-
1
-
-
0030041147
-
Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-κB
-
Chauhan D, Uchiyama H, Akbarali Y, et al. Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-κB. Blood 1996;87:1104-12.
-
(1996)
Blood
, vol.87
, pp. 1104-1112
-
-
Chauhan, D.1
Uchiyama, H.2
Akbarali, Y.3
-
2
-
-
1942425110
-
Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines
-
Nefedova Y, Cheng P, Alsina M, Dalton WS, Gabrilovich DI. Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines. Blood 2004;103:3503-10.
-
(2004)
Blood
, vol.103
, pp. 3503-3510
-
-
Nefedova, Y.1
Cheng, P.2
Alsina, M.3
Dalton, W.S.4
Gabrilovich, D.I.5
-
3
-
-
0035880256
-
Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
-
Podar K, Tai YT, Davies FE, et al. Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration. Blood 2001;98:428-35.
-
(2001)
Blood
, vol.98
, pp. 428-435
-
-
Podar, K.1
Tai, Y.T.2
Davies, F.E.3
-
4
-
-
0042008128
-
Survival and proliferation factors of normal and malignant plasma cells
-
Klein B, Tarte K, Jourdan M, et al. Survival and proliferation factors of normal and malignant plasma cells. Int J Hematol 2003;78:106-13.
-
(2003)
Int J Hematol
, vol.78
, pp. 106-113
-
-
Klein, B.1
Tarte, K.2
Jourdan, M.3
-
5
-
-
0035211881
-
Novel therapies targeting the myeloma cell and its bone marrow microenvironment
-
Hideshima T, Chauhan D, Podar K, Schlossman RL, Richardson P, Anderson KC. Novel therapies targeting the myeloma cell and its bone marrow microenvironment. Semin Oncol 2001;28:607-12.
-
(2001)
Semin Oncol
, vol.28
, pp. 607-612
-
-
Hideshima, T.1
Chauhan, D.2
Podar, K.3
Schlossman, R.L.4
Richardson, P.5
Anderson, K.C.6
-
6
-
-
0036884062
-
Molecular mechanisms of novel therapeutic approaches for multiple myeloma
-
Hideshima T, Anderson KC. Molecular mechanisms of novel therapeutic approaches for multiple myeloma. Nat Rev Cancer 2002;2:927-37.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 927-937
-
-
Hideshima, T.1
Anderson, K.C.2
-
7
-
-
0034331194
-
Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
-
Hideshima T, Chauhan D, Shima Y, et al. Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy. Blood 2000;96:2943-50.
-
(2000)
Blood
, vol.96
, pp. 2943-2950
-
-
Hideshima, T.1
Chauhan, D.2
Shima, Y.3
-
8
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
Hideshima T, Richardson P, Chauhan D, et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001;61:3071-6.
-
(2001)
Cancer Res
, vol.61
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
-
9
-
-
28844490092
-
Management of the relapsed/refractory myeloma patient: Strategies incorporating lenalidomide
-
Richardson P. Management of the relapsed/refractory myeloma patient: strategies incorporating lenalidomide. Semin Hematol 2005;42:S9-15.
-
(2005)
Semin Hematol
, vol.42
-
-
Richardson, P.1
-
11
-
-
0036634390
-
BAFF: A fundamental survival factor for B cells
-
Mackay F, Browning JL. BAFF: a fundamental survival factor for B cells. Nat Rev Immunol 2002;2:465-75.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 465-475
-
-
Mackay, F.1
Browning, J.L.2
-
12
-
-
0033538468
-
BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator
-
Moore PA, Belvedere O, Orr A, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999;285:260-3.
-
(1999)
Science
, vol.285
, pp. 260-263
-
-
Moore, P.A.1
Belvedere, O.2
Orr, A.3
-
13
-
-
17344380531
-
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
-
Gross JA, Johnston J, Mudri S, et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 2000;404:995-9.
-
(2000)
Nature
, vol.404
, pp. 995-999
-
-
Gross, J.A.1
Johnston, J.2
Mudri, S.3
-
14
-
-
0034601020
-
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population
-
Thompson JS, Schneider P, Kalled SL, et al. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J Exp Med 2000;192:129-35.
-
(2000)
J Exp Med
, vol.192
, pp. 129-135
-
-
Thompson, J.S.1
Schneider, P.2
Kalled, S.L.3
-
15
-
-
0035860466
-
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
-
Thompson JS, Bixler SA, Qian F, et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 2001;293:2108-11.
-
(2001)
Science
, vol.293
, pp. 2108-2111
-
-
Thompson, J.S.1
Bixler, S.A.2
Qian, F.3
-
16
-
-
0035797908
-
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
-
Yan M, Brady JR, Chan B, et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol 2001;11:1547-52.
-
(2001)
Curr Biol
, vol.11
, pp. 1547-1552
-
-
Yan, M.1
Brady, J.R.2
Chan, B.3
-
17
-
-
0032555931
-
APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth
-
Hahne M, Kataoka T, Schroter M, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med 1998;188:1185-90.
-
(1998)
J Exp Med
, vol.188
, pp. 1185-1190
-
-
Hahne, M.1
Kataoka, T.2
Schroter, M.3
-
19
-
-
0142218540
-
Actions of BAFF in B cell maturation and its effects on the development of autoimmune disease
-
Melchers F. Actions of BAFF in B cell maturation and its effects on the development of autoimmune disease. Ann Rheum Dis 2003;62 Suppl 2:ii25-7.
-
(2003)
Ann Rheum Dis
, vol.62
, Issue.SUPPL. 2
-
-
Melchers, F.1
-
20
-
-
9144220762
-
Involvement of BAFF and APRIL in the resistance to apoptosis of BCLL through an autocrine pathway
-
Kern C, Cornuel JF, Billard C, et al. Involvement of BAFF and APRIL in the resistance to apoptosis of BCLL through an autocrine pathway. Blood 2004;103:679-88.
-
(2004)
Blood
, vol.103
, pp. 679-688
-
-
Kern, C.1
Cornuel, J.F.2
Billard, C.3
-
21
-
-
1342282154
-
Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL
-
He B, Chadburn A, Jou E, Schattner EJ, Knowles DM, Cerutti A. Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL. J Immunol 2004;172:3268-79.
-
(2004)
J Immunol
, vol.172
, pp. 3268-3279
-
-
He, B.1
Chadburn, A.2
Jou, E.3
Schattner, E.J.4
Knowles, D.M.5
Cerutti, A.6
-
22
-
-
11144355586
-
BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
-
Moreaux J, Legouffe E, Jourdan E, et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 2004;103:3148-57.
-
(2004)
Blood
, vol.103
, pp. 3148-3157
-
-
Moreaux, J.1
Legouffe, E.2
Jourdan, E.3
-
23
-
-
0942298590
-
Expression of BCMA, TACI, BAFF-R in multiple myeloma: A mechanism for growth and survival
-
Novak AJ, Darce JR, Arendt BK, et al. Expression of BCMA, TACI, BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 2004;103:689-94.
-
(2004)
Blood
, vol.103
, pp. 689-694
-
-
Novak, A.J.1
Darce, J.R.2
Arendt, B.K.3
-
24
-
-
4944262288
-
Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: Correlation with disease activity and patient outcome
-
Novak AJ, Grote DM, Stenson M, et al. Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: correlation with disease activity and patient outcome. Blood 2004;104:2247-53.
-
(2004)
Blood
, vol.104
, pp. 2247-2253
-
-
Novak, A.J.1
Grote, D.M.2
Stenson, M.3
-
25
-
-
23044512143
-
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature
-
Moreaux J, Cremer FW, Reme T, et al. The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature. Blood 2005;106:1021-30.
-
(2005)
Blood
, vol.106
, pp. 1021-1030
-
-
Moreaux, J.1
Cremer, F.W.2
Reme, T.3
-
26
-
-
33746122751
-
Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment
-
Tai YT, Li XF, Breitkreutz I, et al. Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment. Cancer Res 2006;66:6675-82.
-
(2006)
Cancer Res
, vol.66
, pp. 6675-6682
-
-
Tai, Y.T.1
Li, X.F.2
Breitkreutz, I.3
-
27
-
-
0035068530
-
Gp130 and ras mediated signaling in human plasma cell line INA-6: A cytokine-regulated tumor model for plasmacytoma
-
Burger R, Guenther A, Bakker F, et al. Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma. Hematol J 2001;2:42-53.
-
(2001)
Hematol J
, vol.2
, pp. 42-53
-
-
Burger, R.1
Guenther, A.2
Bakker, F.3
-
28
-
-
17744413236
-
Model-based analysis of oligonucleotide arrays: Model validation, design issues and standard error application
-
RESEARCH0032
-
Li C, Hung Wong W. Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application. Genome Biol 2001;2:RESEARCH0032.
-
(2001)
Genome Biol
, vol.2
-
-
Li, C.1
Hung Wong, W.2
-
29
-
-
0023753744
-
The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
-
McCune JM, Namikawa R, Kaneshima H, Shultz LD, Lieberman M, Weissman IL. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 1988;241:1632-9.
-
(1988)
Science
, vol.241
, pp. 1632-1639
-
-
McCune, J.M.1
Namikawa, R.2
Kaneshima, H.3
Shultz, L.D.4
Lieberman, M.5
Weissman, I.L.6
-
30
-
-
0030746359
-
The development of a model for the homing of multiple myeloma cells to human bone marrow
-
Urashima M, Chen BP, Chen S, et al. The development of a model for the homing of multiple myeloma cells to human bone marrow. Blood 1997;90:754-65.
-
(1997)
Blood
, vol.90
, pp. 754-765
-
-
Urashima, M.1
Chen, B.P.2
Chen, S.3
-
31
-
-
20344381988
-
A clinically relevant SCID-hu in vivo model of human multiple myeloma
-
Tassone P, Neri P, Carrasco DR, et al. A clinically relevant SCID-hu in vivo model of human multiple myeloma. Blood 2005;106:713-6.
-
(2005)
Blood
, vol.106
, pp. 713-716
-
-
Tassone, P.1
Neri, P.2
Carrasco, D.R.3
-
32
-
-
20344385768
-
Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu in vivo model of human multiple myeloma
-
Tassone P, Neri P, Burger R, et al. Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu in vivo model of human multiple myeloma. Clin Cancer Res 2005;11:4251-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4251-4258
-
-
Tassone, P.1
Neri, P.2
Burger, R.3
-
33
-
-
0023645081
-
The human hematopoietic colony-stimulating factors
-
Clark SC, Kamen R. The human hematopoietic colony-stimulating factors. Science 1987;236:1229-37.
-
(1987)
Science
, vol.236
, pp. 1229-1237
-
-
Clark, S.C.1
Kamen, R.2
-
34
-
-
0025278415
-
Biology and clinical aspects of the hematopoietic growth factors
-
Sieff CA. Biology and clinical aspects of the hematopoietic growth factors. Annu Rev Med 1990;41:483-96.
-
(1990)
Annu Rev Med
, vol.41
, pp. 483-496
-
-
Sieff, C.A.1
-
35
-
-
0032871569
-
Advances in the biology of multiple myeloma: Therapeutic applications
-
Anderson K. Advances in the biology of multiple myeloma: therapeutic applications. Semin Oncol 1999;26:10-22.
-
(1999)
Semin Oncol
, vol.26
, pp. 10-22
-
-
Anderson, K.1
-
37
-
-
0033532634
-
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
-
Schneider P, MacKay F, Steiner V, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999;189:1747-56.
-
(1999)
J Exp Med
, vol.189
, pp. 1747-1756
-
-
Schneider, P.1
MacKay, F.2
Steiner, V.3
-
38
-
-
85047690330
-
BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
-
Avery DT, Kalled SL, Ellyard JI, et al. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest 2003;112:286-97.
-
(2003)
J Clin Invest
, vol.112
, pp. 286-297
-
-
Avery, D.T.1
Kalled, S.L.2
Ellyard, J.I.3
-
39
-
-
8444222647
-
B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers
-
Rahman ZS, Manser T. B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers. J Immunol 2004;173:6179-88.
-
(2004)
J Immunol
, vol.173
, pp. 6179-6188
-
-
Rahman, Z.S.1
Manser, T.2
-
40
-
-
0034729769
-
Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
-
Marsters SA, Yan M, Pitti RM, Haas PE, Dixit VM, Ashkenazi A. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Curr Biol 2000;10:785-8.
-
(2000)
Curr Biol
, vol.10
, pp. 785-788
-
-
Marsters, S.A.1
Yan, M.2
Pitti, R.M.3
Haas, P.E.4
Dixit, V.M.5
Ashkenazi, A.6
-
41
-
-
5644302162
-
Receptor-specific signaling for both the alternative and the canonical NF-κB activation pathways by NF-κB-inducing kinase
-
Ramakrishnan P, Wang W, Wallach D. Receptor-specific signaling for both the alternative and the canonical NF-κB activation pathways by NF-κB-inducing kinase. Immunity 2004;21:477-89.
-
(2004)
Immunity
, vol.21
, pp. 477-489
-
-
Ramakrishnan, P.1
Wang, W.2
Wallach, D.3
-
42
-
-
5644271413
-
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
-
Qian Y, Qin J, Cui G, et al. Act1, a negative regulator in CD40- and BAFF-mediated B cell survival. Immunity 2004;21:575-87.
-
(2004)
Immunity
, vol.21
, pp. 575-587
-
-
Qian, Y.1
Qin, J.2
Cui, G.3
-
43
-
-
4644240851
-
Regulation of B-cell survival by BAFF-dependent PKCδ-mediated nuclear signalling
-
Mecklenbrauker I, Kalled SL, Leitges M, Mackay F, Tarakhovsky A. Regulation of B-cell survival by BAFF-dependent PKCδ-mediated nuclear signalling. Nature 2004;431:456-61.
-
(2004)
Nature
, vol.431
, pp. 456-461
-
-
Mecklenbrauker, I.1
Kalled, S.L.2
Leitges, M.3
Mackay, F.4
Tarakhovsky, A.5
-
46
-
-
1542330894
-
Pathogenesis of myeloma bone disease
-
Roodman GD. Pathogenesis of myeloma bone disease. Blood Cells Mol Dis 2004;32:290-2.
-
(2004)
Blood Cells Mol Dis
, vol.32
, pp. 290-292
-
-
Roodman, G.D.1
-
47
-
-
1542720384
-
Cancer and the microenvironment: Myeloma-osteoclast interactions as a model
-
Yaccoby S, Wezeman MJ, Henderson A, et al. Cancer and the microenvironment: myeloma-osteoclast interactions as a model. Cancer Res 2004;64:2016-23.
-
(2004)
Cancer Res
, vol.64
, pp. 2016-2023
-
-
Yaccoby, S.1
Wezeman, M.J.2
Henderson, A.3
-
48
-
-
33745193755
-
BAFF and APRIL as osteoclast-derived survival factors for myeloma cells: A rationale for TACI-Fc treatment in patients with multiple myeloma
-
Abe M, Kido S, Hiasa M, et al. BAFF and APRIL as osteoclast-derived survival factors for myeloma cells: a rationale for TACI-Fc treatment in patients with multiple myeloma. Leukemia 2006;20:1313-5.
-
(2006)
Leukemia
, vol.20
, pp. 1313-1315
-
-
Abe, M.1
Kido, S.2
Hiasa, M.3
|