic-Zugic, E. Lacy, A. Matsuzawa, and K. B. Elkon. 1995. Massive up-regulation of the fas ligand in lpr and gld mice: implications for fas regulation and the graft-versus-host defense like wasting syndrome. J. Exp. Med. 181:393.
    • (1995) J. Exp. Med. , vol.181 , pp. 393
    • Chu, J.L.1    Ramos, P.2    Rosendorff, A.3    Nikolic-Zugic, J.4    Lacy, E.5    Matsuzawa, A.6    Elkon, K.B.7
  • 20
    • 0027964868 scopus 로고
    • Divergent T-cell cytokine patterns in inflammatory arthritis
    • Simon, A. K., E. Seipelt, and J. Sieper. 1994. Divergent T-cell cytokine patterns in inflammatory arthritis. Proc. Natl. Acad. Sci. USA 91:8562.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8562
    • Simon, A.K.1    Seipelt, E.2    Sieper, J.3
  • 22
    • 0027480306 scopus 로고
    • Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal
    • Suzuki, H., K. Yasukama, T. Saito, M. Narazaki, A. Hasegawa, T. Taga, and T. Kishimoto. 1993. Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal. Eur. J. Immunol. 23: 1078.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1078
    • Suzuki, H.1    Yasukama, K.2    Saito, T.3    Narazaki, M.4    Hasegawa, A.5    Taga, T.6    Kishimoto, T.7
  • 24
    • 0019980516 scopus 로고
    • Spontaneous T-cell lymphokine production and enhanced macrophage Ia expression and tumoricidal activity in MRL-lpr mice
    • Lu, C. Y., and E. R. Unanue. 1987. Spontaneous T-cell lymphokine production and enhanced macrophage Ia expression and tumoricidal activity in MRL-lpr mice. Clin. Immunol. Immunopathol. 25:213.
    • (1987) Clin. Immunol. Immunopathol. , vol.25 , pp. 213
    • Lu, C.Y.1    Unanue, E.R.2
  • 25
    • 0027210810 scopus 로고
    • Elevated production of interleukin-6 by hepatic MNC correlates with ICAM-1 expression on the hepatic sinusoidal endothelial cells in autoimmune MRL/lpr mice
    • Ohteki, T., S. Okamoto, M. Nakamura, E. Nemoto, and K. Kumagai. 1993. Elevated production of interleukin-6 by hepatic MNC correlates with ICAM-1 expression on the hepatic sinusoidal endothelial cells in autoimmune MRL/lpr mice. Immunol. Lett. 36:145.
    • (1993) Immunol. Lett. , vol.36 , pp. 145
    • Ohteki, T.1    Okamoto, S.2    Nakamura, M.3    Nemoto, E.4    Kumagai, K.5
  • 26
    • 0025826597 scopus 로고
    • Increased macrophage colony-stimulating factor in neonatal and adult autoimmune MRL-lpr mice
    • Yui, M. A., W. H. Brissette, D. C. Brennan, R. P. Wuthrich, and V. E. Rubin-Kelley. 1991. Increased macrophage colony-stimulating factor in neonatal and adult autoimmune MRL-lpr mice. Am. J. Pathol. 139:255.
    • (1991) Am. J. Pathol. , vol.139 , pp. 255
    • Yui, M.A.1    Brissette, W.H.2    Brennan, D.C.3    Wuthrich, R.P.4    Rubin-Kelley, V.E.5
  • 27
    • 0028304714 scopus 로고
    • Immune complex-degradation ability of macrophages in MRL-Mp-lpr/lpr lupus mice and its regulation by cytokines
    • Kanno, H., O. Tachiwaki, M. Nose, and M. Kyogoku. 1994. Immune complex-degradation ability of macrophages in MRL-Mp-lpr/lpr lupus mice and its regulation by cytokines. Clin. Exp. Immunol. 95:115.
    • (1994) Clin. Exp. Immunol. , vol.95 , pp. 115
    • Kanno, H.1    Tachiwaki, O.2    Nose, M.3    Kyogoku, M.4
  • 28
    • 0028145440 scopus 로고
    • Effect of aging on murine macrophages: Diminished response to IFN-γ for enhanced oxidative metabolism
    • Ding, A., S. Hwang, and R. Schwab. 1994. Effect of aging on murine macrophages: diminished response to IFN-γ for enhanced oxidative metabolism. J. Immunol. 153:2146.
    • (1994) J. Immunol. , vol.153 , pp. 2146
    • Ding, A.1    Hwang, S.2    Schwab, R.3
  • 29
    • 0023732974 scopus 로고
    • Increased tumor necrosis factor and IL-1β nephritis
    • Boswell, J. M., M. A. Yui, D. W. Burt, and V. E. Kelley. 1988. Increased tumor necrosis factor and IL-1β nephritis. J. Immunol. 141:3050.
    • (1988) J. Immunol. , vol.141 , pp. 3050
    • Boswell, J.M.1    Yui, M.A.2    Burt, D.W.3    Kelley, V.E.4
  • 31
    • 0025905168 scopus 로고
    • In vivo effects of interleukin-1 on articular cartilage: Prolongation of proteoglycan metabolic disturbances in old mice
    • Van Beuningen, H. M., I. J. Arntz, and W. B. van den Berg. 1991. In vivo effects of interleukin-1 on articular cartilage: prolongation of proteoglycan metabolic disturbances in old mice. Arthritis Rheum. 34:606.
    • (1991) Arthritis Rheum. , vol.34 , pp. 606
    • Van Beuningen, H.M.1    Arntz, I.J.2    Van Den Berg, W.B.3
  • 32
    • 0025891275 scopus 로고
    • Involvement of macrophages and dendritic cells in synovial inflammation of collagen induced arthritis in DBA/1 mice and spontaneous arthritis in MRL/lpr mice
    • Holmdahl, R., A. Tarkowsi, and R. Jonsson. 1991. Involvement of macrophages and dendritic cells in synovial inflammation of collagen induced arthritis in DBA/1 mice and spontaneous arthritis in MRL/lpr mice. Autoimmunity 8:271.
    • (1991) Autoimmunity , vol.8 , pp. 271
    • Holmdahl, R.1    Tarkowsi, A.2    Jonsson, R.3
  • 33
    • 0024511891 scopus 로고
    • The abnormal T lymphocytes in lpr mice transcribe interferon-γ and tumor necrosis factor-α genes spontaneously in vivo
    • Murray, L., and C. Martens. 1989. The abnormal T lymphocytes in lpr mice transcribe interferon-γ and tumor necrosis factor-α genes spontaneously in vivo. Eur. J. Immunol. 19:563.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 563
    • Murray, L.1    Martens, C.2
  • 34
    • 0028345668 scopus 로고
    • In vivo cytokine gene expression in various T cell subsets of the autoimmune MRL/Mp-lpr/lpr mouse
    • Mori, K., S. Kobayashi, M. Inobe, W.-Y. Jia, M. Tamakoshi, T. Miyazaki, and T. Uede. 1994. In vivo cytokine gene expression in various T cell subsets of the autoimmune MRL/Mp-lpr/lpr mouse. Autoimmunity 17:49.
    • (1994) Autoimmunity , vol.17 , pp. 49
    • Mori, K.1    Kobayashi, S.2    Inobe, M.3    Jia, W.-Y.4    Tamakoshi, M.5    Miyazaki, T.6    Uede, T.7
  • 35
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand
    • Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand. Cell 76:969.
    • (1994) Cell , vol.76 , pp. 969
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 36
    • 0028353492 scopus 로고
    • The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
    • Smith, C. A., T. Farrah, and R. G. Goodwin. 1994. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76:959.
    • (1994) Cell , vol.76 , pp. 959
    • Smith, C.A.1    Farrah, T.2    Goodwin, R.G.3
  • 39
    • 0029063510 scopus 로고
    • Specific transcriptional inhibition of bone-marrow-derived macrophage (BMDMφ) TNF-α gene expression and protein production using novel enantiomeric carbocyclic nucleoside analogues
    • Bradshaw, M., M. Rutherford, L. B. Schook, D. R. Borcherding, C. D. McWhinney, B. J. Hoeper, and C. K. Edwards III. 1995. Specific transcriptional inhibition of bone-marrow-derived macrophage (BMDMφ) TNF-α gene expression and protein production using novel enantiomeric carbocyclic nucleoside analogues. J. Pharmacol. Exp. Ther. 273:1506.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 1506
    • Bradshaw, M.1    Rutherford, M.2    Schook, L.B.3    Borcherding, D.R.4    McWhinney, C.D.5    Hoeper, B.J.6    Edwards III, C.K.7
  • 40
    • 0028972554 scopus 로고
    • Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock
    • Mountz, J. D., T. J. Baker, D. R. Borcherding, H. Bluethmann, T. Zhou, and C. K. Edwards III. 1995. Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock. J. Immunol. 155:4829.
    • (1995) J. Immunol. , vol.155 , pp. 4829
    • Mountz, J.D.1    Baker, T.J.2    Borcherding, D.R.3    Bluethmann, H.4    Zhou, T.5    Edwards III, C.K.6
  • 41
    • 0029093807 scopus 로고
    • Differential expression of human fas mRNA species upon peripheral blood mononuclear cell activation
    • Liu, C., J. Cheng, and J. D. Mountz. 1995. Differential expression of human fas mRNA species upon peripheral blood mononuclear cell activation. Biochem. J. 31:957.
    • (1995) Biochem. J. , vol.31 , pp. 957
    • Liu, C.1    Cheng, J.2    Mountz, J.D.3
  • 44
    • 0028092366 scopus 로고
    • Apoptosis defect analyzed in TCR transgenic and for transgenic lpr mice
    • Mountz, J. D., T. Zhou, H. Bluethmann, J. Wu, and C. K. Edwards III. 1994. Apoptosis defect analyzed in TCR transgenic and for transgenic lpr mice. Int. Immunol. 11:321.
    • (1994) Int. Immunol. , vol.11 , pp. 321
    • Mountz, J.D.1    Zhou, T.2    Bluethmann, H.3    Wu, J.4    Edwards III, C.K.5
  • 45
    • 0026802409 scopus 로고
    • Murine models of autoimmunity: T cell and B cell defects
    • Mountz, J. D., and C. K. Edwards III. 1992. Murine models of autoimmunity: T cell and B cell defects. Curr. Opin. Rheumatol. 4:612.
    • (1992) Curr. Opin. Rheumatol. , vol.4 , pp. 612
    • Mountz, J.D.1    Edwards III, C.K.2
  • 47
    • 0026471742 scopus 로고
    • Genetic analysis of MRL-lpr/lpr mice: Relationship of the fas apoptosis gene to disease manifestations and renal disease-modifying loci
    • Watson, M. L., J. K. Rao, G. S. Gilkeson, P. Ruiz, E. M. Eicher, D. S. Pisetsky, A. Matsuzawa, J. M. Rochell, and M. F. Seldin. 1992. Genetic analysis of MRL-lpr/lpr mice: relationship of the fas apoptosis gene to disease manifestations and renal disease-modifying loci. J. Exp. Med. 176:1645.
    • (1992) J. Exp. Med. , vol.176 , pp. 1645
    • Watson, M.L.1    Rao, J.K.2    Gilkeson, G.S.3    Ruiz, P.4    Eicher, E.M.5    Pisetsky, D.S.6    Matsuzawa, A.7    Rochell, J.M.8    Seldin, M.F.9
  • 49
    • 0025836814 scopus 로고
    • Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment
    • Kim, C., K. A. Siminovitch, and A. Ochi. 1991. Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment. J. Exp. Med. 174:1431.
    • (1991) J. Exp. Med. , vol.174 , pp. 1431
    • Kim, C.1    Siminovitch, K.A.2    Ochi, A.3
  • 51
    • 0026671268 scopus 로고
    • Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice
    • Zhou, T., H. Bluethmann, J. Zhang, C. K. Edwards III, and J. D. Mountz. 1992. Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice. J. Exp. Med. 176:1063.
    • (1992) J. Exp. Med. , vol.176 , pp. 1063
    • Zhou, T.1    Bluethmann, H.2    Zhang, J.3    Edwards III, C.K.4    Mountz, J.D.5
  • 52
    • 0028324486 scopus 로고
    • T cells of staphylococcal enterotoxin B tolerized autoimmune MRL-lpr/lpr mice require costimulation through the B7-CD28/CTLA-4 pathway for activation and can be reanergized in vivo by stimulation of the TCR in the absence of this costimulatory signal
    • Zhou, T., C. Weaver, P. S. Linsley, and J. D. Mountz. 1994. T cells of staphylococcal enterotoxin B tolerized autoimmune MRL-lpr/lpr mice require costimulation through the B7-CD28/CTLA-4 pathway for activation and can be reanergized in vivo by stimulation of the TCR in the absence of this costimulatory signal. Eur. J. Immunol. 24:1019.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1019
    • Zhou, T.1    Weaver, C.2    Linsley, P.S.3    Mountz, J.D.4
  • 53
    • 85081470198 scopus 로고
    • Elevated proinflammatory cytokine production by macrophages obtained from MRL-lpr/lpr autoimmune mice correlates to defective fas antigen gene expression
    • Abstr.
    • Edwards, C. K., III, T. Zhou, J. Zhang, C. D. McWhinney, T. L. Bowlin, and J. D. Mountz. 1993. Elevated proinflammatory cytokine production by macrophages obtained from MRL-lpr/lpr autoimmune mice correlates to defective fas antigen gene expression. Arthritis Rheum. 36:561 (Abstr.).
    • (1993) Arthritis Rheum. , vol.36 , pp. 561
    • Edwards III, C.K.1    Zhou, T.2    Zhang, J.3    McWhinney, C.D.4    Bowlin, T.L.5    Mountz, J.D.6
  • 54
    • 0026530973 scopus 로고
    • Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes
    • Mourad, W., K. Mehindate, T. J. Schall, and S. R. McColl. 1992. Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes. J. Exp. Med. 175:613.
    • (1992) J. Exp. Med. , vol.175 , pp. 613
    • Mourad, W.1    Mehindate, K.2    Schall, T.J.3    McColl, S.R.4
  • 55
    • 0030584786 scopus 로고    scopus 로고
    • Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor I
    • Zhou, T., C. K. Edwards III, P. Yang, Z. Wang, H. Bluethmann, and J. D. Mountz. 1996. Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor I. J. Immunol. 156:2661.
    • (1996) J. Immunol. , vol.156 , pp. 2661
    • Zhou, T.1    Edwards III, C.K.2    Yang, P.3    Wang, Z.4    Bluethmann, H.5    Mountz, J.D.6
  • 56
    • 0026741058 scopus 로고
    • Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-Vβ8 antibodies
    • De Alboran, I. M., J. A. Gonzalo, G. Kroemer, E. Leonardo, M. A. R. Marcos, and C. Martinez-A. 1992. Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-Vβ8 antibodies. Eur. J. Immunol. 22:2153.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2153
    • De Alboran, I.M.1    Gonzalo, J.A.2    Kroemer, G.3    Leonardo, E.4    Marcos, M.A.R.5    Martinez-A, C.6
  • 57
    • 85081470397 scopus 로고    scopus 로고
    • A fas antigen receptor mutation allows development of toxic shock syndrome toxin-1-induced lethal shock in Vβ8.2 T-cell receptor transgenic mice
    • In press
    • Cullen, C. M., P. F. Bonventre, H. Heeg, H. Bluethmann, J. D. Mountz, and C. K. Edwards III. 1996. A fas antigen receptor mutation allows development of toxic shock syndrome toxin-1-induced lethal shock in Vβ8.2 T-cell receptor transgenic mice. Pathobiology. In press.
    • (1996) Pathobiology
    • Cullen, C.M.1    Bonventre, P.F.2    Heeg, H.3    Bluethmann, H.4    Mountz, J.D.5    Edwards III, C.K.6
  • 58
    • 0025070203 scopus 로고
    • The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells
    • Marrack, P., M. Blackman, E. Kushnir, and S. Kappler. 1990. The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J. Exp. Med. 171: 445.
    • (1990) J. Exp. Med. , vol.171 , pp. 445
    • Marrack, P.1    Blackman, M.2    Kushnir, E.3    Kappler, S.4
  • 59
    • 0029061537 scopus 로고
    • Prevention of age-related T cell apoptosis defect in CD2-fas transgenic mice
    • Zhou, T., C. K. Edwards III, and J. D. Mountz. 1995. Prevention of age-related T cell apoptosis defect in CD2-fas transgenic mice. J. Exp. Med. 182:129.
    • (1995) J. Exp. Med. , vol.182 , pp. 129
    • Zhou, T.1    Edwards III, C.K.2    Mountz, J.D.3
  • 60
    • 0028889990 scopus 로고
    • Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice
    • Reap, E. A., D. Leslie, M. Abrams, R. A. Eisenberg, and P. L. Cohen. 1995. Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice. J. Immunol. 154:956.
    • (1995) J. Immunol. , vol.154 , pp. 956
    • Reap, E.A.1    Leslie, D.2    Abrams, M.3    Eisenberg, R.A.4    Cohen, P.L.5
  • 61
    • 85038068645 scopus 로고    scopus 로고
    • fas and tumor necrosis factor-receptor I-mediated activation-induced cell death of macrophages
    • Zhou, T., C. K. Edwards III, H. Bluethmann, and J. D. Mountz. 1996. fas and tumor necrosis factor-receptor I-mediated activation-induced cell death of macrophages. FASEB J. 9:A352.
    • (1996) FASEB J. , vol.9
    • Zhou, T.1    Edwards III, C.K.2    Bluethmann, H.3    Mountz, J.D.4
  • 63
    • 0028061681 scopus 로고
    • Modulation of Mycoplosma arthritidis-derived superantigen-induced cytokine gene expression by dexamethasone and interleukin-4
    • Mehindate, K., R. Al-Daacak, L. Ricels, S. Mecheri, J. Hebert, and W. Mourad. 1994. Modulation of Mycoplosma arthritidis-derived superantigen-induced cytokine gene expression by dexamethasone and interleukin-4. Infect. Immun. 62: 4716.
    • (1994) Infect. Immun. , vol.62 , pp. 4716
    • Mehindate, K.1    Al-Daacak, R.2    Ricels, L.3    Mecheri, S.4    Hebert, J.5    Mourad, W.6
  • 65
    • 0027266844 scopus 로고
    • Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice
    • Scott, D. E., W. J. Kisch, and A. D. Steinberg. 1993. Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice. J. Immunol. 150:664.
    • (1993) J. Immunol. , vol.150 , pp. 664
    • Scott, D.E.1    Kisch, W.J.2    Steinberg, A.D.3
  • 66
    • 0025096424 scopus 로고
    • + T cells in staphylococcus enterotoxin B-primed mice
    • + T cells in staphylococcus enterotoxin B-primed mice. J. Exp. Med. 172:1065.
    • (1990) J. Exp. Med. , vol.172 , pp. 1065
    • Kawabe, Y.1    Ochi, A.2
  • 67
    • 0027270126 scopus 로고
    • Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen
    • McCormack, J. E., J. E. Callahan, J. Kappler, and P. C. Marrack. 1993. Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen. J. Immunol. 150:3785.
    • (1993) J. Immunol. , vol.150 , pp. 3785
    • McCormack, J.E.1    Callahan, J.E.2    Kappler, J.3    Marrack, P.C.4
  • 69
    • 0027969274 scopus 로고
    • Macrophages are dispensible for superantigen-mediated stimulation and anergy induction of peripheral T cells in vivo
    • Koesling, M., O. Rott, and B. Fleischer. 1994. Macrophages are dispensible for superantigen-mediated stimulation and anergy induction of peripheral T cells in vivo. Cell. Immunol. 157:29.
    • (1994) Cell. Immunol. , vol.157 , pp. 29
    • Koesling, M.1    Rott, O.2    Fleischer, B.3
  • 70
    • 0028213094 scopus 로고
    • Differentiated in vivo effects of a superantigen and an antibody targeted to the same T cell receptor: Activation-induced cell death vs passive macrophage-dependent depletion
    • Gonzalo, J. A., E. Baixeras, A. Gonzalez-Garcia, A. George-Chandy, N. V. Rooijen, C. Martinez-A., and G. Kroemer. 1994. Differentiated in vivo effects of a superantigen and an antibody targeted to the same T cell receptor: activation-induced cell death vs passive macrophage-dependent depletion. J. Immunol. 152: 1597.
    • (1994) J. Immunol. , vol.152 , pp. 1597
    • Gonzalo, J.A.1    Baixeras, E.2    Gonzalez-Garcia, A.3    George-Chandy, A.4    Rooijen, N.V.5    Martinez-A, C.6    Kroemer, G.7
  • 71
    • 0027547296 scopus 로고
    • Not every superantigen induces tolerance in vivo
    • Ochi, A., K. Yuh, and K. Migita. 1993. Not every superantigen induces tolerance in vivo. Semin. Immunol. 5:57.
    • (1993) Semin. Immunol. , vol.5 , pp. 57
    • Ochi, A.1    Yuh, K.2    Migita, K.3
  • 72
    • 0029671297 scopus 로고    scopus 로고
    • In vivo blockade of TNF-α by intravenous infusion of a chimeric monoclonal TNF-α antibody in patients with rheumatoid arthritis: Short term cellular and molecular effects
    • Lorenz, H. M., C. Antoni, T. Valerius, R. Repp, M. Grunke, N. Schwerdtner, H. Nusslein, J. Woody, J. R. Kalden, and B. Manger. 1996. In vivo blockade of TNF-α by intravenous infusion of a chimeric monoclonal TNF-α antibody in patients with rheumatoid arthritis: short term cellular and molecular effects. J. Immunol. 156:1646.
    • (1996) J. Immunol. , vol.156 , pp. 1646
    • Lorenz, H.M.1    Antoni, C.2    Valerius, T.3    Repp, R.4    Grunke, M.5    Schwerdtner, N.6    Nusslein, H.7    Woody, J.8    Kalden, J.R.9    Manger, B.10
  • 73
    • 0028122043 scopus 로고
    • Properties and functions of interleukin-10
    • Mossman, T. R. 1994. Properties and functions of interleukin-10. Adv. Immunol. 56:1.
    • (1994) Adv. Immunol. , vol.56 , pp. 1
    • Mossman, T.R.1
  • 76
    • 0026741058 scopus 로고
    • Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-Vβ8.2 antibodies
    • de Alboran, I. M., J. A. Gonzalo, G. Kroemer, E. Leonardo, M. A. R. Marcos, and C. Martinez-A. 1992. Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-Vβ8.2 antibodies. Eur. J. Immunol. 22:2153.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2153
    • De Alboran, I.M.1    Gonzalo, J.A.2    Kroemer, G.3    Leonardo, E.4    Marcos, M.A.R.5    Martinez-A, C.6
  • 77
    • 85081464844 scopus 로고
    • Use of disease-modifying agents to elucidate pathogenic mechanisms in superantigen-induced arthritis in Vβ8.2 T cell receptor transgenic MRL-lpr/lpr mice
    • Abstr.
    • Edwards, C. K., III, T. Zhou, J. Zhang, R. E. Long, D. R. Borcherding, and J. D. Mountz. 1992. Use of disease-modifying agents to elucidate pathogenic mechanisms in superantigen-induced arthritis in Vβ8.2 T cell receptor transgenic MRL-lpr/lpr mice. J. Cell. Biochem. 16:46 (Abstr.).
    • (1992) J. Cell. Biochem. , vol.16 , pp. 46
    • Edwards III, C.K.1    Zhou, T.2    Zhang, J.3    Long, R.E.4    Borcherding, D.R.5    Mountz, J.D.6
  • 78
    • 0029094780 scopus 로고
    • Biased T cell receptor Vβ gene usage during specific stages of the development of autoimmune sialadenitis in the MRL/lpr mouse model of Sjogrens syndrome
    • Hayashi, Y., H. Hamano, N. Haneji, N. Ishimaru, and K. Yanagi. 1995. Biased T cell receptor Vβ gene usage during specific stages of the development of autoimmune sialadenitis in the MRL/lpr mouse model of Sjogrens syndrome. Arthritis Rheum. 38:1077.
    • (1995) Arthritis Rheum. , vol.38 , pp. 1077
    • Hayashi, Y.1    Hamano, H.2    Haneji, N.3    Ishimaru, N.4    Yanagi, K.5
  • 79
    • 0027157295 scopus 로고
    • Superantigens can reactivate bacterial cell wall-induced arthritis
    • Schwab, J. H., R. R. Brown, S. K. Anderle, and P. M. Schlievert. 1993. Superantigens can reactivate bacterial cell wall-induced arthritis. J. Immunol. 150: 4151.
    • (1993) J. Immunol. , vol.150 , pp. 4151
    • Schwab, J.H.1    Brown, R.R.2    Anderle, S.K.3    Schlievert, P.M.4
  • 80
    • 0027308742 scopus 로고
    • The fate of anergic T cells in vivo
    • Migita, K., and A. Ochi. 1993. The fate of anergic T cells in vivo. J. Immunol. 150:763.
    • (1993) J. Immunol. , vol.150 , pp. 763
    • Migita, K.1    Ochi, A.2
  • 81
    • 0025776169 scopus 로고
    • Expansion and high proliferative potential of the macrophage system throughout life time of lupus-prone NZB/W and MRL-lpr/lpr mice: Lack of down-regulation of extramedullar macrophage proliferation in the postnatal period
    • Muller, M., A. Emmendorffer, and M. L. Lohman-Matthes. 1991. Expansion and high proliferative potential of the macrophage system throughout life time of lupus-prone NZB/W and MRL-lpr/lpr mice: lack of down-regulation of extramedullar macrophage proliferation in the postnatal period. Eur. J. Immunol. 21:2211.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2211
    • Muller, M.1    Emmendorffer, A.2    Lohman-Matthes, M.L.3
  • 82
    • 0027418037 scopus 로고
    • Expansion of the liver-associated macrophage system in systemic lupus erythematosus-prone NZB/W mice
    • Emmendorffer, A., M. Muller, D. Wedekind, K. Hartung, and M. L. Lohman-Mathes. 1993. Expansion of the liver-associated macrophage system in systemic lupus erythematosus-prone NZB/W mice. J. Leukocyte Biol. 53:294.
    • (1993) J. Leukocyte Biol. , vol.53 , pp. 294
    • Emmendorffer, A.1    Muller, M.2    Wedekind, D.3    Hartung, K.4    Lohman-Mathes, M.L.5
  • 83
    • 0028941699 scopus 로고
    • Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks fas-mediated apoptosis
    • Su, X., T. Zhou, C. Liu, J. P. Shapiro, M. J. Brauer, M. C. Kiefer, P. J. Barr, and J. D. Mountz. 1994. Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks fas-mediated apoptosis. Immunity 2:353.
    • (1994) Immunity , vol.2 , pp. 353
    • Su, X.1    Zhou, T.2    Liu, C.3    Shapiro, J.P.4    Brauer, M.J.5    Kiefer, M.C.6    Barr, P.J.7    Mountz, J.D.8
  • 84
    • 0028955622 scopus 로고
    • Activation-induced apoptosis in human macrophages: Developmental regulation of a novel cell death pathway by macrophage colony stimulating factors and interferon-γ
    • Munn, D. H., A. C. Beale, D. Sarg, R. W. Wrenn, and D. C. Throckmorton. 1995. Activation-induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony stimulating factors and interferon-γ. J. Exp. Med. 181:127.
    • (1995) J. Exp. Med. , vol.181 , pp. 127
    • Munn, D.H.1    Beale, A.C.2    Sarg, D.3    Wrenn, R.W.4    Throckmorton, D.C.5
  • 85
    • 0027219772 scopus 로고
    • Transcriptional repression and differential splicing of fas mRNA by early transposon (ETn) insertion in autoimmune lpr mice
    • Kobayashi, S., T. Hirano, M. Kakinuma, and T. Uede. 1993. Transcriptional repression and differential splicing of fas mRNA by early transposon (ETn) insertion in autoimmune lpr mice. Biochem. Biophys. Res. Commun. 191:617.
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 617
    • Kobayashi, S.1    Hirano, T.2    Kakinuma, M.3    Uede, T.4
  • 86
    • 0028106942 scopus 로고
    • Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection
    • Reiner, N. E. 1994. Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection. Immunol. Today 15:374.
    • (1994) Immunol. Today , vol.15 , pp. 374
    • Reiner, N.E.1
  • 87
    • 0028223194 scopus 로고
    • Sepsis-induced apoptosis of the thymocytes in mice
    • Wang, S.-D., K.-J. Huang, Y.-S. Lin, and H.-Y. Lei. 1994. Sepsis-induced apoptosis of the thymocytes in mice. J. Immunol. 152:5014.
    • (1994) J. Immunol. , vol.152 , pp. 5014
    • Wang, S.-D.1    Huang, K.-J.2    Lin, Y.-S.3    Lei, H.-Y.4
  • 88
    • 0028049996 scopus 로고
    • Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice
    • Florquin, S., Z. Amraoui, D. Abramowicz, and M. Goldman. 1994. Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice. J. Immunol. 153:2618.
    • (1994) J. Immunol. , vol.153 , pp. 2618
    • Florquin, S.1    Amraoui, Z.2    Abramowicz, D.3    Goldman, M.4
  • 89
    • 0028911482 scopus 로고
    • Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the induction of cytokines by human peripheral blood mononuclear cells: Priming for IL-12 and tumor necrosis factor-α production
    • D'Andréa, A., X. Ma, M. A.-Amezaga, C. Paganin, and G. Trinchieri. 1995. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the induction of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor-α production. J. Exp. Med. 181:537.
    • (1995) J. Exp. Med. , vol.181 , pp. 537
    • D'Andréa, A.1    Ma, X.2    A-Amezaga, M.3    Paganin, C.4    Trinchieri, G.5
  • 90
    • 0028020587 scopus 로고
    • Spontaneous elaboration of transforming growth factor β suppresses host defense against bacterial infection in autoimmune MRL/lpr mice
    • Lowrance, J. H., F. X. O'Sullivan, T. E. Caver, W. Waegell, and H. D. Gresham. 1994. Spontaneous elaboration of transforming growth factor β suppresses host defense against bacterial infection in autoimmune MRL/lpr mice. J. Exp. Med. 180:1693.
    • (1994) J. Exp. Med. , vol.180 , pp. 1693
    • Lowrance, J.H.1    O'Sullivan, F.X.2    Caver, T.E.3    Waegell, W.4    Gresham, H.D.5
  • 91
    • 0029928187 scopus 로고    scopus 로고
    • Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice
    • Takahashi, S., L. Fossati, M. Iwamoto, R. Merino, R. Motta, T. Kobayakawa, and S. Izui. 1996. Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. J. Clin. Invest. 97:1597.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1597
    • Takahashi, S.1    Fossati, L.2    Iwamoto, M.3    Merino, R.4    Motta, R.5    Kobayakawa, T.6    Izui, S.7
  • 92
    • 0028861236 scopus 로고
    • Inhibition of the production and effects of interleukin-1 and tumor necrosis factor-α in rheumatoid arthritis
    • Arend, W. P., and J. M. Dayer. 1995. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor-α in rheumatoid arthritis. Arthritis Rheum. 38:151.
    • (1995) Arthritis Rheum. , vol.38 , pp. 151
    • Arend, W.P.1    Dayer, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.