Probing microsecond time scale dynamics in proteins by methyl 1H Carr-Purcell-Meiboom-Gill relaxation dispersion NMR measurements. Application to activation of the signaling protein NtrCr

Journal of the American Chemical Society

Volumn 132, Issue 47, 2010, Pages 17004-17014

  Otten, Renee ^a   Villali, Janice ^b   Kern, Dorothee ^b   Mulder, Frans A A ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE STATE; COMPREHENSIVE STUDIES; CONFORMATIONAL EQUILIBRIUM; CONFORMATIONAL SWITCHING; COVALENT MODIFICATIONS; D-GLUCOSE; DEUTERATIONS; DYNAMIC EQUILIBRIA; FREE COMPONENT; FUNCTIONAL MOTIONS; LEUCINE RESIDUES; LOW POWER; METHIONINE RESIDUES; METHYL GROUP; METHYL GROUP DYNAMICS; NMR MEASUREMENTS; NMR SPECTROSCOPY; PHOSPHORYLATION SITES; PROTEIN SAMPLES; PULSE TRAIN; QUANTITATIVE STUDY; RELAXATION DISPERSION; RELAXATION PROPERTY; SCALAR COUPLING; SHORT PULSE; SIDE CHAINS; SIGNALING PROTEINS; SIGNALING STATE; SOLUTION NMR; STATE TRANSITIONS; STRUCTURAL REARRANGEMENT; TIME RANGE; TIME-SCALES; TRANSCRIPTIONAL ACTIVATORS; TRANSVERSE RELAXATION RATE;

AMINO ACIDS; CHEMICAL ACTIVATION; DEUTERIUM; DYNAMICS; EXPERIMENTS; FUNCTIONAL GROUPS; GLUCOSE; LOCOMOTIVES; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORYLATION; PROBES; PROTEINS; RAILROAD CARS; RATE CONSTANTS; SIGNALING; TIME MEASUREMENT;

DISPERSIONS;

CARBON 13; LEUCINE; METHYL GROUP; NITROGEN 15;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; COVALENT BOND; DISPERSION; METHYL 1H CARR PURCELL MEIBOOM GILL RELAXATION DISPERSION SPECTROSCOPY; MOLECULAR DYNAMICS; MOLECULAR PROBE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORYLATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; TRANSCRIPTION INITIATION;

BACTERIAL PROTEINS; DEUTERIUM OXIDE; GLUCOSE; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY; PROTONS; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 78649509231     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja107410x     Document Type: Article

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