Quantifying millisecond exchange dynamics in proteins by CPMG relaxation dispersion NMR using side-chain 1H probes

Journal of the American Chemical Society

Volumn 134, Issue 6, 2012, Pages 3178-3189

  Hansen, Alexandar L ^a   Lundström, Patrik ^b   Velyvis, Algirdas ^a   Kay, Lewis E ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b LINKÖPING UNIVERSITY   (Sweden)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL EXCHANGE; COLICIN E7; DISPERSION PROFILE; EXCHANGE DYNAMICS; HOMONUCLEAR SCALAR COUPLINGS; IMMUNITY PROTEINS; LABELING STRATEGY; PROTONATED MOLECULES; RELAXATION DISPERSION; SIDE-CHAINS; STRUCTURAL STUDIES; TIME-SCALES; TRANSVERSE RELAXATION RATE;

AMINO ACIDS; CHEMICAL SHIFT; EXPERIMENTS; GLUCOSE; PROTEINS;

DISPERSIONS;

AMINO ACID; CARBON 13; COLICIN; COLICIN E7; DEUTERIUM OXIDE; GLUCOSE; PROTEIN; PROTON; UNCLASSIFIED DRUG;

ANISOTROPY; ARTICLE; BIOSYNTHESIS; MOLECULAR DYNAMICS; MOLECULE; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS;

AMINO ACIDS; CARRIER PROTEINS; CHEMISTRY; COLICINS; DEUTERIUM OXIDE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLUCOSE; KINETICS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTEINS; PROTONS; SOLVENTS; TIME FACTORS;

EID: 84856912378     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja210711v     Document Type: Article

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