-
1
-
-
0036364359
-
-
Rogaeva E (2002) The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease. Neuromolecular Med 2: 1-10.
-
Rogaeva E (2002) The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease. Neuromolecular Med 2: 1-10.
-
-
-
-
2
-
-
65949104586
-
Genomewide association studies and human disease
-
Hardy J, Singleton A (2009) Genomewide association studies and human disease. N Engl J Med 360: 1759-1768.
-
(2009)
N Engl J Med
, vol.360
, pp. 1759-1768
-
-
Hardy, J.1
Singleton, A.2
-
3
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, et al. (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41: 1088-1093.
-
(2009)
Nat Genet
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
-
4
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, Campion D, Sleegers K, et al. (2009) Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41: 1094-1099.
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
-
5
-
-
0025301469
-
Apolipoprotein J: Structure and tissue distribution
-
de Silva HV, Harmony JA, Stuart WD, Gil CM, Robbins J (1990) Apolipoprotein J: structure and tissue distribution. Biochemistry 29: 5380-5389.
-
(1990)
Biochemistry
, vol.29
, pp. 5380-5389
-
-
de Silva, H.V.1
Harmony, J.A.2
Stuart, W.D.3
Gil, C.M.4
Robbins, J.5
-
6
-
-
0027248505
-
Localization of sulfated glycoprotein-2/clusterin mRNA in the rat brain by in situ hybridization
-
Danik M, Chabot JG, Hassan-Gonzalez D, Suh M, Quirion R (1993) Localization of sulfated glycoprotein-2/clusterin mRNA in the rat brain by in situ hybridization. J Comp Neurol 334: 209-227.
-
(1993)
J Comp Neurol
, vol.334
, pp. 209-227
-
-
Danik, M.1
Chabot, J.G.2
Hassan-Gonzalez, D.3
Suh, M.4
Quirion, R.5
-
7
-
-
0027516472
-
Genomic organization and expression of the rat TRPM-2 (clusterin) gene, a gene implicated in apoptosis
-
Wong P, Pineault J, Lakins J, Taillefer D, Leger J, et al. (1993) Genomic organization and expression of the rat TRPM-2 (clusterin) gene, a gene implicated in apoptosis. J Biol Chem 268: 5021-5031.
-
(1993)
J Biol Chem
, vol.268
, pp. 5021-5031
-
-
Wong, P.1
Pineault, J.2
Lakins, J.3
Taillefer, D.4
Leger, J.5
-
8
-
-
0026600180
-
Clusterin: The intriguing guises of a widely expressed glycoprotein
-
Jenne DE, Tschopp J (1992) Clusterin: the intriguing guises of a widely expressed glycoprotein. Trends Biochem Sci 17: 154-159.
-
(1992)
Trends Biochem Sci
, vol.17
, pp. 154-159
-
-
Jenne, D.E.1
Tschopp, J.2
-
10
-
-
0027970527
-
Purification and characterization of brain clusterin
-
Oda T, Pasinetti GM, Osterburg HH, Anderson C, Johnson SA, et al. (1994) Purification and characterization of brain clusterin. Biochem Biophys Res Commun 204: 1131-1136.
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 1131-1136
-
-
Oda, T.1
Pasinetti, G.M.2
Osterburg, H.H.3
Anderson, C.4
Johnson, S.A.5
-
11
-
-
0025642562
-
Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat
-
May PC, Lampert-Etchells M, Johnson SA, Poirier J, Masters JN, et al. (1990) Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat. Neuron 5: 831-839.
-
(1990)
Neuron
, vol.5
, pp. 831-839
-
-
May, P.C.1
Lampert-Etchells, M.2
Johnson, S.A.3
Poirier, J.4
Masters, J.N.5
-
12
-
-
0026537880
-
Distribution of clusterin in Alzheimer brain tissue
-
McGeer PL, Kawamata T, Walker DG (1992) Distribution of clusterin in Alzheimer brain tissue. Brain Res 579: 337-341.
-
(1992)
Brain Res
, vol.579
, pp. 337-341
-
-
McGeer, P.L.1
Kawamata, T.2
Walker, D.G.3
-
13
-
-
0028390708
-
Analysis of the 80 kDa antigen in senile plaque amyloid]
-
Takamaru Y (1994) [Analysis of the 80 kDa antigen in senile plaque amyloid]. Hokkaido Igaku Zasshi 69: 191-201.
-
(1994)
Hokkaido Igaku Zasshi
, vol.69
, pp. 191-201
-
-
Takamaru, Y.1
-
14
-
-
0028541162
-
Pathological proteins in senile plaques
-
McGeer PL, Klegeris A, Walker DG, Yasuhara O, McGeer EG (1994) Pathological proteins in senile plaques. Tohoku J Exp Med 174: 269-277.
-
(1994)
Tohoku J Exp Med
, vol.174
, pp. 269-277
-
-
McGeer, P.L.1
Klegeris, A.2
Walker, D.G.3
Yasuhara, O.4
McGeer, E.G.5
-
15
-
-
0029002233
-
-
Kida E, Choi-Miura NH, Wisniewski KE (1995) Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain. Brain Res 685: 211-216.
-
Kida E, Choi-Miura NH, Wisniewski KE (1995) Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain. Brain Res 685: 211-216.
-
-
-
-
16
-
-
0027186334
-
The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex
-
Ghiso J, Matsubara E, Koudinov A, Choi-Miura NH, Tomita M, et al. (1993) The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex. Biochem J 293 (Pt 1): 27-30.
-
(1993)
Biochem J
, vol.293
, Issue.PART 1
, pp. 27-30
-
-
Ghiso, J.1
Matsubara, E.2
Koudinov, A.3
Choi-Miura, N.H.4
Tomita, M.5
-
17
-
-
0029063033
-
Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid
-
Golabek A, Marques MA, Lalowski M, Wisniewski T (1995) Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid. Neurosci Lett 191: 79-82.
-
(1995)
Neurosci Lett
, vol.191
, pp. 79-82
-
-
Golabek, A.1
Marques, M.A.2
Lalowski, M.3
Wisniewski, T.4
-
18
-
-
0030604067
-
-
Zlokovic BV (1996) Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier. Life Sci 59: 1483-1497.
-
Zlokovic BV (1996) Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier. Life Sci 59: 1483-1497.
-
-
-
-
19
-
-
0029119753
-
Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein
-
Bertrand P, Poirier J, Oda T, Finch CE, Pasinetti GM (1995) Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. Brain Res Mol Brain Res 33: 174-178.
-
(1995)
J (clusterin) in Alzheimer disease. Brain Res Mol Brain Res
, vol.33
, pp. 174-178
-
-
Bertrand, P.1
Poirier, J.2
Oda, T.3
Finch, C.E.4
Pasinetti, G.M.5
-
20
-
-
64149105182
-
Genetic control of human brain transcript expression in Alzheimer disease
-
Webster JA, Gibbs JR, Clarke J, Ray M, Zhang W, et al. (2009) Genetic control of human brain transcript expression in Alzheimer disease. Am J Hum Genet 84: 445-458.
-
(2009)
Am J Hum Genet
, vol.84
, pp. 445-458
-
-
Webster, J.A.1
Gibbs, J.R.2
Clarke, J.3
Ray, M.4
Zhang, W.5
-
21
-
-
21044454051
-
Insertion/deletion polymorphism in clusterin gene influences serum lipid levels and carotid intima-media thickness in hypertensive Japanese females
-
Miwa Y, Takiuchi S, Kamide K, Yoshii M, Horio T, et al. (2005) Insertion/deletion polymorphism in clusterin gene influences serum lipid levels and carotid intima-media thickness in hypertensive Japanese females. Biochem Biophys Res Commun 331: 1587-1593.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 1587-1593
-
-
Miwa, Y.1
Takiuchi, S.2
Kamide, K.3
Yoshii, M.4
Horio, T.5
-
22
-
-
85196587756
-
-
Nestlerode CS, Bunker CH, Sanghera DK, Aston CE, Ukoli FA, et al. (1999) Apolipoprotein J polymorphisms and serum HDL cholesterol levels in African blacks. Hum Biol 71: 197-218.
-
Nestlerode CS, Bunker CH, Sanghera DK, Aston CE, Ukoli FA, et al. (1999) Apolipoprotein J polymorphisms and serum HDL cholesterol levels in African blacks. Hum Biol 71: 197-218.
-
-
-
-
23
-
-
10144219962
-
Polymorphisms in the human apolipoprotein-J/clusterin gene: Ethnic variation and distribution in Alzheimer's disease
-
Tycko B, Feng L, Nguyen L, Francis A, Hays A, et al. (1996) Polymorphisms in the human apolipoprotein-J/clusterin gene: ethnic variation and distribution in Alzheimer's disease. Hum Genet 98: 430-436.
-
(1996)
Hum Genet
, vol.98
, pp. 430-436
-
-
Tycko, B.1
Feng, L.2
Nguyen, L.3
Francis, A.4
Hays, A.5
-
24
-
-
70350238360
-
Unraveling a multifactorial late-onset disease: From genetic susceptibility to disease mechanisms for age-related macular degeneration
-
Swaroop A, Chew EY, Rickman CB, Abecasis GR (2009) Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet 10: 19-43.
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 19-43
-
-
Swaroop, A.1
Chew, E.Y.2
Rickman, C.B.3
Abecasis, G.R.4
-
25
-
-
34347383973
-
Familial genes in sporadic disease: Common variants of alpha-synuclein gene associate with Parkinson's disease
-
Ross OA, Gosal D, Stone JT, Lincoln SJ, Heckman MG, et al. (2007) Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease. Mech Ageing Dev 128: 378-382.
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 378-382
-
-
Ross, O.A.1
Gosal, D.2
Stone, J.T.3
Lincoln, S.J.4
Heckman, M.G.5
-
26
-
-
68649117544
-
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP
-
in press
-
Guerreiro RJ, Baquero M, Blesa R, Boada M, Bras JM, et al. (2008) Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP. Neurobiol Aging: in press.
-
(2008)
Neurobiol Aging
-
-
Guerreiro, R.J.1
Baquero, M.2
Blesa, R.3
Boada, M.4
Bras, J.M.5
-
27
-
-
0035869223
-
Prediction of deleterious human alleles
-
Sunyaev S, Ramensky V, Koch I, Lathe W, 3rd, Kondrashov AS, et al. (2001) Prediction of deleterious human alleles. Hum Mol Genet 10: 591-597.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 591-597
-
-
Sunyaev, S.1
Ramensky, V.2
Koch, I.3
Lathe 3rd, W.4
Kondrashov, A.S.5
-
28
-
-
0036713510
-
Human non-synonymous SNPs: Server and survey
-
Ramensky V, Bork P, Sunyaev S (2002) Human non-synonymous SNPs: server and survey. Nucleic Acids Res 30: 3894-3900.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 3894-3900
-
-
Ramensky, V.1
Bork, P.2
Sunyaev, S.3
-
29
-
-
0034191958
-
Towards a structural basis of human non-synonymous single nucleotide polymorphisms
-
Sunyaev S, Ramensky V, Bork P (2000) Towards a structural basis of human non-synonymous single nucleotide polymorphisms. Trends Genet 16: 198-200.
-
(2000)
Trends Genet
, vol.16
, pp. 198-200
-
-
Sunyaev, S.1
Ramensky, V.2
Bork, P.3
-
30
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
-
31
-
-
36549053104
-
A survey of genetic human cortical gene expression
-
Myers AJ, Gibbs JR, Webster JA, Rohrer K, Zhao A, et al. (2007) A survey of genetic human cortical gene expression. Nat Genet 39: 1494-1499.
-
(2007)
Nat Genet
, vol.39
, pp. 1494-1499
-
-
Myers, A.J.1
Gibbs, J.R.2
Webster, J.A.3
Rohrer, K.4
Zhao, A.5
-
32
-
-
0034118493
-
Inference of population structure using multilocus genotype data
-
Pritchard JK, Stephens M, Donnelly P (2000) Inference of population structure using multilocus genotype data. Genetics 155: 945-959.
-
(2000)
Genetics
, vol.155
, pp. 945-959
-
-
Pritchard, J.K.1
Stephens, M.2
Donnelly, P.3
-
33
-
-
0041817568
-
Inference of population structure using multilocus genotype data: Linked loci and correlated allele frequencies
-
Falush D, Stephens M, Pritchard JK (2003) Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 164: 1567-1587.
-
(2003)
Genetics
, vol.164
, pp. 1567-1587
-
-
Falush, D.1
Stephens, M.2
Pritchard, J.K.3
-
34
-
-
0037200201
-
A new nonlinear normalization method for reducing variability in DNA microarray experiments
-
research0048
-
Workman C, Jensen LJ, Jarmer H, Berka R, Gautier L, et al. (2002) A new nonlinear normalization method for reducing variability in DNA microarray experiments. Genome Biol 3: research0048.
-
(2002)
Genome Biol
, vol.3
-
-
Workman, C.1
Jensen, L.J.2
Jarmer, H.3
Berka, R.4
Gautier, L.5
-
35
-
-
0035752668
-
Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data
-
Schadt EE, Li C, Ellis B, Wong WH (2001) Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data. J Cell Biochem Suppl Suppl 37: 120-125.
-
(2001)
J Cell Biochem Suppl
, Issue.SUPPL. 37
, pp. 120-125
-
-
Schadt, E.E.1
Li, C.2
Ellis, B.3
Wong, W.H.4
-
36
-
-
0035875553
-
Issues in cDNA microarray analysis: Quality filtering, channel normalization, models of variations and assessment of gene effects
-
Tseng GC, Oh MK, Rohlin L, Liao JC, Wong WH (2001) Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects. Nucleic Acids Res 29: 2549-2557.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2549-2557
-
-
Tseng, G.C.1
Oh, M.K.2
Rohlin, L.3
Liao, J.C.4
Wong, W.H.5
|