Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2a -/- mice

Methods in Enzymology

Volumn 507, Issue , 2012, Pages 171-185

  Montini, Eugenio ^a   Cesana, Daniela ^a  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

Author keywords

Gene deregulation by vector integration; Genotoxicity assays; Insertional mutagenesis; Vector integration impact

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; LENTIVIRUS VECTOR;

ARTICLE; BINDING SITE; BIOSAFETY; BLOOD DISEASE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL ISOLATION; CLINICAL TRIAL (TOPIC); EX VIVO GENE TRANSFER; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE THERAPY; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HOST CELL; IN VIVO STUDY; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

MURINAE; MUS;

EID: 84857560044     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-386509-0.00009-0     Document Type: Chapter

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