메뉴 건너뛰기




Volumn 208, Issue , 2012, Pages 79-94

Physiological role of g-protein coupled receptor phosphorylation

Author keywords

Bar code; G protein coupled receptor; G protein coupled receptor kinase; Phosphorylation

Indexed keywords

G PROTEIN COUPLED RECEPTOR; RETINA S ANTIGEN; RHODOPSIN; LIGAND; PROTEIN KINASE;

EID: 84856652508     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-642-23274-9_5     Document Type: Article
Times cited : (33)

References (68)
  • 5
    • 0033617443 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase pathway by a Gq/11-coupled muscarinic receptor is independent of receptor internalization
    • Budd DC, Rae A, Tobin AB (1999) Activation of the mitogen-activated protein kinase pathway by a Gq/11-coupled muscarinic receptor is independent of receptor internalization. J Biol Chem 274:12355-12360
    • (1999) J. Biol. Chem. , vol.274 , pp. 12355-12360
    • Budd, D.C.1    Rae, A.2    Tobin, A.B.3
  • 6
    • 77951230331 scopus 로고    scopus 로고
    • Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling
    • Busillo JM, Armando S, Sengupta R, Meucci O, Bouvier M, Benovic JL (2010) Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. J Biol Chem 285(10):7805-7817
    • (2010) J. Biol. Chem. , vol.285 , Issue.10 , pp. 7805-7817
    • Busillo, J.M.1    Armando, S.2    Sengupta, R.3    Meucci, O.4    Bouvier, M.5    Benovic, J.L.6
  • 8
    • 0037177901 scopus 로고    scopus 로고
    • 2-adrenergic receptor in response to insulin
    • DOI 10.1074/jbc.M108771200
    • Doronin S, Shumay E, Wang HY, Malbon CC (2002) Akt mediates sequestration of the beta(2)- adrenergic receptor in response to insulin. J Biol Chem 277:15124-15131 (Pubitemid 34952591)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.17 , pp. 15124-15131
    • Doronin, S.1    Shumay, E.2    Wang, H.-Y.3    Malbon, C.C.4
  • 10
    • 33744510095 scopus 로고    scopus 로고
    • 3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
    • DOI 10.1016/j.cmet.2006.04.009, PII S1550413106001288
    • Gautam D, Han SJ, Hamdan FF, Jeon J, Li B, Li JH, Cui Y, Mears D, Lu H, Deng C, Heard T, Wess J (2006) A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo. Cell Metab 3:449-461 (Pubitemid 43811775)
    • (2006) Cell Metabolism , vol.3 , Issue.6 , pp. 449-461
    • Gautam, D.1    Han, S.-J.2    Hamdan, F.F.3    Jeon, J.4    Li, B.5    Li, J.H.6    Cui, Y.7    Mears, D.8    Lu, H.9    Deng, C.10    Heard, T.11    Wess, J.12
  • 11
    • 33644552719 scopus 로고    scopus 로고
    • G-protein-coupled receptors and tyrosine kinases: Crossroads in cell signaling and regulation
    • Gavi S, Shumay E, Wang HY, Malbon CC (2006) G-protein-coupled receptors and tyrosine kinases: crossroads in cell signaling and regulation. Trends Endocrinol Metab 17:48-54
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 48-54
    • Gavi, S.1    Shumay, E.2    Wang, H.Y.3    Malbon, C.C.4
  • 12
    • 79953902541 scopus 로고    scopus 로고
    • Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation
    • Ghosh M, Schonbrunn A (2011) Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation. J Biol Chem 286:13561-13573
    • (2011) J. Biol. Chem. , vol.286 , pp. 13561-13573
    • Ghosh, M.1    Schonbrunn, A.2
  • 13
    • 0034786750 scopus 로고    scopus 로고
    • Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function
    • DOI 10.1210/er.22.5.565
    • Gilon P, Henquin JC (2001) Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function. Endocr Rev 22:565-604 (Pubitemid 32958576)
    • (2001) Endocrine Reviews , vol.22 , Issue.5 , pp. 565-604
    • Gilon, P.1    Henquin, J.-C.2
  • 14
    • 33744506842 scopus 로고    scopus 로고
    • 3 receptor activity in the control of pancreatic beta cell function
    • DOI 10.1016/j.cmet.2006.05.004, PII S1550413106001598
    • Gromada J, Hughes TE (2006) Ringing the dinner bell for insulin: muscarinic M3 receptor activity in the control of pancreatic beta cell function. Cell Metab 3:390-392 (Pubitemid 43811781)
    • (2006) Cell Metabolism , vol.3 , Issue.6 , pp. 390-392
    • Gromada, J.1    Hughes, T.E.2
  • 15
    • 0842331059 scopus 로고    scopus 로고
    • The molecular acrobatics of arrestin activation
    • DOI 10.1016/j.tips.2003.12.008
    • Gurevich VV, Gurevich EV (2004) The molecular acrobatics of arrestin activation. Trends Pharmacol Sci 25:105-111 (Pubitemid 38183397)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.2 , pp. 105-111
    • Gurevich, V.V.1    Gurevich, E.V.2
  • 16
    • 33845870964 scopus 로고    scopus 로고
    • Arrestins: Ubiquitous regulators of cellular signaling pathways
    • Gurevich EV, Gurevich VV (2006a) Arrestins: ubiquitous regulators of cellular signaling pathways. Genome Biol 7:236
    • (2006) Genome. Biol. , vol.7 , pp. 236
    • Gurevich, E.V.1    Gurevich, V.V.2
  • 17
    • 33646414189 scopus 로고    scopus 로고
    • The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
    • Gurevich VV, Gurevich EV (2006b) The structural basis of arrestin-mediated regulation of G-protein-coupled receptors. Pharmacol Ther 110:465-502
    • (2006) Pharmacol. Ther. , vol.110 , pp. 465-502
    • Gurevich, V.V.1    Gurevich, E.V.2
  • 18
    • 0030066616 scopus 로고    scopus 로고
    • Phosphorylation of human m1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 and protein kinase C
    • DOI 10.1074/jbc.271.5.2776
    • Haga K, Kameyama K, Haga T, Kikkawa U, Shiozaki K, Uchiyama H (1996) Phosphorylation of human m1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 and protein kinase C. J Biol Chem 271:2776-2782 (Pubitemid 26047896)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.5 , pp. 2776-2782
    • Haga, K.1    Kameyama, K.2    Haga, T.3    Kikkawal, U.4    Shiozaki, K.5    Uchiyama, H.6
  • 20
    • 0033574274 scopus 로고    scopus 로고
    • The 2.8 A crystal structure of visual arrestin: A model for arrestis regulation
    • Hirsch JA, Schubert C, Gurevich VV, Sigler PB (1999) The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation. Cell 97:257-269
    • (1999) Cell , vol.97 , pp. 257-269
    • Hirsch, J.A.1    Schubert, C.2    Gurevich, V.V.3    Sigler, P.B.4
  • 21
    • 0034885334 scopus 로고    scopus 로고
    • Multiple phosphorylation of rhodopsin and the in vivo chemistry underlying rod photoreceptor dark adaptation
    • DOI 10.1016/S0896-6273(01)00340-3
    • Kennedy MJ, Lee KA, Niemi GA, Craven KB, Garwin GG, Saari JC, Hurley JB (2001) Multiple phosphorylation of rhodopsin and the in vivo chemistry underlying rod photoreceptor dark adaptation. Neuron 31:87-101 (Pubitemid 32757091)
    • (2001) Neuron , vol.31 , Issue.1 , pp. 87-101
    • Kennedy, M.J.1    Lee, K.A.2    Niemi, G.A.3    Craven, K.B.4    Garwin, G.G.5    Saari, J.C.6    Hurley, J.B.7
  • 24
    • 0034666697 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the deltaopioid receptor evidence for its role in mitogen-activated protein kinase activation and receptor internalization
    • Kramer HK, Andria ML, Esposito DH, Simon EJ (2000) Tyrosine phosphorylation of the deltaopioid receptor. Evidence for its role in mitogen-activated protein kinase activation and receptor internalization. Biochem Pharmacol 60:781-792
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 781-792
    • Kramer, H.K.1    Andria, M.L.2    Esposito, D.H.3    Simon, E.J.4
  • 25
    • 3042798261 scopus 로고    scopus 로고
    • Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: Molecular modeling and mutagenesis approaches to receptor structure and function
    • DOI 10.1016/j.pharmthera.2004.05.002, PII S0163725804000695
    • Kristiansen K (2004) Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol Ther 103:21-80 (Pubitemid 38891912)
    • (2004) Pharmacology and Therapeutics , vol.103 , Issue.1 , pp. 21-80
    • Kristiansen, K.1
  • 26
    • 0024372284 scopus 로고
    • Phosphorylation of chick heart muscarinic cholinergic receptors by the beta-adrenergic receptor kinase
    • DOI 10.1021/bi00437a005
    • Kwatra MM, Benovic JL, Caron MG, Lefkowitz RJ, Hosey MM (1989) Phosphorylation of chick heart muscarinic cholinergic receptors by the beta-adrenergic receptor kinase. Biochemistry 28:4543-4547 (Pubitemid 19151023)
    • (1989) Biochemistry , vol.28 , Issue.11 , pp. 4543-4547
    • Kwatra, M.M.1    Benovic, J.L.2    Caron, M.G.3    Lefkowitz, R.J.4    Hosey, M.M.5
  • 29
    • 3242793327 scopus 로고    scopus 로고
    • Historical review: A brief history and personal retrospective of seven-transmembrane receptors
    • DOI 10.1016/j.tips.2004.06.006, PII S0165614704001750
    • Lefkowitz RJ (2004) Historical review: a brief history and personal retrospective of seventransmembrane receptors. Trends Pharmacol Sci 25:413-422 (Pubitemid 38981557)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.8 , pp. 413-422
    • Lefkowitz, R.J.1
  • 30
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz RJ, Shenoy SK (2005) Transduction of receptor signals by beta-arrestins. Science 308:512-517
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 31
    • 2942618584 scopus 로고    scopus 로고
    • Beta-arrestins: Traffic cops of cell signaling
    • DOI 10.1016/j.ceb.2004.01.001, PII S0955067404000055
    • Lefkowitz RJ, Whalen EJ (2004) beta-arrestins: traffic cops of cell signaling. Curr Opin Cell Biol 16:162-168 (Pubitemid 38757292)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.2 , pp. 162-168
    • Lefkowitz, R.J.1    Whalen, E.J.2
  • 32
    • 38549090808 scopus 로고    scopus 로고
    • Distinct phosphorylation sites in the SSt2A somatostatin receptor control internalization, desensitization, and arrestin binding
    • DOI 10.1124/mol.107.038570
    • Liu Q, Dewi DA, Liu W, Bee MS, Schonbrunn A (2008) Distinct phosphorylation sites in the SST2A somatostatin receptor control internalization, desensitization, and arrestin binding. Mol Pharmacol 73:292-304 (Pubitemid 351159201)
    • (2008) Molecular Pharmacology , vol.73 , Issue.2 , pp. 292-304
    • Liu, Q.1    Dewi, D.A.2    Liu, W.3    Bee, M.S.4    Schonbrunn, A.5
  • 33
    • 0026640659 scopus 로고
    • Receptor-specific desensitization with purified proteins Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems
    • Lohse MJ, Andexinger S, Pitcher J, Trukawinski S, Codina J, Faure JP, Caron MG, Lefkowitz RJ (1992) Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems. J Biol Chem 267:8558-8564
    • (1992) J. Biol. Chem. , vol.267 , pp. 8558-8564
    • Lohse, M.J.1    Andexinger, S.2    Pitcher, J.3    Trukawinski, S.4    Codina, J.5    Faure, J.P.6    Caron, M.G.7    Lefkowitz, R.J.8
  • 34
    • 47849128759 scopus 로고    scopus 로고
    • M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms
    • Luo J, Busillo JM, Benovic JL (2008) M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms. Mol Pharmacol 74:338-347
    • (2008) Mol. Pharmacol. , vol.74 , pp. 338-347
    • Luo, J.1    Busillo, J.M.2    Benovic, J.L.3
  • 35
    • 7944226933 scopus 로고    scopus 로고
    • Not so strange bedfellows: G-protein-coupled receptors and Src family kinases
    • DOI 10.1038/sj.onc.1208162
    • Luttrell DK, Luttrell LM (2004) Not so strange bedfellows: G-protein-coupled receptors and Src family kinases. Oncogene 23:7969-7978 (Pubitemid 39468855)
    • (2004) Oncogene , vol.23 , Issue.REV. ISS. 7 , pp. 7969-7978
    • Luttrell, D.K.1    Luttrell, L.M.2
  • 36
    • 0035824563 scopus 로고    scopus 로고
    • Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting
    • Marchese A, Benovic JL (2001) Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting. J Biol Chem 276:45509-45512
    • (2001) J. Biol. Chem. , vol.276 , pp. 45509-45512
    • Marchese, A.1    Benovic, J.L.2
  • 38
    • 33846834013 scopus 로고    scopus 로고
    • Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins
    • DOI 10.1126/science.1134562
    • Nelson CD, Perry SJ, Regier DS, Prescott SM, Topham MK, Lefkowitz RJ (2007) Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins. Science 315:663-666 (Pubitemid 46214713)
    • (2007) Science , vol.315 , Issue.5812 , pp. 663-666
    • Nelson, C.D.1    Perry, S.J.2    Regier, D.S.3    Prescott, S.M.4    Topham, M.K.5    Lefkowitz, R.J.6
  • 39
    • 33750456519 scopus 로고    scopus 로고
    • Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
    • DOI 10.1016/j.cell.2006.09.026, PII S0092867406012748
    • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127:635-648 (Pubitemid 44647421)
    • (2006) Cell , vol.127 , Issue.3 , pp. 635-648
    • Olsen, J.V.1    Blagoev, B.2    Gnad, F.3    Macek, B.4    Kumar, C.5    Mortensen, P.6    Mann, M.7
  • 40
    • 0025742855 scopus 로고
    • Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase
    • Onorato JJ, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL (1991) Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase. Biochemistry 30:5118-5125
    • (1991) Biochemistry , vol.30 , pp. 5118-5125
    • Onorato, J.J.1    Palczewski, K.2    Regan, J.W.3    Caron, M.G.4    Lefkowitz, R.J.5    Benovic, J.L.6
  • 41
    • 0032742818 scopus 로고    scopus 로고
    • Trafficking of the HIV coreceptor CXCR4 role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization
    • Orsini MJ, Parent JL, Mundell SJ, Marchese A, Benovic JL (1999) Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization. J Biol Chem 274:31076-31086
    • (1999) J. Biol. Chem. , vol.274 , pp. 31076-31086
    • Orsini, M.J.1    Parent, J.L.2    Mundell, S.J.3    Marchese, A.4    Benovic, J.L.5
  • 48
    • 79953213342 scopus 로고    scopus 로고
    • Arrestin-rhodopsin binding stoichiometry in isolated rod outer segment membranes depends on the percentage of activated receptors
    • Sommer ME, Hofmann KP, Heck M (2011) Arrestin-rhodopsin binding stoichiometry in isolated rod outer segment membranes depends on the percentage of activated receptors. J Biol Chem 286:7359-7369
    • (2011) J. Biol. Chem. , vol.286 , pp. 7359-7369
    • Sommer, M.E.1    Hofmann, K.P.2    Heck, M.3
  • 49
    • 78650937357 scopus 로고    scopus 로고
    • Arrestin-1 expression level in rods: Balancing functional performance and photoreceptor health
    • Song X, Vishnivetskiy SA, Seo J, Chen J, Gurevich EV, Gurevich VV (2011) Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health. Neuroscience 174:37-49
    • (2011) Neuroscience , vol.174 , pp. 37-49
    • Song, X.1    Vishnivetskiy, S.A.2    Seo, J.3    Chen, J.4    Gurevich, E.V.5    Gurevich, V.V.6
  • 50
    • 40349088827 scopus 로고    scopus 로고
    • G-protein-coupled receptor phosphorylation: Where, when and by whom
    • DOI 10.1038/sj.bjp.0707662, PII 0707662
    • Tobin AB (2008) G-protein-coupled receptor phosphorylation: where, when and by whom. Br J Pharmacol 153(Suppl 1):S167-S176 (Pubitemid 351341015)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.SUPPL. 1
    • Tobin, A.B.1
  • 51
    • 0030760308 scopus 로고    scopus 로고
    • Stimulus-dependent phosphorylation of G-protein-coupled receptors by casein kinase 1a
    • DOI 10.1074/jbc.272.33.20844
    • Tobin AB, Totty NF, Sterlin AE, Nahorski SR (1997) Stimulus-dependent phosphorylation of G-protein-coupled receptors by casein kinase 1alpha. J Biol Chem 272:20844-20849 (Pubitemid 27355654)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.33 , pp. 20844-20849
    • Tobin, A.B.1    Totty, N.F.2    Sterlin, A.E.3    Nahorski, S.R.4
  • 52
    • 47849101639 scopus 로고    scopus 로고
    • Location location location site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signaling
    • Tobin AB, Butcher AJ, Kong KC (2008) Location, location, location. site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling. Trends Pharmacol Sci 29:413-420
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 413-420
    • Tobin, A.B.1    Butcher, A.J.2    Kong, K.C.3
  • 54
    • 1642576974 scopus 로고    scopus 로고
    • 2-Adrenergic Receptor Using Phosphoserine-Specific Antibodies
    • DOI 10.1124/mol.65.1.196
    • Tran TM, Friedman J, Qunaibi E, Baameur F, Moore RH, Clark RB (2004) Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies. Mol Pharmacol 65:196-206 (Pubitemid 38113900)
    • (2004) Molecular Pharmacology , vol.65 , Issue.1 , pp. 196-206
    • Tran, T.M.1    Friedman, J.2    Qunaibi, E.3    Baameur, F.4    Moore, R.H.5    Clark, R.B.6
  • 55
    • 17644390240 scopus 로고    scopus 로고
    • Mass spectrometric analysis of agonist effects on posttranslational modifications of the beta-2 adrenoceptor in mammalian cells
    • DOI 10.1021/bi0475469
    • Trester-Zedlitz M, Burlingame A, Kobilka B, von Zastrow M (2005) Mass spectrometric analysis of agonist effects on posttranslational modifications of the beta-2 adrenoceptor in mammalian cells. Biochemistry 44:6133-6143 (Pubitemid 40570706)
    • (2005) Biochemistry , vol.44 , Issue.16 , pp. 6133-6143
    • Trester-Zedlitz, M.1    Burlingame, A.2    Kobilka, B.3    Von Zastrow, M.4
  • 56
    • 0031910017 scopus 로고    scopus 로고
    • Sequestration of human muscarinic acetylcholine receptor hm1-hm5 subtypes: Effect of G protein-coupled receptor kinases GRK2, GRK4, GRK5 and GRK6
    • Tsuga H, Okuno E, Kameyama K, Haga T (1998) Sequestration of human muscarinic acetylcholine receptor hm1-hm5 subtypes: effect of G protein-coupled receptor kinases GRK2, GRK4, GRK5 and GRK6. J Pharmacol Exp Ther 284:1218-1226 (Pubitemid 28130854)
    • (1998) Journal of Pharmacology and Experimental Therapeutics , vol.284 , Issue.3 , pp. 1218-1226
    • Tsuga, H.1    Okuno, E.2    Kameyama, K.3    Haga, T.4
  • 57
    • 34447649922 scopus 로고    scopus 로고
    • Beta-arrestin-biased ligands at seven-transmembrane receptors
    • Violin JD, Lefkowitz RJ (2007) Beta-arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol Sci 28:416-422
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 416-422
    • Violin, J.D.1    Lefkowitz, R.J.2
  • 58
    • 33746012381 scopus 로고    scopus 로고
    • 2-adrenergic receptor revealed by fluorescence resonance energy transfer
    • DOI 10.1074/jbc.M513605200
    • Violin JD, Ren XR, Lefkowitz RJ (2006) G-protein-coupled receptor kinase specificity for betaarrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer. J Biol Chem 281:20577-20588 (Pubitemid 44065829)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.29 , pp. 20577-20588
    • Violin, J.D.1    Ren, X.-R.2    Lefkowitz, R.J.3
  • 61
    • 79959862379 scopus 로고    scopus 로고
    • Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins
    • Vishnivetskiy SA, Gimenez LE, Francis DJ, Hunson SM, Hubbell WL, Klug CS, Gurevich VV (2011) Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins. J Biol Chem 286(27):24288-24299
    • (2011) J. Biol. Chem. , vol.286 , Issue.27 , pp. 24288-24299
    • Vishnivetskiy, S.A.1    Gimenez, L.E.2    Francis, D.J.3    Hunson, S.M.4    Hubbell, W.L.5    Klug, C.S.6    Gurevich, V.V.7
  • 62
    • 0034680908 scopus 로고    scopus 로고
    • Insulin activation of mitogen-activated protein kinases Erk12 is amplified via beta-adrenergic receptor expression and requires the integrity of the Tyr350 of the receptor
    • Wang H, Doronin S, Malbon CC (2000) Insulin activation of mitogen-activated protein kinases Erk1,2 is amplified via beta-adrenergic receptor expression and requires the integrity of the Tyr350 of the receptor. J Biol Chem 275:36086-36093
    • (2000) J. Biol. Chem. , vol.275 , pp. 36086-36093
    • Wang, H.1    Doronin, S.2    Malbon, C.C.3
  • 63
    • 2442745350 scopus 로고    scopus 로고
    • Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors
    • DOI 10.1042/0264-6021:3380175
    • Waugh MG, Challiss RA, Berstein G, Nahorski SR, Tobin AB (1999) Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors. Biochem J 338(Pt 1):175-183 (Pubitemid 29097301)
    • (1999) Biochemical Journal , vol.338 , Issue.1 , pp. 175-183
    • Waugh, M.G.1    John Challiss, R.A.2    Berstein, G.3    Nahorski, S.R.4    Tobin, A.B.5
  • 64
    • 79952488185 scopus 로고    scopus 로고
    • Therapeutic potential of beta-arrestin- and G protein-biased agonists
    • Whalen EJ, Rajagopal S, Lefkowitz RJ (2011) Therapeutic potential of beta-arrestin- and G protein-biased agonists. Trends Mol Med 17:126-139
    • (2011) Trends Mol. Med. , vol.17 , pp. 126-139
    • Whalen, E.J.1    Rajagopal, S.2    Lefkowitz, R.J.3
  • 65
    • 0037013186 scopus 로고    scopus 로고
    • 3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells
    • DOI 10.1074/jbc.M111217200
    • Willets JM, Challiss RA, Nahorski SR (2002) Endogenous G protein-coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells. J Biol Chem 277:15523-15529 (Pubitemid 34967819)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.18 , pp. 15523-15529
    • Willets, J.M.1    John Challiss, R.A.2    Nahorski, S.R.3
  • 66
    • 0142148103 scopus 로고    scopus 로고
    • 3 Muscarinic Acetylcholine Receptor Signaling
    • DOI 10.1124/mol.64.5.1059
    • Willets JM, Mistry R, Nahorski SR, Challiss RA (2003) Specificity of g protein-coupled receptor kinase 6-mediated phosphorylation and regulation of single-cell m3 muscarinic acetylcholine receptor signaling. Mol Pharmacol 64:1059-1068 (Pubitemid 37310738)
    • (2003) Molecular Pharmacology , vol.64 , Issue.5 , pp. 1059-1068
    • Willets, J.M.1    Mistry, R.2    Nahorski, S.R.3    Challiss, R.A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.