-
1
-
-
79953151733
-
Modeling opportunities in comparative oncology for drug development
-
I. Gordon, and C. Khanna Modeling opportunities in comparative oncology for drug development ILAR J 51 2010 214 220
-
(2010)
ILAR J
, vol.51
, pp. 214-220
-
-
Gordon, I.1
Khanna, C.2
-
2
-
-
2042458747
-
Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials
-
DOI 10.1054/bjoc.2001.1796
-
J.I. Johnson, S. Decker, and D. Zaharevitz Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials Br J Cancer 84 2001 1424 1431 (Pubitemid 32522115)
-
(2001)
British Journal of Cancer
, vol.84
, Issue.10
, pp. 1424-1431
-
-
Johnson, J.I.1
Decker, S.2
Zaharevitz, D.3
Rubinstein, L.V.4
Venditti, J.M.5
Schepartz, S.6
Kalyandrug, S.7
Christian, M.8
Arbuck, S.9
Hollingshead, M.10
Sausville, E.A.11
-
3
-
-
0032880047
-
Widespread intraspecies cross-contamination of human tumor cell lines arising at source
-
DOI 10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
-
R.A. MacLeod, W.G. Dirks, and Y. Matsuo Widespread intraspecies cross-contamination of human tumor cell lines arising at source Int J Cancer 83 1999 555 563 (Pubitemid 29489873)
-
(1999)
International Journal of Cancer
, vol.83
, Issue.4
, pp. 555-563
-
-
MacLeod, R.A.F.1
Dirks, W.G.2
Matsuo, Y.3
Kaufmann, M.4
Milch, H.5
Drexler, H.G.6
-
4
-
-
0036549592
-
HeLa cells 50 years on: The good, the bad and the ugly
-
J.R. Masters HeLa cells 50 years on: the good, the bad and the ugly Nat Rev Cancer 2 2002 315 319 (Pubitemid 37336517)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.4
, pp. 315-319
-
-
Masters, J.R.1
-
5
-
-
71049182586
-
Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa
-
A. Magalhães, J. Gomes, and M.N. Ismail Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa Glycobiology 19 2009 1525 1536
-
(2009)
Glycobiology
, vol.19
, pp. 1525-1536
-
-
Magalhães, A.1
Gomes, J.2
Ismail, M.N.3
-
6
-
-
64249106832
-
Mouse xenograft models vs GEM models for human cancer therapeutics
-
A. Richmond, and Y. Su Mouse xenograft models vs GEM models for human cancer therapeutics Dis Model Mech 1 2008 78 82
-
(2008)
Dis Model Mech
, vol.1
, pp. 78-82
-
-
Richmond, A.1
Su, Y.2
-
7
-
-
1942518888
-
Spontaneous and genetically engineered animal models: Use in preclinical cancer drug development
-
DOI 10.1016/j.ejca.2003.11.031, PII S0959804904000498
-
K. Hansen, and C. Khanna Spontaneous and genetically engineered animal models; use in preclinical cancer drug development Eur J Cancer 40 2004 858 880 (Pubitemid 38519765)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.6
, pp. 858-880
-
-
Hansen, K.1
Khanna, C.2
-
8
-
-
56949087846
-
Lost in translation: Problems and pitfalls in translating laboratory observations to clinical utility
-
R. Simon Lost in translation: problems and pitfalls in translating laboratory observations to clinical utility Eur J Cancer 44 2008 2707 2713
-
(2008)
Eur J Cancer
, vol.44
, pp. 2707-2713
-
-
Simon, R.1
-
9
-
-
1842510682
-
Trials, Tribulations, and Trends in Tumor Modeling in Mice
-
DOI 10.1080/01926230490424770
-
J.C. Schuh Trials, tribulations, and trends in tumor modeling in mice Toxicol Pathol 32 2004 53 66 (Pubitemid 38437568)
-
(2004)
Toxicologic Pathology
, vol.32
, Issue.SUPPL. 1
, pp. 53-66
-
-
Schuh, J.C.L.1
-
10
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
N.W. Kim, M.A. Piatyszek, and K.R. Prowse Specific association of human telomerase activity with immortal cells and cancer Science 266 1994 2011 2015
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
-
11
-
-
0029040101
-
Developmental and tissue-specific regulation of mouse telomerase and telomere length
-
K.R. Prowse, and C.W. Greider Developmental and tissue-specific regulation of mouse telomerase and telomere length Proc Natl Acad Sci U S A 92 1995 4818 4822
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4818-4822
-
-
Prowse, K.R.1
Greider, C.W.2
-
12
-
-
1342288971
-
Comparative biology of mouse versus human cells: Modelling human cancer in mice
-
A. Rangarajan, and R.A. Weinberg Opinion: comparative biology of mouse versus human cells: modelling human cancer in mice Nat Rev Cancer 3 2003 952 959 (Pubitemid 37500180)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.12
, pp. 952-959
-
-
Rangarajan, A.1
Weinberg, R.A.2
-
13
-
-
62749107149
-
In vivo/ex vivo and in situ assays used in cancer research: A brief review
-
B.A. Teicher In vivo/ex vivo and in situ assays used in cancer research: a brief review Toxicol Pathol 37 2009 114 122
-
(2009)
Toxicol Pathol
, vol.37
, pp. 114-122
-
-
Teicher, B.A.1
-
14
-
-
0025164639
-
Spontaneous tumors in dogs and cats: Models for the study of cancer biology and treatment
-
E.G. MacEwen Spontaneous tumors in dogs and cats: models for the study of cancer biology and treatment Cancer Metastasis Rev 9 1990 125 136 (Pubitemid 20311829)
-
(1990)
Cancer and Metastasis Reviews
, vol.9
, Issue.2
, pp. 125-136
-
-
MacEwen, E.G.1
-
15
-
-
0033671255
-
Spontaneously occurring tumors of companion animals as models for human cancer
-
D.M. Vail, and E.G. MacEwen Spontaneously occurring tumors of companion animals as models for human cancer Cancer Invest 18 2000 781 792
-
(2000)
Cancer Invest
, vol.18
, pp. 781-792
-
-
Vail, D.M.1
MacEwen, E.G.2
-
18
-
-
38549112058
-
Translation of new cancer treatments from pet dogs to humans
-
DOI 10.1038/nrc2273, PII NRC2273
-
M. Paoloni, and C. Khanna Translation of new cancer treatments from pet dogs to humans Nat Rev Cancer 8 2008 147 156 (Pubitemid 351161319)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.2
, pp. 147-156
-
-
Paoloni, M.1
Khanna, C.2
-
19
-
-
0141596080
-
The dog genome: Survey sequencing and comparative analysis
-
DOI 10.1126/science.1086432
-
E.F. Kirkness, V. Bafna, and A.L. Halpern The dog genome: survey sequencing and comparative analysis Science 301 2003 1898 1903 (Pubitemid 37221394)
-
(2003)
Science
, vol.301
, Issue.5641
, pp. 1898-1903
-
-
Kirkness, E.F.1
Bafna, V.2
Halpern, A.L.3
Levy, S.4
Remington, K.5
Rusch, D.B.6
Delcher, A.L.7
Pop, M.8
Wang, W.9
Fraser, C.M.10
Venter, J.C.11
-
20
-
-
28644447707
-
Genome sequence, comparative analysis and haplotype structure of the domestic dog
-
DOI 10.1038/nature04338
-
K. Lindblad-Toh, C.M. Wade, and T.S. Mikkelsen Genome sequence, comparative analysis and haplotype structure of the domestic dog Nature 438 2005 803 819 (Pubitemid 41753059)
-
(2005)
Nature
, vol.438
, Issue.7069
, pp. 803-819
-
-
Lindblad-Toh, K.1
Wade, C.M.2
Mikkelsen, T.S.3
Karlsson, E.K.4
Jaffe, D.B.5
Kamal, M.6
Clamp, M.7
Chang, J.L.8
Kulbokas III, E.J.9
Zody, M.C.10
Mauceli, E.11
Xie, X.12
Breen, M.13
Wayne, R.K.14
Ostrander, E.A.15
Ponting, C.P.16
Galibert, F.17
Smith, D.R.18
DeJong, P.J.19
Kirkness, E.20
Alvarez, P.21
Biagi, T.22
Brockman, W.23
Butler, J.24
Chin, C.-W.25
Cook, A.26
Cuff, J.27
Daly, M.J.28
DeCaprio, D.29
Gnerre, S.30
Grabherr, M.31
Kellis, M.32
Kleber, M.33
Bardeleben, C.34
Goodstadt, L.35
Heger, A.36
Hitte, C.37
Kim, L.38
Koepfli, K.-P.39
Parker, H.G.40
Pollinger, J.P.41
Searle, S.M.J.42
Sutter, N.B.43
Thomas, R.44
Webber, C.45
Lander, E.S.46
more..
-
21
-
-
65249091846
-
Comparative expression pathway analysis of human and canine mammary tumors
-
P. Uva, L. Aurisicchio, and J. Watters Comparative expression pathway analysis of human and canine mammary tumors BMC Genomics 10 2009 135
-
(2009)
BMC Genomics
, vol.10
, pp. 135
-
-
Uva, P.1
Aurisicchio, L.2
Watters, J.3
-
22
-
-
34250687198
-
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity
-
DOI 10.1073/pnas.0702507104
-
L.H. Saal, P. Johansson, and K. Holm Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity Proc Natl Acad Sci U S A 104 2007 7564 7569 (Pubitemid 47185946)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.18
, pp. 7564-7569
-
-
Saal, L.H.1
Johansson, P.2
Holm, K.3
Gruvberger-Saal, S.K.4
She, Q.-B.5
Maurer, M.6
Koujak, S.7
Ferrando, A.A.8
Malmstrom, P.9
Memeo, L.10
Isola, J.11
Bendahl, P.-O.12
Rosen, N.13
Hibshoosh, H.14
Ringner, M.15
Borg, A.16
Parsons, R.17
-
23
-
-
44449159236
-
Reactive oxygen species and HIF-1 signalling in cancer
-
A. Galanis, A. Pappa, and A. Giannakakis Reactive oxygen species and HIF-1 signalling in cancer Cancer Lett 266 2008 12 20
-
(2008)
Cancer Lett
, vol.266
, pp. 12-20
-
-
Galanis, A.1
Pappa, A.2
Giannakakis, A.3
-
25
-
-
33847314539
-
The phosphatidyl inositol 3-kinase signaling network: Implications for human breast cancer
-
DOI 10.1038/sj.onc.1210202, PII 1210202
-
R.L. Dillon, D.E. White, and W.J. Muller The phosphatidyl inositol 3- kinase signaling network: implications for human breast cancer Oncogene 26 2007 1338 1345 (Pubitemid 46328463)
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1338-1345
-
-
Dillon, R.L.1
White, D.E.2
Muller, W.J.3
-
26
-
-
11244258643
-
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
-
DOI 10.1038/ng1490
-
A. Sweet-Cordero, S. Mukherjee, and A. Subramanian An oncogenic KRAS2 expression signature identified by cross-species gene- expression analysis Nat Genet 37 2005 48 55 (Pubitemid 40070939)
-
(2005)
Nature Genetics
, vol.37
, Issue.1
, pp. 48-55
-
-
Sweet-Cordero, A.1
Mukherjee, S.2
Subramanian, A.3
You, H.4
Roix, J.J.5
Ladd-Acosta, C.6
Mesirov, J.7
Golub, T.R.8
Jacks, T.9
-
27
-
-
77149136791
-
Reduced PTEN protein expression and its prognostic implications in canine and feline mammary tumors
-
L. Ressel, F. Millanta, E. Caleri, V.M. Innocenti, and A. Poli Reduced PTEN protein expression and its prognostic implications in canine and feline mammary tumors Vet Pathol 46 2009 860 868
-
(2009)
Vet Pathol
, vol.46
, pp. 860-868
-
-
Ressel, L.1
Millanta, F.2
Caleri, E.3
Innocenti, V.M.4
Poli, A.5
-
28
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
K.M. Cadigan, and R. Nusse Wnt signaling: a common theme in animal development Genes Dev 11 1997 3286 3305 (Pubitemid 28023954)
-
(1997)
Genes and Development
, vol.11
, Issue.24
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
29
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
DOI 10.1038/nrc2389, PII NRC2389
-
A. Klaus, and W. Birchmeier Wnt signalling and its impact on development and cancer Nat Rev Cancer 8 2008 387 398 (Pubitemid 351589714)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.5
, pp. 387-398
-
-
Klaus, A.1
Birchmeier, W.2
-
30
-
-
40849116461
-
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
-
DOI 10.1038/sj.bjc.6604259, PII 6604259
-
H. Suzuki, M. Toyota, and H. Carraway Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer Br J Cancer 98 2008 1147 1156 (Pubitemid 351399804)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.6
, pp. 1147-1156
-
-
Suzuki, H.1
Toyota, M.2
Caraway, H.3
Gabrielson, E.4
Ohmura, T.5
Fujikane, T.6
Nishikawa, N.7
Sogabe, Y.8
Nojima, M.9
Sonoda, T.10
Mori, M.11
Hirata, K.12
Imai, K.13
Shinomura, Y.14
Baylin, S.B.15
Tokino, T.16
-
31
-
-
47249123731
-
CDNA microarray profiles of canine mammary tumour cell lines reveal deregulated pathways pertaining to their phenotype
-
DOI 10.1111/j.1365-2052.2008.01733.x
-
N.A. Rao, M.E. van Wolferen, and R. van den Ham cDNA microarray profiles of canine mammary tumour cell lines reveal deregulated pathways pertaining to their phenotype Animal Genet 39 2008 333 345 (Pubitemid 351989267)
-
(2008)
Animal Genetics
, vol.39
, Issue.4
, pp. 333-345
-
-
Rao, N.A.S.1
Van Wolferen, M.E.2
Van Den Ham, R.3
Van Leenen, D.4
Groot Koerkamp, M.J.A.5
Holstege, F.C.P.6
Mol, J.A.7
-
32
-
-
10344258041
-
Targeting the mitogen-activated protein kinase cascade to treat cancer
-
DOI 10.1038/nrc1503
-
J.S. Sebolt-Leopold, and R. Herrera Targeting the mitogen-activated protein kinase cascade to treat cancer Nat Rev Cancer 4 2004 937 947 (Pubitemid 39626217)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.12
, pp. 937-947
-
-
Sebolt-Leopold, J.S.1
Herrera, R.2
-
33
-
-
0035175047
-
Clinical management of women with genomic BRCA1 and BRCA2 mutations
-
DOI 10.1023/A:1012203917104
-
J. Chang, and R.M. Elledge Clinical management of women with genomic BRCA1 and BRCA2 mutations Breast Cancer Res Treat 69 2001 101 113 (Pubitemid 33079017)
-
(2001)
Breast Cancer Research and Treatment
, vol.69
, Issue.2
, pp. 101-113
-
-
Chang, J.1
Elledge, R.M.2
-
34
-
-
0033575921
-
Overexpression of BRCA2 gene in sporadic breast tumours
-
DOI 10.1038/sj.onc.1202903
-
I. Biche, C. Nogus, and R. Lidereau Overexpression of BRCA2 gene in sporadic breast tumours Oncogene 18 1999 5232 5238 (Pubitemid 29460659)
-
(1999)
Oncogene
, vol.18
, Issue.37
, pp. 5232-5238
-
-
Bieche, I.1
Nogues, C.2
Lidereau, R.3
-
35
-
-
0034672182
-
Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer
-
H. Maacke, S. Opitz, and K. Jost Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer Int J Cancer 88 2000 907 913
-
(2000)
Int J Cancer
, vol.88
, pp. 907-913
-
-
Maacke, H.1
Opitz, S.2
Jost, K.3
-
36
-
-
0028950999
-
Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression
-
M.E. Thompson, R.A. Jensen, P.S. Obermiller, D.L. Page, and J.T. Holt Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression Nat Genet 9 1995 444 450
-
(1995)
Nat Genet
, vol.9
, pp. 444-450
-
-
Thompson, M.E.1
Jensen, R.A.2
Obermiller, P.S.3
Page, D.L.4
Holt, J.T.5
-
37
-
-
67649964356
-
Increased expression of BRCA2 and RAD51 in lymph node metastases of canine mammary Aden carcinomas
-
R. Klopfleisch, and A.D. Gruber Increased expression of BRCA2 and RAD51 in lymph node metastases of canine mammary Aden carcinomas Vet Pathol 46 2009 416 422
-
(2009)
Vet Pathol
, vol.46
, pp. 416-422
-
-
Klopfleisch, R.1
Gruber, A.D.2
-
38
-
-
0037623462
-
BRCA1 expression in canine mammary dysplasias and tumours: Relationship with prognostic variables
-
DOI 10.1053/jcpa.2002.0631
-
A. Nieto, M.D. Pérez-Alenza, and N. Del Castillo BRCA1 expression in canine mammary dysplasias and tumours: relationship with prognostic variables J Comp Pathol 128 2003 260 268 (Pubitemid 36531661)
-
(2003)
Journal of Comparative Pathology
, vol.128
, Issue.4
, pp. 260-268
-
-
Nieto, A.1
Perez-Alenza, M.D.2
Del Castillo, N.3
Tabanera, E.4
Castano, M.5
Pena, L.6
-
39
-
-
77950598697
-
Estrogens, regulation of p53 and breast cancer risk: A balancing act
-
D.J. Jerry, K.A. Dunphy, and M.J. Hagen Estrogens, regulation of p53 and breast cancer risk: a balancing act Cell Mol Life Sci 67 2010 1017 1023
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 1017-1023
-
-
Jerry, D.J.1
Dunphy, K.A.2
Hagen, M.J.3
-
40
-
-
67349130509
-
Differential expression of cell cycle regulators p21, p27 and p53 in metastasizing canine mammary adenocarcinomas versus normal mammary glands
-
R. Klopfleisch, and A.D. Gruber Differential expression of cell cycle regulators p21, p27 and p53 in metastasizing canine mammary adenocarcinomas versus normal mammary glands Res Vet Sci 87 2009 91 96
-
(2009)
Res Vet Sci
, vol.87
, pp. 91-96
-
-
Klopfleisch, R.1
Gruber, A.D.2
-
41
-
-
3042842752
-
Mutation and overexpression of p53 as a prognostic factor in canine mammary tumors
-
C.H. Lee, W.H. Kim, and J.H. Lim Mutation and overexpression of p53 as a prognostic factor in canine mammary tumors J Vet Sci 5 2004 63 69
-
(2004)
J Vet Sci
, vol.5
, pp. 63-69
-
-
Lee, C.H.1
Kim, W.H.2
Lim, J.H.3
-
42
-
-
0035292690
-
Aberrations of the p63 tumor suppressor gene in various tumors in dogs
-
A. Setoguchi, T. Sakai, and M. Okuda Aberrations of the p53 tumor suppressor gene in various tumors in dogs Am J Vet Res 62 2001 433 439 (Pubitemid 33605602)
-
(2001)
American Journal of Veterinary Research
, vol.62
, Issue.3
, pp. 433-439
-
-
Setoguchi, A.1
Sakai, T.2
Okuda, M.3
Minehata, K.4
Yazawa, M.5
Ishizaka, T.6
Watari, T.7
Nishimura, R.8
Sasaki, N.9
Hasegawa, A.10
Tsujimoto, H.11
-
44
-
-
33751530274
-
Steroid Receptors and Their Role in the Biology and Control of Breast Cancer Growth
-
DOI 10.1053/j.seminoncol.2006.08.020, PII S0093775406003319, Hormonal Therapy of Breast Cancer
-
F. Cordera, and V.C. Jordan Steroid receptors and their role in the biology and control of breast cancer growth Semin Oncol 33 2006 631 641 (Pubitemid 44834535)
-
(2006)
Seminars in Oncology
, vol.33
, Issue.6
, pp. 631-641
-
-
Cordera, F.1
Jordan, V.C.2
-
45
-
-
1542346452
-
The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer
-
DOI 10.1016/j.beem.2003.08.002
-
S.J. Howell, S.R. Johnston, and A. Howell The use of selective estrogen receptor modulators and selective estrogen receptor down regulators in breast cancer Best Pract Res Clin Endocrinol Metab 18 2004 47 66 (Pubitemid 38324626)
-
(2004)
Best Practice and Research: Clinical Endocrinology and Metabolism
, vol.18
, Issue.1
, pp. 47-66
-
-
Howell, S.J.1
Johnston, S.R.D.2
Howell, A.3
-
46
-
-
20444423824
-
A prospective analysis of immunohistochemically determined estrogen receptor α and progesterone receptor expression and host and tumor factors as predictors of disease-free period in mammary tumors of the dog
-
DOI 10.1354/vp.42-2-200
-
J.M. de Las Mulas, Y. Millán, and R. Dios A prospective analysis of immunohistochemically determined estrogen receptor alpha and progesterone receptor expression and host and tumor factors as predictors of disease-free period in mammary tumors of the dog Vet Pathol 42 2005 200 212 (Pubitemid 40797309)
-
(2005)
Veterinary Pathology
, vol.42
, Issue.2
, pp. 200-212
-
-
Martin De Las Mulas, J.1
Millan, Y.2
Dios, R.3
-
47
-
-
0034170019
-
Immunohistochemical study of hormonal receptors and cell proliferation in normal canine mammary glands and spontaneous mammary tumors
-
M. Geraldes, F. Gärtner, and F. Schmitt Immunohistochemical study of hormonal receptors and cell proliferation in normal canine mammary glands and spontaneous mammary tumors Vet Rec 146 2000 403 406
-
(2000)
Vet Rec
, vol.146
, pp. 403-406
-
-
Geraldes, M.1
Gärtner, F.2
Schmitt, F.3
-
48
-
-
0034186688
-
Immunohistologic detection of estrogen receptor alpha in canine mammary tumors: Clinical and pathologic associations and prognostic significance
-
A. Nieto, L. Peña, and M.D. Pérez-Alenza Immunohistologic detection of estrogen receptor alpha in canine mammary tumors: clinical and pathologic associations and prognostic significance Vet Pathol 37 2000 239 247
-
(2000)
Vet Pathol
, vol.37
, pp. 239-247
-
-
Nieto, A.1
Peña, L.2
Pérez-Alenza, M.D.3
-
49
-
-
68949159937
-
Molecular plasticity of E-cadherin and sialyl lewis x expression, in two comparative models of mammary tumorigenesis
-
S.S. Pinho, C.A. Reis, F. Gärtner, and M.L. Alpaugh Molecular plasticity of E-cadherin and sialyl lewis x expression, in two comparative models of mammary tumorigenesis PLoS One 4 2009 e6636
-
(2009)
PLoS One
, vol.4
, pp. 6636
-
-
Pinho, S.S.1
Reis, C.A.2
Gärtner, F.3
Alpaugh, M.L.4
-
50
-
-
65549123466
-
Molecular mechanisms controlling E-cadherin expression in breast cancer
-
S. Baranwal, and S.K. Alahari Molecular mechanisms controlling E-cadherin expression in breast cancer Biochem Biophys Res Commun 384 2009 6 11
-
(2009)
Biochem Biophys Res Commun
, vol.384
, pp. 6-11
-
-
Baranwal, S.1
Alahari, S.K.2
-
51
-
-
27744475329
-
Prognostic factors associated with survival two years after surgery in dogs with malignant mammary tumors: 79 cases (1998-2002)
-
S.C. Chang, C.C. Chang, T.J. Chang, and M.L. Wong Prognostic factors associated with survival two years after surgery in dogs with malignant mammary tumors: 79 cases (1998-2002) J Am Vet Med Assoc 227 2005 1625 1629
-
(2005)
J Am Vet Med Assoc
, vol.227
, pp. 1625-1629
-
-
Chang, S.C.1
Chang, C.C.2
Chang, T.J.3
Wong, M.L.4
-
52
-
-
0027349241
-
Prognostic factors in canine mammary tumors: A multivariate study of 202 consecutive cases
-
E. Hellmén, R. Bergström, and L. Holmberg Prognostic factors in canine mammary tumors: a multivariate study of 202 consecutive cases Vet Pathol 30 1993 20 27
-
(1993)
Vet Pathol
, vol.30
, pp. 20-27
-
-
Hellmén, E.1
Bergström, R.2
Holmberg, L.3
-
53
-
-
34248593582
-
E-cadherin, β-catenin, invasion and lymph node metastases in canine malignant mammary tumours
-
DOI 10.1111/j.1600-0463.2007.apm-544.x
-
A.J. De Matos, C.C. Lopes, and A.M. Faustino E-cadherin, beta-catenin, invasion and lymph node metastases in canine malignant mammary tumours APMIS 115 2007 327 334 (Pubitemid 46745228)
-
(2007)
APMIS
, vol.115
, Issue.4
, pp. 327-334
-
-
De Matos, A.J.F.1
Lopes, C.C.C.2
Faustino, A.M.R.3
Carvalheira, J.G.V.4
Rutteman, G.R.5
Gartner, M.D.F.R.M.6
-
54
-
-
44449140414
-
Expression of E-cadherin, P-cadherin and β-catenin in canine malignant mammary tumours in relation to clinicopathological parameters, proliferation and survival
-
DOI 10.1016/j.tvjl.2007.05.024, PII S1090023307002006
-
A. Gama, J. Paredes, F. Gärtner, A. Alves, and F. Schmitt Expression of E-cadherin, P-cadherin and beta-catenin in canine malignant mammary tumours in relation to clinicopathological parameters, proliferation and survival Vet J 117 2008 45 53 (Pubitemid 351753675)
-
(2008)
Veterinary Journal
, vol.177
, Issue.1
, pp. 45-53
-
-
Gama, A.1
Paredes, J.2
Gartner, F.3
Alves, A.4
Schmitt, F.5
-
55
-
-
33645891195
-
E-cadherin expression in canine malignant mammary tumours: Relationship to other clinico-pathological variables
-
A.J. Matos, C. Lopes, and J. Carvalheira E-cadherin expression in canine malignant mammary tumours: relationship to other clinico-pathological variables J Comp Pathol 134 2006 182 189
-
(2006)
J Comp Pathol
, vol.134
, pp. 182-189
-
-
Matos, A.J.1
Lopes, C.2
Carvalheira, J.3
-
57
-
-
23844489449
-
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation
-
DOI 10.1158/1078-0432.CCR-05-0059
-
J. Paredes, A. Albergaria, and J.T. Oliveira P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation Clin Cancer Res 11 2005 5869 5877 (Pubitemid 41170315)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.16
, pp. 5869-5877
-
-
Paredes, J.1
Albergaria, A.2
Oliveira, J.T.3
Jeronimo, C.4
Milanezi, F.5
Schmitt, F.C.6
-
58
-
-
0442326191
-
P-cadherin expression in canine mammary tissues
-
DOI 10.1016/S0021-9975(03)00064-1
-
A. Gama, J. Paredes, A. Albergaria, F. Gartner, and F. Schmitt P-cadherin expression in canine mammary tissues J Comp Pathol 130 2004 13 20 (Pubitemid 38185948)
-
(2004)
Journal of Comparative Pathology
, vol.130
, Issue.1
, pp. 13-20
-
-
Gama, A.1
Paredes, J.2
Albergaria, A.3
Gartner, F.4
Schmitt, F.5
-
59
-
-
77149180777
-
Epidermal growth factor receptor in triple-negative and basal-like breast cancer: Promising clinical target or only a marker?
-
M.L. Burness, T.A. Grushko, and O.I. Olopade Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker? Cancer J 16 2010 23 32
-
(2010)
Cancer J
, vol.16
, pp. 23-32
-
-
Burness, M.L.1
Grushko, T.A.2
Olopade, O.I.3
-
60
-
-
78449294111
-
EGFR signaling in breast cancer: Bad to the bone
-
J. Foley, N.K. Nickerson, and S. Nam EGFR signaling in breast cancer: bad to the bone Semin Cell Dev Biol 21 2010 951 960
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 951-960
-
-
Foley, J.1
Nickerson, N.K.2
Nam, S.3
-
61
-
-
70350270341
-
Immunohistochemical expression of Epidermal Growth Factor Receptor (EGFR) in canine mammary tissues
-
A. Gama, F. Gärtner, A. Alves, and F. Schmitt Immunohistochemical expression of Epidermal Growth Factor Receptor (EGFR) in canine mammary tissues Res Vet Sci 87 2009 432 437
-
(2009)
Res Vet Sci
, vol.87
, pp. 432-437
-
-
Gama, A.1
Gärtner, F.2
Alves, A.3
Schmitt, F.4
-
62
-
-
0027955913
-
Expression of epidermal growth factor receptor (EGFR) in non-affected and tumorous mammary tissue of female dogs
-
DOI 10.1007/BF00666057
-
G.R. Rutteman, J.A. Foekens, and H. Portengen Expression of epidermal growth factor receptor (EGFR) in non-affected and tumorous mammary tissue of female dogs Breast Cancer Res Treat 30 1994 139 146 (Pubitemid 24242665)
-
(1994)
Breast Cancer Research and Treatment
, vol.30
, Issue.2
, pp. 139-146
-
-
Rutteman, G.R.1
Foekens, J.A.2
Portengen, H.3
Vos, J.H.4
Blankenstein, M.A.5
Teske, E.6
Cronelisse, C.J.7
Misdorp, W.8
-
64
-
-
33846457870
-
Cancer statistics, 2007
-
A. Jemal, R. Siegel, and E. Ward Cancer statistics, 2007 CA Cancer J Clin 57 2007 43 66 (Pubitemid 46148091)
-
(2007)
Ca-A Cancer Journal for Clinicians
, vol.57
, Issue.1
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
65
-
-
0018571642
-
A comparative study of canine and human breast cancer
-
L.N. Owen A comparative study of canine and human breast cancer Invest Cell Pathol 2 1979 257 275 (Pubitemid 10172451)
-
(1979)
Investigative and Cell Pathology
, vol.2
, Issue.4
, pp. 257-275
-
-
Owen, L.N.1
-
67
-
-
16244367163
-
Modeling metastasis in vivo
-
DOI 10.1093/carcin/bgh261
-
C. Khanna, and HK Modeling metastasis in vivo Carcinogenesis 26 2005 513 523 (Pubitemid 41214139)
-
(2005)
Carcinogenesis
, vol.26
, Issue.3
, pp. 513-523
-
-
Khanna, C.1
Hunter, K.2
-
68
-
-
0037169354
-
Cancer susceptibility and the functions of BRCA1 and BRCA2
-
DOI 10.1016/S0092-8674(02)00615-3
-
A.R. Venkitaraman Cancer susceptibility and the functions of BRCA1 and BRCA2 Cell 108 2002 171 182 (Pubitemid 34161138)
-
(2002)
Cell
, vol.108
, Issue.2
, pp. 171-182
-
-
Venkitaraman, A.R.1
-
69
-
-
59349086106
-
P53 transcriptional activities: A general overview and some thoughts
-
J.F. Millau, N. Bastien, and R. Drouin P53 transcriptional activities: a general overview and some thoughts Mutat Res 681 2009 118 133
-
(2009)
Mutat Res
, vol.681
, pp. 118-133
-
-
Millau, J.F.1
Bastien, N.2
Drouin, R.3
-
70
-
-
34347357467
-
Using the canine genome to cure cancer and other diseases
-
DOI 10.1016/j.theriogenology.2007.04.016, PII S0093691X0700146X
-
P.N. Olson Using the canine genome to cure cancer and other diseases Theriogenology 68 2007 378 381 (Pubitemid 47017432)
-
(2007)
Theriogenology
, vol.68
, Issue.3
, pp. 378-381
-
-
Olson, P.N.1
-
71
-
-
69449100730
-
Evaluation of hormone receptor expression for use in predicting survival of female dogs with malignant mammary gland tumors
-
C.C. Chang, M.H. Tsai, and J.W. Liao Evaluation of hormone receptor expression for use in predicting survival of female dogs with malignant mammary gland tumors J Am Vet Med Assoc 235 2009 391 396
-
(2009)
J Am Vet Med Assoc
, vol.235
, pp. 391-396
-
-
Chang, C.C.1
Tsai, M.H.2
Liao, J.W.3
-
72
-
-
0036127795
-
Cellular expression of estrogen and progesterone receptors in mammary glands: Regulation by hormones, development and aging
-
DOI 10.1016/S0960-0760(01)00182-0, PII S0960076001001820
-
G. Shyamala, Y.C. Chou, and S.G. Louie Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging J Steroid Biochem Mol Biol 80 2002 137 148 (Pubitemid 34233736)
-
(2002)
Journal of Steroid Biochemistry and Molecular Biology
, vol.80
, Issue.2
, pp. 137-148
-
-
Shyamala, G.1
Chou, Y.-C.2
Louie, S.G.3
Guzman, R.C.4
Smith, G.H.5
Nandi, S.6
-
73
-
-
34547799601
-
Sialyl Lewis x expression in canine malignant mammary tumours: Correlation with clinicopathological features and E-Cadherin expression
-
S.S. Pinho, A.J. Matos, and C. Lopes Sialyl Lewis x expression in canine malignant mammary tumours: correlation with clinicopathological features and E-Cadherin expression BMC Cancer 7 2007 124
-
(2007)
BMC Cancer
, vol.7
, pp. 124
-
-
Pinho, S.S.1
Matos, A.J.2
Lopes, C.3
-
74
-
-
77957843649
-
Coordinated expression of galectin-3 and galectin-3-binding sites in malignant mammary tumors: Implications for tumor metastasis
-
J.T. de Oliveira, A.J. de Matos, and J. Gomes Coordinated expression of galectin-3 and galectin-3-binding sites in malignant mammary tumors: implications for tumor metastasis Glycobiology 20 2010 1341 1352
-
(2010)
Glycobiology
, vol.20
, pp. 1341-1352
-
-
De Oliveira, J.T.1
De Matos, A.J.2
Gomes, J.3
-
75
-
-
58949097354
-
Role of E-cadherin N-glycosylation profile in a mammary tumor model
-
S.S. Pinho, H. Osório, and M. Nita-Lazar Role of E-cadherin N-glycosylation profile in a mammary tumor model Biochem Biophys Res Commun 379 2009 1091 1096
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 1091-1096
-
-
Pinho, S.S.1
Osório, H.2
Nita-Lazar, M.3
-
77
-
-
70349437467
-
Guiding the optimal translation of new cancer treatments from canine to human cancer patients
-
C. Khanna, C. London, D. Vail, C. Mazcko, and S. Hirschfeld Guiding the optimal translation of new cancer treatments from canine to human cancer patients Clin Cancer Res 15 2009 5671 5677
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5671-5677
-
-
Khanna, C.1
London, C.2
Vail, D.3
Mazcko, C.4
Hirschfeld, S.5
-
78
-
-
38549112058
-
Translation of new cancer treatments from pet dogs to humans
-
DOI 10.1038/nrc2273, PII NRC2273
-
M. Paoloni, and C. Khanna Translation of new cancer treatments from pet dogs to humans Nat Rev Cancer 8 2008 147 156 (Pubitemid 351161319)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.2
, pp. 147-156
-
-
Paoloni, M.1
Khanna, C.2
-
79
-
-
32144458734
-
Clinical trials going to the dogs: Canine program to study tumor treatment, biology
-
G.S. Mack Clinical trials going to the dogs: canine program to study tumor treatment, biology J Natl Cancer Inst 98 2006 161 162
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 161-162
-
-
MacK, G.S.1
-
80
-
-
77649176523
-
Preclinical investigation of PEGylated tumor necrosis factor alpha in dogs with spontaneous tumors: Phase i evaluation
-
D.H. Thamm, I.D. Kurzman, and M.A. Clark Preclinical investigation of PEGylated tumor necrosis factor alpha in dogs with spontaneous tumors: phase I evaluation Clin Cancer Res 16 2010 1498 1508
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1498-1508
-
-
Thamm, D.H.1
Kurzman, I.D.2
Clark, M.A.3
-
81
-
-
12444319243
-
Phase I dose-escalating study of SU11654, a small molecule receptor tyrosine kinase inhibitor, in dogs with spontaneous malignancies
-
C.A. London, A.L. Hannah, and R. Zadovoskaya Phase I dose-escalating study of SU11654, a small molecule receptor tyrosine kinase inhibitor, in dogs with spontaneous malignancies Clin Cancer Res 9 2003 2755 2768 (Pubitemid 36842122)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.7
, pp. 2755-2768
-
-
London, C.A.1
Hannah, A.L.2
Zadovoskaya, R.3
Chien, M.B.4
Kollias-Baker, C.5
Rosenberg, M.6
Downing, S.7
Post, G.8
Boucher, J.9
Shenoy, N.10
Mendel, D.B.11
McMahon, G.12
Cherrington, J.M.13
-
82
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
A. Ullrich, and J. Schlessinger Signal transduction by receptors with tyrosine kinase activity Cell 61 1990 203 212
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
83
-
-
0035207448
-
The biology of signal transduction inhibition: Basic science to novel therapies
-
J. Griffin The biology of signal transduction inhibition: basic science to novel therapies Semin Oncol 28 2001 3 8 (Pubitemid 33140512)
-
(2001)
Seminars in Oncology
, vol.28
, Issue.5 SUPPL. 17
, pp. 3-8
-
-
Griffin, J.1
-
84
-
-
26244436314
-
Spontaneous tumours of pet dog as models for human cancers: Searching for adequate guidelines
-
G. De Vico, P. Maiolino, B. Restucci, and A. Passantino Spontaneous tumours of pet dog as models for human cancers: searching for adequate guidelines Riv Biol 98 2005 279 296 (Pubitemid 41412246)
-
(2005)
Rivista di Biologia - Biology Forum
, vol.98
, Issue.2
, pp. 279-296
-
-
De Vico, G.1
Maiolino, P.2
Restucci, B.3
Passantino, A.4
-
85
-
-
0028179763
-
Naturally occurring tumors in dogs as comparative models for cancer therapy research
-
K.A. Hahn, L. Bravo, W.H. Adams, and D.L. Frazier Naturally occurring tumors in dogs as comparative models for cancer therapy research In Vivo 8 1994 133 143 (Pubitemid 24156544)
-
(1994)
Vivo
, vol.8
, Issue.1
, pp. 133-143
-
-
Hahn, K.A.1
Bravo, L.2
Adams, W.H.3
Frazier, D.L.4
-
86
-
-
33646100285
-
Oncology of companion animals as a model for humans. an overview of tumor histotypes
-
A. Porrello, P. Cardelli, and E.P. Spugnini Oncology of companion animals as a model for humans. an overview of tumor histotypes J Exp Clin Cancer Res 25 2006 97 105
-
(2006)
J Exp Clin Cancer Res
, vol.25
, pp. 97-105
-
-
Porrello, A.1
Cardelli, P.2
Spugnini, E.P.3
-
87
-
-
70449091904
-
The Comparative Oncology Trials Consortium: Using spontaneously occurring cancers in dogs to inform the cancer drug development pathway
-
I. Gordon, M. Paoloni, C. Mazcko, and C. Khanna The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway PLoS Med 6 2009 e1000161
-
(2009)
PLoS Med
, vol.6
, pp. 1000161
-
-
Gordon, I.1
Paoloni, M.2
Mazcko, C.3
Khanna, C.4
|