Peroxisome proliferator-activated receptor-γ mediates bisphenol A inhibition of FSH-stimulated IGF-1, aromatase, and estradiol in human granulosa cells

Environmental Health Perspectives

Volumn 118, Issue 3, 2010, Pages 400-406

  Kwintkiewicz, Jakub ^a   Nishi, Yoshihiro ^b   Yanase, Toshihiko ^c   Giudice, Linda C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Aromatase; Bisphenol A; Estradiol; FSH; Granulosa; IGF 1, ovary; PPAR

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; AROMATASE; AROMATASE INHIBITOR; CELL DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENDOCRINE DISRUPTOR; ESTRADIOL; FOLLITROPIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SOMATOMEDIN; STEROIDOGENIC FACTOR 1; SYNAPSIN I; TRANSCRIPTION FACTOR GATA 4;

APOPTOSIS; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; DNA FRAGMENTATION; DNA SYNTHESIS; DOSE RESPONSE; DOWN REGULATION; EXPRESSION VECTOR; FERTILIZATION IN VITRO; GRANULOSA CELL; HORMONE RELEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEROIDOGENESIS; UPREGULATION;

AROMATASE; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; ESTRADIOL; FEMALE; FOLLICLE STIMULATING HORMONE; GRANULOSA CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; PHENOLS; PPAR GAMMA; TIME FACTORS;

EID: 77649228470     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0901161     Document Type: Article

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