Disposition and biological activity of benzo[a]pyrene-7,8-dione. A genotoxic metabolite generated by dihydrodiol dehydrogenase

Biochemistry

Volumn 35, Issue 42, 1996, Pages 13664-13672

  Flowers, Lynn ^a   Bleczinski, Wendy F ^a   Burczynski, Michael E ^a   Harvey, Ronald G ^b   Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; DIHYDRODIOL DEHYDROGENASE; DNA FRAGMENT; POLYCYCLIC AROMATIC HYDROCARBON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CHEMICAL MUTAGENESIS; DRUG ACTIVITY; GENOTOXICITY; LIVER CELL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; BENZOPYRENES; BENZOQUINONES; CELLS, CULTURED; DIHYDROXYDIHYDROBENZOPYRENES; DNA ADDUCTS; DNA DAMAGE; DNA FRAGMENTATION; DNA, SUPERHELICAL; DNA, VIRAL; LIVER; MALE; MUTAGENICITY TESTS; MUTAGENS; OXIDOREDUCTASES; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

ANIMALIA; LETHRINIDAE; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0029861681     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961077w     Document Type: Article

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