A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease

Neurobiology of Aging

Volumn 33, Issue 4, 2012, Pages 804-813

  Ma, Suk Ling ^a,b   Tang, Nelson Leung Sang ^b   Tam, Cindy Woon Chi ^b   Lui, Victor Wing Cheong ^b   Lam, Linda Chiu Wa ^b   Chiu, Helen Fung Kum ^b   Driver, Jane Ann ^a,c   Pastorino, Lucia ^a   Lu, Kun Ping ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN AP4; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; CHINESE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE; GENETIC TRANSFECTION; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NERVE CELL; ONSET AGE; PIN1 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ASIAN CONTINENTAL ANCESTRY GROUP; CELL LINE, TRANSFORMED; CHI-SQUARE DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; COMPUTATIONAL BIOLOGY; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; GENOTYPE; HONG KONG; HUMANS; MALE; MENTAL STATUS SCHEDULE; NEURONS; PEPTIDYLPROLYL ISOMERASE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; REGRESSION ANALYSIS; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84856970634     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.05.018     Document Type: Article

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