RHGF-2 is an essential Rho-1 specific RhoGEF that binds to the multi-PDZ domain scaffold protein MPZ-1 in Caenorhabditis elegans

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Lin, Li ^a   Tran, Thuy ^a   Hu, Shuang ^a   Cramer, Todd ^a   Komuniecki, Richard ^a   Steven, Robert M ^a  

^a UNIVERSITY OF TOLEDO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; PDZ PROTEIN; PROTEIN MPZ 1; PROTEIN PLEKHG5; PROTEIN RHO 1; PROTEIN RHOGEF; PROTEIN SYX; PROTEIN TECH; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HYBRID PROTEIN; MESSENGER RNA; MPZ 1 PROTEIN, C ELEGANS; MPZ-1 PROTEIN, C ELEGANS; RHGF 2 PROTEIN, C ELEGANS; RHGF-2 PROTEIN, C ELEGANS; RHO 1 PROTEIN, C ELEGANS; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; RHO-1 PROTEIN, C ELEGANS;

ARTICLE; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE DELETION; GENE EXPRESSION; GENE OVEREXPRESSION; GFP GENE; GROWTH REGULATION; HUMAN; HUMAN CELL; MAMMAL; MORPHOLOGY; MUTANT; NERVE CELL; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RHGF 2 GENE; SERUM RESPONSIVE ELEMENT; TRANSGENE; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; CELL SHAPE; CELL STRAIN HEK293; CHEMISTRY; CYTOLOGY; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; LOCOMOTION; METABOLISM; MUTATION; NERVOUS SYSTEM; PDZ DOMAIN; PROTEIN MOTIF; PROTEIN TRANSPORT; SUBCUTANEOUS TISSUE; TRANSGENIC ANIMAL;

AMINO ACID MOTIFS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARRIER PROTEINS; CELL SHAPE; ENZYME ACTIVATION; GREEN FLUORESCENT PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HUMANS; LOCOMOTION; MODELS, BIOLOGICAL; MUTATION; NERVOUS SYSTEM; NEURONS; PDZ DOMAINS; PROTEIN BINDING; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; RHO GTP-BINDING PROTEINS; RNA, MESSENGER; SUBCUTANEOUS TISSUE;

EID: 84857396042     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031499     Document Type: Article

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