Molecular plasticity of E-cadherin and sialyl lewis X expression, in two comparative models of mammary tumorigenesis

PLoS ONE

Volumn 4, Issue 8, 2009, Pages

  Pinho, Salomé S ^a   Reis, Celso A ^a,b   Gärtner, Fátima ^a   Alpaugh, Mary L ^c  

^a UNIVERSITY OF PORTO   (Portugal)

^b University of Porto   (Portugal)

^c CITY COLLEGE OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SIALYL LEWIS X ANTIGEN; UVOMORULIN; 5 ACETYLNEURAMINYL (2 3) GALACTOSYL (1 4) (FUCOPYRANOSYL (1 3)) N ACETYLGLUCOSAMINE; 5-ACETYLNEURAMINYL-(2-3)-GALACTOSYL-(1-4)-(FUCOPYRANOSYL-(1-3))-N-ACETYLGLUCOSAMINE; CADHERIN; OLIGOSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER GROWTH; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; METASTASIS POTENTIAL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PLASTICITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; STAINING; TUMOR MODEL; ANIMAL; CELL TRANSFORMATION; COMPARATIVE STUDY; DISEASE MODEL; DOG; EXPERIMENTAL NEOPLASM; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; CADHERINS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; DOGS; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; OLIGOSACCHARIDES;

EID: 68949159937     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006636     Document Type: Article

References (26)

1. Woodhouse EC, Chuaqui RF, Liotta LA (1997) General Mechanisms of Metastasis. Cancer 80: 1529-1537.
2. Liotta LA, Kohn EC (2001) The Microenvironment of the Tumour-host Interface. Nature 411: 375-379.
3. Joyce CT, Kalluri R (2007) Mechanisms of Metastasis: Epithelial-to-Mesenchymal Transition and Contribution of Tumor Microenvironment. J Cell Biochem 101: 816-829.
4. Liotta LA, Steeg PS, Stetler-Stevenson WG (1991) Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64: 327-336.
5. Eccles SA, Welch DR (2007) Metastasis: recent discoveries and novel treatment strategies. Lancet 369: 1742-1747.
6. Scheel C, Onder T, Karnoub A, Weinberg RA (2007) Adaptation versus Selection: The Origins of Metastatic Behavior. Cancer Res 67: 11476-11480.
7. Talmadge JE (2007) Clonal Selection of Metastasis within the Life History of a Tumor. Cancer Res 67: 11471-11475.
8. Wodarz A, Näthke I (2007) Cell polarity in development and cancer. Nat Cell Biol 9: 1016-1024.
9. Vincent-Salamon A, Thiery JP (2003) Epithelial-mesenchymal transition in breast cancer development. Breast Cancer Res 5: 101-106.
10. Couldrey C, Green JE (2000) Metastases: the glycan connection. Breast Cancer Res 2: 321-323.
11. Beavon IRG (2000) The E-cadherin-catenin complex in tumor metastasis: structure, function and regulation. Eur J Cancer 36: 1607-1620.
12. Kannagi R, Isawa M, Koike T, Miyazaki K, Kimura N (2004) Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesis. Cancer Sci 95: 377-384.
13. Wang PH (2005) Altered glycosylation in cancer: sialic acids and sialyltransferases. J Cancer Mol 1: 73-81.
14. Miyagi T, Wada T, Yamaguchi K, Hata K (2004) Sialidase and malignancy: a minireview. Glycoconj J 20: 189-198.
15. Varki A (2007) Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins. Nature 446: 1023-1029.
16. Paoloni M, Khana C (2008) Translation of new cancer treatments from pet dogs to humans. Nat Rev Cancer 8: 147-156.
17. Owen LN (1979) A comparative study of canine and human breast cancer. Invest Cell Pathol 2: 257-275.
18. Alpaugh ML, Tomlinson JS, Shao ZM, Barsky SH (1999) A Novel human xenograft model of Inflammatory Breast Cancer. Cancer Res 59: 5079-5084.
19. Hellmén E (1993) Canine mammary tumor cell lines established in vitro. J Reprod Fertil Suppl 47: 489-499.
20. Peña L, Perez-Alenza MD, Rodriguez-Bertos A, Nieto A (2003) Canine inflammatory mammary carcinoma: histopathology, immunohistochemistry and clinical implications of 21 cases. Breast Cancer Res Treat 78: 141-148.
21. Pérez-Alenza MD, Jiménez Á, Nieto AI, Peña L (2004) First description of feline inflammatory mammary carcinoma: clinicopathological and immunohistochemical characteristics of three cases. Breast Cancer Res 6: R300-R307.
22. Tomlinson JS, Alpaugh ML, Barsky SH (2001) An intact overexpressed E-cadherin/alpha, beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma. Cancer Res 61: 5231-5241.
23. Alpaugh ML, Tomlinson JS, Kasraeian S, Barsky SH (2002) Cooperative role of e-cadherin and sialyl-lewis x/a-deficient muc1 in the passive dissemination of tumor emboli in inflammatory breast carcinoma. Oncogene 21: 3631-3643.
24. x/a underexpression and e-cadherin overexpression in the lymphovascular embolus of inflammatory breast carcinoma. Am J Pathol 161: 619-628.
25. Pinho SS, Matos AJF, Lopes C, Marcos NT, Carvalheira J, et al. (2007) Sialyl Lewis x expression in canine malignant mammary tumors: correlation with clinicopathological features and E-cadherin expression. BMC Cancer 7: 124.
26. Ferrara AR (2008) Inflammatory breast cancer: challenges and development. Radiol Technol 80: 49-60.