Using amide 1H and 15N transverse relaxation to detect millisecond time-scale motions in perdeuterated proteins: Application to HIV-1 protease

Journal of the American Chemical Society

Volumn 120, Issue 40, 1998, Pages 10534-10542

  Ishima, Rieko ^a   Wingfield, Paul T ^b   Stahl, Stephen J ^b   Kaufman, Joshua D ^b   Torchia, Dennis A ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ARTICLE; ENZYME CHEMISTRY; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEAR OVERHAUSER EFFECT; TIME;

EID: 0032517325     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja981546c     Document Type: Article

References (11)

1. Mueller, L. J. Am. Chem. Soc. 1979, 101, 4481-4484.
2. Morris, G. A.; Freeman, R. J. Am. Chem. Soc. 1979, 101, 760-762.
3. Bodenhausen, G.; Ruben, D. J. Chem. Phys. Lett. 1980, 69, 185-189.
4. Nirmala, N. R.; Wagner, G. J. Am. Chem. Soc. 1988, 110, 7557-7558.
5. Kay, L. E.; Torchia, D. A.; Bax, A. Biochemistry 1989, 28, 8972-8979.
6. Akke, M.; Liu, J.; Cavanash, J.; Erickson, H.; Palmer, A. G. Nat. Struct. Biol. 1998, 5, 55-59.
7. Mandel, A. M.; Akke, M.; Palmer, A. G. R. Biochemistry 1996, 35, 16009-16023.
8. Allerhand, A.; Gutowsky, H. S. J. Chem. Phys. 1964, 41, 2115-2126.
9. Allerhand, A.; Gutowsky, H. S. J. Chem. Phys. 1965, 42, 1587-1598.
10. Williamson, M. P. Biopolymers 1990, 29, 1423-1431.
11. Wang, Y. X.; Freedberg, D. I.; Grzesiek, S.; Torchia, D. A.; Wingfield, P. T.; Kaufman, J. D.; Stahl, S. J.; Chang, C. H.; Hodge, C. N. Biochemistry 1996, 35, 12694-12704.