메뉴 건너뛰기




Volumn 46, Issue 2, 2010, Pages 420-429

Bortezomib and zoledronic acid on angiogenic and vasculogenic activities of bone marrow macrophages in patients with multiple myeloma

Author keywords

Angiogenesis; Bortezomib; Macrophages; Multiple myeloma; Vasculogenesis; Zoledronic acid

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BORTEZOMIB; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; VASCULOTROPIN; ZOLEDRONIC ACID;

EID: 72449165023     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2009.10.019     Document Type: Article
Times cited : (65)

References (41)
  • 1
    • 6944235003 scopus 로고    scopus 로고
    • Multiple myeloma
    • Kyle R.A., and Rajkumar S.V. Multiple myeloma. New Engl J Med 351 18 (2004) 1860-1873
    • (2004) New Engl J Med , vol.351 , Issue.18 , pp. 1860-1873
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 2
    • 33746257305 scopus 로고    scopus 로고
    • Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma
    • Ribatti D., Nico B., and Vacca A. Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma. Oncogene 25 31 (2006) 4257-4266
    • (2006) Oncogene , vol.25 , Issue.31 , pp. 4257-4266
    • Ribatti, D.1    Nico, B.2    Vacca, A.3
  • 3
    • 70349312936 scopus 로고    scopus 로고
    • The role of monocytes-macrophages in vasculogenesis in multiple myeloma
    • Ribatti D, Vacca A. The role of monocytes-macrophages in vasculogenesis in multiple myeloma. Leukemia 2009.
    • (2009) Leukemia
    • Ribatti, D.1    Vacca, A.2
  • 4
    • 38549141574 scopus 로고    scopus 로고
    • Vasculogenic mimicry by bone marrow macrophages in patients with multiple myeloma
    • Scavelli C., Nico B., Cirulli T., et al. Vasculogenic mimicry by bone marrow macrophages in patients with multiple myeloma. Oncogene 27 5 (2008) 663-674
    • (2008) Oncogene , vol.27 , Issue.5 , pp. 663-674
    • Scavelli, C.1    Nico, B.2    Cirulli, T.3
  • 5
    • 34748855636 scopus 로고    scopus 로고
    • NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases
    • Sun X.F., and Zhang H. NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases. Histol Histopathol 22 12 (2007) 1387-1398
    • (2007) Histol Histopathol , vol.22 , Issue.12 , pp. 1387-1398
    • Sun, X.F.1    Zhang, H.2
  • 6
    • 38449108124 scopus 로고    scopus 로고
    • NF-kappaB: a potential target for cancer chemoprevention and therapy
    • Sarkar F.H., and Li Y. NF-kappaB: a potential target for cancer chemoprevention and therapy. Front Biosci 13 (2008) 2950-2959
    • (2008) Front Biosci , vol.13 , pp. 2950-2959
    • Sarkar, F.H.1    Li, Y.2
  • 7
    • 5644225628 scopus 로고    scopus 로고
    • Caveolin-1 is required for vascular endothelial growth factor-triggered multiple myeloma cell migration and is targeted by bortezomib
    • Podar K., Shringarpure R., Tai Y.T., et al. Caveolin-1 is required for vascular endothelial growth factor-triggered multiple myeloma cell migration and is targeted by bortezomib. Cancer Res 64 20 (2004) 7500-7506
    • (2004) Cancer Res , vol.64 , Issue.20 , pp. 7500-7506
    • Podar, K.1    Shringarpure, R.2    Tai, Y.T.3
  • 8
    • 0037277846 scopus 로고    scopus 로고
    • The antitumor potential of bisphosphonates
    • Clezardin P. The antitumor potential of bisphosphonates. Semin Oncol 2002;29(6 Suppl 21):33-42.
    • (2002) Semin Oncol , vol.29 , Issue.6 SUPPL. 21 , pp. 33-42
    • Clezardin, P.1
  • 9
    • 31544433927 scopus 로고    scopus 로고
    • Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells
    • Roccaro A.M., Hideshima T., Raje N., et al. Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells. Cancer Res 66 1 (2006) 184-191
    • (2006) Cancer Res , vol.66 , Issue.1 , pp. 184-191
    • Roccaro, A.M.1    Hideshima, T.2    Raje, N.3
  • 10
    • 37549004818 scopus 로고    scopus 로고
    • Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma
    • Scavelli C, Di Pietro G, Cirulli T, et al. Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma. Mol Cancer Ther 2007;6(12 Pt 1):3256-62.
    • (2007) Mol Cancer Ther , vol.6 , Issue.12 PART 1 , pp. 3256-3262
    • Scavelli, C.1    Di Pietro, G.2    Cirulli, T.3
  • 11
    • 0038509089 scopus 로고    scopus 로고
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: A report of the International Myeloma Working Group
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Brit J Haematol 2003;121(5):749-57.
    • (2003) Brit J Haematol , vol.121 , Issue.5 , pp. 749-757
  • 12
    • 0022973287 scopus 로고
    • Staging and kinetics of multiple myeloma
    • Durie B.G. Staging and kinetics of multiple myeloma. Semin Oncol 13 3 (1986) 300-309
    • (1986) Semin Oncol , vol.13 , Issue.3 , pp. 300-309
    • Durie, B.G.1
  • 13
    • 18644373689 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases
    • Chen T., Berenson J., Vescio R., et al. Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases. J Clin Pharmacol 42 11 (2002) 1228-1236
    • (2002) J Clin Pharmacol , vol.42 , Issue.11 , pp. 1228-1236
    • Chen, T.1    Berenson, J.2    Vescio, R.3
  • 14
    • 0142183449 scopus 로고    scopus 로고
    • Endothelial cells in the bone marrow of patients with multiple myeloma
    • Vacca A., Ria R., Semeraro F., et al. Endothelial cells in the bone marrow of patients with multiple myeloma. Blood 102 9 (2003) 3340-3348
    • (2003) Blood , vol.102 , Issue.9 , pp. 3340-3348
    • Vacca, A.1    Ria, R.2    Semeraro, F.3
  • 15
    • 51649116942 scopus 로고    scopus 로고
    • Validation of PDGFRbeta and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib
    • Coluccia A.M., Cirulli T., Neri P., et al. Validation of PDGFRbeta and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib. Blood 112 4 (2008) 1346-1356
    • (2008) Blood , vol.112 , Issue.4 , pp. 1346-1356
    • Coluccia, A.M.1    Cirulli, T.2    Neri, P.3
  • 16
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • Chou T.C., and Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22 (1984) 27-55
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 17
    • 42049112366 scopus 로고    scopus 로고
    • Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells
    • Kawasaki K., Watabe T., Sase H., et al. Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. J Cell Biol 181 1 (2008) 131-141
    • (2008) J Cell Biol , vol.181 , Issue.1 , pp. 131-141
    • Kawasaki, K.1    Watabe, T.2    Sase, H.3
  • 18
    • 18544367201 scopus 로고    scopus 로고
    • NF-kappa B as a therapeutic target in multiple myeloma
    • Hideshima T., Chauhan D., Richardson P., et al. NF-kappa B as a therapeutic target in multiple myeloma. J Biol Chem 277 19 (2002) 16639-16647
    • (2002) J Biol Chem , vol.277 , Issue.19 , pp. 16639-16647
    • Hideshima, T.1    Chauhan, D.2    Richardson, P.3
  • 19
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson P.G., Barlogie B., Berenson J., et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. New Engl J Med 348 26 (2003) 2609-2617
    • (2003) New Engl J Med , vol.348 , Issue.26 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 20
    • 20144387627 scopus 로고    scopus 로고
    • Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
    • Orlowski R.Z., Voorhees P.M., Garcia R.A., et al. Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 105 8 (2005) 3058-3065
    • (2005) Blood , vol.105 , Issue.8 , pp. 3058-3065
    • Orlowski, R.Z.1    Voorhees, P.M.2    Garcia, R.A.3
  • 21
    • 43249097561 scopus 로고    scopus 로고
    • Thalidomide for treatment of multiple myeloma: 10 years later
    • Palumbo A., Facon T., Sonneveld P., et al. Thalidomide for treatment of multiple myeloma: 10 years later. Blood 111 8 (2008) 3968-3977
    • (2008) Blood , vol.111 , Issue.8 , pp. 3968-3977
    • Palumbo, A.1    Facon, T.2    Sonneveld, P.3
  • 22
    • 0142186217 scopus 로고    scopus 로고
    • A prospective, open-label safety and efficacy study of combination treatment with bortezomib (PS-341), velcade and melphalan in patients with relapsed or refractory multiple myeloma
    • Yang H.H., Vescio R., Schenkein D., and Berenson J.R. A prospective, open-label safety and efficacy study of combination treatment with bortezomib (PS-341), velcade and melphalan in patients with relapsed or refractory multiple myeloma. Clin Lymphoma 4 2 (2003) 119-122
    • (2003) Clin Lymphoma , vol.4 , Issue.2 , pp. 119-122
    • Yang, H.H.1    Vescio, R.2    Schenkein, D.3    Berenson, J.R.4
  • 23
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T., Richardson P., Chauhan D., et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 61 7 (2001) 3071-3076
    • (2001) Cancer Res , vol.61 , Issue.7 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3
  • 24
    • 40349114898 scopus 로고    scopus 로고
    • Zoledronic acid: a review of its use in the management of bone metastases of malignancy
    • Dhillon S., and Lyseng-Williamson K.A. Zoledronic acid: a review of its use in the management of bone metastases of malignancy. Drugs 68 4 (2008) 507-534
    • (2008) Drugs , vol.68 , Issue.4 , pp. 507-534
    • Dhillon, S.1    Lyseng-Williamson, K.A.2
  • 25
    • 60549097419 scopus 로고    scopus 로고
    • Endocrine therapy plus zoledronic acid in premenopausal breast cancer
    • Gnant M., Mlineritsch B., Schippinger W., et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. New Engl J Med 360 7 (2009) 679-691
    • (2009) New Engl J Med , vol.360 , Issue.7 , pp. 679-691
    • Gnant, M.1    Mlineritsch, B.2    Schippinger, W.3
  • 26
    • 27944479578 scopus 로고    scopus 로고
    • Prostate cancer presenting with normal serum PSA levels and boney metastases treated with zoledronic acid
    • Mystakidou K., Katsouda E., Parpa E., and Vlahos L. Prostate cancer presenting with normal serum PSA levels and boney metastases treated with zoledronic acid. J Pain Palliat Care Pharmacother 19 3 (2005) 41-45
    • (2005) J Pain Palliat Care Pharmacother , vol.19 , Issue.3 , pp. 41-45
    • Mystakidou, K.1    Katsouda, E.2    Parpa, E.3    Vlahos, L.4
  • 27
    • 0033972908 scopus 로고    scopus 로고
    • Oral bisphosphonates: a review of clinical use in patients with bone metastases
    • Major P.P., Lipton A., Berenson J., and Hortobagyi G. Oral bisphosphonates: a review of clinical use in patients with bone metastases. Cancer 88 1 (2000) 6-14
    • (2000) Cancer , vol.88 , Issue.1 , pp. 6-14
    • Major, P.P.1    Lipton, A.2    Berenson, J.3    Hortobagyi, G.4
  • 29
    • 13544255403 scopus 로고    scopus 로고
    • The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications
    • Podar K., and Anderson K.C. The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications. Blood 105 4 (2005) 1383-1395
    • (2005) Blood , vol.105 , Issue.4 , pp. 1383-1395
    • Podar, K.1    Anderson, K.C.2
  • 30
    • 0038284068 scopus 로고    scopus 로고
    • A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma
    • Vacca A., Ria R., Ribatti D., et al. A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma. Haematologica 88 2 (2003) 176-185
    • (2003) Haematologica , vol.88 , Issue.2 , pp. 176-185
    • Vacca, A.1    Ria, R.2    Ribatti, D.3
  • 31
    • 69749110704 scopus 로고    scopus 로고
    • Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro
    • Raikkonen J, Crockett JC, Rogers MJ, Monkkonen H, Auriola S, Monkkonen J. Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro. Brit J Pharmacol 2009.
    • (2009) Brit J Pharmacol
    • Raikkonen, J.1    Crockett, J.C.2    Rogers, M.J.3    Monkkonen, H.4    Auriola, S.5    Monkkonen, J.6
  • 32
    • 41849123834 scopus 로고    scopus 로고
    • Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase
    • Dunford J.E., Kwaasi A.A., Rogers M.J., et al. Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase. J Med Chem 51 7 (2008) 2187-2195
    • (2008) J Med Chem , vol.51 , Issue.7 , pp. 2187-2195
    • Dunford, J.E.1    Kwaasi, A.A.2    Rogers, M.J.3
  • 33
    • 20444486612 scopus 로고    scopus 로고
    • Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity
    • Clezardin P., Ebetino F.H., and Fournier P.G. Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity. Cancer Res 65 12 (2005) 4971-4974
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 4971-4974
    • Clezardin, P.1    Ebetino, F.H.2    Fournier, P.G.3
  • 34
    • 34247175312 scopus 로고    scopus 로고
    • GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
    • Bustelo X.R., Sauzeau V., and Berenjeno I.M. GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo. Bioessays 29 4 (2007) 356-370
    • (2007) Bioessays , vol.29 , Issue.4 , pp. 356-370
    • Bustelo, X.R.1    Sauzeau, V.2    Berenjeno, I.M.3
  • 35
    • 0034902354 scopus 로고    scopus 로고
    • Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
    • Sunwoo J.B., Chen Z., Dong G., et al. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin Cancer Res 7 5 (2001) 1419-1428
    • (2001) Clin Cancer Res , vol.7 , Issue.5 , pp. 1419-1428
    • Sunwoo, J.B.1    Chen, Z.2    Dong, G.3
  • 36
    • 0035328584 scopus 로고    scopus 로고
    • Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition
    • Cusack Jr. J.C., Liu R., Houston M., et al. Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. Cancer Res 61 9 (2001) 3535-3540
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3535-3540
    • Cusack Jr., J.C.1    Liu, R.2    Houston, M.3
  • 37
    • 18644367630 scopus 로고    scopus 로고
    • The function of multiple IkappaB: NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis
    • Dong Q.G., Sclabas G.M., Fujioka S., et al. The function of multiple IkappaB: NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. Oncogene 21 42 (2002) 6510-6519
    • (2002) Oncogene , vol.21 , Issue.42 , pp. 6510-6519
    • Dong, Q.G.1    Sclabas, G.M.2    Fujioka, S.3
  • 38
    • 4644313276 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma
    • Loercher A., Lee T.L., Ricker J.L., et al. Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. Cancer Res 64 18 (2004) 6511-6523
    • (2004) Cancer Res , vol.64 , Issue.18 , pp. 6511-6523
    • Loercher, A.1    Lee, T.L.2    Ricker, J.L.3
  • 39
    • 0346122900 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma
    • Hideshima T., Chauhan D., Hayashi T., et al. Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma. Oncogene 22 52 (2003) 8386-8393
    • (2003) Oncogene , vol.22 , Issue.52 , pp. 8386-8393
    • Hideshima, T.1    Chauhan, D.2    Hayashi, T.3
  • 40
    • 0036735298 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model
    • LeBlanc R., Catley L.P., Hideshima T., et al. Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model. Cancer Res 62 17 (2002) 4996-5000
    • (2002) Cancer Res , vol.62 , Issue.17 , pp. 4996-5000
    • LeBlanc, R.1    Catley, L.P.2    Hideshima, T.3
  • 41
    • 0034759491 scopus 로고    scopus 로고
    • The proteasome in cancer biology and treatment
    • Pajonk F, McBride WH. The proteasome in cancer biology and treatment. Radiat Res 2001;156(5 Pt 1):447-59.
    • (2001) Radiat Res , vol.156 , Issue.5 PART 1 , pp. 447-459
    • Pajonk, F.1    McBride, W.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.