Targeting bone as a therapy for myeloma

Cancer Microenvironment

Volumn 4, Issue 3, 2011, Pages 299-311

  Wu, Ping ^a   Morgan, Gareth J ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Bone disease; Multiple myeloma; Osteoblast; Osteoclast; Therapy

Indexed keywords

B CELL ACTIVATING FACTOR; BETA CATENIN; BHQ 880; BISPHOSPHONIC ACID DERIVATIVE; BORTEZOMIB; CYCLIN D1; CYCLIN D2; DENOSUMAB; DEXAMETHASONE; DICKKOPF 1 PROTEIN; FRIZZLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOGEN SYNTHASE KINASE 3BETA INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; LENALIDOMIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MELPHALAN; MITOGEN ACTIVATED PROTEIN KINASE; NEUTRALIZING ANTIBODY; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PAMIDRONIC ACID; PLACEBO; SCLEROSTIN; THALIDOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN; ZOLEDRONIC ACID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BONE CANCER; BONE MARROW STROMAL CELL; BONE METASTASIS; CELL DIFFERENTIATION; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; DRUG POTENTIATION; HUMAN; INTRACELLULAR SIGNALING; MESENCHYMAL STEM CELL; MULTIPLE MYELOMA; MYELOMA; MYELOMA BONE DISEASE; MYELOMA CELL; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OVERALL SURVIVAL; PLASMA CELL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; REVIEW; TUMOR MICROENVIRONMENT;

EID: 84856503238     PISSN: 18752292     EISSN: 18752284     Source Type: Journal    
DOI: 10.1007/s12307-011-0079-2     Document Type: Review

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