Environmental contaminant mixtures at ambient concentrations invoke a metabolic stress response in goldfish not predicted from exposure to individual compounds alone

Journal of Proteome Research

Volumn 11, Issue 2, 2012, Pages 1133-1143

  Jordan, Julia ^a   Zare, Ava ^a   Jackson, Leland J ^a   Habibi, Hamid R ^a   Weljie, Aalim M ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

1H NMR spectroscopy; chemometrics; endocrine disruption; environmental toxicology; integrative metabolomics; stress response; toxicant mixtures; toxicometabolomics

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ADENYLATE KINASE; CYCLIC AMP; NONYLPHENOL; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; ECOTOXICOLOGY; ENERGY METABOLISM; ENVIRONMENTAL EXPOSURE; GOLDFISH; GONAD; IN VIVO STUDY; LIPID METABOLISM; LIVER; MALE; METABOLIC STRESS; METABOLOMICS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RISK ASSESSMENT; SIGNAL TRANSDUCTION; STRESS; WATER POLLUTANT;

ANIMALS; DRUG SYNERGISM; ECOTOXICOLOGY; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; FEMALE; GOLDFISH; LIVER; MALE; METABOLOME; METABOLOMICS; PHENOLS; PHTHALIC ACIDS; STRESS, PHYSIOLOGICAL; TESTIS; TOXICITY TESTS; WATER POLLUTANTS, CHEMICAL;

ANIMALIA; CARASSIUS AURATUS;

EID: 84856660569     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200840b     Document Type: Article

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