메뉴 건너뛰기




Volumn 9, Issue 2, 2009, Pages 117-123

The Geometry of Leptin Action in the Brain: More Complicated Than a Simple ARC

Author keywords

HUMDISEASE

Indexed keywords

GONADORELIN; KISSPEPTIN; LEPTIN; LEPTIN RECEPTOR; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN;

EID: 58749086043     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2008.12.001     Document Type: Review
Times cited : (252)

References (71)
  • 5
    • 0031766722 scopus 로고    scopus 로고
    • Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and proopiomelanocortin
    • Bergen H.T., Mizuno T.M., Taylor J., and Mobbs C.V. Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and proopiomelanocortin. Endocrinology 139 (1998) 4483-4488
    • (1998) Endocrinology , vol.139 , pp. 4483-4488
    • Bergen, H.T.1    Mizuno, T.M.2    Taylor, J.3    Mobbs, C.V.4
  • 6
    • 42449086900 scopus 로고    scopus 로고
    • Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome
    • Bingham N.C., Anderson K.K., Reuter A.L., Stallings N.R., and Parker K.L. Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome. Endocrinology 149 (2008) 2138-2148
    • (2008) Endocrinology , vol.149 , pp. 2138-2148
    • Bingham, N.C.1    Anderson, K.K.2    Reuter, A.L.3    Stallings, N.R.4    Parker, K.L.5
  • 7
    • 0036553037 scopus 로고    scopus 로고
    • The melanocortin receptors: lessons from knockout models
    • Butler A.A., and Cone R.D. The melanocortin receptors: lessons from knockout models. Neuropeptides 36 (2002) 77-84
    • (2002) Neuropeptides , vol.36 , pp. 77-84
    • Butler, A.A.1    Cone, R.D.2
  • 9
    • 34547849517 scopus 로고    scopus 로고
    • Chronic food restriction: enhancing effects on drug reward and striatal cell signaling
    • Carr K.D. Chronic food restriction: enhancing effects on drug reward and striatal cell signaling. Physiol. Behav. 91 (2006) 459-472
    • (2006) Physiol. Behav. , vol.91 , pp. 459-472
    • Carr, K.D.1
  • 10
    • 33646929507 scopus 로고    scopus 로고
    • Female odors stimulate CART neurons in the ventral premammillary nucleus of male rats
    • Cavalcante J.C., Bittencourt J.C., and Elias C.F. Female odors stimulate CART neurons in the ventral premammillary nucleus of male rats. Physiol. Behav. 88 (2006) 160-166
    • (2006) Physiol. Behav. , vol.88 , pp. 160-166
    • Cavalcante, J.C.1    Bittencourt, J.C.2    Elias, C.F.3
  • 11
    • 0030865242 scopus 로고    scopus 로고
    • The reproductive side of leptin
    • Chehab F.F. The reproductive side of leptin. Nat. Med. 3 (1997) 952-953
    • (1997) Nat. Med. , vol.3 , pp. 952-953
    • Chehab, F.F.1
  • 18
    • 0038173575 scopus 로고    scopus 로고
    • Lateral hypothalamic neuropeptides in reward and drug addiction
    • DiLeone R.J., Georgescu D., and Nestler E.J. Lateral hypothalamic neuropeptides in reward and drug addiction. Life Sci. 73 (2003) 759-768
    • (2003) Life Sci. , vol.73 , pp. 759-768
    • DiLeone, R.J.1    Georgescu, D.2    Nestler, E.J.3
  • 19
    • 0031906674 scopus 로고    scopus 로고
    • Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei
    • Elmquist J.K., Ahima R.S., Elia C.F., Flier J.S., and Saper C.B. Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc. Natl. Acad. Sci. USA 95 (1998) 741-746
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 741-746
    • Elmquist, J.K.1    Ahima, R.S.2    Elia, C.F.3    Flier, J.S.4    Saper, C.B.5
  • 21
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: hypothalamic control of food intake and body weight
    • Elmquist J.K., Elias C.F., and Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22 (1999) 221-232
    • (1999) Neuron , vol.22 , pp. 221-232
    • Elmquist, J.K.1    Elias, C.F.2    Saper, C.B.3
  • 22
    • 27744436291 scopus 로고    scopus 로고
    • Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis
    • Elmquist J.K., Coppari R., Balthasar N., Ichinose M., and Lowell B.B. Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis. J. Comp. Neurol. 493 (2005) 63-71
    • (2005) J. Comp. Neurol. , vol.493 , pp. 63-71
    • Elmquist, J.K.1    Coppari, R.2    Balthasar, N.3    Ichinose, M.4    Lowell, B.B.5
  • 23
    • 35549009434 scopus 로고    scopus 로고
    • Differential accessibility of circulating leptin to individual hypothalamic sites
    • Faouzi M., Leshan R., Bjornholm M., Hennessey T., Jones J., and Munzberg H. Differential accessibility of circulating leptin to individual hypothalamic sites. Endocrinology 148 (2007) 5414-5423
    • (2007) Endocrinology , vol.148 , pp. 5414-5423
    • Faouzi, M.1    Leshan, R.2    Bjornholm, M.3    Hennessey, T.4    Jones, J.5    Munzberg, H.6
  • 25
  • 26
    • 0034614698 scopus 로고    scopus 로고
    • Modulation of brain reward circuitry by leptin
    • Fulton S., Woodside B., and Shizgal P. Modulation of brain reward circuitry by leptin. Science 287 (2000) 125-128
    • (2000) Science , vol.287 , pp. 125-128
    • Fulton, S.1    Woodside, B.2    Shizgal, P.3
  • 29
    • 33745916162 scopus 로고    scopus 로고
    • Kisspepeptin-GPR54 signaling in the neuroendocrine reproductive axis
    • Gottsch M.L., Clifton D.K., and Steiner R.A. Kisspepeptin-GPR54 signaling in the neuroendocrine reproductive axis. Mol. Cell. Endocrinol. 254-255 (2006) 91-96
    • (2006) Mol. Cell. Endocrinol. , vol.254-255 , pp. 91-96
    • Gottsch, M.L.1    Clifton, D.K.2    Steiner, R.A.3
  • 30
    • 33845911799 scopus 로고    scopus 로고
    • Distributed neural control of energy balance: contributions from hindbrain and hypothalamus
    • Grill H.J. Distributed neural control of energy balance: contributions from hindbrain and hypothalamus. Obesity (Silver Spring) 14 Suppl 5 (2006) 216S-221S
    • (2006) Obesity (Silver Spring) , vol.14 , Issue.SUPPL. 5
    • Grill, H.J.1
  • 32
    • 25644432796 scopus 로고    scopus 로고
    • A role for lateral hypothalamic orexin neurons in reward seeking
    • Harris G.C., Wimmer M., and Aston-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature 437 (2005) 556-559
    • (2005) Nature , vol.437 , pp. 556-559
    • Harris, G.C.1    Wimmer, M.2    Aston-Jones, G.3
  • 36
    • 34249785695 scopus 로고    scopus 로고
    • Leptin and the control of food intake: neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin
    • Huo L., Maeng L., Bjorbaek C., and Grill H.J. Leptin and the control of food intake: neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin. Endocrinology 148 (2007) 2189-2197
    • (2007) Endocrinology , vol.148 , pp. 2189-2197
    • Huo, L.1    Maeng, L.2    Bjorbaek, C.3    Grill, H.J.4
  • 37
    • 27744599679 scopus 로고    scopus 로고
    • A proposed hypothalamic-thalamic-striatal axis for the integration of energy balance, arousal, and food reward
    • Kelley A.E., Baldo B.A., and Pratt W.E. A proposed hypothalamic-thalamic-striatal axis for the integration of energy balance, arousal, and food reward. J. Comp. Neurol. 493 (2005) 72-85
    • (2005) J. Comp. Neurol. , vol.493 , pp. 72-85
    • Kelley, A.E.1    Baldo, B.A.2    Pratt, W.E.3
  • 38
    • 0034457883 scopus 로고    scopus 로고
    • In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin
    • Kim Y.B., Uotani S., Pierroz D.D., Flier J.S., and Kahn B.B. In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. Endocrinology 141 (2000) 2328-2339
    • (2000) Endocrinology , vol.141 , pp. 2328-2339
    • Kim, Y.B.1    Uotani, S.2    Pierroz, D.D.3    Flier, J.S.4    Kahn, B.B.5
  • 39
    • 31944452253 scopus 로고    scopus 로고
    • The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
    • King B.M. The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol. Behav. 87 (2006) 221-244
    • (2006) Physiol. Behav. , vol.87 , pp. 221-244
    • King, B.M.1
  • 42
    • 27344431720 scopus 로고    scopus 로고
    • NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
    • Luquet S., Perez F.A., Hnasko T.S., and Palmiter R.D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science 310 (2005) 683-685
    • (2005) Science , vol.310 , pp. 683-685
    • Luquet, S.1    Perez, F.A.2    Hnasko, T.S.3    Palmiter, R.D.4
  • 46
    • 0038747134 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin
    • Munzberg H., Huo L., Nillni E.A., Hollenberg A.N., and Bjorbaek C. Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin. Endocrinology 144 (2003) 2121-2131
    • (2003) Endocrinology , vol.144 , pp. 2121-2131
    • Munzberg, H.1    Huo, L.2    Nillni, E.A.3    Hollenberg, A.N.4    Bjorbaek, C.5
  • 47
    • 0031813699 scopus 로고    scopus 로고
    • Evidence for GnRH regulation by leptin: leptin administration prevents reduced pulsatile LH secretion during fasting
    • Nagatani S., Guthikonda P., Thompson R.C., Tsukamura H., Maeda K.I., and Foster D.L. Evidence for GnRH regulation by leptin: leptin administration prevents reduced pulsatile LH secretion during fasting. Neuroendocrinology 67 (1998) 370-376
    • (1998) Neuroendocrinology , vol.67 , pp. 370-376
    • Nagatani, S.1    Guthikonda, P.2    Thompson, R.C.3    Tsukamura, H.4    Maeda, K.I.5    Foster, D.L.6
  • 48
    • 27644454004 scopus 로고    scopus 로고
    • Is there a common molecular pathway for addiction?
    • Nestler E.J. Is there a common molecular pathway for addiction?. Nat. Neurosci. 8 (2005) 1445-1449
    • (2005) Nat. Neurosci. , vol.8 , pp. 1445-1449
    • Nestler, E.J.1
  • 49
    • 4544306391 scopus 로고    scopus 로고
    • Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis
    • Niswender K.D., Baskin D.G., and Schwartz M.W. Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis. Trends Endocrinol. Metab. 15 (2004) 362-369
    • (2004) Trends Endocrinol. Metab. , vol.15 , pp. 362-369
    • Niswender, K.D.1    Baskin, D.G.2    Schwartz, M.W.3
  • 54
    • 34347325204 scopus 로고    scopus 로고
    • Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice
    • Roseberry A.G., Painter T., Mark G.P., and Williams J.T. Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice. J. Neurosci. 27 (2007) 7021-7027
    • (2007) J. Neurosci. , vol.27 , pp. 7021-7027
    • Roseberry, A.G.1    Painter, T.2    Mark, G.P.3    Williams, J.T.4
  • 55
    • 0036093071 scopus 로고    scopus 로고
    • Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones
    • Rosenbaum M., Murphy E.M., Heymsfield S.B., Matthews D.E., and Leibel R.L. Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones. J. Clin. Endocrinol. Metab. 87 (2002) 2391-2394
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 2391-2394
    • Rosenbaum, M.1    Murphy, E.M.2    Heymsfield, S.B.3    Matthews, D.E.4    Leibel, R.L.5
  • 56
    • 45549098243 scopus 로고    scopus 로고
    • Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism
    • Rother E., Konner A.C., and Bruning J.C. Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism. Am. J. Physiol. Endocrinol. Metab. 294 (2008) E810-E816
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.294
    • Rother, E.1    Konner, A.C.2    Bruning, J.C.3
  • 58
    • 0032079533 scopus 로고    scopus 로고
    • Organization and regulation of sexually dimorphic neuroendocrine pathways
    • Simerly R.B. Organization and regulation of sexually dimorphic neuroendocrine pathways. Behav. Brain Res. 92 (1998) 195-203
    • (1998) Behav. Brain Res. , vol.92 , pp. 195-203
    • Simerly, R.B.1
  • 59
    • 32444449631 scopus 로고    scopus 로고
    • Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice
    • Smart J.L., Tolle V., and Low M.J. Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice. J. Clin. Invest. 116 (2006) 495-505
    • (2006) J. Clin. Invest. , vol.116 , pp. 495-505
    • Smart, J.L.1    Tolle, V.2    Low, M.J.3
  • 61
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH-> arcuate nucleus microcircuits and their reorganization by fasting
    • Sternson S.M., Shepherd G.M., and Friedman J.M. Topographic mapping of VMH-> arcuate nucleus microcircuits and their reorganization by fasting. Nat. Neurosci. 8 (2005) 1356-1363
    • (2005) Nat. Neurosci. , vol.8 , pp. 1356-1363
    • Sternson, S.M.1    Shepherd, G.M.2    Friedman, J.M.3
  • 62
    • 33750916941 scopus 로고    scopus 로고
    • KiSS-1 and reproduction: focus on its role in the metabolic regulation of fertility
    • Tena-Sempere M. KiSS-1 and reproduction: focus on its role in the metabolic regulation of fertility. Neuroendocrinology 83 (2006) 275-281
    • (2006) Neuroendocrinology , vol.83 , pp. 275-281
    • Tena-Sempere, M.1
  • 63
    • 0037345605 scopus 로고    scopus 로고
    • Structural characterization of a hypothalamic visceromotor pattern generator network
    • Thompson R.H., and Swanson L.W. Structural characterization of a hypothalamic visceromotor pattern generator network. Brain Res. Brain Res. Rev. 41 (2003) 153-202
    • (2003) Brain Res. Brain Res. Rev. , vol.41 , pp. 153-202
    • Thompson, R.H.1    Swanson, L.W.2
  • 68
    • 33845518516 scopus 로고    scopus 로고
    • Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation
    • Williams D.L., Baskin D.G., and Schwartz M.W. Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation. Diabetes 55 (2006) 3387-3393
    • (2006) Diabetes , vol.55 , pp. 3387-3393
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 71
    • 40849092403 scopus 로고    scopus 로고
    • Induction of Fos-immunoreactivity in the rat brain following disinhibition of the dorsomedial hypothalamus
    • Zaretskaia M.V., Zaretsky D.V., Sarkar S., Shekhar A., and DiMicco J.A. Induction of Fos-immunoreactivity in the rat brain following disinhibition of the dorsomedial hypothalamus. Brain Res. 1200 (2008) 39-50
    • (2008) Brain Res. , vol.1200 , pp. 39-50
    • Zaretskaia, M.V.1    Zaretsky, D.V.2    Sarkar, S.3    Shekhar, A.4    DiMicco, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.