Ablation of neurons expressing agouti-related protein, but not melanin concentrating hormone, in leptin-deficient mice restores metabolic functions and fertility

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 8, 2012, Pages 3155-3160

  Wu, Qi ^a   Whiddon, Benjamin B ^a   Palmiter, Richard D ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Diphtheria toxin; Gonadotropin releasing protein; Kisspeptin; Neuropeptide Y; Norepinephrine

Indexed keywords

AGOUTI RELATED PROTEIN; DIPHTHERIA TOXIN; LEPTIN; MELANIN CONCENTRATING HORMONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTICLE; BODY WEIGHT; CELL POPULATION; CONTROLLED STUDY; FEMALE; FERTILITY; FOOD INTAKE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HYPOTHALAMUS; MALE; METABOLISM; MORTALITY; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGOUTI-RELATED PROTEIN; ANIMALS; BODY WEIGHT; FEEDING BEHAVIOR; FERTILITY; GLUCOSE; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; HYPOTHALAMIC HORMONES; LEPTIN; MELANINS; MICE; MICE, INBRED C57BL; MICE, OBESE; NEURONS; OBESITY; PITUITARY HORMONES; SURVIVAL ANALYSIS;

EID: 84857374972     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1120501109     Document Type: Article

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