-
1
-
-
34548562456
-
HER-2 therapy. HER-2/neu diagnostics in breast cancer
-
Carney W., Leitzel K., Ali S., Neumann R., Lipton A. HER-2 therapy. HER-2/neu diagnostics in breast cancer. Breast Cancer Res 2007, 9:207.
-
(2007)
Breast Cancer Res
, vol.9
, pp. 207
-
-
Carney, W.1
Leitzel, K.2
Ali, S.3
Neumann, R.4
Lipton, A.5
-
2
-
-
18344390418
-
ERBB receptors and cancer: the complexity of targeted inhibitors
-
Hynes N.E., Lane H.A. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005, 5:341-354.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
3
-
-
44149120446
-
HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer
-
Jones F.E. HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer. J Mammary Gland Biol Neoplasia 2008, 13:247-258.
-
(2008)
J Mammary Gland Biol Neoplasia
, vol.13
, pp. 247-258
-
-
Jones, F.E.1
-
4
-
-
34249275704
-
EGFR and HER-2 antagonists in breast cancer
-
O'Donovan N., Crown J. EGFR and HER-2 antagonists in breast cancer. Anticancer Res 2007, 27:1285-1294.
-
(2007)
Anticancer Res
, vol.27
, pp. 1285-1294
-
-
O'Donovan, N.1
Crown, J.2
-
5
-
-
2442701289
-
The ErbB/HER receptor protein-tyrosine kinases and cancer
-
Roskoski R. The ErbB/HER receptor protein-tyrosine kinases and cancer. Biochem Biophys Res Commun 2004, 319:1-11.
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 1-11
-
-
Roskoski, R.1
-
6
-
-
42449153652
-
HER2 therapy. Small molecule HER-2 tyrosine kinase inhibitors
-
Spector N., Xia W., El-Hariry I., Yarden Y., Bacus S. HER2 therapy. Small molecule HER-2 tyrosine kinase inhibitors. Breast Cancer Res 2007, 9:205.
-
(2007)
Breast Cancer Res
, vol.9
, pp. 205
-
-
Spector, N.1
Xia, W.2
El-Hariry, I.3
Yarden, Y.4
Bacus, S.5
-
7
-
-
44149087535
-
ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer
-
Stern D. ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer. J Mammary Gland Biol Neoplasia 2008, 13:215-223.
-
(2008)
J Mammary Gland Biol Neoplasia
, vol.13
, pp. 215-223
-
-
Stern, D.1
-
8
-
-
44149089008
-
Role of ErbB4 in breast cancer
-
Sundvall M., Iljin K., Kilpinen S., Sara H., Kallioniemi O.P., Elenius K. Role of ErbB4 in breast cancer. J Mammary Gland Biol Neoplasia 2008, 13:259-268.
-
(2008)
J Mammary Gland Biol Neoplasia
, vol.13
, pp. 259-268
-
-
Sundvall, M.1
Iljin, K.2
Kilpinen, S.3
Sara, H.4
Kallioniemi, O.P.5
Elenius, K.6
-
9
-
-
0036081784
-
The expression of EGFR family ligands in breast carcinomas
-
Suo Z., Risberg B., Karlsson M.G., Villman K., Skovlund E., Nesland J.M. The expression of EGFR family ligands in breast carcinomas. Int J Surg Pathol 2002, 10:91-99.
-
(2002)
Int J Surg Pathol
, vol.10
, pp. 91-99
-
-
Suo, Z.1
Risberg, B.2
Karlsson, M.G.3
Villman, K.4
Skovlund, E.5
Nesland, J.M.6
-
10
-
-
0036164390
-
Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer
-
Tsutsui S., Ohno S., Murakami S., Hachitanda Y., Oda S. Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer. Breast Cancer Res Treat 2002, 71:67-75.
-
(2002)
Breast Cancer Res Treat
, vol.71
, pp. 67-75
-
-
Tsutsui, S.1
Ohno, S.2
Murakami, S.3
Hachitanda, Y.4
Oda, S.5
-
11
-
-
34447306848
-
Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer
-
Valabrega G., Montemurro F., Aglietta M. Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer. Ann Oncol 2007, 18:977-984.
-
(2007)
Ann Oncol
, vol.18
, pp. 977-984
-
-
Valabrega, G.1
Montemurro, F.2
Aglietta, M.3
-
12
-
-
44449127592
-
The epidermal growth factor receptor family: biology driving targeted therapeutics
-
Wieduwilt M.J., Moasser M.M. The epidermal growth factor receptor family: biology driving targeted therapeutics. Cell Mol Life Sci 2008, 65:1566-1584.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1566-1584
-
-
Wieduwilt, M.J.1
Moasser, M.M.2
-
13
-
-
21644438384
-
The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches
-
Zaczek A., Brandt B., Bielawski K.P. The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches. Histol Histopathol 2005, 20:1005-1015.
-
(2005)
Histol Histopathol
, vol.20
, pp. 1005-1015
-
-
Zaczek, A.1
Brandt, B.2
Bielawski, K.P.3
-
14
-
-
77649095719
-
HER3 comes of age: new insights into its functions and role in signaling, tumor biology, and cancer therapy
-
Campbell M.R., Amin D., Moasser M.M. HER3 comes of age: new insights into its functions and role in signaling, tumor biology, and cancer therapy. Clin Cancer Res 2010, 16:1373-1383.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1373-1383
-
-
Campbell, M.R.1
Amin, D.2
Moasser, M.M.3
-
15
-
-
48649092620
-
A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy
-
Lee-Hoeflich S.T., Crocker L., Yao E., Pham T., Munroe X., Hoeflich K.P., et al. A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy. Cancer Res 2008, 68:5878-5887.
-
(2008)
Cancer Res
, vol.68
, pp. 5878-5887
-
-
Lee-Hoeflich, S.T.1
Crocker, L.2
Yao, E.3
Pham, T.4
Munroe, X.5
Hoeflich, K.P.6
-
16
-
-
0031936410
-
Specificity within the EGF family/ErbB receptor family signaling network
-
Riese D.J., Stern D.F. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998, 20:41-48.
-
(1998)
Bioessays
, vol.20
, pp. 41-48
-
-
Riese, D.J.1
Stern, D.F.2
-
17
-
-
63049100044
-
Functional selectivity of EGF family peptide growth factors: implications for cancer
-
Wilson K.J., Gilmore J.L., Foley J., Lemmon M.A., Riese D.J. Functional selectivity of EGF family peptide growth factors: implications for cancer. Pharmacol Ther 2009, 122:1-8.
-
(2009)
Pharmacol Ther
, vol.122
, pp. 1-8
-
-
Wilson, K.J.1
Gilmore, J.L.2
Foley, J.3
Lemmon, M.A.4
Riese, D.J.5
-
18
-
-
78449278703
-
EGFR may couple moderate alcohol consumption to increased breast cancer risk
-
Mill C.P., Chester J.A., Riese D.J. EGFR may couple moderate alcohol consumption to increased breast cancer risk. Breast Cancer (London) 2009, 2009:31-38.
-
(2009)
Breast Cancer (London)
, vol.2009
, pp. 31-38
-
-
Mill, C.P.1
Chester, J.A.2
Riese, D.J.3
-
19
-
-
33745714456
-
ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors
-
Ohtsu H., Dempsey P.J., Eguchi S. ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors. Am J Physiol Cell Physiol 2006, 291:C1-C10.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Ohtsu, H.1
Dempsey, P.J.2
Eguchi, S.3
-
20
-
-
33646249825
-
TACE-dependent EGF receptor activation in angiotensin-II-induced kidney disease
-
Shah B.H., Catt K.J. TACE-dependent EGF receptor activation in angiotensin-II-induced kidney disease. Trends Pharmacol Sci 2006, 27:235-237.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 235-237
-
-
Shah, B.H.1
Catt, K.J.2
-
21
-
-
38449087529
-
Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer
-
Bhola N.E., Grandis J.R. Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer. Front Biosci 2008, 13:1857-1865.
-
(2008)
Front Biosci
, vol.13
, pp. 1857-1865
-
-
Bhola, N.E.1
Grandis, J.R.2
-
22
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
Daub H., Weiss F.U., Wallasch C., Ullrich A. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996, 379:557-560.
-
(1996)
Nature
, vol.379
, pp. 557-560
-
-
Daub, H.1
Weiss, F.U.2
Wallasch, C.3
Ullrich, A.4
-
23
-
-
0033103843
-
Processing and juxtacrine activity of membrane-anchored betacellulin
-
Tada H., Sasada R., Kawaguchi Y., Kojima I., Gullick W.J., Salomon D.S., et al. Processing and juxtacrine activity of membrane-anchored betacellulin. J Cell Biochem 1999, 72:423-434.
-
(1999)
J Cell Biochem
, vol.72
, pp. 423-434
-
-
Tada, H.1
Sasada, R.2
Kawaguchi, Y.3
Kojima, I.4
Gullick, W.J.5
Salomon, D.S.6
-
24
-
-
0025779606
-
Membrane-anchored forms of EGF stimulate focus formation and intercellular communication
-
Dobashi Y., Stern D.F. Membrane-anchored forms of EGF stimulate focus formation and intercellular communication. Oncogene 1991, 6:1151-1159.
-
(1991)
Oncogene
, vol.6
, pp. 1151-1159
-
-
Dobashi, Y.1
Stern, D.F.2
-
25
-
-
19644373566
-
The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode
-
Dong J., Opresko L.K., Chrisler W., Orr G., Quesenberry R.D., Lauffenburger D.A., et al. The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode. Mol Biol Cell 2005, 16:2984-2998.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 2984-2998
-
-
Dong, J.1
Opresko, L.K.2
Chrisler, W.3
Orr, G.4
Quesenberry, R.D.5
Lauffenburger, D.A.6
-
26
-
-
34250216633
-
Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis
-
Riese D.J., Gallo R.M., Settleman J. Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis. Bioessays 2007, 29:558-565.
-
(2007)
Bioessays
, vol.29
, pp. 558-565
-
-
Riese, D.J.1
Gallo, R.M.2
Settleman, J.3
-
27
-
-
62649159075
-
Ligand-induced ErbB receptor dimerization
-
Lemmon M.A. Ligand-induced ErbB receptor dimerization. Exp Cell Res 2009, 315:638-648.
-
(2009)
Exp Cell Res
, vol.315
, pp. 638-648
-
-
Lemmon, M.A.1
-
28
-
-
33746905531
-
Phosphotyrosine interactome of the ErbB-receptor kinase family
-
Schulze W.X., Deng L., Mann M. Phosphotyrosine interactome of the ErbB-receptor kinase family. Mol Syst Biol 2005, 1:0008.
-
(2005)
Mol Syst Biol
, vol.1
, pp. 0008
-
-
Schulze, W.X.1
Deng, L.2
Mann, M.3
-
29
-
-
77953896432
-
Cell signaling by receptor tyrosine kinases
-
Lemmon M.A., Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2010, 141:1117-1134.
-
(2010)
Cell
, vol.141
, pp. 1117-1134
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
30
-
-
0029889579
-
Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif
-
Sorkin A., Mazzotti M., Sorkina T., Scotto L., Beguinot L. Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif. J Biol Chem 1996, 271:13377-13384.
-
(1996)
J Biol Chem
, vol.271
, pp. 13377-13384
-
-
Sorkin, A.1
Mazzotti, M.2
Sorkina, T.3
Scotto, L.4
Beguinot, L.5
-
31
-
-
0032544418
-
Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signaling
-
Keilhack H., Tenev T., Nyakatura E., Godovac-Zimmermann J., Nielsen L., Seedorf K., et al. Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signaling. J Biol Chem 1998, 273:24839-24846.
-
(1998)
J Biol Chem
, vol.273
, pp. 24839-24846
-
-
Keilhack, H.1
Tenev, T.2
Nyakatura, E.3
Godovac-Zimmermann, J.4
Nielsen, L.5
Seedorf, K.6
-
32
-
-
0031041185
-
Both SH2 domains are involved in interaction of SHP-1 with the epidermal growth factor receptor but cannot confer receptor-directed activity to SHP-1/SHP-2 chimera
-
Tenev T., Keilhack H., Tomic S., Stoyanov B., Stein-Gerlach M., Lammers R., et al. Both SH2 domains are involved in interaction of SHP-1 with the epidermal growth factor receptor but cannot confer receptor-directed activity to SHP-1/SHP-2 chimera. J Biol Chem 1997, 272:5966-5973.
-
(1997)
J Biol Chem
, vol.272
, pp. 5966-5973
-
-
Tenev, T.1
Keilhack, H.2
Tomic, S.3
Stoyanov, B.4
Stein-Gerlach, M.5
Lammers, R.6
-
33
-
-
0029021518
-
Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research
-
Earp H.S., Dawson T.L., Li X., Yu H. Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research. Breast Cancer Res Treat 1995, 35:115-132.
-
(1995)
Breast Cancer Res Treat
, vol.35
, pp. 115-132
-
-
Earp, H.S.1
Dawson, T.L.2
Li, X.3
Yu, H.4
-
34
-
-
0025194462
-
Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function
-
Wada T., Qian X.L., Greene M.I. Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function. Cell 1990, 61:1339-1347.
-
(1990)
Cell
, vol.61
, pp. 1339-1347
-
-
Wada, T.1
Qian, X.L.2
Greene, M.I.3
-
35
-
-
0030783917
-
Reduced ability of transforming growth factor-alpha to induce EGF receptor heterodimerization and downregulation suggests a mechanism of oncogenic synergy with ErbB2
-
Gulliford T.J., Huang G.C., Ouyang X., Epstein R.J. Reduced ability of transforming growth factor-alpha to induce EGF receptor heterodimerization and downregulation suggests a mechanism of oncogenic synergy with ErbB2. Oncogene 1997, 15:2219-2223.
-
(1997)
Oncogene
, vol.15
, pp. 2219-2223
-
-
Gulliford, T.J.1
Huang, G.C.2
Ouyang, X.3
Epstein, R.J.4
-
36
-
-
0032948524
-
Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation
-
Wang Z., Zhang L., Yeung T.K., Chen X. Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation. Mol Biol Cell 1999, 10:1621-1636.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1621-1636
-
-
Wang, Z.1
Zhang, L.2
Yeung, T.K.3
Chen, X.4
-
37
-
-
0141530936
-
HER2-mediated effects on EGFR endosomal sorting: analysis of biophysical mechanisms
-
Hendriks B.S., Wiley H.S., Lauffenburger D. HER2-mediated effects on EGFR endosomal sorting: analysis of biophysical mechanisms. Biophys J 2003, 85:2732-2745.
-
(2003)
Biophys J
, vol.85
, pp. 2732-2745
-
-
Hendriks, B.S.1
Wiley, H.S.2
Lauffenburger, D.3
-
38
-
-
46949099486
-
Amphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells
-
Gilmore J.L., Scott J.A., Bouizar Z., Robling A., Pitfield S.E., Riese D.J., et al. Amphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells. Breast Cancer Res Treat 2008, 110:493-505.
-
(2008)
Breast Cancer Res Treat
, vol.110
, pp. 493-505
-
-
Gilmore, J.L.1
Scott, J.A.2
Bouizar, Z.3
Robling, A.4
Pitfield, S.E.5
Riese, D.J.6
-
39
-
-
0032217156
-
C-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
-
Levkowitz G., Waterman H., Zamir E., Kam Z., Oved S., Langdon W.Y., et al. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev 1998, 12:3663-3674.
-
(1998)
Genes Dev
, vol.12
, pp. 3663-3674
-
-
Levkowitz, G.1
Waterman, H.2
Zamir, E.3
Kam, Z.4
Oved, S.5
Langdon, W.Y.6
-
40
-
-
41149086227
-
EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate
-
Stern K.A., Place T.L., Lill N.L. EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate. Biochem J 2008, 410:585-594.
-
(2008)
Biochem J
, vol.410
, pp. 585-594
-
-
Stern, K.A.1
Place, T.L.2
Lill, N.L.3
-
41
-
-
57649240411
-
Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop
-
Willmarth N.E., Baillo A., Dziubinski M.L., Wilson K., Riese D.J., Ethier S.P. Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop. Cell Signal 2009, 21:212-219.
-
(2009)
Cell Signal
, vol.21
, pp. 212-219
-
-
Willmarth, N.E.1
Baillo, A.2
Dziubinski, M.L.3
Wilson, K.4
Riese, D.J.5
Ethier, S.P.6
-
42
-
-
72449168516
-
Reconstitution of amphiregulin-epidermal growth factor receptor signaling in lung squamous cell carcinomas activates PTHrP gene expression and contributes to cancer-mediated diseases of the bone
-
Gilmore J.L., Gonterman R.M., Menon K., Lorch G., Riese D.J., Robling A. Reconstitution of amphiregulin-epidermal growth factor receptor signaling in lung squamous cell carcinomas activates PTHrP gene expression and contributes to cancer-mediated diseases of the bone. Mol Cancer Res 2009, 7:1714-1728.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1714-1728
-
-
Gilmore, J.L.1
Gonterman, R.M.2
Menon, K.3
Lorch, G.4
Riese, D.J.5
Robling, A.6
-
43
-
-
36249012382
-
EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation
-
Joslin E.J., Opresko L.K., Wells A., Wiley H.S., Lauffenburger D.A. EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation. J Cell Sci 2007, 120:3688-3699.
-
(2007)
J Cell Sci
, vol.120
, pp. 3688-3699
-
-
Joslin, E.J.1
Opresko, L.K.2
Wells, A.3
Wiley, H.S.4
Lauffenburger, D.A.5
-
44
-
-
0027225188
-
Expression of epidermal growth factor receptor (proto-oncogene c-erbB-1) and estrogen receptor in human breast carcinoma. An immunocytochemical study of 70 cases
-
Garcia Castro C., Ravina M., Castro V., Salido E.C. Expression of epidermal growth factor receptor (proto-oncogene c-erbB-1) and estrogen receptor in human breast carcinoma. An immunocytochemical study of 70 cases. Arch Gynecol Obstet 1993, 252:169-177.
-
(1993)
Arch Gynecol Obstet
, vol.252
, pp. 169-177
-
-
Garcia Castro, C.1
Ravina, M.2
Castro, V.3
Salido, E.C.4
-
45
-
-
0027421819
-
Epidermal growth factor receptor immunohistochemistry in different histological types of infiltrating breast carcinoma
-
Martinazzi M., Crivelli F., Zampatti C., Martinazzi S. Epidermal growth factor receptor immunohistochemistry in different histological types of infiltrating breast carcinoma. J Clin Pathol 1993, 46:1009-1010.
-
(1993)
J Clin Pathol
, vol.46
, pp. 1009-1010
-
-
Martinazzi, M.1
Crivelli, F.2
Zampatti, C.3
Martinazzi, S.4
-
46
-
-
0029065071
-
Immunohistochemical assay for epidermal growth factor receptor on paraffin-embedded sections: validation against ligand-binding assay and clinical relevance in breast cancer
-
Newby J.C., A'Hern R.P., Leek R.D., Smith I.E., Harris A.L., Dowsett M. Immunohistochemical assay for epidermal growth factor receptor on paraffin-embedded sections: validation against ligand-binding assay and clinical relevance in breast cancer. Br J Cancer 1995, 71:1237-1242.
-
(1995)
Br J Cancer
, vol.71
, pp. 1237-1242
-
-
Newby, J.C.1
A'Hern, R.P.2
Leek, R.D.3
Smith, I.E.4
Harris, A.L.5
Dowsett, M.6
-
47
-
-
0030748009
-
Epidermal growth factor receptor-immunohistochemical detection and clinical significance for treatment of primary breast cancer
-
Schroeder W., Biesterfeld S., Zillessen S., Rath W. Epidermal growth factor receptor-immunohistochemical detection and clinical significance for treatment of primary breast cancer. Anticancer Res 1997, 17:2799-2802.
-
(1997)
Anticancer Res
, vol.17
, pp. 2799-2802
-
-
Schroeder, W.1
Biesterfeld, S.2
Zillessen, S.3
Rath, W.4
-
48
-
-
0034948188
-
Epidermal growth factor receptor expression in 780 breast cancer patients: a reappraisal of the prognostic value based on an eight-year median follow-up
-
Ferrero J.M., Ramaioli A., Largillier R., Formento J.L., Francoual M., Ettore F., et al. Epidermal growth factor receptor expression in 780 breast cancer patients: a reappraisal of the prognostic value based on an eight-year median follow-up. Ann Oncol 2001, 12:841-846.
-
(2001)
Ann Oncol
, vol.12
, pp. 841-846
-
-
Ferrero, J.M.1
Ramaioli, A.2
Largillier, R.3
Formento, J.L.4
Francoual, M.5
Ettore, F.6
-
49
-
-
0033747558
-
Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay
-
Pawlowski V., Revillion F., Hebbar M., Hornez L., Peyrat J.P. Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay. Clin Cancer Res 2000, 6:4217-4225.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4217-4225
-
-
Pawlowski, V.1
Revillion, F.2
Hebbar, M.3
Hornez, L.4
Peyrat, J.P.5
-
50
-
-
0034869383
-
Expression of amphiregulin and epidermal growth factor receptor in human breast cancer: analysis of autocriny and stromal-epithelial interactions
-
Ma L., de Roquancourt A., Bertheau P., Chevret S., Millot G., Sastre-Garau X., et al. Expression of amphiregulin and epidermal growth factor receptor in human breast cancer: analysis of autocriny and stromal-epithelial interactions. J Pathol 2001, 194:413-419.
-
(2001)
J Pathol
, vol.194
, pp. 413-419
-
-
Ma, L.1
de Roquancourt, A.2
Bertheau, P.3
Chevret, S.4
Millot, G.5
Sastre-Garau, X.6
-
51
-
-
0034076920
-
Expression of TGF-alpha and EGFR in breast cancer and its relation to angiogenesis
-
Soares R., Pereira M.B., Silva C., Amendoeira I., Wagner R., Ferro J., et al. Expression of TGF-alpha and EGFR in breast cancer and its relation to angiogenesis. Breast J 2000, 6:171-177.
-
(2000)
Breast J
, vol.6
, pp. 171-177
-
-
Soares, R.1
Pereira, M.B.2
Silva, C.3
Amendoeira, I.4
Wagner, R.5
Ferro, J.6
-
52
-
-
4043121142
-
Clinical relevance of amphiregulin and VEGF in primary breast cancers
-
Desruisseau S., Palmari J., Giusti C., Romain S., Martin P.M., Berthois Y. Clinical relevance of amphiregulin and VEGF in primary breast cancers. Int J Cancer 2004, 111:733-740.
-
(2004)
Int J Cancer
, vol.111
, pp. 733-740
-
-
Desruisseau, S.1
Palmari, J.2
Giusti, C.3
Romain, S.4
Martin, P.M.5
Berthois, Y.6
-
53
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer L.J., Dai H., van de Vijver M.J., He Y.D., Hart A.A., Mao M., et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002, 415:530-536.
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
van't Veer, L.J.1
Dai, H.2
van de Vijver, M.J.3
He, Y.D.4
Hart, A.A.5
Mao, M.6
-
54
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver M.J., He Y.D., van't Veer L.J., Dai H., Hart A.A., Voskuil D.W., et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002, 347:1999-2009.
-
(2002)
N Engl J Med
, vol.347
, pp. 1999-2009
-
-
van de Vijver, M.J.1
He, Y.D.2
van't Veer, L.J.3
Dai, H.4
Hart, A.A.5
Voskuil, D.W.6
-
55
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T., Perou C.M., Tibshirani R., Aas T., Geisler S., Johnsen H., et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001, 98:10869-10874.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
-
57
-
-
43549104712
-
Basal carcinoma of the breast revisited: an old entity with new interpretations
-
Korsching E., Jeffrey S.S., Meinerz W., Decker T., Boecker W., Buerger H. Basal carcinoma of the breast revisited: an old entity with new interpretations. J Clin Pathol 2008, 61:553-560.
-
(2008)
J Clin Pathol
, vol.61
, pp. 553-560
-
-
Korsching, E.1
Jeffrey, S.S.2
Meinerz, W.3
Decker, T.4
Boecker, W.5
Buerger, H.6
-
58
-
-
77149180777
-
Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker?
-
Burness M.L., Grushko T.A., Olopade O.I. Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker?. Cancer J 2010, 16:23-32.
-
(2010)
Cancer J
, vol.16
, pp. 23-32
-
-
Burness, M.L.1
Grushko, T.A.2
Olopade, O.I.3
-
59
-
-
13844310310
-
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
-
Wang Y., Klijn J.G., Zhang Y., Sieuwerts A.M., Look M.P., Yang F., et al. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 2005, 365:671-679.
-
(2005)
Lancet
, vol.365
, pp. 671-679
-
-
Wang, Y.1
Klijn, J.G.2
Zhang, Y.3
Sieuwerts, A.M.4
Look, M.P.5
Yang, F.6
-
60
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn A.J., Gupta G.P., Siegel P.M., Bos P.D., Shu W., Giri D.D., et al. Genes that mediate breast cancer metastasis to lung. Nature 2005, 436:518-524.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
-
61
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos P.D., Zhang X.H., Nadal C., Shu W., Gomis R.R., Nguyen D.X., et al. Genes that mediate breast cancer metastasis to the brain. Nature 2009, 459:1005-1009.
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
Zhang, X.H.2
Nadal, C.3
Shu, W.4
Gomis, R.R.5
Nguyen, D.X.6
-
62
-
-
67649211199
-
Invasive ductal carcinoma of the breast with the " triple-negative" phenotype: prognostic implications of EGFR immunoreactivity
-
Viale G., Rotmensz N., Maisonneuve P., Bottiglieri L., Montagna E., Luini A., et al. Invasive ductal carcinoma of the breast with the " triple-negative" phenotype: prognostic implications of EGFR immunoreactivity. Breast Cancer Res Treat 2009, 116:317-328.
-
(2009)
Breast Cancer Res Treat
, vol.116
, pp. 317-328
-
-
Viale, G.1
Rotmensz, N.2
Maisonneuve, P.3
Bottiglieri, L.4
Montagna, E.5
Luini, A.6
-
63
-
-
33846817495
-
Targeting TACE-dependent EGFR ligand shedding in breast cancer
-
Kenny P.A., Bissell M.J. Targeting TACE-dependent EGFR ligand shedding in breast cancer. J Clin Invest 2007, 117:337-345.
-
(2007)
J Clin Invest
, vol.117
, pp. 337-345
-
-
Kenny, P.A.1
Bissell, M.J.2
-
64
-
-
34248353890
-
Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development
-
Ciarloni L., Mallepell S., Brisken C. Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development. Proc Natl Acad Sci USA 2007, 104:5455-5460.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5455-5460
-
-
Ciarloni, L.1
Mallepell, S.2
Brisken, C.3
-
65
-
-
4444307857
-
Expressional regulation of neuronal and cancer-related genes by estrogen in adult female rats
-
Rho J.Y., Wada-Kiyama Y., Onishi Y., Kiyama R., Sakuma Y. Expressional regulation of neuronal and cancer-related genes by estrogen in adult female rats. Endocr Res 2004, 30:257-267.
-
(2004)
Endocr Res
, vol.30
, pp. 257-267
-
-
Rho, J.Y.1
Wada-Kiyama, Y.2
Onishi, Y.3
Kiyama, R.4
Sakuma, Y.5
-
66
-
-
33645234316
-
Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth
-
Britton D.J., Hutcheson I.R., Knowlden J.M., Barrow D., Giles M., McClelland R.A., et al. Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. Breast Cancer Res Treat 2006, 96:131-146.
-
(2006)
Breast Cancer Res Treat
, vol.96
, pp. 131-146
-
-
Britton, D.J.1
Hutcheson, I.R.2
Knowlden, J.M.3
Barrow, D.4
Giles, M.5
McClelland, R.A.6
-
67
-
-
66449117772
-
Mechanisms of resistance to structurally diverse antiestrogens differ under premenopausal and postmenopausal conditions: evidence from in vitro breast cancer cell models
-
Fan P., Yue W., Wang J.P., Aiyar S., Li Y., Kim T.H., et al. Mechanisms of resistance to structurally diverse antiestrogens differ under premenopausal and postmenopausal conditions: evidence from in vitro breast cancer cell models. Endocrinology 2009, 150:2036-2045.
-
(2009)
Endocrinology
, vol.150
, pp. 2036-2045
-
-
Fan, P.1
Yue, W.2
Wang, J.P.3
Aiyar, S.4
Li, Y.5
Kim, T.H.6
-
68
-
-
37649007431
-
Selective estrogen-receptor modulators and antihormonal resistance in breast cancer
-
Jordan V.C., O'Malley B.W. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol 2007, 25:5815-5824.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5815-5824
-
-
Jordan, V.C.1
O'Malley, B.W.2
-
69
-
-
63649117164
-
Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells
-
Santen R.J., Fan P., Zhang Z., Bao Y., Song R.X., Yue W. Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells. Steroids 2009, 74:586-594.
-
(2009)
Steroids
, vol.74
, pp. 586-594
-
-
Santen, R.J.1
Fan, P.2
Zhang, Z.3
Bao, Y.4
Song, R.X.5
Yue, W.6
-
70
-
-
33846207899
-
Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant
-
Fan M., Yan P.S., Hartman-Frey C., Chen L., Paik H., Oyer S.L., et al. Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Res 2006, 66:11954-11966.
-
(2006)
Cancer Res
, vol.66
, pp. 11954-11966
-
-
Fan, M.1
Yan, P.S.2
Hartman-Frey, C.3
Chen, L.4
Paik, H.5
Oyer, S.L.6
-
71
-
-
59449093537
-
Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant
-
Frogne T., Benjaminsen R.V., Sonne-Hansen K., Sorensen B.S., Nexo E., Laenkholm A.V., et al. Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant. Breast Cancer Res Treat 2009, 114:263-275.
-
(2009)
Breast Cancer Res Treat
, vol.114
, pp. 263-275
-
-
Frogne, T.1
Benjaminsen, R.V.2
Sonne-Hansen, K.3
Sorensen, B.S.4
Nexo, E.5
Laenkholm, A.V.6
-
72
-
-
58149380742
-
Stem cell concepts renew cancer research
-
Dick J.E. Stem cell concepts renew cancer research. Blood 2008, 112:4793-4807.
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
73
-
-
60149109533
-
Looking ahead in cancer stem cell research
-
Dick J.E. Looking ahead in cancer stem cell research. Nat Biotechnol 2009, 27:44-46.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 44-46
-
-
Dick, J.E.1
-
74
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003, 100:3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
75
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C., Hur M.H., Charafe-Jauffret E., Monville F., Dutcher J., Brown M., et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007, 1:555-567.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
Monville, F.4
Dutcher, J.5
Brown, M.6
-
76
-
-
60549111070
-
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
-
Charafe-Jauffret E., Ginestier C., Iovino F., Wicinski J., Cervera N., Finetti P., et al. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 2009, 69:1302-1313.
-
(2009)
Cancer Res
, vol.69
, pp. 1302-1313
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Iovino, F.3
Wicinski, J.4
Cervera, N.5
Finetti, P.6
-
77
-
-
34247581697
-
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways
-
Farnie G., Clarke R.B., Spence K., Pinnock N., Brennan K., Anderson N.G., et al. Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst 2007, 99:616-627.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 616-627
-
-
Farnie, G.1
Clarke, R.B.2
Spence, K.3
Pinnock, N.4
Brennan, K.5
Anderson, N.G.6
-
78
-
-
54049096261
-
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
-
Korkaya H., Paulson A., Iovino F., Wicha M.S. HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 2008, 27:6120-6130.
-
(2008)
Oncogene
, vol.27
, pp. 6120-6130
-
-
Korkaya, H.1
Paulson, A.2
Iovino, F.3
Wicha, M.S.4
-
79
-
-
44449117461
-
Lapatinib study supports cancer stem cell hypothesis, encourages industry research
-
Schmidt C. Lapatinib study supports cancer stem cell hypothesis, encourages industry research. J Natl Cancer Inst 2008, 100:694-695.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 694-695
-
-
Schmidt, C.1
-
82
-
-
0023145358
-
Survival from first recurrence: relative importance of prognostic factors in 1,015 breast cancer patients
-
Clark G.M., Sledge G.W., Osborne C.K., McGuire W.L. Survival from first recurrence: relative importance of prognostic factors in 1,015 breast cancer patients. J Clin Oncol 1987, 5:55-61.
-
(1987)
J Clin Oncol
, vol.5
, pp. 55-61
-
-
Clark, G.M.1
Sledge, G.W.2
Osborne, C.K.3
McGuire, W.L.4
-
83
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
Zhang X.H., Wang Q., Gerald W., Hudis C.A., Norton L., Smid M., et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 2009, 16:67-78.
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
Wang, Q.2
Gerald, W.3
Hudis, C.A.4
Norton, L.5
Smid, M.6
-
84
-
-
0032491037
-
Reduction in new metastases in breast cancer with adjuvant clodronate treatment
-
Diel I.J., Solomayer E.F., Costa S.D., Gollan C., Goerner R., Wallwiener D., et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med 1998, 339:357-363.
-
(1998)
N Engl J Med
, vol.339
, pp. 357-363
-
-
Diel, I.J.1
Solomayer, E.F.2
Costa, S.D.3
Gollan, C.4
Goerner, R.5
Wallwiener, D.6
-
85
-
-
63049090100
-
Metastasis: from dissemination to organ-specific colonization
-
Nguyen D.X., Bos P.D., Massague J. Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 2009, 9:274-284.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
86
-
-
0036160735
-
Metastatic breast cancer with HER2/neu-positive cells tends to have a morbid prognosis
-
Emi Y., Kitamura K., Shikada Y., Kakeji Y., Takahashi I., Tsutsui S. Metastatic breast cancer with HER2/neu-positive cells tends to have a morbid prognosis. Surgery 2002, 131:S217-S221.
-
(2002)
Surgery
, vol.131
-
-
Emi, Y.1
Kitamura, K.2
Shikada, Y.3
Kakeji, Y.4
Takahashi, I.5
Tsutsui, S.6
-
87
-
-
51649120140
-
Review: biological relevance of disseminated tumor cells in cancer patients
-
Riethdorf S., Wikman H., Pantel K. Review: biological relevance of disseminated tumor cells in cancer patients. Int J Cancer 2008, 123:1991-2006.
-
(2008)
Int J Cancer
, vol.123
, pp. 1991-2006
-
-
Riethdorf, S.1
Wikman, H.2
Pantel, K.3
-
88
-
-
52049099136
-
Tumor cell dormancy: implications for the biology and treatment of breast cancer
-
Fehm T., Mueller V., Marches R., Klein G., Gueckel B., Neubauer H., et al. Tumor cell dormancy: implications for the biology and treatment of breast cancer. Apmis 2008, 116:742-753.
-
(2008)
Apmis
, vol.116
, pp. 742-753
-
-
Fehm, T.1
Mueller, V.2
Marches, R.3
Klein, G.4
Gueckel, B.5
Neubauer, H.6
-
89
-
-
52049116094
-
Cancer micrometastasis and tumour dormancy
-
Wikman H., Vessella R., Pantel K. Cancer micrometastasis and tumour dormancy. Apmis 2008, 116:754-770.
-
(2008)
Apmis
, vol.116
, pp. 754-770
-
-
Wikman, H.1
Vessella, R.2
Pantel, K.3
-
90
-
-
33750306612
-
Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
-
Balic M., Lin H., Young L., Hawes D., Giuliano A., McNamara G., et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res 2006, 12:5615-5621.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5615-5621
-
-
Balic, M.1
Lin, H.2
Young, L.3
Hawes, D.4
Giuliano, A.5
McNamara, G.6
-
91
-
-
0035266243
-
ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients
-
Braun S., Schlimok G., Heumos I., Schaller G., Riethdorf L., Riethmuller G., et al. ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients. Cancer Res 2001, 61:1890-1895.
-
(2001)
Cancer Res
, vol.61
, pp. 1890-1895
-
-
Braun, S.1
Schlimok, G.2
Heumos, I.3
Schaller, G.4
Riethdorf, L.5
Riethmuller, G.6
-
92
-
-
0027235985
-
Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells
-
Pantel K., Schlimok G., Braun S., Kutter D., Lindemann F., Schaller G., et al. Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells. J Natl Cancer Inst 1993, 85:1419-1424.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1419-1424
-
-
Pantel, K.1
Schlimok, G.2
Braun, S.3
Kutter, D.4
Lindemann, F.5
Schaller, G.6
-
93
-
-
0033305222
-
Breast cancer cells interact with osteoblasts to support osteoclast formation
-
Thomas R.J., Guise T.A., Yin J.J., Elliott J., Horwood N.J., Martin T.J., et al. Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology 1999, 140:4451-4458.
-
(1999)
Endocrinology
, vol.140
, pp. 4451-4458
-
-
Thomas, R.J.1
Guise, T.A.2
Yin, J.J.3
Elliott, J.4
Horwood, N.J.5
Martin, T.J.6
-
94
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve R.M., Chin K., Fridlyand J., Yeh J., Baehner F.L., Fevr T., et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006, 10:515-527.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
-
95
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y., Siegel P.M., Shu W., Drobnjak M., Kakonen S.M., Cordon-Cardo C., et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003, 3:537-549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
-
96
-
-
33750738067
-
Basic mechanisms responsible for osteolytic and osteoblastic bone metastases
-
Guise T.A., Mohammad K.S., Clines G., Stebbins E.G., Wong D.H., Higgins L.S., et al. Basic mechanisms responsible for osteolytic and osteoblastic bone metastases. Clin Cancer Res 2006, 12:6213s-6216s.
-
(2006)
Clin Cancer Res
, vol.12
-
-
Guise, T.A.1
Mohammad, K.S.2
Clines, G.3
Stebbins, E.G.4
Wong, D.H.5
Higgins, L.S.6
-
97
-
-
70349108389
-
Breaking down bone: new insight into site-specific mechanisms of breast cancer osteolysis mediated by metalloproteinases
-
Guise T.A. Breaking down bone: new insight into site-specific mechanisms of breast cancer osteolysis mediated by metalloproteinases. Genes Dev 2009, 23:2117-2123.
-
(2009)
Genes Dev
, vol.23
, pp. 2117-2123
-
-
Guise, T.A.1
-
98
-
-
44349152371
-
Increased COX2 expression enhances tumor-induced osteoclastic lesions in breast cancer bone metastasis
-
Li Z., Schem C., Shi Y., Medina D., Zhang M. Increased COX2 expression enhances tumor-induced osteoclastic lesions in breast cancer bone metastasis. Clin Exp Metastasis 2007, 25:389-400.
-
(2007)
Clin Exp Metastasis
, vol.25
, pp. 389-400
-
-
Li, Z.1
Schem, C.2
Shi, Y.3
Medina, D.4
Zhang, M.5
-
99
-
-
0036792257
-
Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo
-
Bendre M.S., Gaddy-Kurten D., Mon-Foote T., Akel N.S., Skinner R.A., Nicholas R.W., et al. Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. Cancer Res 2002, 62:5571-5579.
-
(2002)
Cancer Res
, vol.62
, pp. 5571-5579
-
-
Bendre, M.S.1
Gaddy-Kurten, D.2
Mon-Foote, T.3
Akel, N.S.4
Skinner, R.A.5
Nicholas, R.W.6
-
100
-
-
0032918414
-
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
Yin J.J., Selander K., Chirgwin J.M., Dallas M., Grubbs B.G., Wieser R., et al. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest 1999, 103:197-206.
-
(1999)
J Clin Invest
, vol.103
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
Grubbs, B.G.5
Wieser, R.6
-
101
-
-
0029177030
-
EGF receptor expression in mineralized tissues: an in situ hybridization and immunocytochemical investigation in rat and human mandibles
-
Davideau J.L., Sahlberg C., Thesleff I., Berdal A. EGF receptor expression in mineralized tissues: an in situ hybridization and immunocytochemical investigation in rat and human mandibles. Connect Tissue Res 1995, 32:47-53.
-
(1995)
Connect Tissue Res
, vol.32
, pp. 47-53
-
-
Davideau, J.L.1
Sahlberg, C.2
Thesleff, I.3
Berdal, A.4
-
102
-
-
0020957321
-
Epidermal growth factor receptors in clonal lines of a rat osteogenic sarcoma and in osteoblast-rich rat bone cells
-
Ng K.W., Partridge N.C., Niall M., Martin T.J. Epidermal growth factor receptors in clonal lines of a rat osteogenic sarcoma and in osteoblast-rich rat bone cells. Calcif Tissue Int 1983, 35:298-303.
-
(1983)
Calcif Tissue Int
, vol.35
, pp. 298-303
-
-
Ng, K.W.1
Partridge, N.C.2
Niall, M.3
Martin, T.J.4
-
103
-
-
0027293701
-
The combined effect of tumor-produced parathyroid hormone-related protein and transforming growth factor-alpha enhance hypercalcemia in vivo and bone resorption in vitro
-
Guise T.A., Yoneda T., Yates A.J., Mundy G.R. The combined effect of tumor-produced parathyroid hormone-related protein and transforming growth factor-alpha enhance hypercalcemia in vivo and bone resorption in vitro. J Clin Endocrinol Metab 1993, 77:40-45.
-
(1993)
J Clin Endocrinol Metab
, vol.77
, pp. 40-45
-
-
Guise, T.A.1
Yoneda, T.2
Yates, A.J.3
Mundy, G.R.4
-
104
-
-
0020613199
-
Tumor-derived growth factor increases bone resorption in a tumor associated with humoral hypercalcemia of malignancy
-
Ibbotson K.J., D'Souza S.M., Ng K.W., Osborne C.K., Niall M., Martin T.J., et al. Tumor-derived growth factor increases bone resorption in a tumor associated with humoral hypercalcemia of malignancy. Science 1983, 221:1292-1294.
-
(1983)
Science
, vol.221
, pp. 1292-1294
-
-
Ibbotson, K.J.1
D'Souza, S.M.2
Ng, K.W.3
Osborne, C.K.4
Niall, M.5
Martin, T.J.6
-
105
-
-
0021948260
-
EGF receptor antiserum inhibits bone resorbing activity produced by a rat Leydig cell tumor associated with the humoral hypercalcemia of malignancy
-
Ibbotson K.J., D'Souza S.M., Smith D.D., Carpenter G., Mundy G.R. EGF receptor antiserum inhibits bone resorbing activity produced by a rat Leydig cell tumor associated with the humoral hypercalcemia of malignancy. Endocrinology 1985, 116:469-471.
-
(1985)
Endocrinology
, vol.116
, pp. 469-471
-
-
Ibbotson, K.J.1
D'Souza, S.M.2
Smith, D.D.3
Carpenter, G.4
Mundy, G.R.5
-
106
-
-
34848827653
-
EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors by osteoblasts: implications for osteolytic bone metastases
-
Zhu J., Jia X., Xiao G., Kang Y., Partridge N.C., Qin L. EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors by osteoblasts: implications for osteolytic bone metastases. J Biol Chem 2007, 282:26656-26664.
-
(2007)
J Biol Chem
, vol.282
, pp. 26656-26664
-
-
Zhu, J.1
Jia, X.2
Xiao, G.3
Kang, Y.4
Partridge, N.C.5
Qin, L.6
-
107
-
-
21244450719
-
Gefitinib inhibits the ability of human bone marrow stromal cells to induce osteoclast differentiation: implications for the pathogenesis and treatment of bone metastasis
-
Normanno N., De Luca A., Aldinucci D., Maiello M.R., Mancino M., D'Antonio A., et al. Gefitinib inhibits the ability of human bone marrow stromal cells to induce osteoclast differentiation: implications for the pathogenesis and treatment of bone metastasis. Endocr Relat Cancer 2005, 12:471-482.
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 471-482
-
-
Normanno, N.1
De Luca, A.2
Aldinucci, D.3
Maiello, M.R.4
Mancino, M.5
D'Antonio, A.6
-
108
-
-
0038165507
-
Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics
-
Qin L., Qiu P., Wang L., Li X., Swarthout J.T., Soteropoulos P., et al. Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics. J Biol Chem 2003, 278:19723-19731.
-
(2003)
J Biol Chem
, vol.278
, pp. 19723-19731
-
-
Qin, L.1
Qiu, P.2
Wang, L.3
Li, X.4
Swarthout, J.T.5
Soteropoulos, P.6
-
109
-
-
27144445950
-
Stimulation of amphiregulin expression in osteoblastic cells by parathyroid hormone requires the protein kinase A and cAMP response element-binding protein signaling pathway
-
Qin L., Partridge N.C. Stimulation of amphiregulin expression in osteoblastic cells by parathyroid hormone requires the protein kinase A and cAMP response element-binding protein signaling pathway. J Cell Biochem 2005, 96:632-640.
-
(2005)
J Cell Biochem
, vol.96
, pp. 632-640
-
-
Qin, L.1
Partridge, N.C.2
-
110
-
-
0033305424
-
Parathyroid hormone activates mitogen-activated protein kinase in opossum kidney cells
-
Cole J.A. Parathyroid hormone activates mitogen-activated protein kinase in opossum kidney cells. Endocrinology 1999, 140:5771-5779.
-
(1999)
Endocrinology
, vol.140
, pp. 5771-5779
-
-
Cole, J.A.1
-
111
-
-
10144241022
-
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
-
Guise T.A., Yin J.J., Taylor S.D., Kumagai Y., Dallas M., Boyce B.F., et al. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J Clin Invest 1996, 98:1544-1549.
-
(1996)
J Clin Invest
, vol.98
, pp. 1544-1549
-
-
Guise, T.A.1
Yin, J.J.2
Taylor, S.D.3
Kumagai, Y.4
Dallas, M.5
Boyce, B.F.6
-
112
-
-
0025674602
-
Immunohistochemical localization of parathyroid hormone-related protein in human breast cancer
-
Southby J., Kissin M.W., Danks J.A., Hayman J.A., Moseley J.M., Henderson M.A., et al. Immunohistochemical localization of parathyroid hormone-related protein in human breast cancer. Cancer Res 1990, 50:7710-7716.
-
(1990)
Cancer Res
, vol.50
, pp. 7710-7716
-
-
Southby, J.1
Kissin, M.W.2
Danks, J.A.3
Hayman, J.A.4
Moseley, J.M.5
Henderson, M.A.6
-
113
-
-
0025821071
-
Localization of parathyroid hormone-related protein in breast cancer metastases: increased incidence in bone compared with other sites
-
Powell G.J., Southby J., Danks J.A., Stillwell R.G., Hayman J.A., Henderson M.A., et al. Localization of parathyroid hormone-related protein in breast cancer metastases: increased incidence in bone compared with other sites. Cancer Res 1991, 51:3059-3061.
-
(1991)
Cancer Res
, vol.51
, pp. 3059-3061
-
-
Powell, G.J.1
Southby, J.2
Danks, J.A.3
Stillwell, R.G.4
Hayman, J.A.5
Henderson, M.A.6
-
114
-
-
0035819528
-
Parathyroid hormone-related protein production by breast cancers, improved survival, and reduced bone metastases
-
Henderson M., Danks J., Moseley J., Slavin J., Harris T., McKinlay M., et al. Parathyroid hormone-related protein production by breast cancers, improved survival, and reduced bone metastases. J Natl Cancer Inst 2001, 93:234-237.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 234-237
-
-
Henderson, M.1
Danks, J.2
Moseley, J.3
Slavin, J.4
Harris, T.5
McKinlay, M.6
-
115
-
-
0026667477
-
Localization of parathyroid hormone-related protein mRNA expression in breast cancer and metastatic lesions by in situ hybridization
-
Vargas S.J., Gillespie M.T., Powell G.J., Southby J., Danks J.A., Moseley J.M., et al. Localization of parathyroid hormone-related protein mRNA expression in breast cancer and metastatic lesions by in situ hybridization. J Bone Miner Res 1992, 7:971-979.
-
(1992)
J Bone Miner Res
, vol.7
, pp. 971-979
-
-
Vargas, S.J.1
Gillespie, M.T.2
Powell, G.J.3
Southby, J.4
Danks, J.A.5
Moseley, J.M.6
-
116
-
-
2342647462
-
Regulation of parathyroid hormone-related protein gene expression by epidermal growth factor-family ligands in primary human keratinocytes
-
Cho Y.M., Lewis D.A., Koltz P.F., Richard V., Gocken T.A., Rosol T.J., et al. Regulation of parathyroid hormone-related protein gene expression by epidermal growth factor-family ligands in primary human keratinocytes. J Endocrinol 2004, 181:179-190.
-
(2004)
J Endocrinol
, vol.181
, pp. 179-190
-
-
Cho, Y.M.1
Lewis, D.A.2
Koltz, P.F.3
Richard, V.4
Gocken, T.A.5
Rosol, T.J.6
-
117
-
-
34447301304
-
Inhibition of epidermal growth factor receptor signalling reduces hypercalcaemia induced by human lung squamous-cell carcinoma in athymic mice
-
Lorch G., Gilmore J.L., Koltz P.F., Gonterman R.M., Laughner R., Lewis D.A., et al. Inhibition of epidermal growth factor receptor signalling reduces hypercalcaemia induced by human lung squamous-cell carcinoma in athymic mice. Br J Cancer 2007, 97:183-193.
-
(2007)
Br J Cancer
, vol.97
, pp. 183-193
-
-
Lorch, G.1
Gilmore, J.L.2
Koltz, P.F.3
Gonterman, R.M.4
Laughner, R.5
Lewis, D.A.6
-
119
-
-
46949099486
-
Amphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells
-
Gilmore J.L., Scott J.A., Bouizar Z., Robling A., Pitfield S.E., Riese D.J., et al. Amphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells. Breast Cancer Res Treat 2007, 110:493-505.
-
(2007)
Breast Cancer Res Treat
, vol.110
, pp. 493-505
-
-
Gilmore, J.L.1
Scott, J.A.2
Bouizar, Z.3
Robling, A.4
Pitfield, S.E.5
Riese, D.J.6
-
120
-
-
69249228553
-
ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis
-
Lu X., Wang Q., Hu G., Van Poznak C., Fleisher M., Reiss M., et al. ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes Dev 2009, 23:1882-1894.
-
(2009)
Genes Dev
, vol.23
, pp. 1882-1894
-
-
Lu, X.1
Wang, Q.2
Hu, G.3
Van Poznak, C.4
Fleisher, M.5
Reiss, M.6
-
121
-
-
2942716892
-
Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism
-
MacLeod J.R., Yano S., Chattopadhyay N., Brown E.M. Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism. Biochem Biophys Res Commun 2004, 320:455-460.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 455-460
-
-
MacLeod, J.R.1
Yano, S.2
Chattopadhyay, N.3
Brown, E.M.4
-
122
-
-
0038581051
-
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
-
Gschwind A., Hart S., Fischer O.M., Ullrich A. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J 2003, 22:2411-2421.
-
(2003)
EMBO J
, vol.22
, pp. 2411-2421
-
-
Gschwind, A.1
Hart, S.2
Fischer, O.M.3
Ullrich, A.4
-
123
-
-
72749111836
-
Target-based therapies in breast cancer: current status and future perspectives
-
Normanno N., Morabito A., De Luca A., Piccirillo M.C., Gallo M., Maiello M.R., et al. Target-based therapies in breast cancer: current status and future perspectives. Endocr Relat Cancer 2009, 16:675-702.
-
(2009)
Endocr Relat Cancer
, vol.16
, pp. 675-702
-
-
Normanno, N.1
Morabito, A.2
De Luca, A.3
Piccirillo, M.C.4
Gallo, M.5
Maiello, M.R.6
-
124
-
-
0042675500
-
Open-label, phase II, multicenter trial of ZD1839 ('Iressa') in patients with advanced breast cancer
-
Albain K.S., Elledge R., Gradishar W.J., Hayes D.F., Rowinsky E., Hudis C., et al. Open-label, phase II, multicenter trial of ZD1839 ('Iressa') in patients with advanced breast cancer. Breast Cancer Res Treat 2002, 76:S33.
-
(2002)
Breast Cancer Res Treat
, vol.76
-
-
Albain, K.S.1
Elledge, R.2
Gradishar, W.J.3
Hayes, D.F.4
Rowinsky, E.5
Hudis, C.6
-
125
-
-
20844456577
-
A multicentre phase II study on gefitinib in taxane- and anthracycline-pretreated metastatic breast cancer
-
von Minckwitz G., Jonat W., Fasching P., du Bois A., Kleeberg U., Luck H.J., et al. A multicentre phase II study on gefitinib in taxane- and anthracycline-pretreated metastatic breast cancer. Breast Cancer Res Treat 2005, 89:165-172.
-
(2005)
Breast Cancer Res Treat
, vol.89
, pp. 165-172
-
-
von Minckwitz, G.1
Jonat, W.2
Fasching, P.3
du Bois, A.4
Kleeberg, U.5
Luck, H.J.6
-
126
-
-
77949754385
-
Phase II, randomized trial to compare anastrozole combined with gefitinib or placebo in postmenopausal women with hormone receptor-positive metastatic breast cancer
-
Cristofanilli M., Valero V., Mangalik A., Royce M., Rabinowitz I., Arena F.P., et al. Phase II, randomized trial to compare anastrozole combined with gefitinib or placebo in postmenopausal women with hormone receptor-positive metastatic breast cancer. Clin Cancer Res 2010, 16:1904-1914.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1904-1914
-
-
Cristofanilli, M.1
Valero, V.2
Mangalik, A.3
Royce, M.4
Rabinowitz, I.5
Arena, F.P.6
-
127
-
-
77649173208
-
Lapatinib restores hormone sensitivity with differential effects on estrogen receptor signaling in cell models of human epidermal growth factor receptor 2-negative breast cancer with acquired endocrine resistance
-
Leary A.F., Drury S., Detre S., Pancholi S., Lykkesfeldt A.E., Martin L.A., et al. Lapatinib restores hormone sensitivity with differential effects on estrogen receptor signaling in cell models of human epidermal growth factor receptor 2-negative breast cancer with acquired endocrine resistance. Clin Cancer Res 2010, 16:1486-1497.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1486-1497
-
-
Leary, A.F.1
Drury, S.2
Detre, S.3
Pancholi, S.4
Lykkesfeldt, A.E.5
Martin, L.A.6
-
128
-
-
73149115341
-
Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer
-
Johnston S., Pippen J., Pivot X., Lichinitser M., Sadeghi S., Dieras V., et al. Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer. J Clin Oncol 2009, 27:5538-5546.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5538-5546
-
-
Johnston, S.1
Pippen, J.2
Pivot, X.3
Lichinitser, M.4
Sadeghi, S.5
Dieras, V.6
|