Metabolic activation of benzo[c]phenanthrene by cytochrome P450 enzymes in human liver and lung

Chemical Research in Toxicology

Volumn 14, Issue 6, 2001, Pages 686-693

  Baum, M ^a   Amin, S ^a,b   Guengerich, F P ^a,c   Hecht, S S ^a,d   Kohl W ^a   Eisenbrand, G ^a  

^a University of Koblenz Landau   (Germany)

^b AMERICAN HEALTH FOUNDATION   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE DERIVATIVE; BENZO[C]PHENANTHRENE; BENZO[C]PHENANTHRENE 3,4 DIHYDRODIOL; BENZO[C]PHENANTHRENE 3,4 DIHYDRODIOL 1,2 EPOXIDE; BENZO[C]PHENANTHRENE 5,6 DIHYDRODIOL; CYTOCHROME P450; CYTOCHROME P450 1B1; CYTOCHROME P450 INHIBITOR; EPOXIDE; MICROSOME ENZYME; PHENANTHRENE DERIVATIVE; POLYCYCLIC AROMATIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CARCINOGENESIS; CATALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; METABOLISM; METABOLITE; PROTEIN EXPRESSION;

EID: 0034978878     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx000240s     Document Type: Article

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