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Volumn 315, Issue 11, 2009, Pages 1904-1913

Mesenchymal stromal cells revert multiple myeloma cells to less differentiated phenotype by the combined activities of adhesive interactions and interleukin-6

Author keywords

Adhesion; Differentiation; Microenvironment; Multiple myeloma; Stroma

Indexed keywords

CD38 ANTIGEN; IMMUNOGLOBULIN LIGHT CHAIN; INTERLEUKIN 6; SYNDECAN 1;

EID: 67349092202     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2009.03.016     Document Type: Article
Times cited : (27)

References (42)
  • 1
    • 39349096526 scopus 로고    scopus 로고
    • Hematopoiesis: an evolving paradigm for stem cell biology
    • Orkin S.H., and Zon L.I. Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132 (2008) 631-644
    • (2008) Cell , vol.132 , pp. 631-644
    • Orkin, S.H.1    Zon, L.I.2
  • 2
    • 38049092429 scopus 로고    scopus 로고
    • CD8+ memory T lymphocytes from bone marrow-immune function and therapeutic potential
    • Wood A.H., Zhang X., Farber D.L., and Strome S.E. CD8+ memory T lymphocytes from bone marrow-immune function and therapeutic potential. Crit. Rev. Immunol. 27 (2007) 527-537
    • (2007) Crit. Rev. Immunol. , vol.27 , pp. 527-537
    • Wood, A.H.1    Zhang, X.2    Farber, D.L.3    Strome, S.E.4
  • 3
    • 33845640823 scopus 로고    scopus 로고
    • Antigen presenting cells and stromal cells trigger human natural killer lymphocytes to autoreactivity: evidence for the involvement of natural cytotoxicity receptors (NCR) and NKG2D
    • Poggi A., and Zocchi M.R. Antigen presenting cells and stromal cells trigger human natural killer lymphocytes to autoreactivity: evidence for the involvement of natural cytotoxicity receptors (NCR) and NKG2D. Clin. Dev. Immunol. 13 (2006) 325-336
    • (2006) Clin. Dev. Immunol. , vol.13 , pp. 325-336
    • Poggi, A.1    Zocchi, M.R.2
  • 4
    • 58149398636 scopus 로고    scopus 로고
    • Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts
    • Wakkach A., Mansour A., Dacquin R., Coste E., Jurdic P., Carle G.F., and Blin-Wakkach C. Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts. Blood 112 (2008) 5074-5083
    • (2008) Blood , vol.112 , pp. 5074-5083
    • Wakkach, A.1    Mansour, A.2    Dacquin, R.3    Coste, E.4    Jurdic, P.5    Carle, G.F.6    Blin-Wakkach, C.7
  • 5
    • 39649084660 scopus 로고    scopus 로고
    • Plasma cell development: from B-cell subsets to long-term survival niches
    • Fairfax K.A., Kallies A., Nutt S.L., and Tarlinton D.M. Plasma cell development: from B-cell subsets to long-term survival niches. Semin. Immunol. 20 (2008) 49-58
    • (2008) Semin. Immunol. , vol.20 , pp. 49-58
    • Fairfax, K.A.1    Kallies, A.2    Nutt, S.L.3    Tarlinton, D.M.4
  • 7
    • 37549015263 scopus 로고    scopus 로고
    • Germinal centres: role in B-cell physiology and malignancy
    • Klein U., and Dalla-Favera R. Germinal centres: role in B-cell physiology and malignancy. Nat. Rev. Immunol. 8 (2008) 22-33
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 22-33
    • Klein, U.1    Dalla-Favera, R.2
  • 9
    • 33746326785 scopus 로고    scopus 로고
    • The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: interplay of growth factors, their receptors and stromal interactions
    • Mitsiades C.S., Mitsiades N.S., Munshi N.C., Richardson P.G., and Anderson K.C. The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: interplay of growth factors, their receptors and stromal interactions. Eur. J. Cancer 42 (2006) 1564-1573
    • (2006) Eur. J. Cancer , vol.42 , pp. 1564-1573
    • Mitsiades, C.S.1    Mitsiades, N.S.2    Munshi, N.C.3    Richardson, P.G.4    Anderson, K.C.5
  • 12
    • 0034905554 scopus 로고    scopus 로고
    • The promotion of plasmacytoma tumor growth by mesenchymal stroma is antagonized by basic fibroblast growth factor induced activin A
    • Shoham T., Sternberg D., Brosh N., Krupsky M., Barda-Saad M., and Zipori D. The promotion of plasmacytoma tumor growth by mesenchymal stroma is antagonized by basic fibroblast growth factor induced activin A. Leukemia 15 (2001) 1102-1110
    • (2001) Leukemia , vol.15 , pp. 1102-1110
    • Shoham, T.1    Sternberg, D.2    Brosh, N.3    Krupsky, M.4    Barda-Saad, M.5    Zipori, D.6
  • 14
    • 38749098732 scopus 로고    scopus 로고
    • Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts
    • Chen X.D., Dusevich V., Feng J.Q., Manolagas S.C., and Jilka R.L. Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts. J. Bone Miner. Res. 22 (2007) 1943-1956
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 1943-1956
    • Chen, X.D.1    Dusevich, V.2    Feng, J.Q.3    Manolagas, S.C.4    Jilka, R.L.5
  • 16
    • 0034988303 scopus 로고    scopus 로고
    • Bone marrow stromal stem cells: nature, biology, and potential applications
    • Bianco P., Riminucci M., Gronthos S., and Robey P.G. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 19 (2001) 180-192
    • (2001) Stem Cells , vol.19 , pp. 180-192
    • Bianco, P.1    Riminucci, M.2    Gronthos, S.3    Robey, P.G.4
  • 17
    • 27744526844 scopus 로고    scopus 로고
    • The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype
    • Yaccoby S. The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype. Clin. Cancer Res. 11 (2005) 7599-7606
    • (2005) Clin. Cancer Res. , vol.11 , pp. 7599-7606
    • Yaccoby, S.1
  • 19
    • 0037108354 scopus 로고    scopus 로고
    • The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity
    • Minges Wols H.A., Underhill G.H., Kansas G.S., and Witte P.L. The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity. J. Immunol. 169 (2002) 4213-4221
    • (2002) J. Immunol. , vol.169 , pp. 4213-4221
    • Minges Wols, H.A.1    Underhill, G.H.2    Kansas, G.S.3    Witte, P.L.4
  • 21
    • 33749004025 scopus 로고    scopus 로고
    • The generation and regulation of functional diversity of malignant plasma cells
    • Nadav L., Katz B.Z., Baron S., Cohen N., Naparstek E., and Geiger B. The generation and regulation of functional diversity of malignant plasma cells. Cancer Res. 66 (2006) 8608-8616
    • (2006) Cancer Res. , vol.66 , pp. 8608-8616
    • Nadav, L.1    Katz, B.Z.2    Baron, S.3    Cohen, N.4    Naparstek, E.5    Geiger, B.6
  • 23
    • 33746378638 scopus 로고    scopus 로고
    • Signalling and survival pathways in multiple myeloma
    • Bommert K., Bargou R.C., and Stuhmer T. Signalling and survival pathways in multiple myeloma. Eur. J. Cancer 42 (2006) 1574-1580
    • (2006) Eur. J. Cancer , vol.42 , pp. 1574-1580
    • Bommert, K.1    Bargou, R.C.2    Stuhmer, T.3
  • 24
    • 0038370952 scopus 로고    scopus 로고
    • A review of the cytokine network in multiple myeloma: diagnostic, prognostic, and therapeutic implications
    • Lauta V.M. A review of the cytokine network in multiple myeloma: diagnostic, prognostic, and therapeutic implications. Cancer 97 (2003) 2440-2452
    • (2003) Cancer , vol.97 , pp. 2440-2452
    • Lauta, V.M.1
  • 27
    • 52049103847 scopus 로고    scopus 로고
    • The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
    • Meads M.B., Hazlehurst L.A., and Dalton W.S. The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance. Clin. Cancer Res. 14 (2008) 2519-2526
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2519-2526
    • Meads, M.B.1    Hazlehurst, L.A.2    Dalton, W.S.3
  • 31
    • 52349093467 scopus 로고    scopus 로고
    • Side populations-following the footprints of the elusive multiple myeloma stem cells?
    • Katz B.Z. Side populations-following the footprints of the elusive multiple myeloma stem cells?. Leuk. Lymphoma 49 (2008) 1657-1658
    • (2008) Leuk. Lymphoma , vol.49 , pp. 1657-1658
    • Katz, B.Z.1
  • 32
    • 33644644120 scopus 로고    scopus 로고
    • Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival
    • Ge Y., Zhan F., Barlogie B., Epstein J., Shaughnessy Jr. J., and Yaccoby S. Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival. Br. J. Haematol. 133 (2006) 83-92
    • (2006) Br. J. Haematol. , vol.133 , pp. 83-92
    • Ge, Y.1    Zhan, F.2    Barlogie, B.3    Epstein, J.4    Shaughnessy Jr., J.5    Yaccoby, S.6
  • 34
    • 33845535809 scopus 로고    scopus 로고
    • The mesenchyme in cancer therapy as a target tumor component, effector cell modality and cytokine expression vehicle
    • Zipori D. The mesenchyme in cancer therapy as a target tumor component, effector cell modality and cytokine expression vehicle. Cancer Metastasis Rev. 25 (2006) 459-467
    • (2006) Cancer Metastasis Rev. , vol.25 , pp. 459-467
    • Zipori, D.1
  • 35
    • 0038806506 scopus 로고    scopus 로고
    • The mesenchymal stroma negatively regulates B cell lymphopoiesis through the expression of activin A
    • Shoham T., Parameswaran R., Shav-Tal Y., Barda-Saad M., and Zipori D. The mesenchymal stroma negatively regulates B cell lymphopoiesis through the expression of activin A. Ann. N. Y. Acad. Sci. 996 (2003) 245-260
    • (2003) Ann. N. Y. Acad. Sci. , vol.996 , pp. 245-260
    • Shoham, T.1    Parameswaran, R.2    Shav-Tal, Y.3    Barda-Saad, M.4    Zipori, D.5
  • 36
    • 0034973221 scopus 로고    scopus 로고
    • Role of activin A in negative regulation of normal and tumor B lymphocytes
    • Zipori D., and Barda-Saad M. Role of activin A in negative regulation of normal and tumor B lymphocytes. J. Leukoc. Biol. 69 (2001) 867-873
    • (2001) J. Leukoc. Biol. , vol.69 , pp. 867-873
    • Zipori, D.1    Barda-Saad, M.2
  • 38
    • 33845285214 scopus 로고    scopus 로고
    • Synopsis of a roundtable on validating novel therapeutics for multiple myeloma
    • Dalton W., and Anderson K.C. Synopsis of a roundtable on validating novel therapeutics for multiple myeloma. Clin. Cancer Res. 12 (2006) 6603-6610
    • (2006) Clin. Cancer Res. , vol.12 , pp. 6603-6610
    • Dalton, W.1    Anderson, K.C.2
  • 39
    • 33744488766 scopus 로고    scopus 로고
    • Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance
    • Hoang B., Zhu L., Shi Y., Frost P., Yan H., Sharma S., Sharma S., Goodglick L., Dubinett S., and Lichtenstein A. Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance. Blood 107 (2006) 4484-4490
    • (2006) Blood , vol.107 , pp. 4484-4490
    • Hoang, B.1    Zhu, L.2    Shi, Y.3    Frost, P.4    Yan, H.5    Sharma, S.6    Sharma, S.7    Goodglick, L.8    Dubinett, S.9    Lichtenstein, A.10
  • 41
    • 33947280591 scopus 로고    scopus 로고
    • Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions
    • Anderson K.C. Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions. Exp. Hematol. 35 (2007) 155-162
    • (2007) Exp. Hematol. , vol.35 , pp. 155-162
    • Anderson, K.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.