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Volumn 383, Issue 4, 2008, Pages 747-752

The DH-PH Region of the Giant Protein UNC-89 Activates RHO-1 GTPase in Caenorhabditis elegans Body Wall Muscle

Author keywords

C. elegans; GEF; muscle; rho; UNC 89

Indexed keywords

BACTERIAL PROTEIN; MYOSIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNC 89 PROTEIN; UNCLASSIFIED DRUG;

EID: 53149141697     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.08.083     Document Type: Article
Times cited : (35)

References (25)
  • 1
    • 0028170820 scopus 로고
    • Small GTP-binding proteins and the regulation of the actin cytoskeleton
    • Hall A. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol. 10 (1994) 31-54
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 31-54
    • Hall, A.1
  • 2
    • 0033179296 scopus 로고    scopus 로고
    • GEFs: structural basis for their activation of small GTP-binding proteins
    • Cherfils J., and Chardin P. GEFs: structural basis for their activation of small GTP-binding proteins. Trends Biochem. Sci. 24 (1999) 306-311
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 306-311
    • Cherfils, J.1    Chardin, P.2
  • 3
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
    • Rossman K.L., Der C.J., and Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nature Rev. Mol. Cell Biol. 6 (2005) 167-180
    • (2005) Nature Rev. Mol. Cell Biol. , vol.6 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 4
    • 0029978282 scopus 로고    scopus 로고
    • The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains
    • Benian G.M., Tinley T.L., Tang X., and Borodovsky M. The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains. J. Cell Biol. 132 (1996) 835-848
    • (1996) J. Cell Biol. , vol.132 , pp. 835-848
    • Benian, G.M.1    Tinley, T.L.2    Tang, X.3    Borodovsky, M.4
  • 5
    • 0035833261 scopus 로고    scopus 로고
    • Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly
    • Young P., Ehler E., and Gautel M. Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly. J. Cell Biol. 154 (2001) 123-136
    • (2001) J. Cell Biol. , vol.154 , pp. 123-136
    • Young, P.1    Ehler, E.2    Gautel, M.3
  • 6
    • 0018961312 scopus 로고
    • Mutants with altered muscle structure of Caenorhabditis elegans
    • Waterston R.H., Thomson J.N., and Brenner S. Mutants with altered muscle structure of Caenorhabditis elegans. Dev. Biol. 77 (1980) 271-302
    • (1980) Dev. Biol. , vol.77 , pp. 271-302
    • Waterston, R.H.1    Thomson, J.N.2    Brenner, S.3
  • 7
    • 0032616278 scopus 로고    scopus 로고
    • The genetics and molecular biology of the titin/connectin-like proteins of invertebrates
    • Benian G.M., Ayme-Southgate A., and Tinley T.L. The genetics and molecular biology of the titin/connectin-like proteins of invertebrates. Rev. Physiol. Biochem. Pharmacol. 138 (1999) 235-268
    • (1999) Rev. Physiol. Biochem. Pharmacol. , vol.138 , pp. 235-268
    • Benian, G.M.1    Ayme-Southgate, A.2    Tinley, T.L.3
  • 8
    • 4143153989 scopus 로고    scopus 로고
    • Three new isoforms of Caenorhabditis elegans UNC-89 containing MLCK-like protein kinase domains
    • Small T.M., Gernert K.M., Flaherty D.B., Mercer K.B., Borodovsky M., and Benian G.M. Three new isoforms of Caenorhabditis elegans UNC-89 containing MLCK-like protein kinase domains. J. Mol. Biol. 342 (2004) 91-108
    • (2004) J. Mol. Biol. , vol.342 , pp. 91-108
    • Small, T.M.1    Gernert, K.M.2    Flaherty, D.B.3    Mercer, K.B.4    Borodovsky, M.5    Benian, G.M.6
  • 9
    • 33745712384 scopus 로고    scopus 로고
    • Titin/connectin-related proteins in C. elegans: a review and new findings
    • Ferrara T.M., Flaherty D.B., and Benian G.M. Titin/connectin-related proteins in C. elegans: a review and new findings. J. Muscle Res. Cell Motil. 26 (2005) 435-447
    • (2005) J. Muscle Res. Cell Motil. , vol.26 , pp. 435-447
    • Ferrara, T.M.1    Flaherty, D.B.2    Benian, G.M.3
  • 10
    • 0034284952 scopus 로고    scopus 로고
    • The yeast exchange assay, a new complementary method to screen for Dbl-like protein specificity: identification of a novel RhoA exchange factor
    • De Toledo M., Colombo K., Nagase T., Ohara O., Fort P., and Blangy A. The yeast exchange assay, a new complementary method to screen for Dbl-like protein specificity: identification of a novel RhoA exchange factor. FEBS Lett. 480 (2000) 287-292
    • (2000) FEBS Lett. , vol.480 , pp. 287-292
    • De Toledo, M.1    Colombo, K.2    Nagase, T.3    Ohara, O.4    Fort, P.5    Blangy, A.6
  • 11
    • 0020825822 scopus 로고
    • Differential localization of two myosins within nematode thick filaments
    • Miller III D.M., Ortiz I., Berliner G.C., and Epstein H.F. Differential localization of two myosins within nematode thick filaments. Cell 34 (1983) 477-490
    • (1983) Cell , vol.34 , pp. 477-490
    • Miller III, D.M.1    Ortiz, I.2    Berliner, G.C.3    Epstein, H.F.4
  • 12
    • 33750288512 scopus 로고    scopus 로고
    • CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos
    • Schonegg S., and Hyman A.A. CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos. Development 133 (2006) 3507-3516
    • (2006) Development , vol.133 , pp. 3507-3516
    • Schonegg, S.1    Hyman, A.A.2
  • 13
    • 33748202573 scopus 로고    scopus 로고
    • Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos
    • Motegi F., and Sugimoto A. Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos. Nature Cell Biol. 8 (2006) 978-985
    • (2006) Nature Cell Biol. , vol.8 , pp. 978-985
    • Motegi, F.1    Sugimoto, A.2
  • 14
    • 33748305551 scopus 로고    scopus 로고
    • CYK-4/GAP provides a localized cue to initiate anteroposterior polarity upon fertilization
    • Jenkins N., Saam J.R., and Mango S.E. CYK-4/GAP provides a localized cue to initiate anteroposterior polarity upon fertilization. Science 313 (2006) 1298-1301
    • (2006) Science , vol.313 , pp. 1298-1301
    • Jenkins, N.1    Saam, J.R.2    Mango, S.E.3
  • 15
    • 0036213717 scopus 로고    scopus 로고
    • Three-dimensional high-resolution second-harmonic generation imaging of endogenous structural proteins in biological tissues
    • Campagnola P.J., Millard A.C., Terasaki M., Hoppe P.E., Malone C.J., and Mohler W.A. Three-dimensional high-resolution second-harmonic generation imaging of endogenous structural proteins in biological tissues. Biophys. J. 82 (2002) 493-508
    • (2002) Biophys. J. , vol.82 , pp. 493-508
    • Campagnola, P.J.1    Millard, A.C.2    Terasaki, M.3    Hoppe, P.E.4    Malone, C.J.5    Mohler, W.A.6
  • 16
    • 0032549710 scopus 로고    scopus 로고
    • UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans
    • Steven R., Kubiseski T.J., Zheng H., Kulkarni S., Mancillas J., Ruiz Morales A., et al. UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans. Cell 92 (1998) 785-795
    • (1998) Cell , vol.92 , pp. 785-795
    • Steven, R.1    Kubiseski, T.J.2    Zheng, H.3    Kulkarni, S.4    Mancillas, J.5    Ruiz Morales, A.6
  • 17
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: biochemistry and biology
    • Jaffe A.B., and Hall A. Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21 (2005) 247-269
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 18
    • 0032571395 scopus 로고    scopus 로고
    • The low molecular weight GTPase Rho regulates myofibril formation and organization in neonatal rat ventricular myocytes. Involvement of Rho kinase
    • Hoshijima M., Sah V.P., Wang Y., Chien K.R., and Brown J.H. The low molecular weight GTPase Rho regulates myofibril formation and organization in neonatal rat ventricular myocytes. Involvement of Rho kinase. J. Biol. Chem. 273 (1998) 7725-7730
    • (1998) J. Biol. Chem. , vol.273 , pp. 7725-7730
    • Hoshijima, M.1    Sah, V.P.2    Wang, Y.3    Chien, K.R.4    Brown, J.H.5
  • 20
    • 33748289980 scopus 로고    scopus 로고
    • Caenorhabditis elegans UNC-96 is a new component of M-lines that interacts with UNC-98 and paramyosin and is required in adult muscle for assembly and/or maintenance of thick filaments
    • Mercer K.B., Miller R.K., Tinley T.L., Sheth S., Qadota H., and Benian G.M. Caenorhabditis elegans UNC-96 is a new component of M-lines that interacts with UNC-98 and paramyosin and is required in adult muscle for assembly and/or maintenance of thick filaments. Mol. Biol. Cell 17 (2006) 3832-3847
    • (2006) Mol. Biol. Cell , vol.17 , pp. 3832-3847
    • Mercer, K.B.1    Miller, R.K.2    Tinley, T.L.3    Sheth, S.4    Qadota, H.5    Benian, G.M.6
  • 21
    • 48749118801 scopus 로고    scopus 로고
    • A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegans
    • Qadota H., McGaha L.A., Mercer K.B., Stark T.J., Ferrara T.M., and Benian G.M. A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegans. Mol. Biol. Cell 19 (2008) 2424-2432
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2424-2432
    • Qadota, H.1    McGaha, L.A.2    Mercer, K.B.3    Stark, T.J.4    Ferrara, T.M.5    Benian, G.M.6
  • 22
    • 0027319325 scopus 로고
    • Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin
    • Nonet M.L., Grundahl K., Meyer B.J., and Rand J.B. Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin. Cell 73 (1993) 1291-1305
    • (1993) Cell , vol.73 , pp. 1291-1305
    • Nonet, M.L.1    Grundahl, K.2    Meyer, B.J.3    Rand, J.B.4
  • 23
    • 35848949782 scopus 로고    scopus 로고
    • Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle
    • Qadota H., Mercer K.B., Miller R.K., Kaibuchi K., and Benian G.M. Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle. Mol. Biol. Cell 18 (2007) 4317-4326
    • (2007) Mol. Biol. Cell , vol.18 , pp. 4317-4326
    • Qadota, H.1    Mercer, K.B.2    Miller, R.K.3    Kaibuchi, K.4    Benian, G.M.5
  • 24
    • 0035941485 scopus 로고    scopus 로고
    • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
    • Timmons L., Court D.L., and Fire A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263 (2001) 103-112
    • (2001) Gene , vol.263 , pp. 103-112
    • Timmons, L.1    Court, D.L.2    Fire, A.3
  • 25
    • 0037031152 scopus 로고    scopus 로고
    • Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi
    • Simmer F., Tijsterman M., Parrish S., Koushika S.P., Nonet M.L., Fire A., et al. Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Curr. Biol. 12 (2002) 1317-1319
    • (2002) Curr. Biol. , vol.12 , pp. 1317-1319
    • Simmer, F.1    Tijsterman, M.2    Parrish, S.3    Koushika, S.P.4    Nonet, M.L.5    Fire, A.6


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