Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3

Human Molecular Genetics

Volumn 18, Issue 5, 2009, Pages 942-955

  Tateno, Minako ^a   Kato, Shinsuke ^b   Sakurai, Takashi ^c   Nukina, Nobuyuki ^c   Takahashi, Ryosuke ^d   Araki, Toshiyuki ^a,e  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; COPPER ZINC SUPEROXIDE DISMUTASE; KINESIN; KINESIN ASSOCIATED PROTEIN 3; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINE UPTAKE; CONTROLLED STUDY; DISEASE COURSE; GENE MUTATION; GENE OVEREXPRESSION; MOUSE; NERVE FIBER TRANSPORT; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION;

ACETYLCHOLINE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AXONAL TRANSPORT; CELL LINE; CHOLINE O-ACETYLTRANSFERASE; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; MUTATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN TRANSPORT; SUPEROXIDE DISMUTASE;

MUS; MUS MUSCULUS;

EID: 60549104791     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn422     Document Type: Article

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