메뉴 건너뛰기




Volumn 34, Issue 4, 1999, Pages 246-255

Comet assay in genetic ecotoxicology: A review

Author keywords

Alkaline Comet assay; Genotoxicity; MGE assay; SCGE assay

Indexed keywords

ALKALI;

EID: 0342904908     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1999)34:4<246::AID-EM4>3.0.CO;2-V     Document Type: Review
Times cited : (242)

References (39)
  • 1
    • 0031982721 scopus 로고    scopus 로고
    • The international comet assay workshop
    • Anderson D, Plewa MJ. 1998. The International Comet Assay Workshop. Mutagenesis 13:67-73.
    • (1998) Mutagenesis , vol.13 , pp. 67-73
    • Anderson, D.1    Plewa, M.J.2
  • 2
    • 0028910894 scopus 로고
    • The single cell gel electrophoresis assay for induced DNA damage (comet assay): Measurement of tail length and moment
    • Ashby J, Tinwell H, Lefevre PA, Browne MA. 1995. The single cell gel electrophoresis assay for induced DNA damage (comet assay): measurement of tail length and moment. Mutagenesis 10:85-90.
    • (1995) Mutagenesis , vol.10 , pp. 85-90
    • Ashby, J.1    Tinwell, H.2    Lefevre, P.A.3    Browne, M.A.4
  • 3
    • 0029844440 scopus 로고    scopus 로고
    • Cytogenetic studies of PCB77 on brown trout (Salmo trutta fario) using the micronucleus test and the alkaline comet assay
    • Belpaeme K, Delbeke K, Zhu L, Kirsch-Volders M. 1996. Cytogenetic studies of PCB77 on brown trout (Salmo trutta fario) using the micronucleus test and the alkaline comet assay. Mutagenesis 11: 485-492.
    • (1996) Mutagenesis , vol.11 , pp. 485-492
    • Belpaeme, K.1    Delbeke, K.2    Zhu, L.3    Kirsch-Volders, M.4
  • 4
    • 0032584623 scopus 로고    scopus 로고
    • Development and validation of the in vivo alkaline comet assay for detecting genomic damage in marine flatfish
    • Belpaeme K, Cooreman K, Kirsch-Volders M. 1998. Development and validation of the in vivo alkaline comet assay for detecting genomic damage in marine flatfish. Mutat Res (Genet Toxicol EM) 415:167-184.
    • (1998) Mutat Res (Genet Toxicol EM) , vol.415 , pp. 167-184
    • Belpaeme, K.1    Cooreman, K.2    Kirsch-Volders, M.3
  • 5
    • 0030469053 scopus 로고    scopus 로고
    • The comet assay for the evaluation of the genetic hazard of pollutants in cetaceans: Preliminary results on the genotoxic effects of methyl-mercury on the bottle-nosed dolphin (Tursiops truncatus) lymphocytes in vitro
    • Betti C, Nigro M. 1996. The Comet assay for the evaluation of the genetic hazard of pollutants in cetaceans: preliminary results on the genotoxic effects of methyl-mercury on the bottle-nosed dolphin (Tursiops truncatus) lymphocytes in vitro. Mar Pollut Bull 32:545-548.
    • (1996) Mar Pollut Bull , vol.32 , pp. 545-548
    • Betti, C.1    Nigro, M.2
  • 6
    • 0002712530 scopus 로고
    • Identification of irradiated food by microelectrophoresis of DNA from single cells
    • Leonardi M, Belliardo JJ, Raffi JJ (eds): Recent advances of new methods of detection of irradiated food. Luxembourg: Commission of the European Communities, EUR-14315
    • Cerda H, Hofsten BV, Johanson KJ. 1993. Identification of irradiated food by microelectrophoresis of DNA from single cells. In Leonardi M, Belliardo JJ, Raffi JJ (eds): Recent advances of new methods of detection of irradiated food. Proceedings of the workshop, Ancona, 24-26 September 1991. Luxembourg: Commission of the European Communities, EUR-14315, pp 401-405.
    • (1993) Proceedings of the Workshop, Ancona, 24-26 September 1991 , pp. 401-405
    • Cerda, H.1    Hofsten, B.V.2    Johanson, K.J.3
  • 7
    • 0030995574 scopus 로고    scopus 로고
    • Genotoxicity of select herbicides in Rana catesbeiana tadpoles using the alkaline single-cell gel DNA electrophoresis (comet) assay
    • Clements C, Ralph S, Petras M. 1997. Genotoxicity of select herbicides in Rana catesbeiana tadpoles using the alkaline single-cell gel DNA electrophoresis (comet) assay. Environ Mol Mutagen 29:277-288.
    • (1997) Environ Mol Mutagen , vol.29 , pp. 277-288
    • Clements, C.1    Ralph, S.2    Petras, M.3
  • 8
    • 0030844682 scopus 로고    scopus 로고
    • Nereis virens (Annelida: Polychaeta) is not an adequate sentinel species to assess the genotoxic risk (comet assay) of PAH exposure to the environment
    • De Boeck M, Kirsch-Volders M. 1997. Nereis virens (Annelida: Polychaeta) is not an adequate sentinel species to assess the genotoxic risk (Comet assay) of PAH exposure to the environment. Environ Mol Mutagen 30:82-90.
    • (1997) Environ Mol Mutagen , vol.30 , pp. 82-90
    • De Boeck, M.1    Kirsch-Volders, M.2
  • 9
    • 0031005561 scopus 로고    scopus 로고
    • Alkaline comet assay in rainbow trout hepatocytes
    • Devaux A, Pesonen M, Monod G. 1997. Alkaline comet assay in rainbow trout hepatocytes. Toxicol in Vitro 11:71-79.
    • (1997) Toxicol in Vitro , vol.11 , pp. 71-79
    • Devaux, A.1    Pesonen, M.2    Monod, G.3
  • 10
    • 0032123365 scopus 로고    scopus 로고
    • Monitoring of the chemical pollution of the river Rhone through measurement of DNA damage and cytochrome P4501A induction in chub (Leuciscus cephalus)
    • Devaux A, Flammarion P, Bernardon V, Garric J, Monod G. 1998. Monitoring of the chemical pollution of the river Rhone through measurement of DNA damage and cytochrome P4501A induction in chub (Leuciscus cephalus). Mar Environ Res 46:257-262.
    • (1998) Mar Environ Res , vol.46 , pp. 257-262
    • Devaux, A.1    Flammarion, P.2    Bernardon, V.3    Garric, J.4    Monod, G.5
  • 11
    • 0030175848 scopus 로고    scopus 로고
    • Detection of genotoxic effects on cells of liver and gills of B. rerio by means of single cell gel electrophoresis
    • Deventer K. 1996. Detection of genotoxic effects on cells of liver and gills of B. rerio by means of single cell gel electrophoresis. Bull Environ Contam Toxicol 56:911-918.
    • (1996) Bull Environ Contam Toxicol , vol.56 , pp. 911-918
    • Deventer, K.1
  • 12
    • 2642612810 scopus 로고    scopus 로고
    • Detection of primary DNA damage in Chlamydomonas reinhardtii by means of modified microgel electrophoresis
    • Erbes M, Wessler A, Obst U, Wild A. 1997. Detection of primary DNA damage in Chlamydomonas reinhardtii by means of modified microgel electrophoresis. Environ Mol Mutagen 30:448-458.
    • (1997) Environ Mol Mutagen , vol.30 , pp. 448-458
    • Erbes, M.1    Wessler, A.2    Obst, U.3    Wild, A.4
  • 14
    • 0032486087 scopus 로고    scopus 로고
    • Induction of somatic DNA damage as measured by single cell gel electrophoresis and point mutation in leaves of tobacco plants
    • Gichner T, Plewa MJ. 1998. Induction of somatic DNA damage as measured by single cell gel electrophoresis and point mutation in leaves of tobacco plants. Mutat Res (Fundam Mol Mech Mutat) 401:143-152.
    • (1998) Mutat Res (Fundam Mol Mech Mutat) , vol.401 , pp. 143-152
    • Gichner, T.1    Plewa, M.J.2
  • 15
    • 0028956450 scopus 로고
    • The concepts of tail moment and tail inertia in the single cell gel electrophoresis assay
    • Hellman B, Vaghef H, Boström B. 1995. The concepts of tail moment and tail inertia in the single cell gel electrophoresis assay. Mutat Res 336:123-131.
    • (1995) Mutat Res , vol.336 , pp. 123-131
    • Hellman, B.1    Vaghef, H.2    Boström, B.3
  • 16
    • 0031973021 scopus 로고    scopus 로고
    • The ability of the comet assay to discriminate between genotoxins and cytotoxins
    • Henderson L, Wolfreys A, Fedyk J, Bourner G, Windebank S. 1998. The ability of the Comet assay to discriminate between genotoxins and cytotoxins. Mutagenesis 13:89-94.
    • (1998) Mutagenesis , vol.13 , pp. 89-94
    • Henderson, L.1    Wolfreys, A.2    Fedyk, J.3    Bourner, G.4    Windebank, S.5
  • 17
    • 0030575556 scopus 로고    scopus 로고
    • The alkaline comet test on plant cells: A new genotoxicity test for DNA strand breaks in Vicia faba root cells
    • Koppen G, Verschaeve L. 1996. The alkaline comet test on plant cells: a new genotoxicity test for DNA strand breaks in Vicia faba root cells. Mutat Res (Environ Mutagen RS) 360:193-200.
    • (1996) Mutat Res (Environ Mutagen RS) , vol.360 , pp. 193-200
    • Koppen, G.1    Verschaeve, L.2
  • 19
    • 0032549460 scopus 로고    scopus 로고
    • DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring
    • Mitchelmore CL, Chipman JK. 1998. DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring. Mutat Res (Fundam Mol Mech Mutat) 399: 135-147.
    • (1998) Mutat Res (Fundam Mol Mech Mutat) , vol.399 , pp. 135-147
    • Mitchelmore, C.L.1    Chipman, J.K.2
  • 20
    • 0030272592 scopus 로고    scopus 로고
    • Detection of DNA damage in individual cells from marine organisms using the single cell gel assay
    • Nacci DE, Cayula S, Jackim E. 1996. Detection of DNA damage in individual cells from marine organisms using the single cell gel assay. Aquat Toxicol 35:197-210.
    • (1996) Aquat Toxicol , vol.35 , pp. 197-210
    • Nacci, D.E.1    Cayula, S.2    Jackim, E.3
  • 21
    • 0030997488 scopus 로고    scopus 로고
    • A fast comet assay variant for solid tissue cells: The assessment of DNA damage in higher plants
    • Navarrete MH, Carrera P, Demiguel M, Delatorre C. 1997. A fast comet assay variant for solid tissue cells: the assessment of DNA damage in higher plants. Mutat Res (Genet Toxicol EM) 389:271-277.
    • (1997) Mutat Res (Genet Toxicol EM) , vol.389 , pp. 271-277
    • Navarrete, M.H.1    Carrera, P.2    Demiguel, M.3    Delatorre, C.4
  • 22
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay
    • Olive PL, Banath JP, Durand RE. 1990. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "Comet" assay. Radiat Res 122:86-94.
    • (1990) Radiat Res , vol.122 , pp. 86-94
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 23
    • 0026592534 scopus 로고
    • Factors influencing DNA migration from individual cells subjected to gel electrophoresis
    • Olive PL, Wlodek D, Durand RE, Banath JP. 1992. Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp Cell Res 198:259-267.
    • (1992) Exp Cell Res , vol.198 , pp. 259-267
    • Olive, P.L.1    Wlodek, D.2    Durand, R.E.3    Banath, J.P.4
  • 24
    • 0021193203 scopus 로고
    • Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
    • Östling O, Johanson KJ. 1984. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem Biophys Res Commun 123:291-298.
    • (1984) Biochem Biophys Res Commun , vol.123 , pp. 291-298
    • Östling, O.1    Johanson, K.J.2
  • 25
    • 0029562550 scopus 로고
    • Alkaline single cell gel (comet) assay and genotoxicity monitoring using bullheads and carp
    • Pandrangi R, Petras M, Ralph S, Vrzoc M. 1995. Alkaline single cell gel (comet) assay and genotoxicity monitoring using bullheads and carp. Environ Mol Mutagen 26:345-356.
    • (1995) Environ Mol Mutagen , vol.26 , pp. 345-356
    • Pandrangi, R.1    Petras, M.2    Ralph, S.3    Vrzoc, M.4
  • 26
    • 0030851363 scopus 로고    scopus 로고
    • Genotoxicity monitoring of small bodies of water using two species of tadpoles and the alkaline single cell gel (comet) assay
    • Ralph S, Petras M. 1997. Genotoxicity monitoring of small bodies of water using two species of tadpoles and the alkaline single cell gel (comet) assay. Environ Mol Mutagen 29:418-430.
    • (1997) Environ Mol Mutagen , vol.29 , pp. 418-430
    • Ralph, S.1    Petras, M.2
  • 27
    • 0029957941 scopus 로고    scopus 로고
    • Alkaline single-cell gel (comet) assay and genotoxicity monitoring using two species of tadpoles
    • Ralph S, Petras M, Pandrangi P, Vrzoc M. 1996. Alkaline single-cell gel (comet) assay and genotoxicity monitoring using two species of tadpoles. Environ Mol Mutagen 28:112-120.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 112-120
    • Ralph, S.1    Petras, M.2    Pandrangi, P.3    Vrzoc, M.4
  • 28
    • 0001410557 scopus 로고
    • Estimation of DNA strand breaks in single mammalian cells
    • Hanawalt PC, Friedberg EC, Fox CF (eds): New York: Academic Press
    • Rydberg B, Johanson KJ. 1978. Estimation of DNA strand breaks in single mammalian cells. In Hanawalt PC, Friedberg EC, Fox CF (eds): DNA repair mechanisms. New York: Academic Press, pp 465-468.
    • (1978) DNA Repair Mechanisms , pp. 465-468
    • Rydberg, B.1    Johanson, K.J.2
  • 29
    • 0029921918 scopus 로고    scopus 로고
    • The comet assay for the detection of genotoxic damage in the earthworms : A promising tool for assessing the biological hazards of polluted sites
    • Salagovic J, Gilles J, Verschaeve L, Kalina I. 1996. The Comet assay for the detection of genotoxic damage in the earthworms : a promising tool for assessing the biological hazards of polluted sites. Folia Biol 42:17-21.
    • (1996) Folia Biol , vol.42 , pp. 17-21
    • Salagovic, J.1    Gilles, J.2    Verschaeve, L.3    Kalina, I.4
  • 31
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh NP, McCoy MT, Tice RR, Schneider EL. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191.
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 32
    • 0029940299 scopus 로고    scopus 로고
    • Contribution of apoptosis to observed DNA damage in mussel cells
    • Steinert SA. 1996. Contribution of apoptosis to observed DNA damage in mussel cells. Mar Environ Res 42:253-259.
    • (1996) Mar Environ Res , vol.42 , pp. 253-259
    • Steinert, S.A.1
  • 34
    • 0002987035 scopus 로고
    • The single cell gel/comet assay: A microgel electrophoretic technique for the detection of DNA damage and repair in individual cells
    • Phillipps DH, Venitt S (eds): Oxford: Bios Scientific Publishers
    • Tice RR. 1995. The single cell gel/comet assay: a microgel electrophoretic technique for the detection of DNA damage and repair in individual cells. In Phillipps DH, Venitt S (eds): Environmental Mutagenesis. Oxford: Bios Scientific Publishers, pp 315-339.
    • (1995) Environmental Mutagenesis , pp. 315-339
    • Tice, R.R.1
  • 35
    • 0026005914 scopus 로고
    • The single cell gel (SCG) assay: An electrophoretic technique for the detection of DNA damage in individual cells
    • Tice RR, Andrews PW, Hirai O, Singh NP. 1991. The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. Adv Exp Med Biol 283:157-164.
    • (1991) Adv Exp Med Biol , vol.283 , pp. 157-164
    • Tice, R.R.1    Andrews, P.W.2    Hirai, O.3    Singh, N.P.4
  • 36
    • 0028960465 scopus 로고
    • Single cell gel electrophoresis assay in the earthworm for the detection of genotoxic compounds in soils
    • Verschaeve L, Gilles J. 1995. Single cell gel electrophoresis assay in the earthworm for the detection of genotoxic compounds in soils. Bull Environ Contam Toxicol 54:112-119.
    • (1995) Bull Environ Contam Toxicol , vol.54 , pp. 112-119
    • Verschaeve, L.1    Gilles, J.2
  • 37
    • 0343864611 scopus 로고
    • The single cell gel electrophoresis technique or comet test for monitoring dioxin pollution and effects
    • Fiedler H, Frank H, Hutzinger O, Parzefall W, Riss A, editors. Austria: Federal Environmental Agency
    • Verschaeve L, Gilles J, Schoeters J, Van Cleuvenbergen R, De Fré R. 1993. The single cell gel electrophoresis technique or comet test for monitoring dioxin pollution and effects. In: Fiedler H, Frank H, Hutzinger O, Parzefall W, Riss A, editors. Organohalogen compounds 11, Austria: Federal Environmental Agency, pp 213-216.
    • (1993) Organohalogen Compounds 11 , pp. 213-216
    • Verschaeve, L.1    Gilles, J.2    Schoeters, J.3    Van Cleuvenbergen, R.4    De Fré, R.5
  • 38
    • 0032077880 scopus 로고    scopus 로고
    • Detection of DNA damage in stressed trout nucleated erythrocytes using the comet assay: Protection by nitroxide radicals
    • Villarini M, Moretti M, Damiani E, Greci L, Santroni AM, Fedeli D, Falcioni G. 1998. Detection of DNA damage in stressed trout nucleated erythrocytes using the comet assay: protection by nitroxide radicals. Free Radical Biol Med 24:1310-1315.
    • (1998) Free Radical Biol Med , vol.24 , pp. 1310-1315
    • Villarini, M.1    Moretti, M.2    Damiani, E.3    Greci, L.4    Santroni, A.M.5    Fedeli, D.6    Falcioni, G.7
  • 39
    • 0032513338 scopus 로고    scopus 로고
    • Evaluation of the comet assay as a method for the detection of DNA damage in the cells of a marine invertebrate. Mytilus edulis L. (Mollusca: Pelecypoda)
    • Wilson JT, Pascoe PL, Parry JM, Dixon DR. 1998. Evaluation of the comet assay as a method for the detection of DNA damage in the cells of a marine invertebrate. Mytilus edulis L. (Mollusca: Pelecypoda). Mutat Res (Fundam Mol Mech Mutat) 399:87-95.
    • (1998) Mutat Res (Fundam Mol Mech Mutat) , vol.399 , pp. 87-95
    • Wilson, J.T.1    Pascoe, P.L.2    Parry, J.M.3    Dixon, D.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.