-
1
-
-
49349111218
-
Targeting Her-2/neu in breast cancer: As easy as this!
-
Azim H, Azim HA Jr: Targeting Her-2/neu in breast cancer: as easy as this! Oncology 74:150-157, 2008
-
(2008)
Oncology
, vol.74
, pp. 150-157
-
-
Azim, H.1
Azim Jr, H.A.2
-
2
-
-
0036279974
-
Reduced expression of PTEN correlates with breast cancer progression
-
Bose S, Crane A, Hibshoosh H, Mansukhani M, Sandweis L, Parsons R: Reduced expression of PTEN correlates with breast cancer progression. Hum Pathol 33:405-409, 2002
-
(2002)
Hum Pathol
, vol.33
, pp. 405-409
-
-
Bose, S.1
Crane, A.2
Hibshoosh, H.3
Mansukhani, M.4
Sandweis, L.5
Parsons, R.6
-
3
-
-
0034729805
-
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: Evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1
-
Bruni P, Boccia A, Baldassarre G, Trapasso F, Santoro M, Chiappetta G, Fusco A, Viglietto G: PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1. Oncogene 19:3146-3155, 2000
-
(2000)
Oncogene
, vol.19
, pp. 3146-3155
-
-
Bruni, P.1
Boccia, A.2
Baldassarre, G.3
Trapasso, F.4
Santoro, M.5
Chiappetta, G.6
Fusco, A.7
Viglietto, G.8
-
4
-
-
43749120732
-
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications
-
Carnero A, Blanco-Aparicio C, Renner O, Link W, Leal JF: The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. Curr Cancer Drug Targets 8:187-198, 2008
-
(2008)
Curr Cancer Drug Targets
, vol.8
, pp. 187-198
-
-
Carnero, A.1
Blanco-Aparicio, C.2
Renner, O.3
Link, W.4
Leal, J.F.5
-
5
-
-
0031727881
-
Tumour grading and the one-year post-surgical prognosis in feline mammary carcinomas
-
Castagnaro M, Casalone C, Bozzetta E, De Maria R, Biolatti B, Caramelli M: Tumour grading and the one-year post-surgical prognosis in feline mammary carcinomas. J Comp Path 119:263-275, 1998
-
(1998)
J Comp Path
, vol.119
, pp. 263-275
-
-
Castagnaro, M.1
Casalone, C.2
Bozzetta, E.3
de Maria, R.4
Biolatti, B.5
Caramelli, M.6
-
6
-
-
0031613621
-
A study of the PTEN/MMAC1 gene in 136 breast cancer families
-
Chen J, Lindblom P, Lindblom A: A study of the PTEN/MMAC1 gene in 136 breast cancer families. Hum Genet 102:124-125, 1998
-
(1998)
Hum Genet
, vol.102
, pp. 124-125
-
-
Chen, J.1
Lindblom, P.2
Lindblom, A.3
-
7
-
-
0033856110
-
PTEN, a unique tumor suppressor gene
-
Dahia PL: PTEN, a unique tumor suppressor gene. Endocr Relat Cancer 7:115-129, 2000
-
(2000)
Endocr Relat Cancer
, vol.7
, pp. 115-129
-
-
Dahia, P.L.1
-
8
-
-
0034920457
-
Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer
-
Depowski PL, Rosenthal SI, Ross JS: Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer. Mod Pathol 14:672-676, 2001
-
(2001)
Mod Pathol
, vol.14
, pp. 672-676
-
-
Depowski, P.L.1
Rosenthal, S.I.2
Ross, J.S.3
-
9
-
-
0034681264
-
The multiple roles of PTEN in tumor suppression
-
Di Cristofano A, Pandolfi PP: The multiple roles of PTEN in tumor suppression. Cell 100:387-390, 2000
-
(2000)
Cell
, vol.100
, pp. 387-390
-
-
di Cristofano, A.1
Pandolfi, P.P.2
-
10
-
-
24644509362
-
Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma
-
Dickerson EB, Thomas R, Fosmire SP, Lamerato-Kozicki AR, Bianco SR, Wojcieszyn JW, Breen M, Helfand SC, Modiano JF: Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma. Vet Pathol 42:618-632, 2005
-
(2005)
Vet Pathol
, vol.42
, pp. 618-632
-
-
Dickerson, E.B.1
Thomas, R.2
Fosmire, S.P.3
Lamerato-Kzicki, A.R.4
Bianco, S.R.5
Wojcieszyn, J.W.6
Breen, M.7
Helfand, S.C.8
Modiano, J.F.9
-
11
-
-
0026072872
-
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
-
republished Histopathology 41: 154-161, 2002
-
Elston CW, Ellis IO: Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19:403-410, 1991; republished Histopathology 41: 154-161, 2002
-
(1991)
Histopathology
, vol.19
, pp. 403-410
-
-
Elston, C.W.1
Ellis, I.O.2
-
12
-
-
0033003079
-
Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma
-
Feilotter HE, Coulon V, McVeigh JL, Boag AH, Dorion-Bonnet F, Duboue B, Latham WC, Eng C, Mulligan LM, Longy M: Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma. Br J Cancer 79:718-723, 1999
-
(1999)
Br J Cancer
, vol.79
, pp. 718-723
-
-
Feilotter, H.E.1
Coulon, V.2
McVeigh, J.L.3
Boag, A.H.4
Dorion-Bonnet, F.5
Duboue, B.6
Latham, W.C.7
Eng, C.8
Mulligan, L.M.9
Longy, M.10
-
13
-
-
0033636096
-
Survival analysis in clinical trials: Past developments and future directions
-
Fleming TR, Lin DY: Survival analysis in clinical trials: past developments and future directions. Biometrics 56:971-983, 2000
-
(2000)
Biometrics
, vol.56
, pp. 971-983
-
-
Fleming, T.R.1
Lin, D.Y.2
-
14
-
-
0041450058
-
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
-
Freeman DJ, Li AG, Wei G, Li HH, Kertesz N, Lesche R, Whale AD, Martinez-Diaz H, Rozengurt N, Cardiff RD, Liu X, Wu H: PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell 3:117-130, 2003
-
(2003)
Cancer Cell
, vol.3
, pp. 117-130
-
-
Freeman, D.J.1
Li, A.G.2
Wei, G.3
Li, H.H.4
Kertesz, N.5
Lesche, R.6
Whale, A.D.7
Martinez-Diaz, H.8
Rozengurt, N.9
Cardiff, R.D.10
Liu, X.11
Wu, H.12
-
15
-
-
0032804162
-
Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype
-
Garcia JM, Silva JM, Dominguez G, Gonzalez R, Navarro A, Carretero L, Provencio M, España P, Bonilla F: Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype. Breast Cancer Res Treat 57:237-243, 1999
-
(1999)
Breast Cancer Res Treat
, vol.57
, pp. 237-243
-
-
Garcia, J.M.1
Silva, J.M.2
Dominguez, G.3
Gonzalez, R.4
Navarro, A.5
Carretero, L.6
Provencio, M.7
España, P.8
Bonilla, F.9
-
16
-
-
51849098272
-
Drug discovery approaches targeting the PI3K/Akt pathway in cancer
-
Garcia-Echeverria C, Sellers WR: Drug discovery approaches targeting the PI3K/Akt pathway in cancer. Oncogene 27:5511-5526, 2008
-
(2008)
Oncogene
, vol.27
, pp. 5511-5526
-
-
Garcia-Echeverria, C.1
Sellers, W.R.2
-
17
-
-
33645221622
-
Expression of the PTEN tumor sup-pressor gene in malignant mammary gland tumors of dogs
-
Kanae Y, Endoh D, Yokota H, Taniyama H, Hayashi M: Expression of the PTEN tumor sup-pressor gene in malignant mammary gland tumors of dogs. Am J Vet Res 67:127-133, 2006
-
(2006)
Am J Vet Res
, vol.67
, pp. 127-133
-
-
Kanae, Y.1
Endoh, D.2
Yokota, H.3
Taniyama, H.4
Hayashi, M.5
-
18
-
-
27944487083
-
Histological grading and prognosis in dogs with mammary carcinomas: Application of a human grading method
-
Karayannopoulou M, Kaldrymidou E, Constantinidis TC, Dessiris A: Histological grading and prognosis in dogs with mammary carcinomas: application of a human grading method. J Comp Pathol 133:246-252, 2005
-
(2005)
J Comp Pathol
, vol.133
, pp. 246-252
-
-
Karayannopoulou, M.1
Kaldrymidou, E.2
Constantinidis, T.C.3
Dessiris, A.4
-
19
-
-
0036637521
-
Expression and significance of p53, rb, p21/waf-1, p16/ink-4a, and PTEN tumor suppressors in canine melanoma
-
Koenig A, Bianco SR, Fosmire S, Wojcieszyn J, Modiano JF: Expression and significance of p53, rb, p21/waf-1, p16/ink-4a, and PTEN tumor suppressors in canine melanoma. Vet Pathol 39:458-472, 2002
-
(2002)
Vet Pathol
, vol.39
, pp. 458-472
-
-
Koenig, A.1
Bianco, S.R.2
Fosmire, S.3
Wojcieszyn, J.4
Modiano, J.F.5
-
20
-
-
0035945352
-
The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
-
Kotelevets L, van HJ, Bruyneel E, Mareel M, van RF, Chastre E: The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness. J Cell Biol 155: 1129-1135, 2001
-
(2001)
J Cell Biol
, vol.155
, pp. 1129-1135
-
-
Kotelevets, L.1
van, H.J.2
Bruyneel, E.3
Mareel, M.4
van, R.F.5
Chastre, E.6
-
21
-
-
11244250646
-
Implication of the MAGI1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness
-
Kotelevets L, van HJ, Bruyneel E, Mareel M, van RF, Chastre E: Implication of the MAGI1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness. FASEB J 19:115-117,2005
-
(2005)
Faseb J
, vol.19
, pp. 115-117
-
-
Kotelevets, L.1
van, H.J.2
Bruyneel, E.3
Mareel, M.4
van, R.F.5
Chastre, E.6
-
22
-
-
0034976644
-
Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas
-
Kurose K, Zhou XP, Araki T, Cannistra SA, Maher ER, Eng C: Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas. Am J Pathol 158:2097-2106, 2001
-
(2001)
Am J Pathol
, vol.158
, pp. 2097-2106
-
-
Kurose, K.1
Zhou, X.P.2
Araki, T.3
Cannistra, S.A.4
Maher, E.R.5
Eng, C.6
-
23
-
-
0036583531
-
Tumor suppressor PTEN is mutated in canine osteosarcoma cell lines and tumors
-
Levine RA, Forest T, Smith C: Tumor suppressor PTEN is mutated in canine osteosarcoma cell lines and tumors. Vet Pathol 39:372-378, 2002
-
(2002)
Vet Pathol
, vol.39
, pp. 372-378
-
-
Levine, R.A.1
Forest, T.2
Smith, C.3
-
24
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:13375-13378, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
25
-
-
22344435644
-
PTEN expression in melanoma: Relationship with patient survival, Bcl-2 expression, and proliferation
-
Mikhail M, Velazquez E, Shapiro R, Berman R, Pavlick A, Sorhaindo L, Spira J, Mir C, Panageas KS, Polsky D, Osman I: PTEN expression in melanoma: relationship with patient survival, Bcl-2 expression, and proliferation. Clin Cancer Res 11:5153-5157, 2005
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5153-5157
-
-
Mikhail, M.1
Velazquez, E.2
Shapiro, R.3
Berman, R.4
Pavlick, A.5
Sorhaindo, L.6
Spira, J.7
Mir, C.8
Panageas, K.S.9
Polsky, D.10
Osman, I.11
-
27
-
-
0032857217
-
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
-
Perren A, Weng LP, Boag AH, Ziebold U, Thakore K, Dahia PL, Komminoth P, Lees JA, Mulligan LM, Mutter GL, Eng C: Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast. Am J Pathol 155:1253-1260, 1999
-
(1999)
Am J Pathol
, vol.155
, pp. 1253-1260
-
-
Perren, A.1
Weng, L.P.2
Boag, A.H.3
Ziebold, U.4
Thakore, K.5
Dahia, P.L.6
Komminoth, P.7
Lees, J.A.8
Mulligan, L.M.9
Mutter, G.L.10
Eng, C.11
-
29
-
-
45049085220
-
Expression and significance of PTEN in canine mammary gland tumours
-
Qiu C, Lin D, Wang J, Wang L: Expression and significance of PTEN in canine mammary gland tumours. Res Vet Sci 85:383-388, 2008
-
(2008)
Res Vet Sci
, vol.85
, pp. 383-388
-
-
Qiu, C.1
Lin, D.2
Wang, J.3
Wang, L.4
-
30
-
-
47749096343
-
Expression and significance of PTEN and VEGF in canine mammary gland tumours
-
Qiu CW, Lin DG, Wang JQ, Li CY, Deng GZ: Expression and significance of PTEN and VEGF in canine mammary gland tumours. Vet Res Commun 32:463-472, 2008
-
(2008)
Vet Res Commun
, vol.32
, pp. 463-472
-
-
Qiu, C.W.1
Lin, D.G.2
Wang, J.Q.3
Li, C.Y.4
Deng, G.Z.5
-
31
-
-
0030817576
-
PTEN gene mutations are seen in high-grade but not in low-grade gliomas
-
Rasheed BK, Stenzel TT, McLendon RE, Parsons R, Friedman AH, Friedman HS, Bigner DD, Bigner HH: PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 57:4187-4190,1997
-
(1997)
Cancer Res
, vol.57
, pp. 4187-4190
-
-
Rasheed, B.K.1
Stenzel, T.T.2
McLendon, R.E.3
Parsons, R.4
Friedman, A.H.5
Friedman, H.S.6
Bigner, D.D.7
Bigner, H.H.8
-
32
-
-
0030801275
-
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
-
Rhei E, Kang L, Bogomolniy F, Federici MG, Borgen PI, Boyd J: Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res 57:3657-3659,1997
-
(1997)
Cancer Res
, vol.57
, pp. 3657-3659
-
-
Rhei, E.1
Kang, L.2
Bogomolniy, F.3
Federici, M.G.4
Borgen, P.I.5
Boyd, J.6
-
33
-
-
0032212223
-
PTEN gene alterations in lymphoid neoplasms
-
Sakai A, Thieblemont C, Wellmann A, Jaffe ES, Raffeld M: PTEN gene alterations in lymphoid neoplasms. Blood 92:3410-3415, 1998
-
(1998)
Blood
, vol.92
, pp. 3410-3415
-
-
Sakai, A.1
Thieblemont, C.2
Wellmann, A.3
Jaffe, E.S.4
Raffeld, M.5
-
34
-
-
0037457314
-
Dysregulated PTEN-PKB and negative receptor status in human breast cancer
-
Shi W, Zhang X, Pintilie M, Ma N, Miller N, Banerjee D, Tsao MS, Mak T, Fyles A, Liu FF: Dysregulated PTEN-PKB and negative receptor status in human breast cancer. Int J Cancer 104:195-203, 2003
-
(2003)
Int J Cancer
, vol.104
, pp. 195-203
-
-
Shi, W.1
Zhang, X.2
Pintilie, M.3
Ma, N.4
Miller, N.5
Banerjee, D.6
Tsao, M.S.7
Mak, T.8
Fyles, A.9
Liu, F.F.10
-
35
-
-
38349030742
-
New insights into PTEN
-
Tamguney T, Stokoe D: New insights into PTEN. J Cell Sci 120:4071-4079, 2007
-
(2007)
J Cell Sci
, vol.120
, pp. 4071-4079
-
-
Tamguney, T.1
Stokoe, D.2
-
36
-
-
0033520712
-
PTEN gene and integrin signaling in cancer
-
Tamura M, Gu J, Tran H, Yamada KM: PTEN gene and integrin signaling in cancer. J Natl Cancer Inst 91:1820-1828, 1999
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1820-1828
-
-
Tamura, M.1
Gu, J.2
Tran, H.3
Yamada, K.M.4
-
37
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro H, Blazes MS, Wu R, Cho KR, Bose S, Wang SI, Li J, Parsons R, Ellenson LH: Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 57:3935-3940, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
Cho, K.R.4
Bose, S.5
Wang, S.I.6
Li, J.7
Parsons, R.8
Ellenson, L.H.9
-
38
-
-
23844530876
-
Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast
-
Tsutsui S, Inoue H, Yasuda K, Suzuki K, Higashi H, Era S, Mori M: Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast. Oncology 68:398-404, 2005
-
(2005)
Oncology
, vol.68
, pp. 398-404
-
-
Tsutsui, S.1
Inoue, H.2
Yasuda, K.3
Suzuki, K.4
Higashi, H.5
Era, S.6
Mori, M.7
-
39
-
-
0020621166
-
Prognostic factors in feline mammary carcinoma
-
Weijer K, Hart AA: Prognostic factors in feline mammary carcinoma. J Natl Cancer Inst 70:709-716,1983
-
(1983)
J Natl Cancer Inst
, vol.70
, pp. 709-716
-
-
Weijer, K.1
Hart, A.A.2
-
40
-
-
0032574718
-
Inactivation of the tumor suppressor PTEN/ MMAC1 in advanced human prostate cancer through loss of expression
-
Whang YE, Wu X, Suzuki H, Reiter RE, Tran C, Vessella RL, Said JW, Isaacs WB, Sawyers CL: Inactivation of the tumor suppressor PTEN/ MMAC1 in advanced human prostate cancer through loss of expression. Proc Natl Acad Sci USA 95:5246-5250, 1998
-
(1998)
Proc Natl Acad Sci Usa
, vol.95
, pp. 5246-5250
-
-
Whang, Y.E.1
Wu, X.2
Suzuki, H.3
Reiter, R.E.4
Tran, C.5
Vessella, R.L.6
Said, J.W.7
Isaacs, W.B.8
Sawyers, C.L.9
-
41
-
-
34248143461
-
Measurement of PTEN expression using tissue microarrays to determine a race-specific prognostic marker in breast cancer
-
Winter JL, Stackhouse BL, Russell GB, Kute TE: Measurement of PTEN expression using tissue microarrays to determine a race-specific prognostic marker in breast cancer. Arch Pathol Lab Med 131:767-772, 2007
-
(2007)
Arch Pathol Lab Med
, vol.131
, pp. 767-772
-
-
Winter, J.L.1
Stackhouse, B.L.2
Russell, G.B.3
Kute, T.E.4
|