BMP2 signals loss of epithelial character in epicardial cells but requires the Type III TGFβ receptor to promote invasion

Cellular Signalling

Volumn 24, Issue 5, 2012, Pages 1012-1022

  Hill, Cynthia R ^a   Sanchez, Nora S ^a   Love, Joseph D ^a   Arrieta, Julian A ^a   Hong, Charles C ^a,b,c   Brown, Christopher B ^a   Austin, Anita F ^a,d   Barnett, Joey V ^a  

^a Department of Pharmacology ^*  (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c Research Medicine Veterans Affairs TVHS   (United States)

^d MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

Bone morphogenic protein; Coronary vessels; Differentiation; Epicardium; Epithelial to mesenchymal transformation; Invasion; Transforming growth factor beta

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; CARBOXY TERMINAL TELOPEPTIDE; GROWTH FACTOR RECEPTOR; PROTEIN ALK2; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL INVASION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; EPICARDIUM; HEART MUSCLE CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; CORONARY VESSELS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; MICE; MICE, KNOCKOUT; MYOCYTES, SMOOTH MUSCLE; NEUROPEPTIDES; PERICARDIUM; PROTEOGLYCANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SMAD PROTEINS; TRANSFORMING GROWTH FACTORS;

MUS;

EID: 84857119750     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.12.022     Document Type: Article

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