Immunohistochemical study of hormonal receptors and cell proliferation in normal canine mammary glands and spontaneous mammary tumours

Veterinary Record

Volumn 146, Issue 14, 2000, Pages 403-406

  Geraldes, M ^a   Gartner F ^a   Schmitt, F ^a  

^a UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CANIS FAMILIARIS;

CELL SURFACE RECEPTOR;

ANIMAL; ARTICLE; CELL DIVISION; DOG; DOG DISEASE; EXPERIMENTAL NEOPLASM; FEMALE; ISOLATION AND PURIFICATION; PATHOLOGY; UDDER;

ANIMALS; CELL DIVISION; DOG DISEASES; DOGS; FEMALE; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; RECEPTORS, CELL SURFACE;

EID: 0034170019     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.146.14.403     Document Type: Article

References (28)

1. ALENZA, M. D. P., RUTTEMAN, G. R., KWIPENS-DIJKSOON, N. J., PENA, L., MONTOYA, A., MISDORP, W. & CORNELISSE, C. J. (1995) DNA flow cytometry of canine mammary tumours: the relationship of DNA ploidy and S-phase fraction to clinical and histological features. Research in Veterinary Science 58, 238-243
2. BAKER, V. A., PUDDEFOOT, J. R., MARSIDLIANTE, S., BARKER, S., GOODE, A. W. & VINSON, G. P. (1992) Oestrogen receptor isoforms, their distribution and relation to progesterone receptor levels in breast cancer samples. Journal of Cancer 66, 1083-1087
3. CHALBOS, D., PHILIPS, A. & ROCHEFORT, H. (1994) Genomic cross-talk between the estrogen receptor and growth factor regulatory pathways in estrogen target tissues. Seminars in Cancer Biology 5, 361-368
4. DESTEXHE, E., BIKER, E. & COIGNOUL, F. (1995) Image analysis evaluation of ploidy, S-phase fraction and nuclear area in canine mammary tumours. Journal of Comparative Pathology 113, 205-216
5. FRIERSON, H. F. (1991) Ploidy analysis and S-phase fraction determination by flow cytometry of invasive adenocarcinomas of the breast. American Journal of Surgical Pathology 15, 358-367
6. GERDES, J., LI, L., SCHLUETER, C., DUCHROW, M., WOHLENBERG, C., GERLACH, C., STAHMER, I., KLOTH, S., BRANDT, E. & FLAD, H. D. (1991) Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. American Journal of Pathology 138, 867-873
7. HAMPE, J. F. & MISDORP, W. (1974) Tumours and dysplasias of the mammary gland. Bulletin of the World Health Organization 50, 111-113
8. HELLMÉN, E., BERGSTROM, R., HOLMBERG, L., SPANGBERG, I. B., HANSON, K. & LINDGREN, A. (1993) Prognostic factors in canine mammary tumours: a multivariate study of 202 consecutive cases. Veterinary Pathology 30, 20-27
9. HSU, S. M., RAINE, L. & FANGER, H. (1981) The use of antividin antibody and avidin-biotin-peroxidase complex in immunoperoxidase technics. American Journal of Clinical Pathology 75, 816-821
10. HUANG, A., PETTIGREW, N. M. & WATSON, P. H. (1996) Immunohistochemical assay for oestrogen receptors in paraffin wax sections of breast carcinoma using a new monoclonal antibody. Journal of Pathology 180, 223-227
11. INABA, T., TAKAHASHI, N., MATSUDA, H. & IMON, T. (1984) Estrogen and progesterone receptors and progesterone metabolism in canine mammary tumours. Japanese Journal of Veterinary Science 46, 797-803
12. KWAPIEN, R. P., GILES, R. C., GEIL, R. G. & CASEY, H. W. (1980) Malignant mammary tumours in Beagle dogs dosed with investigational oral contraceptive steroid. Journal of National Cancer Institute 65, 137-144
13. MacEWEN, E. G., PATNAIK, A. K., HARVEY, H. J. & PANKO, W. B. (1982) Estrogen receptors in canine mammary tumours. Cancer Research 42, 2255-2259
14. MADEWELL, B. R. & THEILEN, G. H. (1987) Tumors of the mammary gland. In Veterinary Cancer Medicine. 2nd edn. Eds G. H. Theilin, B. R. Madewell. Philadelphia, Lea & Febiger. pp 327-344
15. MOULTON, J. E. (1990) Tumors of the mammary gland. In Tumors in Domestic Animals. 3rd edn. Ed J. E. Moulton. Berkeley, University of California Press, pp 518-552
16. PREZIOSI, R., SARLI, G., BENAZZI, C. & MARCATO, P. S. (1995) Detection of proliferating cell nuclear antigen (PCNA) in canine and feline mammary tumours. Journal of Comparative Pathology 113, 301-313
17. RUTTEMAN, G. R. (1990) Hormones and mammary tumour disease in the female dog: an update. In Vivo 4, 33-40
18. RUTTEMAN, G. R., CORNELISSE, C. J., DIJKSHOORN, N. J., POORTMAN, J. & MISDORP, W. (1988a) Flow cytometry analysis of DNA ploidy in canine mammary tumors. Cancer Research 48, 3411-3417
19. RUTTEMAN, G. R. & MISDORP, W. (1993) Hormonal background of canine and feline mammary tumors. Journal of Reproduction and Fertility 47, 483-487
20. RUTTEMAN, G. R., MISDORP, W., BLANTENSTEIN, M. A. & VAN DEN BROM, W. E. (1988b) Oestrogen (ER) and progestin receptors (PR) in mammary tissue of the female dog: different receptor profiles in non-malignant and malignant states. British Journal of Cancer 58, 594-599
21. SARTIN, E. A., BARNES, S., KWAPIEN, P. R. & WOLFE, L. G. (1992) Estrogen and progesterone receptor status of mammary carcinomas and correlation with clinical outcome in dogs. American Journal of Veterinary Research 53, 2196-2200
22. SCHMITT, F. C. (1995) Multistep progression from an oestrogen-dependent growth towards an autonomous growth in breast carcinogenesis. European Journal of Cancer 3IA, 2049-2052
23. SCHMITT, F. C. & FERREIRA, M. P. (1995) MIB-1 a suitable marker of proliferative activity in formalin-fixed, paraffin-embedded sections of breast cancer. International Journal of Surgical Pathology 2, 1-7
24. SCHMITT, F. C., PEREIRA, E. M., ANDRADE, L. M., TORRESAN, M. & DE LUCCA, L. (1994) The proliferating cell nuclear antigen index in breast carcinomas does not correlate with mitotic index and estrogen receptor immunoreactivity. Pathology Research and Practice 190, 786-791
25. SCHNEIDER, R., DOM, C. R. & TAYLOR, D. O. (1969) Factors influencing canine mammary cancer development and postsurgical survival. Journal of the National Cancer Institute 43, 1249-1261
26. TAHAN, S. R., NEUBERG, D. S., DIEFFENBACH, A. & YACOUB, L. (1993) Prediction of early relapse and shortened survival in patients with breast cancer by proliferating cell nuclear antigen score. Cancer 71, 3552-3559
27. TÊTU, B. & BRISSON, J. (1994) Prognostic significance of HER-2/neu onco-protein expression in node-positive breast cancer. The influence of the pattern of immunostaining and adjuvant therapy. Cancer 73, 2359-2365
28. WEIDNER, N., MOORE, J. & VARTANIAN, R. (1994) Correlation of Ki-67 antigen expression with mitotic figure index and tumor grade in breast carcinomas using the novel 'paraffin'-reactive MIB-1 antibody. Human Pathology 25, 337-342