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Volumn 2, Issue NOV, 2011, Pages

GPR35 as a novel therapeutic target

Author keywords

Cardiovascular disease; Diabetes; G proteins; GPR35

Indexed keywords


EID: 84856841342     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2011.00068     Document Type: Review
Times cited : (66)

References (68)
  • 1
    • 0026063223 scopus 로고
    • Altered expression of inhibitory guanine nucleotide regulatory proteins (Gi alpha) in spontaneously hypertensive rats
    • Anand-Srivastava, M. B., Picard, S., and Thibault, C. (1991). Altered expression of inhibitory guanine nucleotide regulatory proteins (Gi alpha) in spontaneously hypertensive rats. Am.J.Hypertens.4, 840-843.
    • (1991) Am.J.Hypertens , vol.4 , pp. 840-843
    • Anand-Srivastava, M.B.1    Picard, S.2    Thibault, C.3
  • 2
    • 49949098676 scopus 로고    scopus 로고
    • Two pathways for lysophos-phatidic acid production
    • Aoki, J., Inoue, A., and Okudaira, S. (2008). Two pathways for lysophos-phatidic acid production. Biochem. Biophys. Acta 1781, 513-518.
    • (2008) Biochem. Biophys. Acta , vol.1781 , pp. 513-518
    • Aoki, J.1    Inoue, A.2    Okudaira, S.3
  • 6
    • 62549117414 scopus 로고    scopus 로고
    • Recent advances in the treatment of amyotrophic lateral sclerosis Emphasis on kynurenine pathway inhibitors
    • Chen, Y., Meininger, V., and Guillemin, G. J. (2009). Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors. Cent. Nerv. Syst. Agents Med. Chem. 9, 32-39.
    • (2009) Cent. Nerv. Syst. Agents Med. Chem. , vol.9 , pp. 32-39
    • Chen, Y.1    Meininger, V.2    Guillemin, G.J.3
  • 7
    • 0036325594 scopus 로고    scopus 로고
    • Rac regulates endothelial morphogenesis and capillary assembly
    • Connolly, J. O., Simpson, N., Hewlett, L., and Hall, A. (2002). Rac regu-lates endothelial morphogenesis and capillary assembly. Mol. Biol. Cell 13, 2474-2485.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2474-2485
    • Connolly, J.O.1    Simpson, N.2    Hewlett, L.3    Hall, A.4
  • 8
    • 79954585445 scopus 로고    scopus 로고
    • G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast
    • Cosi,C.,Mannaioni,G.,Cozzi,A.,Carla, V., Sili, M., Cavone, L., Maratea, D., and Moroni, F. (2010). G-protein coupled receptor 35 (GPR35) acti-vation and inflammatory pain: Stud-ies on the antinociceptive effects of kynurenic acid and zaprinast. Neu-ropharmacology 60, 1227-1231.
    • (2010) Neu-ropharmacology , vol.60 , pp. 1227-1231
    • Cosi, C.1    Mannaioni, G.2    Cozzi, A.3    Carla, V.4    Sili, M.5    Cavone, L.6    Maratea, D.7    Moroni, F.8
  • 9
    • 79958142575 scopus 로고    scopus 로고
    • Tyrphostin analogs are GPR35 agonists
    • Deng, H., Hu, H., and Fang, Y. (2011). Tyrphostin analogs are GPR35 ago-nists. FEBS Lett. 585, 1957-1962.
    • (2011) FEBS Lett , vol.585 , pp. 1957-1962
    • Deng, H.1    Hu, H.2    Fang, Y.3
  • 11
    • 67650410457 scopus 로고    scopus 로고
    • Yeast assays for G protein-coupled receptors
    • Dowell, S. J., and Brown, A. J. (2009). Yeast assays for G protein-coupled receptors. Methods Mol. Biol. 552, 213-229.
    • (2009) Methods Mol. Biol. , vol.552 , pp. 213-229
    • Dowell, S.J.1    Brown, A.J.2
  • 13
    • 0038024615 scopus 로고    scopus 로고
    • The G-protein-coupled receptors in the human genome form five main families. Phyloge-netic analysis,paralogon groups,and fingerprints
    • Fredriksson, R., Lagerstrom, M. C., Lundin, L. G., and Schioth, H. B. (2003). The G-protein-coupled receptors in the human genome form five main families. Phyloge-netic analysis,paralogon groups,and fingerprints. Mol. Pharmacol. 63, 1256-1272.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 1256-1272
    • Fredriksson, R.1    Lagerstrom, M.C.2    Lundin, L.G.3    Schioth, H.B.4
  • 15
    • 37349129072 scopus 로고    scopus 로고
    • Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons
    • Guo, J., Williams, D. J., Puhl, H. L. III., and Ikeda, S. R. (2008). Inhibition of N-type calcium channels by activa-tion of GPR35, an orphan receptor, heterologously expressed in rat sym-pathetic neurons. J. Pharmacol. Exp. Ther. 324, 342-351.
    • (2008) J. Pharmacol. Exp. Ther. , vol.324 , pp. 342-351
    • Guo, J.1    Williams, D.J.2    Puhl III, H.L.3    Ikeda, S.R.4
  • 16
    • 24144488192 scopus 로고    scopus 로고
    • High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay
    • Hamdan, F. F., Audet, M., Garneau, P., Pelletier, J., and Bouvier, M. (2005). High-throughput screening of G protein-coupled receptor antago-nists using a bioluminescence reso-nance energy transfer 1-based beta-arrestin2 recruitment assay. J. Bio-mol. Screen. 10, 463-475.
    • (2005) J. Bio-mol. Screen. , vol.10 , pp. 463-475
    • Hamdan, F.F.1    Audet, M.2    Garneau, P.3    Pelletier, J.4    Bouvier, M.5
  • 18
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increaes non-alpha7 nicotinic receptor expression: phys-iopathological implications
    • Hilmas, C., Pereira, E. F., Alkondon, M., Rassoulpour, A., Schwarcz, R., and Albuquerque, E. X. (2001). The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increaes non-alpha7 nicotinic receptor expression: phys-iopathological implications. J. Neu-rosci. 21, 7463-7473.
    • (2001) J. Neu-rosci. , vol.21 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 21
    • 78649881120 scopus 로고    scopus 로고
    • Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2
    • Jenkins, L., Alvarez-Curto, E., Camp-bell, K., de Munnik, S., Canals, M., Schlyer, S., and Milligan, G. (2011). Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2. Br. J. Pharmacol. 162, 733-748.
    • (2011) Br. J. Pharmacol. , vol.162 , pp. 733-748
    • Jenkins, L.1    Alvarez-Curto, E.2    Camp-Bell, K.3    de Munnik, S.4    Canals, M.5    Schlyer, S.6    Milligan, G.7
  • 22
    • 78649859393 scopus 로고    scopus 로고
    • Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of beta-arrestin-2 and activate Gal-pha13
    • Jenkins, L., Brea, J., Smith, N. J., Hud-son, B. D., Reilly, G., Bryant, N. J., Castro, M., Loza, M. I., and Milligan, G. (2010). Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of beta-arrestin-2 and activate Gal-pha13. Biochem. J. 432, 451-459.
    • (2010) Biochem. J. , vol.432 , pp. 451-459
    • Jenkins, L.1    Brea, J.2    Smith, N.J.3    Hud-Son, B.D.4    Reilly, G.5    Bryant, N.J.6    Castro, M.7    Loza, M.I.8    Milligan, G.9
  • 24
    • 27144434813 scopus 로고    scopus 로고
    • Promiscuous Gα proteins in basic research and drug discovery
    • Kostenis, E., Waelbroeck, M., and Mil-ligan, G. (2005). Promiscuous Gα proteins in basic research and drug discovery. Trends Pharmacol. Sci. 26, 595-602.
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 595-602
    • Kostenis, E.1    Waelbroeck, M.2    Mil-Ligan, G.3
  • 28
    • 0037047665 scopus 로고    scopus 로고
    • Inactivation of enhanced expression of G(i) proteins by pertussis toxin attenuates the develop-ment of high blood pressure in spon-taneously hypertensive rats
    • Li, Y., and Anand-Srivastava, M. B. (2002). Inactivation of enhanced expression of G(i) proteins by per-tussis toxin attenuates the develop-ment of high blood pressure in spon-taneously hypertensive rats. Circ. Res. 91, 247-254.
    • (2002) Circ. Res. , vol.91 , pp. 247-254
    • Li, Y.1    Anand-Srivastava, M.B.2
  • 29
    • 0038702295 scopus 로고    scopus 로고
    • 'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors
    • Luttrell, L. M. (2003). 'Location, loca-tion, location': activation and tar-geting of MAP kinases by G protein-coupled receptors. J. Mol. Endocrinol. 30, 117-126.
    • (2003) J. Mol. Endocrinol. , vol.30 , pp. 117-126
    • Luttrell, L.M.1
  • 32
    • 0037305047 scopus 로고    scopus 로고
    • Principles: extending the utility of [35S]GTP gamma S binding assays
    • Milligan, G. (2003). Principles: extend-ing the utility of [35S]GTP gamma S binding assays. Trends Pharmacol. Sci. 24, 87-90.
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 87-90
    • Milligan, G.1
  • 33
    • 79955738004 scopus 로고    scopus 로고
    • Orthologue selectivity and ligand bias: translating the pharmacology of GPR35
    • Milligan, G. (2011). Orthologue selec-tivity and ligand bias: translating the pharmacology of GPR35. Trends Pharmacol. Sci. 32, 317-325.
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 317-325
    • Milligan, G.1
  • 34
    • 30444435782 scopus 로고    scopus 로고
    • Hetero-trimeric G proteins: a short history
    • Milligan, G., and Kostenis, E. (2006). Hetero-trimeric G proteins: a short history. Br. J. Pharmacol. 147, S46- S55.
    • (2006) Br. J. Pharmacol. , vol.147
    • Milligan, G.1    Kostenis, E.2
  • 35
    • 0042887042 scopus 로고    scopus 로고
    • The emerging role of lysophosphatidic acid in cancer
    • Mills, G. B., and Moolenaar, W. H. (2003). The emerging role of lysophosphatidic acid in cancer. Nat. Rev. Cancer 3, 582-591.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 582-591
    • Mills, G.B.1    Moolenaar, W.H.2
  • 39
    • 77957237878 scopus 로고    scopus 로고
    • Mind your salts: when the inactive constituent isn't
    • Neubig, R. R. (2010). Mind your salts: when the inactive constituent isn't. Mol. Pharmacol. 78, 558-559.
    • (2010) Mol. Pharmacol. , vol.78 , pp. 558-559
    • Neubig, R.R.1
  • 42
    • 0031015426 scopus 로고    scopus 로고
    • Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
    • Offermanns, S., Mancino, V., Revel, J. P., and Simon, M. I. (1997). Vas-cular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science 275, 533-536.
    • (1997) Science , vol.275 , pp. 533-536
    • Offermanns, S.1    Mancino, V.2    Revel, J.P.3    Simon, M.I.4
  • 43
    • 36248949170 scopus 로고    scopus 로고
    • GPR35 is a functional receptor in rat dorsal root ganglion neurons
    • Ohshiro, H., Tonai-Kachi, H., and Ichikawa, K. (2008). GPR35 is a functional receptor in rat dorsal root ganglion neurons. Biochem. Biophys. Res. Commun. 365, 344-348.
    • (2008) Biochem. Biophys. Res. Commun. , vol.365 , pp. 344-348
    • Ohshiro, H.1    Tonai-Kachi, H.2    Ichikawa, K.3
  • 45
    • 1642445349 scopus 로고    scopus 로고
    • Cloning of a G-protein-coupled receptor that shows an activity to transform NIH3T3 cells and is expressed in gastric cancer cells
    • Okumura, S., Baba, H., Kumada, T., Nanmoku, K., Nakajima, H., Nakane, Y., Hioki, K., and Ikenaka, K. (2004). Cloning of a G-protein-coupled receptor that shows an activity to transform NIH3T3 cells and is expressed in gastric cancer cells. Cancer Sci. 95, 131-135.
    • (2004) Cancer Sci , vol.95 , pp. 131-135
    • Okumura, S.1    Baba, H.2    Kumada, T.3    Nanmoku, K.4    Nakajima, H.5    Nakane, Y.6    Hioki, K.7    Ikenaka, K.8
  • 47
    • 0036184490 scopus 로고    scopus 로고
    • Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure
    • Pawlak, D., Tankiewicz, A., Mysliwiec, P., and Buczko, W. (2002). Trypto-phan metabolism via the kynurenine pathway in experimental chronic renal failure. Nephron 90, 328-335.
    • (2002) Nephron , vol.90 , pp. 328-335
    • Pawlak, D.1    Tankiewicz, A.2    Mysliwiec, P.3    Buczko, W.4
  • 48
    • 33646780229 scopus 로고    scopus 로고
    • Kynurenic acid has a dual action on AMPA receptor responses
    • Prescott, C., Weeks, A. M., Staley, K. J., and Partin, K. M. (2006). Kynurenic acid has a dual action on AMPA receptor responses. Neurosci. Lett. 402, 108-112.
    • (2006) Neurosci. Lett. , vol.402 , pp. 108-112
    • Prescott, C.1    Weeks, A.M.2    Staley, K.J.3    Partin, K.M.4
  • 49
    • 0344417883 scopus 로고    scopus 로고
    • Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve end-ings in mice
    • Renback, K., Inoue, M., and Ueda, H. (1999). Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve end-ings in mice. Neurosci. Lett. 270, 59-61.
    • (1999) Neurosci. Lett. , vol.270 , pp. 59-61
    • Renback, K.1    Inoue, M.2    Ueda, H.3
  • 51
    • 0035929135 scopus 로고    scopus 로고
    • The effects of endothelin-1 on ischaemia-induced ventricular arrhythmias in rat isolated hearts
    • Sharif, I., Crockett, T. R., Kane, K. A., and Wainwright, C. L. (2001). The effects of endothelin-1 on ischaemia-induced ventricular arrhythmias in rat isolated hearts. Eur. J. Pharmacol. 427, 235-242.
    • (2001) Eur. J. Pharmacol. , vol.427 , pp. 235-242
    • Sharif, I.1    Crockett, T.R.2    Kane, K.A.3    Wainwright, C.L.4
  • 52
    • 9444226945 scopus 로고    scopus 로고
    • Molecular delineation of deletions on 2q37 3 in three cases with an Albright hereditary osteodystrophy-like phenotype
    • Shrimpton, A. E., Braddock, B. R., Thomson, L. L., Stein, C. K., and Hoo, J. J. (2004). Molecular delin-eation of deletions on 2q37.3 in three cases with an Albright heredi-tary osteodystrophy-like phenotype. Clin. Genet. 66, 537-544.
    • (2004) Clin. Genet. , vol.66 , pp. 537-544
    • Shrimpton, A.E.1    Braddock, B.R.2    Thomson, L.L.3    Stein, C.K.4    Hoo, J.J.5
  • 54
    • 77951601769 scopus 로고    scopus 로고
    • Transcriptional signature of human macrophages exposed to the environmental contaminant benzo(a)pyrene
    • Sparfel, L., Pinel-Marie, M. L., Boize, M., Koscielny, S., Desmots, S., Pery, A., and Fardel, O. (2010). Transcriptional signature of human macrophages exposed to the environmental contaminant benzo(a)pyrene. Toxicol. Sci. 114, 247-259.
    • (2010) Toxicol. Sci. , vol.114 , pp. 247-259
    • Sparfel, L.1    Pinel-Marie, M.L.2    Boize, M.3    Koscielny, S.4    Desmots, S.5    Pery, A.6    Fardel, O.7
  • 55
    • 0035066870 scopus 로고    scopus 로고
    • Kynurenic acid antagonists and kynurenine pathway inhibitors
    • Stone, T. W. (2001). Kynurenic acid antagonists and kynurenine path-way inhibitors. Expert Opin. Investig. Drugs 10, 633-645.
    • (2001) Expert Opin. Investig. Drugs , vol.10 , pp. 633-645
    • Stone, T.W.1
  • 56
    • 0032834470 scopus 로고    scopus 로고
    • Occurrence of lysophosphatidic acid and its alkyl etherlinked analog in rat brain and comparison of their biological activities toward cultured neural cells
    • Sugiura, T., Nakane, S., Kishimoto, S., Waku, K., Yoshioka, Y., Tokumura, A., and Hanahan, D. J. (1999). Occurrence of lysophosphatidic acid and its alkyl ether-linked analog in rat brain and comparison of their biological activities toward cultured neural cells. Biochem. Biophys. Acta 1440, 194-204.
    • (1999) Biochem. Biophys. Acta , vol.1440 , pp. 194-204
    • Sugiura, T.1    Nakane, S.2    Kishimoto, S.3    Waku, K.4    Yoshioka, Y.5    Tokumura, A.6    Hanahan, D.J.7
  • 57
    • 43249104379 scopus 로고    scopus 로고
    • Application of machine learning algorithms to predict coronary artery calcification with a sibship-based design
    • Sun, Y. V., Bielak, L. F., Peyser, P. A., Turner, S. T., Sheedy, P. F. II., Boerwinkle, E., and Kardia, S. L. (2008). Application of machine learning algorithms to predict coro-nary artery calcification with a sibship-based design. Genet. Epi-demiol. 32, 350-360.
    • (2008) Genet. Epi-demiol. , vol.32 , pp. 350-360
    • Sun, Y.V.1    Bielak, L.F.2    Peyser, P.A.3    Turner, S.T.4    Sheedy, P.F.5    Boerwinkle II, E.6    Kardia, S.L.7
  • 58
    • 60149112585 scopus 로고    scopus 로고
    • Regulation and physiological functions of G12/13-mediated signaling pathways
    • Suzuki, N., Hajicek, N., and Kozasa, T. (2009). Regulation and physiolog-ical functions of G12/13-mediated signaling pathways. Neurosignals 17, 55-70.
    • (2009) Neurosignals , vol.17 , pp. 55-70
    • Suzuki, N.1    Hajicek, N.2    Kozasa, T.3
  • 59
    • 33748314488 scopus 로고    scopus 로고
    • Zaprinast, a well-known cyclic guanosine monophosphate-specific phospho-diesterase inhibitor, is an agonist for GPR35
    • Taniguchi, Y., Tonai-Kachi, H., and Shinjo, K. (2006). Zaprinast, a well-known cyclic guanosine monophosphate-specific phospho-diesterase inhibitor, is an agonist for GPR35. FEBS Lett. 580, 5003-5008.
    • (2006) FEBS Lett , vol.580 , pp. 5003-5008
    • Taniguchi, Y.1    Tonai-Kachi, H.2    Shinjo, K.3
  • 60
    • 52349100277 scopus 로고    scopus 로고
    • 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a GPR35 agonist
    • Taniguchi, Y., Tonai-Kachi, H., and Shinjo, K. (2008). 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a GPR35 agonist. Pharmacology 82, 245-249.
    • (2008) Pharmacology , vol.82 , pp. 245-249
    • Taniguchi, Y.1    Tonai-Kachi, H.2    Shinjo, K.3
  • 61
    • 0037458614 scopus 로고    scopus 로고
    • The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional conse-quence of ERK activation
    • Tohgo, A., Choy, E. W., Gesty-Palmer, D., Pierce, K. L., Laporte, S., Oakley, R. H., Caron, M. G., Lefkowitz, R. J., and Luttell, L. M. (2003). The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional conse-quence of ERK activation. J. Biol. Chem. 278, 6258-6267.
    • (2003) J. Biol. Chem. , vol.278 , pp. 6258-6267
    • Tohgo, A.1    Choy, E.W.2    Gesty-Palmer, D.3    Pierce, K.L.4    Laporte, S.5    Oakley, R.H.6    Caron, M.G.7    Lefkowitz, R.J.8    Luttell, L.M.9
  • 66
  • 67
    • 31344432451 scopus 로고    scopus 로고
    • Antinociceptive effects and synergistic interaction with morphine of intrathecal metabotropic glutamate receptor 2/3 antagonist in the formalin test of rats
    • Yoon, M. H., Choi, J., Bae, H. B., Kim, S. J., Chung, S. T., Jeong, S. W., Chung, S. S., Yoo, K. Y., and Jeong, C. Y. (2006). Antinociceptive effects and synergistic interaction with mor-phine of intrathecal metabotropic glutamate receptor 2/3 antagonist in the formalin test of rats. Neurosci. Lett. 394, 222-226.
    • (2006) Neurosci. Lett. , vol.394 , pp. 222-226
    • Yoon, M.H.1    Choi, J.2    Bae, H.B.3    Kim, S.J.4    Chung, S.T.5    Jeong, S.W.6    Chung, S.S.7    Yoo, K.Y.8    Jeong, C.Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.