A tolerogenic peptide down-regulates mature B cells in bone marrow of lupus-afflicted mice by inhibition of interleukin-7, leading to apoptosis

Immunology

Volumn 128, Issue 2, 2009, Pages 245-252

  Ben David, Hava ^a   Sharabi, Amir ^a   Parameswaran, Reshmi ^a   Zinger, Heidy ^a   Mozes, Edna ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Bone marrow; IL 7; Mature B cells; Murine lupus; Tolerogenic peptide

Indexed keywords

GAMMA INTERFERON; IMMUNOMODULATING AGENT; INTERLEUKIN 10; INTERLEUKIN 7; PEPTIDE HCDR1; PROTEIN BCL XL; SYNTHETIC PEPTIDE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BONE MARROW; BONE MARROW CELL; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; FEMALE; GENE REPRESSION; IMMUNOMODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; UPREGULATION;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; B-LYMPHOCYTE SUBSETS; BONE MARROW CELLS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; IMMUNE TOLERANCE; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-7; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, INBRED STRAINS; PEPTIDE FRAGMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 69949159382     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03109.x     Document Type: Article

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