Assessment of RTG-W1, RTL-W1, and PLHC-1 fish cell lines for genotoxicity testing of environmental pollutants by means of a Fpg-modified comet assay

Toxicology in Vitro

Volumn 26, Issue 3, 2012, Pages 500-510

  Kienzler, Aude ^a   Tronchère, Xavier ^a   Devaux, Alain ^a   Bony, Sylvie ^a  

^a UNIVERSITÉ DE LYON   (France)

Author keywords

Comet assay; Fish cell line; Formamido pyrimidine glycosylase; Genotoxicity; Pollutant

Indexed keywords

CYTOCHROME P450; ETHOXYRESORUFIN DEETHYLASE; FORMAMIDO PYRIMIDINE GLYCOSYLASE; REAGENT; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL CELL; ARTICLE; CELL LINE; CELL METABOLISM; CELL VIABILITY; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY TEST; DNA ALKYLATION; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; GENOTOXICITY; NONHUMAN; OXIDATIVE STRESS; PLHC 1 CELL LINE; PREDICTION; PROCESS OPTIMIZATION; RTG W1 CELL LINE; RTL W1 CELL LINE; SENSITIVITY AND SPECIFICITY; WATER POLLUTANT;

ANIMALS; CELL LINE; COMET ASSAY; CYPRINODONTIFORMES; DNA DAMAGE; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; MUTAGENS; ONCORHYNCHUS MYKISS; OXIDATIVE STRESS; RISK ASSESSMENT; SPECIES SPECIFICITY;

EID: 84857685084     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.01.001     Document Type: Article

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